CHEMICAL ENGINEERING JOURNAL
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2022
·
IF 16.744
Kang An,Siran Zhang,Hong Wang,Ningyan Li,Ziyang Zhang,Yuan Liu
Direct hydrogenation of CO 2 into ethanol has been considered as an up-and-coming way to achieve CO 2 utilization. Ethanol can be generated by reverse water gas shift as well as CO hydrogenation over Co-based catalysts, where the regulation of Co 0 − Co δ+ is critical. Herein, we designed a supported Co-based catalyst doped with gallium, which was derived from Co-Al-O spinel precursor to facilitate synergistic catalyzing for CO 2 -to-ethanol transformation. The selectivity of ethanol reached 20.1 % in a continuous flow fixed micro-reactor over reduced CoGa 1.0 Al 1.0 O 4 /SiO 2 catalyst at 270 °C and 3.0 MPa. Results of characterization show that the existence of the strong interaction between Ga oxide and cobalt induced the configuration of Co 0 − Co δ+ active pairs, which promotes the process of ethanol synthesis by coupling the dissociation (CH x *)/non-dissociation (CO*) of the intermediates. The strategy by tuning the interaction between cobalt and gallium and/or aluminum oxide brings an avenue to tailor Co 0 − Co δ+ active pairs for the hydrogenation of CO and CO 2 .
研究领域:
催化化学
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能源化学
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材料化学
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环境化学
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工业催化
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高影响因子
MEDICINAL CHEMISTRY RESEARCH
·
2017
·Vol. 26
·期 3
·672-679
·
IF 1.277
Liu Zhenbao,Wang Xiaohong,Zhang Hang,Zhang Shanshan,Li Yiqian,Liu Yanfei,Peng Dongming
Berberine owns multiple pharmacological activities, especially anti-inflammatory activity. To enhance the anti-inflammatory therapeutic efficiency of berberine, a series of novel 9- O -substituted berberine derivatives ( 5a – 5d ) were synthesized and their anti-inflammatory activities were evaluated. 13 C-NMR, 1 H-NMR, IR and high resolution mass spectrum (HRMS) results indicated that these derivatives were successfully synthesized. The xylene-induced inflammatory mice model demonstrated that these derivatives showed dose-dependent inhibition of ear inflammatory swelling. Comparing to berberine, ibuprofen and naproxen-modified berberine derivatives enhanced anti-inflammatory activities, while aspirin and nicotinic acid-modified berberine derivatives showed lower anti-inflammatory effects at the same dosages. This could be attributed to the enhanced inhibition of secretion of cytokines, including interleukin-6 and tumor necrosis factor-α, by ibuprofen and naproxen berberine derivatives, while aspirin and nicotinic acid berberine derivatives showed lower inhibition of tumor necrosis factor-α than berberine. These results suggest that ibuprofen and naproxen-modified berberine derivatives are promising new anti-inflammatory drug candidates.
研究领域:
药物化学
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炎症研究
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生物合成
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2013
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IF 3.473
Manhong Liu,Qiang Bai,Hailian Xiao,Yanyan Liu,Jun Zhao,William W. Yu
Colloidal platinum–ruthenium bimetallic nanoparticles with 2.3 nm were synthesized in solution and then immobilized on tin dioxide powder to make a supported nanocatalyst (Pt–Ru/SnO 2 ). The immobilized bimetallic nanoparticles had the same size and size distribution as the solution dispersed ones. Selective hydrogenation of o -chloronitrobenzene to o -chloroaniline was performed over the as-prepared Pt–Ru/SnO 2 nanocatalyst without using any solvent; 99.5% selectivity to o -chloroaniline at ∼100% conversion was achieved.
