International Journal of Applied Ceramic Technology
·
2018
·Vol. 15
·期 3
·783-791
·
IF 1.165
Yi Ding,Xinggui Long,Shuming Peng,Zhaoyi Tan,Dong Zhang,Xirui Lu
Ce-doped zirconia ceramics with general stoichiometry of Zr 1- x Ce x O 2 (0 ≤ x ≤ 1) have been obtained by substitution of Ce 4+ for Zr 4+ in ZrO 2 . The phase and microstructure evolutions of the ceramics were investigated, and the effects of composition, temperature, and pH value on the chemical durability of the ceramics were also studied. The results show that the phase transformation from monoclinic to tetragonal takes place at about x = 0.2, and from tetragonal to cubic at about x = 0.6. It is found that the increase in Ce content and/or sinter temperature promote the phase transformation. The leaching studies show that the normalized leaching rates of Ce (LR Ce ) increase with increasing Ce content. Moreover, LR Ce in acid solution are higher than those in neutral and alkaline solution. After 42 days, LR Ce is 10 −5 ~ 10 −7 g m −2 d −1 under all different leaching conditions, exhibiting their excellent chemical durability.
研究领域:
材料科学
·
无机化学
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JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
·
2023
·
IF 10.9
Mingxin Zhang,Cuiying Pei,Qi Wang,Yi Zhao,Changhua Li,Weizheng Cao,Shihao Zhu,Juefei Wu,Yanpeng Qi
Recently, the discovery of superconductivity with a critical temperature T c up to 80 K in Ruddlesden–Popper phases La n +1 Ni n O 3 n +1 ( n = 2) under pressure has garnered considerable attention. Up to now, the superconductivity was only observed in La 3 Ni 2 O 7 single crystal grown with the optical-image floating zone furnace under oxygen pressure. It remains to be understood the effect of chemical doping on superconducting La 3 Ni 2 O 7 as well as other Ruddlesden–Popper phases. Here, we systematically investigate the effect of external pressure and chemical doping on polycrystalline Ruddlesden–Popper phases. Our results demonstrate that the application of pressure and doping effectively tunes the transport properties of Ruddlesden–Popper phases. We find pressure-induced superconductivity up to 86 K in La 3 Ni 2 O 7 polycrystalline sample, while no signatures of superconductivity are observed in La 2 NiO 4 and La 4 Ni 3 O 10 polycrystalline samples under high pressure up to 50 GPa. Our study sheds light on the exploration of high- T c superconductivity in nickelates.
研究领域:
凝聚态物理
·
材料科学
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PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
·
2017
·
IF 0.809
Shaohua Zhu,Yan Zhang,Peipei Li,Wenzhu Bi,Xiaolan Chen,Yufen Zhao
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MOLECULAR REPRODUCTION AND DEVELOPMENT
·
2026
·Vol. 93
·期 7
·e70135
·
IF 2.6
Yang Sun,Haipeng Pei,Xing Zhang,Yi Jing,Ziheng Zhang,Xinghao Zhang,Huaying Qian,Fengjuan Chang,Yuhang Geng,Ziyang Han,Yun Chen
Pyroptosis, a proinflammatory form of programmed cell death mediated by the NLRP3 inflammasome, has recently been implicated in Sertoli cell inflammatory injury. Crocin, a water-soluble carotenoid glycoside derived from Crocus sativus L. and Gardenia jasminoides Ellis, exhibits anti-inflammatory, antioxidant, and anti-apoptotic properties, yet its role in Sertoli cell pyroptosis remains unclear. Here, we investigated the pharmacological effects and mechanisms of crocin in regulating TM4 Sertoli cell viability and pyroptosis. Network pharmacology based on oligoasthenospermia (OA)-related candidate targets, together with molecular docking, identified HSP90AA1 as a candidate molecular target associated with crocin-mediated regulation of Sertoli cell pyroptosis. MST analysis further provided target-engagement evidence supporting a direct interaction between crocin and HSP90AA1. In TM4 Sertoli cells, crocin improved cell viability, enhanced Ki-67 expression, and protected against lipopolysaccharide/nigericin-induced pyroptosis, as evidenced by reduced lactate dehydrogenase release, decreased PI-positive cells, and downregulated expression of IL-1β, IL-18, NLRP3, Caspase-1, and GSDMD. Moreover, under HSP90AA1-overexpressing conditions, crocin partially reduced pyroptosis-related injury and inflammatory mediator expression, supporting the involvement of HSP90AA1 in crocin-mediated regulation of Sertoli cell pyroptosis. Collectively, these findings indicate that crocin enhances Sertoli cell proliferation and mitigates inflammasome-driven pyroptosis through an HSP90AA1-associated mechanism. These findings should be interpreted as preliminary in vitro evidence for crocin-mediated regulation of Sertoli cell proliferation and pyroptosis, and further validation in animal models and clinical samples is required.
