JOURNAL OF POWER SOURCES
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2020
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IF 8.247
Wei Wu,Yuanyuan Kang,Man Wang,Dongwei Xu,Jun Wang,Yuliang Cao,Chaoyang Wang,Yonghong Deng
Constructing a stable microstructure is highly crucial in promoting the practical applications of Si-based negative electrodes , addressing the issues of huge volume change and unstable solid electrolyte interface (SEI). Herein, an integrated electrode structure is developed based on micro-sized SiO x particles by bilayers coating of carbon and poly(3,4-ethylene dioxythiophene) (PEDOT) with carbon nanotube/Super P conductive network in-situ embedded (SiO x @C@P_CS). The as-prepared SiO x @C@P_CS negative electrode exhibits high Coulombic efficiency reaching 99.9% and capacity retentions of 86.7% (1019 mAh g −1 ) after 1000 cycles at 750 mA g −1 and 98.4% (973 mAh g −1 ) after 400 cycles at 1500 mA g −1 (with a commercial-level areal capacity of 2.57 mAh cm −2 ). The excellent long cycling capability is further evidenced both in half cell with ultrahigh areal capacity up to 11.75 mAh cm −2 at the mass loading of 8.66 mg cm −2 and Li[Ni 0.8 Co 0.1 Mn 0.1 ]O 2 (NCM811)||SiO x @C@P_CS full cell with commercial loading. The improved electrochemical performance is attributed to the synergistic effects of the bilayers. This study offers a facile solution to the challenges facing alloying-type negative electrode materials with huge volume changes by confining volume change, enhancing electric conductivity , and isolating the growth of SEI to promote their practical uses.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2020
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IF 5.162
Ying Guan,Jun Rao,Yule Wu,Hui Gao,Shengquan Liu,Gegu Chen,Feng Peng
A renewable, efficient, and low-cost material is essential for adsorbing water pollution, such as dyes and heavy metal ions pollution. Here in, we demonstrate an aerogel to remove the dyes from water based on hemicellulose . The dialdehyde hemicelluloses (DAH) were synthesized by oxidation of hemicellulose extracted from straw with NaIO 4 . The hydrogels were prepared based on the dialdehyde hemicellulose and chitosan-Fe 3 O 4 composite by the Schiff's base reaction, which were processed with vacuum freeze-drying technique to obtain aerogels. It was found that hydroxyl groups at C 2 and C 3 of hemicellulose were oxidized to aldehyde groups after modification, and the content of aldehyde group was 5.57 mmol/g. The maximum compress strength of aerogel was 0.37 MPa, and the maximum absorption capacity of Congo red dye was 137.74 mg/g. Aerogels with Fe 3 O 4 exhibited magnetism which enables the aerogels to easily recycle. Meanwhile, the thermal stability , mechanical properties of the aerogels and its adsorption property to Congo red dye could be improved directly by the addition of Fe 3 O 4 .
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ACS Applied Materials & Interfaces
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2020
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IF 8.758
Ming Liu,Xun Zhu,Qiang Liao,Rong Chen,Dingding Ye,Gang Chen,Kun Wang
A catalytic membrane microreactor is a potential tool for the application in multiphase catalytic reactions. Currently, the installation of a permeable ultrathin membrane to separate the reactants with different phases and the grafting of a catalyst layer on the membrane in a microreactor remain challenging. In this work, a catalytic ultrathin membrane microreactor with an ultrathin freestanding supporting membrane was developed for nitrobenzene hydrogenation, which was formed by the interfacial polycondensation reaction with parallel laminar flow in a microchannel, followed by catalyst layer immobilization on one side of the ultrathin membrane surface using the layer-by-layer self-assembly technique and in situ reduction. The ultrathin freestanding membrane ensured a stable gas/liquid contact interface and good hydrogen permeability. The developed membrane microreactor could exhibit high catalytic performance under mild conditions, demonstrating its superior mass transport. In addition, the effects of the thickness of the ultrathin freestanding membrane, flow rates, and inlet nitrobenzene concentration were investigated to obtain the optimum operating conditions. The experimental results demonstrate that this newly developed membrane microreactor is a promising candidate for multiphase catalytic reactions.
