INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2024
·
IF 7.7
Feng Gu,Wenjing Yang,Guoqing Xiao,Haoran Wang,Quan Yang,Zhaosheng Cai,Wangxia Wang,J.Y. Zhu
Improving flame retardancy and mechanical strength of lignin-containing polyurethane is a great challenge. In this study, lignin with favorable reactivity and dispersity was extracted from poplar using acid hydrotrope p -TsOH in EtOH. The extracted acid hydrotrope lignin (AHL) was subsequently functionalized with nitrogen and phosphorus (FHL) and reacted with isocyanate to fabricate a fire-retardant polyurethane (FHL-PU). The resulting FHL-PU exhibited a five-fold increase in fracture toughness and remarkable reprocessability, attributable to the dual cross-linked network formed by dynamic hydrogen bonds and carbamate bonds between AHL and PU. Furthermore, the FHL can effectively prevent the release of heat and smoke through mechanisms like forming a char layer at elevated temperatures, generating non-combustible gases and sequestering free radicals. As a result, the FHL led to a reduction in the peak heat release rate and total heat release of PU from 946.8 kW/m 2 and 86.9 MJ/m 2 to 383.5 kW/m 2 and 28.4 MJ/m 2 , respectively. This acid hydrotrope lignin modified polyurethane, holds tremendous potential for a wide range of practical applications.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Ye Zhang,Yutong Wen,Yingying Li,Zhiqi Li,Zhen Wang,Bing Fan,Qiaoyu Li,Wanchen Cai,Ying Li
The infections triggered by bacteria often cause wound deterioration, and the development of safe and effective antimicrobial treatment is always highly desired. In this paper, naturally derived lignin was aminated to generate surface group functionalized lignin nanoparticles (NPs), efficiently loading Ag NPs and adsorbing L-arginine, to construct lignin-based nanoenzyme (SALL), which achieves synergistic antimicrobial treatment by chemodynamic therapy and NO gas therapy, while the dose of silver was decreased. The SALL is dispersed in eco-friendly hydrogel constructed using keratin and chitosan through realigned disulfide bond and diverse intermolecular interactions, the prepared SALL@K/C hydrogel has ideal rheological property, and strong adhesion capacity facilitating active bacteria capture, ensuring that the bacteria were immobilized within the effective range of reactive oxygen species and NO. The inhibition rates of S. aureus and E. coli were 98.5 % and 97.8 %, respectively. Meanwhile, the SALL@K/C hydrogel could achieve the delivery of hydrophobic drug curcumin for inhibiting inflammation. The study highlights a well-designed nanoenzyme-loaded hydrogel with excellent antibacterial, hemostatic, and antiinflammatory properties, offering new ideas for nanoenzyme design and antimicrobial hydrogel development.
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ADVANCED FUNCTIONAL MATERIALS
·
2024
·
IF 18.5
Xuan Liu,Hui Jie Zhang,Shuangshuang Xi,Yifan Zhang,Ping Rao,Xiangyu You,Shaoxing Qu
Hydrogel coatings are crucial strategies for integrating substrates with functional surfaces. Hydrogel coating with a facile coating process, high toughness, and ultrathin thickness is highly desired. This study utilizes the self-assembly of hydrophobic lignin into chain-dense regions during solvent evaporation and constructed a hydrogel coating with Janus structure from hydrophilic polymer and hydrophobic lignin through a facile coating-drying-swelling process at room temperature (25 °C). The Janus structure formed as the hydrophobic lignin-aggregated regions remained at the bottom while the hydrophilic polymer swell at the top. The lignin-aggregated regions constrained the swelling of the hydrogel coating, allowing for an ultrathin coating layer of ≈8 µm. Additionally, the lignin-aggregated region increases the stiffness and toughness of the thin hydrogel coating film by establishing strong interfacial bonding with the substrate via dense Van der Waals forces, thereby increasing overall adhesion energy with thin thickness and to various substrates such as glass, polytetrafluoroethylene (PTFE), metal, and rubber. The hydration layer is formed by the hydrophilic polymer swollen on top, which improves lubrication and antifouling properties. Furthermore, the hydrogel coating exhibits high stability in water and saline solutions, ultraviolet shielding properties, and the ability to be removed and recycled after use.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Deyan Du,Tatsuo Kaneko,Weifu Dong,Mingqing Chen,Dongjian Shi