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PubMed
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CELL DEATH AND DIFFERENTIATION
·
2026
·
IF 13.6
Luan Jing,He Jiyuan,Wu Dantong,Duan Yaning,Hou Guoyuan,Ma Shuang,Qin Jianhua,Sun Na,He Yuanzheng,Zhang Wei,Gao Minghui
Ferroptosis is a type of regulated necrosis driven by iron-dependent lethal accumulation of lipid peroxides. Selenoprotein thioredoxin reductase (TrxR) plays crucial roles in cellular redox homeostasis. However, its role in ferroptosis remains unclear. Here, we report TrxR1 positively regulates ferroptosis. The selenocysteine of TrxR1 is required for its regulation of ferroptosis. Mechanistically, the CRL4A CRBN E3 complex ubiquitinates KEAP1 at K84 and K312, driving KEAP1 degradation. Overexpression of TrxR1 increases KEAP1 stability by suppressing CRL4A CRBN E3 complex mediated KEAP1 ubiquitination and degradation, enhances the interaction between NRF2 and KEAP1, promotes NRF2 ubiquitination and drives NRF2 degradation, which results in downregulation of GPX4 expression, thereby sensitizing cells to ferroptosis. Furthermore, high level of TrxR1 sensitizes cancer cells to ferroptosis in vivo. CRBN inhibitor thalidomide and IKE combination treatment results in markedly retarded tumor progression. Our study reveals a crucial pro-ferroptotic role for TrxR1 and nominates it as a potential biomarker for guiding future ferroptosis-inducing therapies in select cancers.
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MOLECULES
·
2026
·Vol. 31
·期 13
·2332
·
IF 5.1
Renkun Huang,Haohao Yan,Runling Huang,Chen Zhou,Qiuzhong Li,Lu Chen,Ruowen Liang
A novel composite catalyst for photothermal CO2cycloaddition was developed by integrating the ionic liquid 1-ethylpyridinium bromide (EPB) with a copper-based metal–organic framework (HKUST-1). HKUST-1 was synthesized via a hydrothermal method and functionalized with EPB through a wet impregnation strategy to enhance its catalytic performance. Under xenon lamp irradiation and optimized conditions (80 °C, 1 MPa CO2pressure, 12 h, and 0.07% mol of TBAB bromide as a co-catalyst), the HK@EPB composite exhibited outstanding performance in catalyzing the conversion of CO2and various epoxides into cyclic carbonates. The exceptional catalytic activity arises from a synergistic multicomponent mechanism: the incorporation of EPB not only enhances CO2adsorption capacity but also provides photothermal energy for the reaction; simultaneously, EPB dissociates bromide ions to effectively initiate epoxide ring-opening. In particular, propylene oxide achieved a selectivity of 95% for the desired cyclic carbonate, surpassing most previously reported MOF-based catalysts. This system enables efficient catalysis under mild conditions through the synergistic contributions of the high CO2adsorption capacity and Cu2+/Cu+redox-mediated electron transfer of HKUST-1, the provision of nucleophilic Br-species from EPB to promote epoxide ring-opening, and the cooperative effect of TBAB. This study demonstrates that ionic-liquid-functionalized MOF composites can serve as sustainable and versatile catalytic platforms, offering an environmentally friendly pathway for large-scale CO2utilization.
