SEPARATION AND PURIFICATION TECHNOLOGY
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2026
·
IF 9.1
Mengchen Li,Shuo Gao,Shunlong Xu,Junsu Jin,Junteng Liu,Hong Meng
Atmospheric water harvesting has emerged as a promising approach for addressing freshwater scarcity in arid regions. However, conventional hygroscopic salts suffer from leakage and agglomeration, while powder adsorbents often exhibit severe packing limitations that hinder vapor transport. Herein, a spherical composites adsorbent (KMF-1@LiCl-SA) was developed by confining LiCl within the pores of the KMF-1 and further shaping the composites using a sodium-alginate–based crosslinked network. Notably, the composites can be simply synthesized through a mild and scalable preparation process, which is advantageous for practical large-scale applications. The confinement of LiCl within KMF-1 pores enhances water adsorption under low humidity, while the three-dimensional porous SA network effectively prevents particle agglomeration and improves vapor diffusion pathways. As a result, the composites exhibits a high-water uptake of 0.826 g g −1 at 298 K and 30% RH, which is 2.75 times higher than pristine KMF-1. Dynamic adsorption experiments reveal that the shaped composites delivers a water vapor adsorption rate of 0.92 g g −1 h −1 under an airflow of 1780 mL min −1 at 298 K and 22% RH, representing a 60 times enhancement compared with static adsorption under identical conditions, thereby underscoring its promise for practical AWH applications. More importantly, the shaped spherical adsorbent significantly alleviates the packing effect compared with powdered materials, leading to improved adsorption kinetics under practical loading conditions. The material also demonstrates excellent adsorption–desorption reversibility, cycling stability, and structural robustness. This work provides a practical strategy for integrating salt-confined MOFs with polymer shaping networks to develop high-performance adsorbents for AWH.
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高影响因子
Microbiology Spectrum
·
2025
·
IF 3.8
Fan Yang,Wei Dai,Hua Xue,Wen Chen,Chen Liu,Yaru Tian,Wanli Cheng,Jibin Zhang
Root-knot nematodes (RKNs) are notoriously challenging to control because of their broad host spectrum and swift proliferation. Consequently, there is an urgent need to develop safe and effective nematicides. Microorganisms and their metabolites have the potential to control RKNs safely and effectively. Paenibacillus polymyxa KM2501-1 can produce a range of volatile organic compounds (VOCs) with nematicidal activities, among which 2-undecanol is a potential biocontrol agent against Meloidogyne incognita. Nonetheless, the mechanism by which 2-undecanol prevents RKN infection in plant roots remains unclear. 2-Undecanol has many activities against M. incognita in vitro, including contact (LC50 = 34.5 mg/L), fumigation (LC50 = 191.6 mg/L), attraction, locomotion inhibition (frequency of head thrash and body bend reduced by 84.0% and 97.0% at concentration of 40 mg/L) and egg hatching inhibition (by 98.5% at concentration of 80 mg/L). Upon treatment with 2-undecanol, a noticeable reduction in the number of galls was observed, and the control efficacy reached 60.8% at the dose of 5 mg/pot. Metabolomics analysis revealed that the application of 2-undecanol significantly influenced the composition of root exudates of tomato. Among the 17 differential metabolites, the up-regulated 10-undecenal could attract and kill M. incognita J2 larvae at a concentration of 100 mg/L, and cyclohexylamine had nematicidal activity at the concentration of 1,000 mg/L. This study revealed the mechanism of 2-undecanol inducing plant roots to secrete nematicidal substances with attractant activity, effectively controlling RKNs, which could pave the way for the development of environmentally friendly and cost-effective nematicides.