Intrinsic environmental instability of hydrogels has limited their practical applications as durable flexible sensors in human life. In this study, a bio-based eutectogel (BEG) with environmental tolerance was designed via deep eutectic solvent (DES), thioctic acid (TA) and lignin. Benefit from self-ring-opening polymerization of TA monomer in the ethanol and the lignin acting as free radicals, the BEG was fabricated through efficient cast-drying method. The dynamic interaction formation between DES and TA polymer network was revealed by using in-situ infrared spectroscopy during the ethanol evaporation process. The introduction of lignin not only improve the mechanical properties of the eutectogels, but also endow the BEG with moisture tolerance by activating self-aggregated dense hydrophobic layer on the surface while in high humidity environment. This bio-based eutectogels with non-volatility, board range operating temperature and proper self-adhesion could serve as long-term stable temperature-strain dual sensor with high sensitivity (GF = 1.17, TCR = 4.26 %/K) and rapid response behavior (373 ms). Furthermore, the biocompatible BEG was validated for recording human physiological signals over extended period with performance comparable to commercial hydrogel electrodes. This strategy could broaden the range of making durable stretchable eutectogels in human healthcare monitoring.
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INDUSTRIAL CROPS AND PRODUCTS
·
2025
·
IF 6.2
Xingjie Guo,Qianqian Chen,Dingfu Wang,Pan Liu,Yingdong Zhou,Zhicheng Jiang,Bi Shi
Taking advantages of the structural features of lignin for its functionalization application benefits to develop a sustainable lignin biorefinery process. Herein, cage-like hollow carbon sphere (LC) with high stability and reducibility was fabricated by spray drying and controlled carbonization, due to the high content of carbon element and abundant phenolic hydroxyl groups of lignin. Spray drying would induce the self-assembly of lignin during solvent evaporation, and the introduction of KOH in this process increased the specific surface area of LC and created more surface defects. The controlled carbonization led to the cross-linking of lignin and partly retained the lignin polyphenolic structure, which could be used to adsorb and in situ reduce Pd 2 + to prepare Pd/LC catalyst. Owing to the synergistic catalytic effect of the abundant defect sites on the LC surface and the active Pd sites, the Pd/LC catalyst could catalyze the hydrodeoxygenation of vanillin to 2-methoxy-4-methylphenol under mild reaction conditions (90 °C, 1.5 h, 0.5 MPa H 2 ). Besides, the catalyst showed high activity after four cycles and universality for the other lignin-derived aromatic aldehydes.
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CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Yang Wang,Qiaoling Liu,Chuanyu Yan,Guoyong Song,William S. Price,Gang Zheng,Allan M. Torres,Zhimin Xue
High-value utilization of lignocellulose and its components is generally constrained by the pretreatment efficiency and the structural robustness of fractionated components. Harsh pretreatment conditions can promote pretreatment efficiency but also cause serious condensation of lignin structure, thus inhibiting the depolymerization of lignin into valuable chemicals. Herein, we designed a novel deep eutectic solvent (DES) composed of pyridine hydrochloride, ethylene glycol, and AlCl 3 for the pretreatment of lignocellulose. In the developed DES, the lignocellulose could be efficiently fractionated into the natural lignin derivatives with satisfactory hydrogenolysis reactivity and the carbohydrate fraction with high enzymatic digestibility owing to the synthesized DES having adjustable hydrogen-bond acidity, high affinity for lignin, and good protection role on lignin structure. After being pretreated under a mild fractionation condition (70°C, 6 h), a promising delignification ratio of 70.4 % was obtained for poplar, and the extracted lignin exhibited native substructure with well-preserved β-O-4 linkages (42.1 per 100 aromatic units), abundant hydroxyl groups content (4.97 mmol/g), and high molecular weight (5643 g/mol). These structural features contributed to the conversion of the obtained lignin into aromatic monomers with a high yield (27.4 %). Besides, the pretreated residue could be efficiently converted into glucose with a yield of 88.2 % due to the abundant hydroxyl groups of lignin in the cellulose-rich residues. Remarkably, comprehensive studies of lignin structural evolution during pretreatment revealed that the structure-controllable lignin could be effectively isolated by modulating the hydrogen-bond acidity of DESs. This work proposed a mild and efficient lignin-first biorefinery approach that was conducive to the integrated valorization of lignocellulose.