研究领域:
催化化学
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纳米材料
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有机合成
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绿色化学
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应用化学
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DOI
高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2023
·Vol. 415
·期 8
·1545-1557
·
IF 4.3
Ding Minling,Niu Huizhe,Guan Ping,Hu Xiaoling
A sensitive and selective molecularly imprinted polymer (MIP) sensor was developed for the determination of amyloid-β (1–42) (Aβ 42 ). The glassy carbon electrode (GCE) was successively modified with electrochemical reduction graphene oxide (ERG) and poly(thionine-methylene blue) (PTH-MB). The MIPs were synthesized by electropolymerization with Aβ 42 as a template and o-phenylenediamine (o–PD) and hydroquinone (HQ) as functional monomers. Cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), chronoamperometry (CC), and differential pulse voltammetry (DPV) were used to study the preparation process of the MIP sensor. The preparation conditions of the sensor were investigated in detail. In optimal experimental conditions, the response current of the sensor was linear in the range of 0.12–10 μg mL −1 with a detection limit of 0.018 ng mL −1 . The MIP-based sensor successfully detected Aβ 42 in commercial fetal bovine serum (cFBS) and artificial cerebrospinal fluid (aCSF).
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DOI
PubMed
高影响因子
INORGANIC CHEMISTRY COMMUNICATIONS
·
2023
·
IF 3.8
Xin Yan,Chaoli Wang,Tao Ai,Zhuo Li,Yanhui Niu
The porous (Co 0.2 Cu 0.2 Mg 0.2 Ni 0.2 Zn 0.2 )O high entropy oxide was synthesized by a facile solution combustion method. The X-ray diffraction (XRD) patterns showed that a rock-salt phase (Co 0.2 Cu 0.2 Mg 0.2 Ni 0.2 Zn 0.2 )O nanocrystalline was successfully constructed after heat treatment above 800 °C. A porous microstructure with high specific surface area was determined by scanning electron microscope (SEM) and N 2 adsorption analysis, respectively. The (Co 0.2 Cu 0.2 Mg 0.2 Ni 0.2 Zn 0.2 )O high entropy oxide displayed excellent peroxymonosulfate (PMS) activation which could fully degrade the tetracycline (TC) within 24 min. Moreover, the effect of PMS concentration, the high entropy oxide dosage, pH value, temperature and coexisting anions on the degradation efficiency of TC was systematically studied. According to free radical quenching experiments and electron paramagnetic resonance studies, the possible mechanism of TC degradation over the (Co 0.2 Cu 0.2 Mg 0.2 Ni 0.2 Zn 0.2 )O/PMS system was proposed. This work provided a research basis for the use of high entropy oxide for PMS activation in environmental treatment.
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高影响因子
Foods
·
2023
·Vol. 12
·期 5
·1068
·
IF 5.2
Meixiang Yao,Xin Qi,Jiahui Zhang,Chengyuan Wang,Jianhua Xie
Mesona chinensispolysaccharide (MCP), a common thickener, stabilizer and gelling agent in food and pharmaceuticals, also has antioxidant, immunomodulatory and hypoglycemic properties. Whey protein isolate (WPI)-MCP conjugate was prepared and used as a stabilizer for O/W emulsion in this study. FT-IR and surface hydrophobicity results showed there could exist interactions between -COO- in MCP and -NH3+in WPI, and hydrogen bonding may be involved in the covalent binding process. The red-shifted peaks in the FT-IR spectra suggested the formation of WPI-MCP conjugate, and MCP may be bound to the hydrophobic area of WPI with decreasing surface hydrophobicity. According to chemical bond measurement, hydrophobic interaction, hydrogen bond and disulfide bond played the main role in the formation process of WPI-MCP conjugate. According to morphological analysis, the O/W emulsion formed by WPI-MCP had a larger size than the emulsion formed by WPI. The conjugation of MCP with WPI improved the apparent viscosity and gel structure of emulsions, which was concentration-dependent. The oxidative stability of the WPI-MCP emulsion was higher than that of the WPI emulsion. However, the protection effect of WPI-MCP emulsion on β-carotene still needs to be further improved.Keywords:Mesona chinensispolysaccharide;whey protein isolate;conjugate;emulsion
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高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2023