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CERAMICS INTERNATIONAL
·
2020
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IF 3.83
Feng Xu,Hongge Yan,Jihua Chen,Zhengfu Zhang,Changling Fan
This work is focused on the mechanism study of nanoscale Co 3 O 4 powders prepared by an enhanced solid-state reaction method. The as-prepared powders are characterized by thermogravimetric-differential scanning calorimetry (TG-DSC), X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM) with the powders ball milled for different times as the control. The results show that ball milling can accelerate the thermal decomposition process by approximately 18.2%. Moreover, the apparent thermal decomposition activation energy of CoCO 3 powders pretreated by the enhanced solid-state method declined by 33.2%. To elucidate this,the thermal decomposition kinetic equations of CoCO 3 powders, with and without ball milling, are calculated. And the thermal decomposition kinetic equation of the ball-milled powders is d α /d t = (2.42E6~2.19E7) exp [(8.74E3~9.96E3)/ T ] 4/3(1- α ) [-ln(1- α )] 1/4 ; while that of the powders lack of ball milling is d α /d t = (1.08E10–1.07E11) exp [(1.43E4~1.51E4)/ T ] 2/3 α −1/2 , respectively. The reaction process at different time points can be forecasted by the obtained equations.
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Journal of Materials Chemistry B
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2020
·Vol. 8
·期 12
·2443-2453
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IF 5.344
Sihang Liu,Jun Ma,Liangbo Xu,Weifeng Lin,Weili Xue,Mei Huang,Shengfu Chen
Although zwitterionic hydrogels exhibit excellent hemocompatibility, their extremely low tensile strength is an obstacle for their use in blood-contacting devices. Electrospun fiber scaffold-reinforced zwitterionic hydrogels are a possible solution to overcome the challenges of both mechanical strength and hemocompatibility. In this work, electrospun polyurethane (ePU) fiber scaffold-reinforced sulfobetaine methacrylate (SBMA) hydrogels (SRgels) were prepared. The SRgels exhibited 4.7 ± 0.5 MPa tensile fracture stress, while the interpenetration between the hydrogel and the fiber scaffold remained intact even under 2.8 MPa tensile stress at 3.0 mm mm−1 strain load; this confirms that the SRgels maintain excellent hemocompatibility for both blood cell adhesion and fibrinogen adsorption under physiological dynamic loading and that dynamically structural matching is achieved between the scaffold and the zwitterionic hydrogels. Mechano-induced self-enhancement was also observed after preloading more than 2.0 mm mm−1 tensile strain to resist fracture. In short, the preparation of SRgels can enable zwitterionic hydrogels to meet the requirement for mechanical strength in bio-applications as blood-contacting devices.
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MACROMOLECULAR BIOSCIENCE
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2020
·Vol. 20
·期 9
·2000116
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IF 3.416
Jingjing Ye,Xindan Zhang,Wenqi Xie,Min Gong,Meihong Liao,Qinghan Meng,Jiajia Xue,Rui Shi,Liqun Zhang
Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) for relieving inflammatory reactions can lead to severe side effects. It is of great importance to configure new dosing strategies for alleviating the side effects of NSAIDs. In this work, an enzyme-responsive anti-inflammatory prodrug capable of generating indomethacin upon the trigger of inflammation is developed. A monomer is first prepared after the esterification of carboxyl groups of indomethacin by hydroxyl groups of N -(2-hydroxyethyl) acrylamide. Then, a polymer prodrug, with indomethacin linked through ester bonds on the side chain, is synthesized by free radical polymerization of the monomer. The therapeutic drug component can be triggered to release from the prodrug under the stimulation of cholesterol esterase, mimicking the inflammation environment. On the contrary, there is only a small amount of drug released in the absence of the enzyme. Therefore, the drug can be triggered to release under the stimulation of an environment mimicking inflammation. Furthermore, the in vitro studies at the cellular level indicate that the enzyme-responsive prodrug can efficiently relieve inflammatory responses induced by lipopolysaccharide in RAW264.7 macrophage cells while indicating no cytotoxicity.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2021
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IF 6.953
Min Zou,Jing-Yan Li,Meng-Jia Zhang,Jun-Hui Li,Jun-Tao Huang,Pei-Dan You,Shu-Wen Liu,Chun-Qiong Zhou
At present, there are still no anti-Zika virus (ZIKV) drugs or vaccines approved by FDA with accurate targets and antiviral mechanisms. Considering the RNA G-quadruplex sequences in ZIKV genome, it is very meaningful to develop G-quadruplex binders as potential anti-ZIKV drugs with novel and accurate targets. In this paper, five classical G-quadruplex binders including Ber , Braco 19 , NiL , 360A and PDS have been chosen to discuss their interaction with ZIKV RNA G-quadruplexes. PDS shows higher binding affinity and thermal stability than the other G-quadruplex binders. This property is further evidenced in cells by immunofluorescence microscopy. And PDS shows higher anti-ZIKV activity (EC 50 = 4.2 ± 0.4 μM) than the other G-quadruplex binders as well as the positive control ribavirin, with a low cytotoxicity. By time-of-addition assay, PDS exerts antiviral activity at the post-entry process of ZIKV replication cycle, thus inhibiting ZIKV mRNA replication and protein expression. Furthermore, PDS combines with ZIKV NS2B-NS3 protease and reduces its catalytic activity. This study suggests that G-quadruplex binder PDS is an effective multi-target ZIKV inhibitor, which provides more guidance to design some novel anti-ZIKV drugs targeting ZIKV RNA G-quadruplexes.
