Biosensors-Basel
·
2023
·Vol. 13
·期 5
·506
·
IF 5.4
Yaofei Chen,Xin Xiong,Yu Chen,Lei Chen,Guishi Liu,Wei Xiao,Jifu Shi,Zhe Chen,Yunhan Luo
Surface plasmon resonance (SPR) based sensors play an important role in the biological and medical fields, and improving the sensitivity is a goal that has always been pursued. In this paper, a sensitivity enhancement scheme jointly employing MoS2nanoflower (MNF) and nanodiamond (ND) to co-engineer the plasmonic surface was proposed and demonstrated. The scheme could be easily implemented via physically depositing MNF and ND overlayers on the gold surface of an SPR chip, and the overlayer could be flexibly adjusted by controlling the deposition times, thus approaching the optimal performance. The bulk RI sensitivity was enhanced from 9682 to 12,219 nm/RIU under the optimal condition that successively deposited MNF and ND 1 and 2 times. The proposed scheme was proved in an IgG immunoassay, where the sensitivity was twice enhanced compared to the traditional bare gold surface. Characterization and simulation results revealed that the improvement arose from the enhanced sensing field and increased antibody loading via the deposited MNF and ND overlayer. At the same time, the versatile surface property of NDs allowed a specifically-functionalized sensor using the standard method compatible with a gold surface. Besides, the application for pseudorabies virus detection in serum solution was also demonstrated.Keywords:SPR-based biosensor;MoS2nanoflowers;Nanodiamonds;surface engineering;sensitivity enhancement
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MOLECULAR CRYSTALS AND LIQUID CRYSTALS
·
2023
·
IF 0.7
Chao Feng,Chang-Peng Lv,Jing-Jing Guo,Dong-Xu Li,Juan-Ni Zhang
The article discusses the synthesis and characterization of a new Cu-based complex, [Cu(Hpz)4SO4]]•[Cu(Hpz)4(H2O)SO4]•H2O (1), obtained via solvothermal method with the ligand 1H-pyrazole (Hpz). The complex exhibits a co-crystal structure composed of two independent units. The crystal structure was further confirmed by PXRD Rietveld refinement. In three-electrode system tests, the electrode made from this co-crystal complex displayed a high specific capacitance and a good cycling stability. At a scan rate of 3 mV s−1, the maximum specific capacitance was 242.4 F g−1, and after 2000 cycles at a current density of 2 A g−1 in a 1 M KOH solution, a capacitance of 95.5% was retained.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2023
·
IF 9.9
Qianqian Fu,Hui Wang,Kunlun Nie,Xuyun Wang,Jianwei Ren,Rongfang Wang
In the large-scale implementation of renewable energy devices, the availability of stable and highly catalytic non-precious metal catalysts for the hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) is crucial. Meanwhile, integrating bifunctional electrocatalysts simultaneously on both the anode and cathode still faces challenges. To address this, a stepped preparation strategy was adopted on a nickel foam (NF) substrate to synthesize P, S co-doped NiCoP x S y nanowire array catalysts. The prepared NiCoP x S y catalysts demonstrated a small Tafel slope of 72.5 mV dec −1 for HER and 72.3 mV dec −1 for OER by requiring only 37 mV (326 mV) overpotential to achieve a current density of 10 mA cm −2 (50 mA cm −2 ). Moreover, when assembled into an electrolytic cell in 1 M KOH, the NiCoP x S y catalysts achieved a low voltage of 1.55 V at 10 mA cm −2 current density and exhibited long-term stability. The outstanding electrocatalytic performance can be attributed to the influence of doped anions on the electronic states and distribution among different atoms, which thereby positively affected the electrocatalytic activity. This research provides an effective method for designing innovative catalysts and paving the way to produce clean energy.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHINESE JOURNAL OF CATALYSIS
·
2021
·
IF 8.271
Longfu Wei,Changlin Yu,Kai Yang,Qizhe Fan,Hongbing Ji
Currently, air pollution is being exacerbated by rapid social, economic, and industrial development. Major air pollutants include volatile organic compounds (VOCs) and CO. Photocatalytic and thermocatalytic technology can be used to convert VOCs and CO into harmless gases effectively. Recently, photothermal synergistic catalysis has aroused much attention because of its higher performance than those of individual photocatalytic and thermocatalytic processes. There have been many reviews on separate photocatalysts and thermocatalysts for the treatment of VOCs and CO, but few reviews have focused on photothermal synergistic catalysis. In this minireview, we concentrate on recent progress into photothermal synergistic catalysis for the efficient removal of VOCs and CO. The treatment of typical VOCs (such as benzene, toluene, ethanol, formaldehyde, acetone, propylene , and propane) and CO are summarized and analyzed. Furthermore, we discuss the use of conventional reactor technology, such as fixed-bed quartz reactors, for VOCs and CO removal. We also discuss the mechanism of the photothermal synergistic catalytic removal of VOCs and CO. Finally, we present perspectives for the photothermal synergistic catalytic removal of VOCs and CO.