·
IF 8.2
Qin Geng,David Julian McClements,Zhihua Wu,Ti Li,Xuemei He,Xixiang Shuai,Chengmei Liu,Taotao Dai
Procyanidins are bioactive polyphenols that have a strong affinity to proteins. Beta-lactoglobulin (BLG) is widely used as an emulsifier in the food and other industries. This study evaluated the interaction between BLG and A-type procyanidin dimer (PA2) using the spectroscopic, thermodynamic, and molecular simulation. PA2 decreased the transmissivity and quenched the intrinsic fluorescence of BLG, suggesting that the two molecules formed a complex. The binding of PA2 reduced the surface hydrophobicity and altered the conformation of BLG with increasing the random coil regions. Thermodynamic and isothermal titration calorimetry analyses suggested that the main driving force of PA2-BLG interaction was hydrophobic attraction. Molecular docking simulations were used to identify the main interaction sites and forces in the BLG-PA2 complexes, which again indicated that hydrophobic interactions dominated. In addition, the influence of PA2 on the ability of BLG to form and stabilize O/W emulsions was analyzed. Emulsions formulated using BLG-PA2 complexes contained relatively small droplets (D 4,3 ≈ 0.7 μm) and high surface potentials (absolute value >50 mV). Compared to BLG alone, BLG-PA2 complexes improved the storage stability of the emulsions. This study provides valuable new insights into the formation, properties, and application of protein-polyphenol complexes as functional ingredients in foods.
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PubMed
高影响因子
Nanomaterials
·
2023
·Vol. 13
·期 7
·1188
·
IF 5.3
Lina Sun,Liping Sun,Lihua Huo,Hui Zhao
H2O2generation via an electrochemical two-electron oxygen reduction (2e−ORR) is a potential candidate to replace the industrial anthraquinone process. In this study, porous carbon catalysts co-doped by nitrogen and oxygen are successfully synthesized by the pyrolysis and oxidation of a ZIF-67 precursor. The catalyst exhibits a selectivity of ~83.1% for 2e−ORR, with the electron-transferring number approaching 2.33, and generation rate of 2909.79 mmol g−1h−1at 0.36 V (vs. RHE) in KOH solution (0.1 M). The results prove that graphitic N and –COOH functional groups act as the catalytic centers for this reaction, and the two functional groups work together to greatly enhance the performance of 2e−ORR. In addition, the introduction of the –COOH functional group increases the hydrophilicity and the zeta potential of the carbon materials, which also promotes the 2e−ORR. The study provides a new understanding of the production of H2O2by electrocatalytic oxygen reduction with MOF-derived carbon catalysts.Keywords:porous carbon;two-electron reduction of oxygen;hydrogen peroxide;electrocatalyst
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PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2023
·Vol. 140
·期 10
·e53590
·
IF 3
Sisi Yuan,Yongjun Wang,Xiujun Wang,Donghua Liao,Ming Duan,Shenwen Fang
The block polyether demulsifier prepared by ring-opening polymerization of ethylene oxide and propylene oxide under high temperature and high pressure is the most widely used demulsifier for water in crude oil emulsion. It has the high synthesis risk and cost. Therefore, the development of non-block polyether demulsifier has attracted more and more attention. In this article, a new type of demulsifier was sythesized by radical polymerization of acrylate and cationic monomer. It was found that the copolymer PMA-co-PDBC of methyl acrylate (MA) and benzyldimethyl [2-[(1-oxoallyl)oxy] ethyl] ammonium chloride (DBC) synthesized in the mixed solvent of dipropylene glycol methyl ether and water had a good performance. When dosage of PMA-co-PDBC was 200 mg/L, the dehydration rate of water in crude oil emulsion with 50% water content can reach 80% at 80°C within 4 h. Structural and interface properties analysis presented that PMA-co-PDBC had a microblock structure similar with block polyether and it can effectively reduce the strength of W/O interfacial film to realize the demulsification. Although the demulsification performance of PMA-co-PDBC was not better than block polyether, its preparation safety and cost are much better. The results of this article can provide a new option for the development of crude oil demulsifier.