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HIGH PERFORMANCE POLYMERS
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2021
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IF 2.161
Oussama Mehelli,Mehdi Derradji,Abdelmalek Habes,Nour Elislem Leblalta,Raouf Belgacemi,Slimane Abdous,Yasmine Izri,Wenbin Liu
The design of lightweight neutrons shields has been restricted for quite some time to the use of the epoxy thermosets as the main building blocks. Meanwhile, the recent developments in the field of polymers suggest otherwise. Indeed, benzoxazine resins have taken the lead over the traditional thermosets in many exigent applications. Therefore, in a vision to introduce newer matrices with better performances and to further expand the applications of the benzoxazine resins into the nuclear field, the neutron shielding efficiency along with the thermal and thermomechanical performances of the neat benzoxazine polymer and its subsequent B4C-reinforced composites were investigated. The neutron shielding measurements were performed using an optimized experimental setup at NUR research reactor, Algiers. The neat benzoxazine polymer displayed almost similar thermal neutrons screening performances than the epoxy with a macroscopic cross-section (Σ) of a 0.724 cm−1 equivalent to a mean free path (λ) of 0.957 cm. The effect of the particle amount was also studied to maximize the shielding ability of the developed materials. For instance, the benzoxazine composite containing 20 wt.% of B4C displayed the outstanding screening ratio of about 96% for a sample thickness of 13 mm. Finally, the remarkable findings were put into context by providing multifaceted comparisons with the available shielding materials.
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MOLECULES
·
2021
·Vol. 26
·期 15
·4517
·
IF 4.412
Ye Tian,Qi Wang,Zhijian Peng,Shundong Guan,Xiuli Fu
A novel product consisting of a homogeneous tin oxide nanowall array with abundant oxygen deficiencies and partial Ni-Sn alloying onto a Ni foam substrate was successfully prepared using a facile solvothermal synthesis process with subsequent thermal treatment in a reductive atmosphere. Such a product could be directly used as integrated anodes for supercapacitors, which showed outstanding electrochemical properties with a maximum specific capacitance of 31.50 mAh·g−1at 0.1 A·g−1, as well as good cycling performance, with a 1.35-fold increase in capacitance after 10,000 cycles. An asymmetric supercapacitor composed of the obtained product as the anode and activated carbon as the cathode was shown to achieve a high potential window of 1.4 V. The excellent electrochemical performance of the obtained product is mainly ascribed to the hierarchical structure provided by the integrated, vertically grown nanowall array on 3D Ni foam, the existence of oxygen deficiency and the formation of Ni-Sn alloys in the nanostructures. This work provides a general strategy for preparing other high-performance metal oxide electrodes for electrochemical applications.Keywords:integrated anode;supercapacitor;nanowall array;oxygen-deficient tin oxide;Ni-Sn alloys
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SEPARATION AND PURIFICATION TECHNOLOGY
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2021
·
IF 7.312
Ying Quan,Qinfu Liu,Kuo Li,Hao Zhang,Liang Yuan
Due to the fine granularity of CG with the dissemination of non-graphite minerals, highly efficient purification of natural coaly graphite (CG) by low-cost, low-energy consumption and low-pollution methods remains a challenge. In this study, a novel and efficient electrochemical method is demonstrated for purifying natural CG. The electrochemical purification is carried out in a mixed electrolyte containing 0.5 M (NH 4 ) 2 SO 4 and 10% HF with an optimum potential sequence starting at + 2.5 V for a few minutes followed by a short burst of + 5 V. The CG purification mechanism is proposed based on the experimental results. There are three main factors, namely, the type of the graphite anode, the electrolyte and the applied voltage are critical for effectively electrochemical purification. It is interesting to find that the main purified products are graphene mixed with graphite aggregates at a yield of 68%. Raman analysis indicates that the purified CG has fewer structural defects than the natural CG after removing the non-graphite minerals. Moreover, the XPS and FTIR analysis demonstrate that no other functional groups are grafted onto the parent graphite during this purification process. In comparison with the electrolyte only containing HF, the adding of 0.5 M (NH 4 ) 2 SO 4 in the HF electrolyte could reduce the amount of HF by more than 50%, which cuts the cost and alleviates the impact on the environment.