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POLYMER
·
2026
·
IF 5.1
Huifang Ma,Famin Liu,Yaping Ma,Chenguang Liu,Aihua He
Developing new-generation inner-lining materials with enhanced resistance to high temperatures and chemical corrosion is urgent for industrial reactors operating under harsh conditions. In this work, controlled degradation of isotactic polybutene-1 (PB) samples with decreased weight-average molecular weight ( M w ) and narrowed molecular weight distribution ( M w / M n ), significantly increased melt flow rate (MFR) were achieved through peroxide induced chemical degradation. The degraded PB specimens exhibited minor structural moieties, including C C double bonds and –CH(CH 2 –CH 3 )–CH(CH 2 –CH 3 )- groups. Four reaction pathways were proposed to elucidate the microstructural evolution of degraded PB specimens. The degraded PB specimens presented almost constant isotacticity (mmmm = 93-95%), melting temperature ( T m = 124-131 °C), crystallinity ( X c = 44-49%), and lamellar thickness ( d c ) around 10-13 nm for PB form Ⅰ. The degraded PB-5 exhibited excellent coating processability, as well as excellent high-temperature properties. Compared with commercial film-grade high-density polyethylene (HDPE), PB-5 showed 59% higher tensile strength, 55% lower creep deformation, and 73% higher resistance to alkali at 85 °C. The blade-coated PB-5 film exhibited the highest surface smoothness and better water vapor barrier property when compared with that of pristine PB and HDPE. This work presented a feasible strategy for the fabrication of degraded PB-5 with superior coating processability and excellent high-temperature properties, which are expected to be used as inner lining materials of industrial reactors.
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CHEMICAL PHYSICS LETTERS
·
2026
·
IF 2.9
Qingqing Yang,Chaosheng Yuan,Chenran Zhang,Xuerui Cheng,Haining Li,Yongfu Liang,Zheng Wang,Xiang Zhu,Lei Su
Phase transformations of 1-methylpiperidine under static and dynamic compression up to 21 GPa were investigated via in-situ Raman spectroscopy in a diamond anvil cell. Static compression reveals at least three crystalline phases and an amorphous state, which are kinetically sensitive and metastable. Dynamic compression rapidly induces amorphization, and subsequent decompression leads to spontaneous crystallization through Phase III and Phase II. The high-pressure phase behavior of 1-methylpiperidine is kinetically controlled rather than purely thermodynamic, governed by structural evolution, molecular flexibility, and metastable state formation.
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BioDesign Research
·
2026
·
IF 7.2
Haidong Yu,Haofeng Chen,Guojun Yang,Zhen Huang,Jieming Zhou,Dongjiang Lin,Junru Zhao,Yang Zhang,Jifeng Yuan
1-Butanol is a C4 aliphatic alcohol that is widely used as a gasoline blendstock. In this study, we report an underexplored metabolic route for the de novo biosynthesis of 1-butanol in Escherichia coli . Specifically, the 1-butanol biosynthetic pathway comprises a redesigned Clostridium -derived pathway for butyryl-CoA synthesis, followed by a CoA-acylating aldehyde dehydrogenase (PduP from Salmonella enterica ) and an endogenous alcohol dehydrogenase (YqhD from E. coli ). We found that abolishing thioesterases to block the formation of butyrate byproduct would lead to deleterious effects on the cell growth. Upon introducing a metabolic buffering pathway towards polyhydroxyalkanoate biosynthesis, the toxicity caused by metabolic imbalance was alleviated, accompanied by enhanced cell growth and 1-butanol productivity. A similar strategy was also validated to be effective for improving the production of hexane-2,3-diol, a potential cosmetic component with high value. In summary, this work successfully demonstrates that the metabolic buffering strategy exerts a synergistic effect on enhancing biochemical production with improved carbon recovery efficiency.