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PubMed
高影响因子
ACS Catalysis
·
2025
·
IF 13.1
Limin Zhang,Huahua Fan,Miao Zhang,Haoqing Zhang,Hao Wang,Bangjian Liu,Jiaxing Zhang,Xiaowa Nie,Guanghui Zhang,Chunshan Song,Xinwen Guo
Cobalt-based catalysts have recently emerged as a promising frontier in propane dehydrogenation (PDH) research. Despite their potential, achieving selective suppression of nonselective metallic cobalt (Co0) species remains a critical challenge. In this work, we report a hollow zeolite architecture (Co@S-1-Hol) that effectively addresses this dilemma through spatial confinement engineering. Through depth-profiling XPS analysis complemented by H2-TPR and UV–vis spectroscopy characterization, we demonstrate a unique cobalt valence distribution where metallic Co0 species are preferentially encapsulated within hollow cavities, while Co2+ ions remain atomically dispersed in the zeolite shell matrix. DFT calculations coupled with kinetic studies reveal that the cavity-confined Co0 clusters serve as the predominant active centers for C–H bond activation. Notably, STEM-EDS mapping and TGA uncover a self-regulating mechanism: the hierarchical hollow structure facilitates rapid and selective coking on nonselective surface sites during initial reaction phases, effectively passivating undesirable side reactions while preserving intrinsic catalytic activity. This spatial engineering strategy endows the Co@S-1-Hol catalyst with superior PDH performance compared to the conventional impregnated Co/S-1 catalyst, exhibiting an enhanced C3H6 formation rate (21.6 mmol gcat–1 h–1, equivalent to 1330 mmol gCo–1 h–1) coupled with a significantly reduced deactivation rate. Under optimized conditions at 550 °C, the catalyst achieves 35% propane conversion with 95% propylene selectivity, representing state-of-the-art performance among reported cobalt-based PDH catalysts. This work not only provides fundamental insights into cobalt active site engineering but also establishes a paradigm for designing spatially modulated zeolite catalysts in alkane dehydrogenation applications.
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JOURNAL OF MATERIALS CHEMISTRY
·
2011
·Vol. 21
·期 18
·6569-6575
·
IF 5.101
Xintao Luo,Jishu Han,Yang Ning,Zhe Lin,Hao Zhang,Bai Yang
1-Thioglycerol (TG)-stabilized quantum dots (QDs) are good candidate for performing a stepwise polymerization reaction with polyurethane (PU) prepolymers, but their use is limited by their worse photoluminescence (PL) in comparison to QDs stabilized by other mercapto-ligands. To overcome this problem, TG-stabilized CdTe QDs with enhanced PL were synthesized in water through a N2H4-promoted growth approach. The current synthesis significantly shortened the duration of the size evolution of QDs, particularly for obtaining samples with orange and red emissions. It also permitted QD growth at low temperatures, such as room temperature, which avoided the decomposition of TG and subsequent embedment of sulfur into the QDs as occurs in the conventional synthesis. Most importantly, the TG ligand endowed the QDs with hydroxyl coverage, making the QDs miscible with PU prepolymers in dimethyl sulfoxide, and therefore overcoming the main problem in fabricating PU-based nanocomposites of eliminating water. The hydroxyl coverage further allowed for the linkage of PU on the surface of the QDs through the reaction between –OH and –NCO, producing CdTe QD–PU bulk nanocomposites. Systematic characterization indicated that the QDs were well dispersed in the PU medium, and the size-dependent PL of QDs was also maintained.
研究领域:
材料科学
·
纳米科技
·
高分子化学
·
光电子学
·
胶体与界面化学
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高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2013
·
IF 2.004
Guofeng Xue,Hui Wan,Lei Wang,Guofeng Guan
Vapor–liquid equilibrium (VLE) data for binary systems of 2-methyl-1-butanol with ethylbenzene and xylene isomers are isobarically obtained with a modified Rose still at 101.33 kPa, as well as for the quinary system of 2-methyl-1-butanol + ethylbenzene + xylene isomers. The binary VLE data are considered to be thermodynamically consistent according to the Herington method and the point-to-point test. Taking the nonideality of the vapor phase into consideration, the activity coefficients are calculated. All systems show positive deviation from ideality. The VLE data are correlated using the nonrandom two-liquid (NRTL), universal quasichemical activity coefficient (UNIQUAC), and Wilson models. The calculated vapor-phase compositions and temperature agree well with the experimental values. The obtained model parameters of the binary systems are used to predict the VLE data for the quinary system. The results indicate that these three models allow a good prediction of the phase equilibrium for the quinary system.