✓ 已验证
产品关联
DOI
高影响因子
Advanced Composites and Hybrid Materials
·
2021
·Vol. 4
·期 1
·173-185
·
IF 5.693
Xie Peitao,Liu Yuan,Feng Mei,Niu Mang,Liu Chunzhao,Wu Nannan,Sui Kunyan,Patil Rahul Rangrao,Pan Duo,Guo Zhanhu,Fan Runhua
Carbon-based composites have gained extensive attention as microwave absorbing materials due to the lighter weight compared with other materials. In this work, Co/C nanocomposites with Co nanoparticles uniformly distributed in amorphous carbon sheets are prepared by a freezing dry and carbothermic reduction process. Hierarchical porous microstructures (micropores, mesopores, macropores) are achieved by ice template and huge amounts of gas during carbothermal reduction. Excellent absorption performance is achieved at a very low Co/C content (10% and 15%), which is a great success to design ultralight absorbers. At 10% content level, the effective absorption bandwidth is 5.0 GHz with a thin thickness of 1.8 mm, while the absorption bandwidth is 4.7 GHz with a thin thickness of 1.5 mm at 15% Co/C content level. The excellent absorption performance is attributed to excellent impedance matching resulting from synergy of cobalt and carbon and strong interfacial polarization induced by the hierarchical porous microstructures. This work provides a new pathway of designing ultralight absorbers with the advantage of thin thickness and wide bandwidth. Graphical Abstract
Excellent absorption performance is achieved at only 10% Co/C content level, a success to design ultralight absorbers.
✓ 已验证
产品关联
DOI
高影响因子
Advanced Science
·
2021
·Vol. 8
·期 8
·2003941
·
IF 16.806
Xian Sun,Xiaochuan Zhang,Xiaohong Ren,Hongyu Sun,Li Wu,Caifen Wang,Xiaohui Ye,Peter York,Zhaobing Gao,Hualiang Jiang,Jiwen Zhang,Xianzhen Yin
The effective pulmonary deposition of inhaled particulate carriers loaded with drugs is a prerequisite for therapeutic effects of drug delivery via inhalation route. Revealing the sophisticated lung scaffold and intrapulmonary distribution of particles at three-dimensional (3D), in-situ, and single-particle level remains a fundamental and critical challenge for dry powder inhalation in pre-clinical research. Here, taking advantage of the micro optical sectioning tomography system, the high-precision cross-scale visualization of entire lung anatomy is obtained. Then, co-localized lung-wide datasets of both cyto-architectures and fluorescent particles are collected at full scale with the resolution down to individual particles. The precise spatial distribution pattern reveals the region-specific distribution and structure-associated deposition of the inhalable particles in lungs, which is undetected by previous methods. Overall, this research delivers comprehensive and high-resolution 3D detection of pulmonary drug delivery vectors and provides a novel strategy to evaluate materials distribution for drug delivery.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ChemNanoMat
·
2021
·Vol. 7
·期 6
·635-640
·
IF 3.154
Chunfeng Cheng,Jiaqi Shao,Pengfei Wei,Yanpeng Song,Hefei Li,Dunfeng Gao,Guoxiong Wang
Graphical Nitrogen and boron co-doped carbon nanospheres shows an excellent catalytic performance for electrochemical CO 2 reduction reaction and achieves a CO Faradaic efficiency of 95.1% at a low overpotential of 310 mV. The electrochemical CO 2 reduction reaction (CO 2 RR) powered by renewable electricity is a promising route to close the carbon cycle, but it suffers from low product selectivity and high overpotential. Here we develop nitrogen and boron co-doped hollow carbon spheres (NB−CS) through the pyrolysis of a mixture comprising low-molecular-weight phenolic resols, melamine and boric acid. The optimized NB−CS catalyst presents high CO 2 RR performance and achieves a CO Faradaic efficiency of 95.1% at a low overpotential of 310 mV, superior to carbon spheres doped with nitrogen or boron alone. Structural and electrochemical characterizations indicate that the efficient CO 2 RR to CO over the NB−CS catalyst is likely ascribed to the unique graphitized architecture along with high conductivity, large surface area and high density of exposed N and B reactive sites. This work highlights opportunities to use cost-effective and readily available carbon nanomaterials as efficient CO 2 RR catalysts.
