INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
·
IF 7.7
Yaoxun Zeng,Jiongpeng Yuan,Zhili Ran,Xiaoguang Zhan,Xinyi Li,Huiling Ye,Jiapeng Dong,Guining Cao,Zhenxing Pan,Ying Bao,Junze Tang,Xujie Liu,Yan He
Surgical resection remains the primary treatment modality for bone tumors. However, it is prone to local bone defects and tumor recurrence. Therefore, there is an urgent need for multifunctional biomaterials that combine tumor treatment and bone repair after bone tumor surgery. Herein, a chitosan composite scaffold (CS/DOX@Ti-MOF) was designed for both tumor therapy and bone repair. Among them, the amino-functionalized Ti-based metal-organic framework (NH 2 -MIL-125 (Ti), Ti-MOF) has a high specific surface area of 1116 m 2 /g and excellent biocompatibility, and promotes osteogenic differentiation. The doxorubicin (DOX) loading capacity of Ti-MOF was 322 ± 21 mg/g, and DOX@Ti-MOF has perfect antitumor activity. Furthermore, the incorporation of DOX@Ti-MOF improved the physical and mechanical properties of the composite scaffolds, making the scaffold surface rough and favorable for cells to attach. CS/DOX@Ti-MOF retains the unique properties of each component. It responds to the release of DOX in the tumor microenvironment to remove residual tumor cells, followed by providing a site for cell attachment, proliferation, and differentiation. This promotes bone repair and achieves the sequential treatment of postoperative bone tumors. Overall, CS/DOX@Ti-MOF may be a promising substitute for postoperative bone tumor clearance and bone defect repair. It also provides a possible strategy for postoperative bone tumor treatment.
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高影响因子
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
·
2021
·Vol. 22
·期 19
·10412
·
IF 5.924
Huiping Chen,Yongpan Shan,Lidong Cao,Pengyue Zhao,Chong Cao,Fengmin Li,Qiliang Huang
Long-term use of a single fungicide increases the resistance risk and causes adverse effects on natural ecosystems. Controlled release formulations of dual fungicides with different modes of action can afford a new dimension for addressing the current issues. Based on adjustable aperture and superhigh surface area, metal–organic frameworks (MOFs) are ideal candidates as pesticide release carriers. This study used Al3+as the metal node and 2-aminoterephthalic acid as the organic chain to prepare aluminum-based metal–organic framework material (NH2-Al-MIL-101) with “cauliflower-like” structure and high surface area of 2359.0 m2/g. Fungicides of azoxystrobin (AZOX) and diniconazole (Dini) were simultaneously encapsulated into NH2-Al-MIL-101 with the loading content of 6.71% and 29.72%, respectively. Dual fungicide delivery system of AZOX@Dini@NH2-Al-MIL-101 demonstrated sustained and pH responsive release profiles. When the maximum cumulative release rate of AZOX and Dini both reached about 90%, the release time was 46 and 136 h, respectively. Furthermore, EC50values as well as the percentage of inhibition revealed that AZOX@Dini@NH2-Al-MIL-101 had enhanced germicidal efficacy against rice sheath blight (Rhizoctonia solani), evidenced by the synergistic ratio of 1.83. The present study demonstrates a potential application prospect in sustainable plant protection through co-delivery fungicides with MOFs as a platform.Keywords:NH2-Al-MIL-101;controlled release;dual encapsulation;synergistic effect;rice sheath blight
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Mengmeng Zhang,Qian Sun,Yuejiao Wang,Weijun Shan,Zhenning Lou,Ying Xiong
Reported powdery adsorbents with poor adsorption efficiency and stability make it imperative to develop novel materials to extract gallium ions (Ga(III)) from effluents. Herein, UiO-66-NH 2 -based mixed matrix membranes (TPU/0.1THB/U6N-1.5 MMMs) via electrospinning is firstly reported for separation and recovery of Ga(III). TPU/0.1THB/U6N-1.5 MMMs efficiently overcomes multiple bottlenecks of powder UiO-66-NH 2 , including poor stability, reusability and adsorption capacity. Its maximum adsorption for Ga(III) is 96.18 mg·g −1 at pH 10.0. It has superiority in selective adsorption of Ga(III) from Al(III), Cu(II), Zn(II), Co(II) coexistence solution. Adsorption capacity of TPU/0.1THB/U6N-1.5 for Ga(III) reaches more than 80% after 9 cycles. Specially, it still retains excellent mechanical strength, flexibility and structural integrity after 12 h filtration, or after 9 adsorption-desorption cycles, even soaked in 5 mol·L -1 HCl for a week. TPU/0.1THB/U6N-1.5 MMMs also improves the problem of low water flux. TPU/0.1THB/U6N-1.5 with high MOFs loading possess high water flux of 382.2 L·m −2 ·h −1 with a permance of 382.2 L·m −2 ·h −1 ·bar −1 and rejection rates of 90% for Ga(III). The main adsorption mechanism of TPU/0.1THB/U6N-1.5 is based on the chelation between phenolic hydroxyl groups of MMMs and Ga(III) at pH 10.0. Overall, the as-prepared TPU/0.1THB/U6N-1.5 has potential for water treatment through the process of membrane adsorption.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Zhou Zhou,Dongyun Chen,Najun Li,Qingfeng Xu,Hua Li,Jinghui He,Jianmei Lu