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高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2023
·Vol. 140
·期 10
·e53594
·
IF 3
Zejun Zhang,Fan Ye,Guosheng Ai,Huanyu Liu,Guanxin Zeng,Liwei Shen,Ying Yang,Huaikui Yuan,Xuening Feng,Yuanzhu Mi
A highly branched PNDC demulsifier with 2,6-naphthalenedicarboxylate as centronucleus was prepared by an efficient “one-pot” strategy. The product was characterized by FT-IR, 1 H-NMR, and TGA. The bottle test was performed to explore the effect of temperature, settling time, pH value, and concentration on the demulsification efficiency (DE). The DE reached an optimal value of 94.63% when the concentration of PNDC, settling time and operated temperature were 100 mg/L, 60 min and 70°C, respectively. Also, the DE could reach 91.58% when the concentration was only 20 mg/L at the same conditions. It showed that PNDC had an excellent performance in W/O emulsions with an extremely low concentration. Especially, PNDC could be used over a wide pH range (4–12) and high salinities, indicating that it had a good salt, acid and alkaline tolerance. In addition, the interfacial tension (IFT), surface tension (SFT), elastic modulus and micrograph analysis were carried out to investigate the possible mechanism. This work provides a highly branched demulsifier with high DE for the demulsification of stable W/O emulsions.
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高影响因子
MOLECULES
·
2023
·Vol. 28
·期 24
·8013
·
IF 4.6
Yuzhou Xia,Xinghe Xia,Shuying Zhu,Ruowen Liang,Guiyang Yan,Feng Chen,Xuxu Wang
Visible-light-driven N2reduction into NH3in pure H2O provides an energy-saving alternative to the Haber–Bosch process for ammonia synthesizing. However, the thermodynamic stability of N≡N and low water solubility of N2remain the key bottlenecks. Here, we propose a solution by developing a WO3−xhollow sphere with oxygen vacancies. Experimental analysis reveals that the hollow sphere structure greatly promotes the enrichment of N2molecules in the inner cavity and facilitates the chemisorption of N2onto WO3−x-HS. The outer layer’s thin shell facilitates the photogenerated charge transfer and the full exposure of O vacancies as active sites. O vacancies exposed on the surface accelerate the activation of N≡N triple bonds. As such, the optimized catalyst shows a NH3generation rate of 140.08 μmol g−1h−1, which is 7.94 times higher than the counterpart WO3-bulk.Keywords:WO3;hollow sphere;O defect;N2reduction;photocatalysis
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PubMed
高影响因子
FOOD HYDROCOLLOIDS
·
2022
·
IF 11.504
Zhiming Gao,Chen Gao,Wenxin Jiang,Longquan Xu,Bing Hu,Xiaolin Yao,Yanlei Li,Yuehan Wu
It has been a great challenge of using natural polysaccharides to stabilize food emulsions , due to their poor amphiphilicity. In this study, a novel strategy of using polysaccharide to stabilize O/W emulsions was developed, through in situ crosslinking of sodium alginate on oil-water interface. During the emulsifying process, the acetic acid migrated across the interface, and induced the released of calcium ions , which immediately crosslinked the sodium alginate on interface. Results showed that the oil droplets were encapsulated in the integral polysaccharide shells. The droplet size of the emulsions located in the range from 20 to 200 μm. The concentration of sodium alginate and HAc, as well as the mixing rates were showed to be positively related with the thickness of the shell. However, excess calcium ions would disintegrate the shell structure. Additionally, the interfacial crosslinked sodium alginate stabilized emulsions exhibited excellent physical stability under centrifugating and freeze-thawing.
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高影响因子
危险品化学品经营许可证（带存储）