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CARBOHYDRATE POLYMERS
·
2024
·
IF 10.7
Tongjun Yang,Rongli Li,Mingtao Ding,Hong Yu,Lihua Zhang,Haibo Xie
Chitin nanocrystals (ChNCs), prepared from a down-sizing process from chitin, have recently captured great attention to access sustainable nanomaterials. The surface modification of ChNCs is crucial to regulate the surface physicochemical properties and introduce specific functions, thus satisfying their diverse applications. In this study, aldehyde-functionalized ChNCs (ChNCs-PVMA) with enhanced hydrophobicity were developed via surface-initiated activators regenerated by electron transfer for atom transfer radical polymerization (SI-ARGET ATRP) of a lignin-derived polymerizable aldehyde monomer, vanillin methacrylate (VMA). The monomer conversion was determined by 1 H NMR spectroscopy of the reaction mixture based on the change of the relative ratio of VMA and solvent signals. The prepared ChNCs-PVMA were systematically characterized by FTIR, CP/MAS 13 C NMR, XPS, XRD, DSC, TGA, and TEM. The dispersibility of ChNCs and ChNCs-PVMA in water and DMF was evaluated by dynamic light scattering and visual observation, indicating good dispersion of ChNCs-PVMA in organic solvents. Furthermore, based on the available aldehyde groups, the ChNCs-PVMA was reacted with amino acids via Schiff base reaction, demonstrating a rich follow-up chemistry towards diverse functions by the reactive aldehyde groups.
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CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Xueqing Hu,Xiao Ma,Chunyu Chang,Bo Duan
Exploring green and sustainable alternative materials to address the growing environmental issue caused by petroleum-based plastics has led to increasing attention for the development of degradable bio-based plastics. The synthesis of bioplastics with high strength and toughness still faces a big challenge. Herein, we report a full noncovalent mediated self-assembly strategy for simultaneously improving the strength and toughness of chitin-based bioplastics via plane hot-pressing. The alkali lignin (AL) is introduced to enhance the strength and toughness of the chitinous bioplastics via forming multiple noncovalent interactions with chitin chains. The incorporated dense noncovalent networks and the pressure induced orientated nanofibers significantly enhanced the mechanical properties of the chitinous bioplastic, achieving a tensile strength of 159.0 ± 2.1 MPa and Young’s modulus of 8.4 ± 0.2 GPa at 58 % relative humidity. The alkali lignin improved the moisture stability of the chitinous bioplastic. Moreover, the chitinous bioplastics exhibited superior welding ability, solvent resistance, good UV shielding capability and biodegradability in nature, which demonstrates the developed fabrication design of chitinous bioplastics provides a promising concept for preparing the alternative materials to replace traditional plastics.
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JOURNAL OF BIOTECHNOLOGY
·
2024
·
IF 4.1
Chunyang Yu,Zekang Wang,Xiangjin Fu,Chun Liu,Anping Li,Qinlu Lin,Tianqing Lan,Xinshu Zhuang
Lignin can affect the enzymatic hydrolysis efficiency of lignocellulose. In this study, the lignin isolated from sugarcane bagasse (SCB) pretreated with p-toluenesulfonic acid (PL) was firstly aminated, and then the effects of PL and aminated PL (APL) on the bagasse enzymatic hydrolysis efficiency (EHE) were investigated. The results showed that the addition of PL and APL promoted the EHE, and EHE with APL (73.82 %) was higher than PL (51.39 %). To explore the reason, the data were further analyzed including cellulase adsorption capacity, enzyme activity, cellulase-lignin interaction, and molecular docking. It was found that APL adsorbed more cellulase (27.83 mg protein/g lignin) than PL (4.96 mg protein/g lignin), resulting from the greater interaction force and lower binding free energy between APL and cellulase. The addition of APL more remarkably enhanced the cellobiohydrolase and endoglucanase activities than PL due to more effectively inducing cellulase conformation optimization.