研究领域:
化学工程
·
热力学
·
分离过程
·
相平衡
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高影响因子
TURKISH JOURNAL OF CHEMISTRY
·
2022
·Vol. 43
·期 5
·1290-1305
·
IF 1.151
TOK FATİH,KAYMAKÇIOĞLU BEDİA,İLHAN RECEP,YILMAZ SİNEM,KIRMIZIBAYRAK PETEK BALLAR,TOK TUĞBA TAŞKIN
Poly (ADP-ribose) polymerase (PARP) enzyme catalyzes the transfer of ADP-ribose into target proteins. Therefore, PARP is responsible for DNA repair, cell proliferation, and cell death. In this study, potential PARP enzyme inhibitors were designed and synthesized. The synthesized compounds were elucidated by Fourier-transform infrared spectroscopy, $^{1}$H NMR, $^{13}$C NMR, heteronuclear single-quantum correlation, and mass spectrometry, and their purity was checked via thin-layer chromatography, high-performance liquid chromatography, and elemental analysis. A total of 63 newly synthesized compounds were screened in terms of PARP inhibition by cellular PARylation assay in the HeLa cell line. It was found that 19 compounds significantly inhibited the H$_{2}$O$_{2}$-induced cellular PARylation. The chemosensitizer effect of these compounds in cancer cells treated with doxorubicin (doxo) was investigated. It was found that the combination of potent PARP inhibitors with doxo potentiated a cytotoxic effect, similar to that of olaparib. The results of the molecular docking and absorption, distribution, metabolism, excretion, and toxicity (ADMET) analysis revealed that compound 60 might be classified as a potential PARP inhibitor candidate. Taken together, all of the results suggested that carbohydrazide derivatives could be a promising lead for the treatment for cancer disorders.
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高影响因子
WATER AIR AND SOIL POLLUTION
·
2026
·Vol. 237
·期 10
·572
·
IF 3.5
Zhang Jian,Wang Ningruo,Xie Xuewen,Liao Siyi,Zhong Biao,Feng Bo,Tian Chunxiang,Xu Yajun,Chen Yuhan,Xiao Jiewen
This study systematically evaluates the efficiency and mechanism of Mn–Co bimetallic oxides for peroxymonosulfate (PMS) activation to degrade bisphenol AF (BPAF). A series of spherical Mn a Co (1-a) O x catalysts were synthesized via a facile hydrothermal method. Among them, Mn 0.2 Co 0.8 O x exhibited the highest catalytic activity, outperforming other ratios. Under optimized conditions ([BPAF] = 5 mg/L, [PMS] = 0.2 mM, [Mn 0.2 Co 0.8 O x ] = 400 mg/L, pH = 7.85), the Mn 0.2 Co 0.8 O x /PMS system achieved 97.7% BPAF removal. Quenching tests and EPR spectroscopy confirmed SO 4 •⁻ and •OH as the predominant reactive oxygen species, with SO 4 •⁻ playing the dominant role. XPS and mechanism analysis indicated that the synergistic Co(III)/Co(II) and Mn(III)/Mn(II) redox cycles drive the efficient PMS activation and BPAF degradation.