In order to fix the photocatalyst and enhance the efficiency of NO degradation, a three-dimensional (3D) g-C 3 N 4 /NH 2 -UiO-66-rGO (CN/NU6-rGO) aerogel was devised and fabricated via solvothermal reaction and boiling-water bath. Herein, a type-II heterojunction was formed at CN/NU6 composite, and then, the composite was coupled with rGO. The resulting material significantly enhanced the nitric oxide (NO, 600 ppb) removal efficiency under visible-light irradiation. Optimizing the content of CN and rGO to a suitable mass ratio can increase the removal efficiency by 65.4%, which is 2.34 times that of pure NU6. This result is attributed to the construction of type-II heterojunction and the charge transport properties of rGO. The involvement of rGO not only provided extra pathways for charge transfer to prevent electron–hole pairs from recombining, but also fixed the catalyst. Moreover, the hybrid aerogel excellently reduced the harmful by-product NO 2 . Cycling experiments, along with transient photocurrent response measurements, verified that CN/NU6-rGO had excellent potential for recyclable and sustainable. This work might shed light on the construction of suitable photocatalytic systems with significant improvement of NO removal and convenient storage of catalyst.
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高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2021
·
IF 8.742
Yixuan Gao,Siming Yan,Yi He,Yi Fan,Liyun Zhang,Jing Ma,Ruitong Hou,Li Chen,Jingyu Chen
Herein, a novel membrane with polyacrylic acid (PAA), NH 2 -MIL-88B(Fe) (NM88B), and graphene oxide (GO) was fabricated via a simple vacuum filter method equipped with the nylon membrane substrate. The composite membrane (PAA@NM88B/GO membrane) retained the laminated structure of GO, and PAA@NM88B was used as the photo-Fenton catalytic nano-filler to intercalate GO. Through a series of material characterization and membrane separation performance tests, the results showed that by introducing porous NM88B and PAA cross-linking modification, PAA@NM88B/GO membrane had excellent hydrophilicity, water flux and dye rejection performance. The flux of the PAA@NM88B/GO membrane was 68.21 L m −2 h −1 bar −1 , which is about 15 times higher than that of GO membrane. In addition, the composite membrane had a high rejection (over 97%) for methylene blue (MB), crystal violet (CV) and Congo red (CR). More importantly, PAA@NM88B/GO membrane can also be used to degrade textile wastewater in real life. The membrane can be used as a catalyst to degrade contaminants, and had a high removal of MB in 40 min (98.79%) under the synergistic effect of membrane adsorption and photocatalysis . Therefore, the results indicated that this new type of PAA@NM88B/GO membrane had potential applications in water purification and actual textile wastewater treatment .
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高影响因子
ANALYST
·
2020
·Vol. 145
·期 23
·7616-7622
·
IF 3.978
Jingxian Li,Xueling Shan,Ding Jiang,Yuru Wang,Wenchang Wang,Zhidong Chen
In this work, a solid-state electrochemiluminescence (ECL) sensor based on resonance energy transfer (RET) was proposed using MoS2QDs@g-C3N4 as a donor and NH2-SiO2@PTCA as an acceptor. Herein, MoS2QDs could significantly facilitate the stability and efficiency of the ECL of g-C3N4. PTCA provided a large platform to anchor NH2-SiO2 nanoparticles. The prepared MoS2QDs@g-C3N4 exhibited good spectral overlap with the UV–vis absorption spectrum of NH2-SiO2@PTCA. Based on this, we designed an “off–on” ECL sensing strategy for sensitive and selective detection of glutathione (GSH). Under the best conditions, the linear range of the sensor for GSH detection was from 0.001 to 100 μM with a detection limit of 0.63 nM (S/N = 3). More importantly, GSH in commercial samples can be detected using the proposed sensor, which indicated its superior detection capabilities and potential application value in commercial medicines.