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Nature Communications
·
2026
·
IF 18.1
Du Yuxiang,Xiu Yueyue,Yang Xin,Fu Rui,Liu Dan,Liu Lipeng,Sai Huazheng
Aerogels exhibit excellent properties owing to their nano-sized building blocks and unique structures. With increasing application demands, traditional nanoscale building blocks have limitations in further optimizing the performance of aerogels; therefore, the development of novel, high-performance building blocks has become an urgent challenge in the field. Sub-1 nm nanowires (SNWs) exhibit polymer-like properties that make them superior to nanoscale nanowires, and are well-suited as new building blocks for aerogels. In this study, we achieved precise control over the aggregation state of GdOOH SNWs (Gd–SNWs) in three-dimensional space by regulating the interactions between SNWs as well as between SNWs and solvents, thereby obtaining SNW aerogels (SNWAs) with low density ( ~ 0.024 g cm −3 ) and high specific surface area (505 m 2 g −1 ). After silanization, the superhydrophobic SNWAs exhibited excellent fatigue resistance (50 cycles with a set strain of 50%). This innovative approach enriches the types of aerogels building blocks and opens up new avenues for high-performance aerogels.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2026
·Vol. 37
·期 22
·1787
·
IF 3.2
Zhang Qiuyang,Liu Guixiang,Dai Bo,Liu Kuan,Wang Wei,Ren Yong,Xu Fang
To satisfy the combined magnetic and dielectric requirements of electromagnetic materials for modern communication systems, (1- x )Y 3 Fe 5 O 12 - x BaTiO 3 (YIG-BTO) multiphase ceramics were prepared via a conventional ceramic processing method. The phase composition, element distribution, microstructure, and magnetic and dielectric properties of the samples were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), vibrating sample magnetometry (VSM), and a precision impedance analyzer. The results indicate that, at the microscale, the YIG and BTO phases coexist uniformly within the YIG-BTO composite ceramics. The microstructure, relative density, and grain size of the YIG-BTO ceramics are closely related to the BTO content, which in turn synergistically affects their magnetodielectric properties. For the 90 wt% YIG-10 wt% BTO ceramic sample with a relative density ( ρ r ) exceeding 95%, an optimal overall magnetodielectric performance is achieved. At 100 kHz, the initial permeability ( μ′ ) is 39.08, the magnetic loss ( tanδ μ ) is 0.1, the dielectric constant ( ε r ) is 29.32, the dielectric loss ( tanδ ε ) is 0.071, and the saturation magnetization ( 4πMs ) is 1563.67 Gs. This study provides a systematic theoretical basis for the practical application of the promising YIG-BTO multiphase material system.
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CERAMICS INTERNATIONAL
·
2021
·
IF 4.527
Jinpeng Ma,Ke Zhu,Da Huo,Bingzhong Shen,Yang Liu,Xudong Qi,Enwei Sun,Rui Zhang
The performances of 1–3 piezocomposite materials under various poling conditions were compared and analysed. The dielectric , piezoelectric , and electromechanical properties of 1–3 piezocomposite materials were studied with variations in the electric field amplitude ( E p ), poling frequency ( f ), and number of cycles ( C ). It was found that the piezoelectric coefficient ( d 33 ), free dielectric constant ( ε 33 T / ε 0 ), and electromechanical coupling factor ( k t ) of 1–3 piezocomposite materials exhibit an increase of 21.4%, 13%, and 10.7%, respectively, under the optimum alternating current poling (ACP) condition ( f = 1.25 Hz, E p = 2 kV/mm, C = 16), compared with that of the samples poled using the direct current polarisation (DCP) method. The studies of the domain pattern indicate that the performance enhancement originates from the remarkable regularly striped domain structure and high domain wall density in ACP-poled samples. Our results suggest that the ACP method is effective in enhancing the performance of composite piezoelectric materials , which possess great benefits and potential for application in acoustic/medical transducers.
研究领域:
材料科学
·
声学工程
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高影响因子
危险品化学品经营许可证（带存储）