✓ 已验证
DOI
高影响因子
BIOMATERIALS
·
2021
·
IF 12.479
Jichun Yang,Shuojiong Pan,Shiqian Gao,Tianyu Li,Huaping Xu
Carbon monoxide (CO) therapy and antiangiogenesis therapy (AAT) are regarded as promising approaches for cancer treatment. However, the poor tumor targeting ability and inevitable side effects prevent their clinical application. In this study, we developed H 2 O 2 -responsive diselenide-containing micelles that combined CO therapy with chemosensitization therapy and AAT in a single system. Under the interaction of intratumoral H 2 O 2 , CO and gemcitabine (GEM) were released in situ from the micelles to reduce side effects, and CO significantly sensitized the chemotherapeutic effect of GEM by elevating the level of reactive oxygen species (ROS) in human gastric cancer AGS cells. Furthermore, diselenide bonds in the micelles were oxidized to seleninic acid in organic form, which suppressed the expressions of vascular endothelial growth factor (VEGF) and matrix metalloproteinase-2 (MMP-2) to realize AAT. This study provides an integrated solution to combine CO therapy with chemosensitization therapy and AAT together with good biocompatibility .
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Acta Biomaterialia
·
2021
·
IF 8.947
Wenjuan Huang,Sijie Zhou,Bojiao Tang,Hongyan Xu,Xiaoxiao Wu,Na Li,Xingjie Zan,Wujun Geng
Proteins play key roles in most biological processes , and protein dysfunction can cause various diseases. Over the past few decades, tremendous development has occurred in the protein therapeutic market due to the high specificity, low side effects, and low risk of proteins. Currently, all protein drugs on the market are based on extracellular targeting; more than 70% of intracellular targets remain un-druggable. Efficient delivery of cytosolic proteins is of significance for protein drugs, advanced biotechnology and molecular cell biology. Herein, we developed a co-assembly strategy for protein-hexahistidine-metal for intracellular protein delivery. Based on the coordinative interaction between His 6 and metal ions, various proteins were encapsulated in situ into nanosized and positively charged protein encapsulation particles( [email protected] ) through a co-assembly process with a high loading capacity and loading efficiency. [email protected] was able to deliver proteins with diverse physicochemical properties through multiple endocytosis pathways, and the protein could quickly escape from endosomes. In addition, the bioactivity of the loaded protein during co-assembly and the intracellular delivery processes were well preserved and could be properly exerted inside cells. Our results demonstrate that this strategy should be a valuable platform for protein delivery and has huge potential in protein-based theranostics. Statement of significance Intracellular targets with protein drugs may provide a new way for the treatment of many refractory disease. Herein, we developed a co-assembly strategy for protein-hexahistidine-metal for efficient intracellular protein delivery. Based on the coordinative interaction between His 6 and metal ions, various proteins were encapsulated in situ into nanosized and positively charged particles ( [email protected] ) with a high loading efficiency. [email protected] was able to deliver different proteins through multiple endocytosis pathways, and the protein could quickly escape from endosomes. In addition, the bioactivity of the loaded protein during co-assembly and the intracellular delivery processes were well preserved and could be properly exerted inside cells. This strategy should be a valuable platform for protein delivery and has huge potential in protein-based theranostics.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2021
·
IF 9.229