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高影响因子
Inorganic Chemistry Frontiers
·
2020
·Vol. 7
·期 19
·3636-3645
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IF 5.958
Yifei Ye,Dazhi Li,Ping Xu,Jianmin Sun
Until recently, many metal-based catalysts have been developed for the cycloaddition reaction of CO2 with epoxides. However, the leaching of the active metal component would lead to various environmental problems. A novel nonmetal B-doped Lewis acid–base catalyst with hydrogen bond donor (HBD) groups (B-SBA-15-NH2) was prepared successfully through the hydrothermal process and post-modification. B-SBA-15-NH2 exhibited good catalytic performance for the CO2 cycloaddition reaction, and 95% yield of propylene carbonate and satisfied selectivity (98%) were achieved in the presence of the KI cocatalyst. The efficient catalytic activity of B-SBA-15-NH2 resulted from the synergistic effects of B and HBD groups, together with the functionalized –NH2 groups. B-SBA-15-NH2 also exhibited good generality with acceptable yields for the corresponding cyclic carbonates in the CO2 cycloaddition with various epoxides. Furthermore, the developed B-SBA-15-NH2 catalyst could be easily separated by centrifugation and reused for five runs without an obvious loss in activity. The good activity and stable reusability of the metal-free B-SBA-15-NH2 catalyst demonstrate that it is a promising green candidate catalyst in the field of CO2 conversion.
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高影响因子
JOURNAL OF MATERIALS SCIENCE
·
2020
·Vol. 55
·期 26
·12041-12052
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IF 3.553
Yi Xuerui,He Xiaobo,Yin Fengxiang,Yang Tong,Chen Biaohua,Li Guoru
The global NH 3 production is dominated by Haber–Bosch process, requiring high temperature and pressure. Electrochemical N 2 reduction reaction (NRR) under ambient conditions is a greener path for artificial N 2 fixation to NH 3 but calling for efficient catalyst to increase activity and selectivity. Herein, we report the iron-based metal–organic frameworks (MOFs), i.e., MIL-88B–Fe and amine-functionalized MIL-88B–Fe (NH 2 –MIL-88B–Fe) as efficient catalysts for electrochemical NRR under ambient temperature and pressure in neutral electrolyte. NH 2 –MIL-88B–Fe shows higher NH 3 yield rate of 1.205 × 10 –10 mol s −1 cm −2 than MIL-88B–Fe (3.575 × 10 –11 mol s −1 cm −2 ). Furthermore, NH 2 –MIL-88B–Fe exhibits the highest Faradaic efficiency of 12.45% at 0.05 V versus RHE. The control experiments prove that NH 3 is produced through electrocatalytic NRR. This work may trigger the interest of using MOFs as highly efficient catalysts for electrochemical NH 3 production.
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高影响因子
ELECTROANALYSIS
·
2019
·Vol. 32
·期 3
·462-469
·
IF 2.691
Xiaomeng Shan,Tao Pan,Yuting Pan,Wenchang Wang,Xiaohui Chen,Xueling Shan,Zhidong Chen
In this study, a novel electrochemiluminescence (ECL) sensor for highly sensitive and selective detection of Pb(II) was developed based on Ru(bpy) 3 2+ encapsulated UiO66 metal-organic-framework (Ru(bpy) 3 2+ −UiO66 MOF) and −NH 2 group functionalized silica (NH 2 −SiO 2 ). The NH 2 −SiO 2 with large surface area provided an excellent platform for the ECL sensor. As numerous exposed carboxyl groups were present on UiO66 backbone, the Ru(bpy) 3 2+ −UiO66 could be steadily immobilized to NH 2 −SiO 2 by forming amide bonds. Meanwhile, the introduced UiO66 MOF which used for the encapsulation of Ru(bpy) 3 2+ , significantly enhanced the ECL efficiency of the proposed sensor, as it possessed a large specific surface area and porosity for the loading of Ru(bpy) 3 2+ . Moreover, a high quenching effect on ECL intensity was obtained in the presence of Pb(II) in the electrolyte. Under the optimal conditions, the quenched ECL intensity showed a good linear relationship within Pb(II) concentration in the range from 1.0×10 −6 to 1.0×10 2 μM, with a detection limit of 1.0×10 −7 μM ( S / N =3). The proposed sensor for Pb(II) detection was simple in operation, rapid in testing, stable in signal, and showed a good anti-interference ability to some other metal ions. Besides, its application for detecting Pb(II) in a real sample was also investigated here. This work provides a potential platform for metal ions detection in environmental monitoring field.