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Horticulture Research
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2021
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IF 6.793
Dang Qingyuan,Sha Haiyun,Nie Jiyun,Wang Yongzhang,Yuan Yongbing,Jia Dongjie
Color is an important trait for horticultural crops. Carotenoids are one of the main pigments for coloration and have important implications for photosynthesis in plants and benefits for human health. Here, we identified an APETALA2 (AP2)/ETHYLENE RESPONSE FACTOR (ERF) transcription factor named MdAP2-34 in apple (Malus domestica Borkh.). MdAP2-34 expression exhibited a close correlation with carotenoid content in ‘Benin Shogun’ and ‘Yanfu 3’ fruit flesh. MdAP2-34 promotes carotenoid accumulation in MdAP2-34-OVX transgenic apple calli and fruits by participating in the carotenoid biosynthesis pathway. The major carotenoid contents of phytoene and β-carotene were much higher in overexpressing MdAP2-34 transgenic calli and fruit skin, yet the predominant compound of lutein showed no obvious difference, indicating that MdAP2-34 regulates phytoene and β-carotene accumulation but not lutein. MdPSY2-1 (phytoene synthase 2) is a major gene in the carotenoid biosynthesis pathway in apple fruit, and the MdPSY2-1 gene is directly bound and transcriptionally activated by MdAP2-34. In addition, overexpressing MdPSY2-1 in apple calli mainly increases phytoene and total carotenoid contents. Our findings will advance and extend our understanding of the complex molecular mechanisms of carotenoid biosynthesis in apple, and this research is valuable for accelerating the apple breeding process.
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ACS Chemical Neuroscience
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2021
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IF 4.418
Yishuai Yang,Yao Tan,Dongting Zhangsun,Xiaopeng Zhu,Sulan Luo
Nicotinic acetylcholine receptors (nAChRs) are essential pentameric ligand-gated ion channels that are distributed throughout the central and peripheral nervous systems and non-neuronal tissues in mammalian species that play critical roles in a variety of neural and mental activities. The α3β2 nAChR subtype participates in pain, addiction to nicotine, and other neurophysiological and pathological activities. Owing to the lack of highly selective pharmacological tools targeting α3β2, related research on its tissue distribution and function has been hindered. α-Conotoxin (α-CTx) LtIA, discovered from Conus literatus in our lab, potently and selectively blocks α3β2 nAChR, providing an important molecular probe to study the α3β2 nAChR structure and function. We used the fluorescent molecule 5-carboxytetramethylrhodamine succinimidyl ester, which can react with the N-terminus of LtIA, to obtain a novel fluorescent analogue of LtIA (LtIA-F). The potency and selectivity of LtIA-F were tested using a two-electrode voltage clamp recording on various nAChRs expressed in Xenopus laevis oocytes. LtIA-F potently inhibited ACh-evoked currents at the α3β2 nAChR, with an IC50 value of 90.66 nM, displaying a ∼4-fold decrease in potency compared with native LtIA without a change in selectivity. The serum stability results indicated that LtIA-F exhibited stability similar to that of native LtIA. This study on an α-CTx LtIA fluorescent analogue provides a wealth of pharmacological tools to explore the structure–function relationship, distribution, and ligand binding domain of the α3β2 nAChR subtype.
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