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高影响因子
PHYSICAL REVIEW B
·
2024
·Vol. 109
·期 21
·214430
·
IF 3.2
Lei Yue,Ziyou Lu,Kun Yan,Le Wang,Shu Guo,Ruixin Guo,Peng Chen,Xiaobin Chen,Jia-Wei Mei
In our study, we conduct magnetization and heat capacity measurements to investigate field-induced magnetic phase transitions within the newly synthesized compound ${\mathrm{K}}_{2}{\mathrm{Ni}}_{2}{({\mathrm{SeO}}_{3})}_{3}$, a spin-1 dimer system arranged on a triangular lattice. From our first-principles simulations, we determine that the spin system in ${\mathrm{K}}_{2}{\mathrm{Ni}}_{2}{({\mathrm{SeO}}_{3})}_{3}$ can be represented as a two-dimensional triangular-lattice spin-1 dimer model, including an intra-dimer exchange of ${J}_{1}=0.32\phantom{\rule{0.16em}{0ex}}\mathrm{meV}$, an inter-dimer exchange of ${J}_{2}=0.79\phantom{\rule{0.16em}{0ex}}\mathrm{meV}$, and an easy-axis anisotropy of $D=0.14\phantom{\rule{0.16em}{0ex}}\mathrm{meV}$. The presence of easy-axis magnetic anisotropy explains the distinct magnetic phase diagrams observed under $c$-axis directional and in-plane magnetic fields. Notably, our investigation unveils a two-step phase transition with the magnetic field aligned with the $c$ direction. Our findings yield valuable insights into the magnetic phase transitions inherent to geometrically frustrated magnetic systems featuring dimer structures.
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高影响因子
Frontiers in Pharmacology
·
2026
·
IF 5.4
Chen Bao,Decai Wang,Chao Liu,Meizhou Zhang,Qian Liu,Jiannan Hu,Yuzhou Wu,Shuyun Xu
Ferroptosis is an iron-dependent programmed cell death mechanism triggered by the accumulation of lipid-based reactive oxygen species (ROS). It is closely implicated in the pathogenesis of asthma. Liproxstatin-1 (LIP-1) is a ferroptosis inhibitor that is beneficial for treating neutrophilic asthma. However, low water solubility, limited blood concentration, and poor mucus permeability and biocompatibility limit the therapeutic efficacy of LIP-1. In this study, we successfully constructed polydopamine–polyethylene glycol–LIP-1 nanoparticles (PDA-PEG-LIP-1 NPs) for the treatment of neutrophilic asthma. Inhalation of PDA-PEG-LIP-1 NPs effectively inhibited lipopolysaccharide (LPS)- and interleukin (IL)-13-induced ferroptosis by alleviating lipid peroxidation and ROS production and chelating free ferrous ions (Fe 2+ ). In addition, results from asthma mouse models demonstrated that inhalation of PDA-PEG-LIP-1 NPs could overcome the limitations of LIP-1 and effectively inhibit ferroptosis. This research suggests that PDA-PEG-LIP-1 NPs are an effective, practical, and safe option for treating neutrophilic asthma.
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DOI
PubMed
高影响因子
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
·
2026
·
IF 5
Qi Lou,Rui Bai,Yongwu Liu,Bo Li,Haoran Zhu,Guangzhong Liu
Reports indicate that MARCHF6 can regulate ferroptosis. • The high expression of MARCHF6 alleviates myocardial ischemia-reperfusion injury. • Elevated MARCHF6 expression inhibits ferroptosis in CMECs. • MARCHF6 regulates ferroptosis through the ADAMTS4/SDC-1 pathway. • MARCHF6 is a promising therapeutic target for MIRI. Myocardial ischemia-reperfusion injury is a key factor affecting prognosis after acute myocardial infarction. MARCHF6, as an E3 ubiquitin ligase, is closely implicated in the ferroptosis process. The role of MARCHF6 in MIRI and its mechanism for regulating myocardial cell ferroptosis remained unclear. A mouse model of MIRI overexpressing MARCHF6 was established by tail vein injection of MARCHF6-overexpressing AAV9 virus, followed by left anterior descending coronary artery ligation surgery in mice. High expression of MARCHF6 significantly improved cardiac function and reduced myocardial injury in MIRI mice. Compared with the MIRI mice, the MARCHF6 overexpression mice exhibited a reduction of approximately 14% in myocardial infarction area. Histological damage in the cardiac ischemic penumbra region