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高影响因子
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
·
2019
·Vol. 166
·期 12
·B873
·
IF 3.12
Xiaoyu Zhao,Wenlong Bai,Yujia Yan,Yanfei Wang,Juankun Zhang
Cadmium ions have variable degrees of toxicity on the environment and organisms. An electrochemical sensor based on self-doped polyaniline (SPAN) modified Metal-organic Framework (SPAN@UIO-66-NH2) with high electron mobility was developed. Cyclic voltammetry and electrochemical impedance spectroscopy indicated that doping of SPAN enhanced the electron transfer rate of UIO-66-NH2 in SPAN@UIO-66-NH2. The optimized Cd2+ sensor exhibited good linear response from 0.5 μg L−1 to 100 μg L−1, low detection limit of 0.17 μg L−1 (based on S/N = 3), good stability, and fast response time. It showed decent reliability for detection of trace Cd2+ in natural lake and urine samples.
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高影响因子
ENZYME AND MICROBIAL TECHNOLOGY
·
2019
·
IF 3.553
Xuejia Shi,Jin Xu,Changning Lu,Zhenzhong Wang,Wei Xiao,Linguo Zhao
The magnetic particle Fe 3 O 4 -SiO 2 -NH 2 -Cellu-ZIF8 (FSNCZ8) was used to immobilize the high-temperature resistant GH3 β-glucosidase (Tpebgl3) from the Thermomotoga petrophila DSM 13995. The Tpebgl3 has great potential in the catalytic conversion of pharmaceutically active components. The magnetic carrier (FSNCZ8) which provided stronger adsorption capacity, magnetic and high-temperature stability than the previously discussed Fe 3 O 4 -NH 2 -Cellu-ZIF8 without tetraethyl silicate coated. The properties of FSNCZ8-Tpebgl3 (FSNCZ8-T) were as follows: The optimal temperature and pH were 90 °C and 5.5, respectively; the highest activity of FSNCZ8-T approached 2672 U/g; Fe 2+ enabled immobilized enzyme to increase its relative activity to 194%. The main characteristics of FSNCZ8-T, including thermal stability, pH stability, and glucose tolerance, were greatly enhanced by adding Fe 2+ , which was also superior to free enzymes; moreover, the residual activity of FSNCZ8-T was 74% of the initial activity at the end of 10 repeated cycles.
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高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2018
·Vol. 135
·期 46
·46759
·
IF 1.901
Mingmin Jia,Yi Feng,Jianhao Qiu,Xiaocheng Lin,Jianfeng Yao
UiO-66-NH 2 nanocrystals were synthesized and embedded into bromomethylated poly(phenylene oxide)/polyethersulfone (BPPO/PES) polymer matrix to form UiO-66-NH 2 /BPPO/PES mixed matrix membranes (MMMs). The crystalline structure, interaction between UiO-66-NH 2 and BPPO, and dispersion of UiO-66-NH 2 were characterized by FTIR, XRD, and SEM. Nanoparticle dispersion was drastically enhanced with the assistance of BPPO, giving an improved adhesion between the polymer and filler particles. Owing to the intrinsic adsorption property of UiO-66-NH 2 and BPPO to CO 2 , the CO 2 permeability was significantly increased. As a result, the UiO-66-NH 2 /BPPO/PES membrane exhibited enhanced gas separation performance, where CO 2 /N 2 and H 2 /N 2 ideal selectivities were increased to 50.2 and 302.4 with a CO 2 permeability of 125.6 Barrer. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018 , 135 , 46759.
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高影响因子
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