Caihong Fang,Xiaomin Jiang,Jinwu Hu,Jiaojiao Song,Na Sun,Deliang Zhang,Long Kuai
Ruthenium nanocrystals with small size and special morphology are of great interest in various catalytic reactions due to their high activities. However, it is still a great challenge to downsize these nanocatalysts to a sub-nano scale (<2 nm). Herein, we reported a synthesis of ultrasmall size and uniform Ru nanoparticles through a rapid one-pot method. The prepared Ru nanocrystal shows a wormlike shape, in which the diameter is as thin as 1.6 ± 0.3 nm and the length is 13.6 ± 4.4 nm. These Ru nanoworms (NWs) are quite steady during the synthetic process even though the reaction time was further prolonged. We also examined their catalytic activity toward CO oxidation by loading Ru NWs on TiO2 to form Ru NWs/TiO2 catalysts. These catalysts exhibit a high activity of 100% CO conversion at 150 °C, which is much lower than the normal Ru NPs/TiO2 nanostructures. Based on our detailed investigations, we proposed that the small size, special morphology, and TiO2 support are the keys for their significantly improved catalytic activity. We believed that these reasonable discoveries provide a methodology and opportunity to get highly active catalysts for CO oxidation by a detailed increase in their active sites.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2020
·
IF 3.99
Jiahui Deng,Yalin Cheng,Min Liu,Biyang Tu,Shan Xue,Haisheng Tao
In this study, Fe-Mn co-embed sodium alginate carbon spheres (Fe-Mn/SA-C) were prepared as a cost-effective adsorbent for aqueous Cd(II) removal by a facile pyrolysis method. The morphology and chemical composition of Fe-Mn/SA-C were explored with various characterized techniques. The results indicate that Fe-Mn/SA-C possess porous structures and abundant oxide-based functional groups. Fe-Mn/SA-C exhibits excellent adsorption properties for aqueous Cd(II) and the adsorption process is pH-dependent. The adsorption data could fit pseudo second-order and Langmuir models well, suggesting that chemisorption is a dominant adsorption mechanism and the maximum adsorption capacity is 280.11 mg −1 . Thermodynamic analysis demonstrates that the adsorption is spontaneous and endothermic. The adsorption mechanisms of Cd(II) include the complexation of Cd(II) with oxygen-based functional groups, precipitation, and ion exchange. Finally, the granulated and magnetic Fe-Mn/SA-C is an efficient and practical adsorbent for cadmium-containing wastewater treatment.
✓ 已验证
产品关联
DOI
高影响因子
Nature Communications
·
2020
·Vol. 11
·期 1
·1-7
·
IF 12.121
Tian Jinshu,Tan Jiangqiao,Zhang Zhaoxia,Han Peijie,Yin Min,Wan Shaolong,Lin Jingdong,Wang Shuai,Wang Yong
Direct oxidation of methane to value-added C 1 chemicals (e.g. HCHO and CO) provides a promising way to utilize natural gas sources under relatively mild conditions. Such conversions remain, however, a key selectivity challenge, resulting from the facile formation of undesired fully-oxidized CO 2 . Here we show that B 2 O 3 -based catalysts are selective in the direct conversion of methane to HCHO and CO (~94% selectivity with a HCHO/CO ratio of ~1 at 6% conversion) and highly stable (over 100 hour time-on-stream operation) conducted in a fixed-bed reactor (550 °C, 100 kPa, space velocity 4650 mL g cat −1 h −1 ). Combined catalyst characterization, kinetic studies, and isotopic labeling experiments unveil that molecular O 2 bonded to tri-coordinated BO 3 centers on B 2 O 3 surfaces acts as a judicious oxidant for methane activation with mitigated CO 2 formation, even at high O 2 /CH 4 ratios of the feed. These findings shed light on the great potential of designing innovative catalytic processes for the direct conversion of alkanes to fuels/chemicals.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）