was markedly alleviated, and the number of cell deaths was significantly decreased. Concurrently, MARCHF6 overexpression substantially reduced serum levels of myocardial injury markers CK-MB, cTnI, and LDH. Mitochondrial morphological alterations and expression of ferroptosis-related indicators in the ischemic penumbra of the heart indicated that MARCHF6 overexpression alleviated ferroptosis in MIRI hearts. In an OGD/R-induced cardiomyocyte microvascular endothelial cell (CMEC) model, MARCHF6 overexpression alleviated lipid peroxidation and inhibited ferroptosis. MARCHF6 overexpression suppressed the upregulation of ACSL4 and 4-HNE while blocking the downregulation of SLC7A11 and GPX4 in vivo and vitro . Mechanistically, MARCHF6 promoted the ubiquitin-mediated degradation of ADAMTS4, thereby upregulating its downstream target SDC-1. This sequence of events inhibits lipid peroxidation, mitigates mitochondrial damage, and ultimately blocks the ferroptosis process in endothelial cells. These findings unveil a novel regulatory pathway involving MARCHF6/ADAMTS4/SDC-1 against MIRI by inhibiting ferroptosis. Download: Download high-res image (104KB) Download: Download full-size image
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JOURNAL OF MEMBRANE SCIENCE
·
2026
·
IF 8.8
Hui-Qian Huo,Bing-Xin Gu,Hui-Ting Zhang,Jin-Lin Wang,Jia-Chen Zhang,Yan-Li Ji,Quan-Fu An
Organic solvent nanofiltration (OSN) membranes are critically important for the efficient and sustainable separation of active pharmaceutical ingredients (APIs) from low-molecular-weight genotoxic impurities (GTIs). However, conventional polymer OSN membranes face significant technical challenges in improving APIs separation accuracy due to their inherent chain flexibility and undefined pore structure. Herein, we report an imidazole-based nanoparticle (MZP)-mediated confined crystallization strategy to fabricate MZP@HKUST-1 nanocomposite membranes with rigid and well-defined pore structures. The MZP nanoparticles serve as a porous coordination template that guides the controlled growth of HKUST-1 within a polymeric network, yielding a rigid selective layer with dual-micropores structure (0.44 and 0.68 nm) and high surface area (717.6 m 2 g -1 ). The resulting membrane exhibits exceptional methanol permeance (24.3 L·m -2 ·h -1 ·bar -1 ) and precise molecular sieving, achieving >98% rejection for solutes larger than 0.8 nm while allowing smaller molecules to pass quickly. In a representative pharmaceutical separation, the membrane demonstrates a high separation factor of 49.0 for vitamin B1/naringin, an 8.4-fold improvement over the pristine MZP membrane. Moreover, the membrane shows outstanding long-term stability (>200 h) and anti-fouling properties, and a scaled-up membrane (460 cm 2 ) successfully purifies naringin to 99.5% purity in a multistage process, outperforming commercial OSN benchmarks. This work provides a versatile and scalable platform to precisely engineer MOF-based membranes for high-precision molecular separations in the pharmaceutical and chemical industries.
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高影响因子
JOURNAL OF CHEMICAL THERMODYNAMICS
·
2016
·
IF 2.196
Peizhu Zheng,Dongxing Cai,Jihua Zhao,Weiguo Shen
The mixed surfactants of dodecyltrimethylammonium bromide (DTAB) and 1-dodecyl-3-methylimidazolium bromide (C 12 mimBr) in aqueous solutions were studied by measurement of electrical conductivity and isothermal titration microcalorimetry (ITC). The critical micelle concentrations (cmc) and the degree of dissociations of counter ions were determined for this system at various surfactant compositions, and the thermodynamic properties of micellization were evaluated. A one-parameter Margules equation was used to fit the cmc values to calculate the mole fraction, the activity coefficients of two surfactant components and the excess properties in mixed micelles.
研究领域:
胶体化学
·
物理化学
·
表面化学
·
热力学
·
溶液化学
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DOI
高影响因子
危险品化学品经营许可证（带存储）