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Fermentation-Basel
·
2024
·Vol. 10
·期 5
·247
·
IF 3.3
Jinxun Lei,Zhihong Xu,Yong Chen,Guo Yu,Zexiang Liu,Shuangfei Wang,Jian Zhang,Kelin Li,Li Xie
The lignin derivatives generated during pulping might be responsible for the suboptimal performance of anaerobic reactors during the treatment of pulping wastewater. However, the exact mechanisms by which these derivatives exert influence remain unclear. This study investigated the influence of lignin derivatives, simulated using humic acids (HAs), in anaerobic granular sludge (AnGS). Compared to the enzymes present during floc-bonding and granule-bonding, the HAs impeded the conversion of unhydrolyzed substrates into methane and caused considerable inactivation of free enzymes. Simultaneously, the HAs suppressed agglomeration and weakened the strength of the AnGS. Furthermore, calcium ions helped maintain the integrity of the sludge structure. Therefore, the inhibition of extracellular enzymes using lignin derivatives delays the methanation of unhydrolyzed substrates, resulting in a reduced biomass within AnGS reactors owing to sludge disintegration and biomass loss. This study serves as a reference for investigating the persistent risks originating from lignin derivatives associated with using anaerobic granular-sludge bed reactors to treat pulping wastewater.
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RARE METALS
·
2025
·Vol. 44
·期 2
·889-900
·
IF 11
Feng Ping-Xian,Chen Qi-Liang,Yang Dong-Jie,Wang Huan
Developing high-capacity carbon-based anode materials is crucial for enhancing the performance of lithium-ion batteries (LIBs). In this study, we presented a nitrogen-doped lignin mesoporous carbon/nickel/nickel oxide (NHMC/Ni/NiO) nanocomposite for developing high-capacity LIBs anode materials through carbonization and selective etching strategies. The synthesized NMHC/Ni/NiO-0.33 composite exhibited a highly regular microstructure with well-dispersed Ni/NiO particles. The composite had a surface area of 408 m 2 ⋅g −1 , a mesopore ratio of 75.0%, and a pyridine–nitrogen ratio of 58.9%. The introduction of nitrogen atoms reduced the disordered structure of lignin mesoporous carbon and enhanced its electrical conductivity, thus improving the lithium storage capabilities of the composite. Following 100 cycles at a current density of 0.2 A⋅g −1 , the composite demonstrated enhanced Coulomb efficiency and rate performance, achieving a specific discharge capacity of 1230.9 mAh⋅g −1 . At a high-current density of 1 A⋅g −1 , the composite exhibited an excellent specific discharge capacity of 714.6 mAh⋅g −1 . This study presents an innovative method for synthesizing high-performance anode materials of LIBs. Graphical abstract
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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2024
·
IF 5.7
Hanhan Xie,Ji Yang,Tong Liu,Xinyue Zhang,Shan Zuo,Yingjie Gao,Xi Kuang,Tao Zhang
Lignin is dietary fiber from plant cell walls with multiple biological antioxidant and anti-inflammatory activities. However, whether lignin protects from ulcerative colitis (UC) and underlying mechanisms is unclear. Herein, UC mouse modeling was established with dextran sulfate sodium (DSS) and treatment with lignin for 1 week. Results showed that lignin inhibited the disease activity index (DAI), histological damage, and cell death in UC mice. We also found that lignin reversed the alterations of ferroptotic features in DSS-induced mice and ferroptotic cells, as evidenced by increased expression of GPX4 and 4-HNE and decreased transferrin expression, ameliorating the phenomenon of iron overload, GSH depletion, and ROS and MDA production. Furthermore, the increased expression of NRF2 was observed in IECs under lignin treatment. Also, the upstream regulatory molecule ERK of NRF2 was activated. Further research revealed that lignin can bind GPR37. Meanwhile, lignin was able to alleviate colitis by improving the composition of the intestinal flora in DSS mice and its effect was similar to that of 5-ASA. Taken together, these findings suggest that lignin protects against ferroptosis in UC by combining GPR37 and activating the ERK-NRF2-GPX4 signaling axis, which provides new ideas for clinical intervention in the treatment of UC.
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