FOOD HYDROCOLLOIDS
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2024
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IF 11
Tiantian Liu,Jiayi Xue,Ruoran Qin,Longwei Jiang
This study used chitosan (CS) as the film matrix and curcumin (Cur) as the indicator (CC). Inspired by the adhesion of mussels, a hydrophobic indicator film was prepared by fixing a hydrophobic layer formed by rice bran wax (RW) and hydrophobic SiO 2 onto the CS matrix via dopamine self-polymerization. The results showed that the CS film with RW and SiO 2 coatings (CC-R-S) presented hierarchical micro- and nanostructures, significantly increasing the hydrophobicity and stability compared with those of CC. The water contact angle (WCA) increased from 84.28° to 130.43°. Even after mechanical abrasion, the WCA remained above 118°, and after chemical corrosion, the WCA stabilized at approximately 120°. The excellent durability enabled CC-R-S films to be applicable to the internal surfaces of various food packages to decrease the amount of liquid food remaining as much as possible. Moreover, after being sprayed with RW-SiO 2 , the elongation at break increased by 1.73 times, whereas the water vapor permeability decreased by 0.19 times. The CC-R-S film also displayed good pH responsiveness and NH 3 sensitivity. When monitoring the freshness and preservation of pork at different temperatures, the CC-R-S film clearly varied in color from yellow to red but also extended the shelf life of pork by 2 days at 25 °C and 4 °C. Therefore, this study holds enormous potential for the application of smart food packaging to monitor meat quality changes.
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INTERNATIONAL JOURNAL OF PHARMACEUTICS
·
2012
·
IF 3.35
Ruifen Xu,Shangjing Xin,Xue Zhou,Wei Li,Feng Cao,Xuyang Feng,Hongbing Deng
Organic rectorite (OREC) was added in the quaternized chitosan (QC)/alginate (ALG) nanoparticles using an ionic gelation method to fabricate a controllable release system for proteins for the first time. The morphology of nanoparticles, the intercalated structure of OREC, bovine serum albumin encapsulation efficiency and in vitro release properties were investigated. Fourier transform infrared spectra, energy dispersive X-ray, X-ray photoelectron spectroscopy, small angle X-ray diffraction and size distribution analysis were performed to characterize the composite nanoparticles. With the addition of OREC, the encapsulation efficiency and the loading capacity of nanoparticles had increased from 21.2% to 44.9% and from 13.7% to 25.0%, respectively. In addition, the rapid initial release was inhibited successfully from 20.15% to 11.07% in stimulated gastric fluid and from 14.69% to 4.52% in stimulated intestinal fluid. The results verified that the addition of OREC could make these nanoparticles effective carriers to encapsulate drug and slow the drug controlled release of nanoparticles.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Yumeng Gao,Jing Wu,Jian Shen,Yan Xu,Lu Li,Wentao Wang,Ninglin Zhou,Ming Zhang
Getting rid of the biofilms is a major challenge when treating skin and soft tissue infections (SSTI), an inflammatory illness brought on by bacteria. Traditional magnetic materials have a limited dispersibility and a biofilm permeable property, making it challenging to remove biofilms and causing infection to linger. To solve these problems, we developed a kind of magnetic composite nanoplatform coated with indocyanine green carbon dots and modified with chitosan modification (Fe-ICGCDs@CS). Fe-ICGCDs@CS has high dispersibility and improves the conductivity of biofilms under magnetic action. Fe-ICGCDs@CS can adsorb bacteria via the positive charge and achieve precise photothermal sterilization and photodynamic therapy (PDT). Moreover, by catalyzing hydrogen peroxide (2 mM), Fe-ICGCDs@CS can produce oxygen to relieve the anoxic state in the deep layer of biofilms and activate dormant bacteria to make them sensitive to external stimuli. All in all, unlike the common “just kill” sterilization model, Fe-ICGCDs@CS can accurately kill bacteria and be recovered by an external magnetic field at the end of treatment, thus reducing the potential biological toxicity of nanomaterials. Therefore, the proposed Fe-ICGCDs@CS provides a new antibacterial method with low biotoxicity for clinical application in the treatment of biofilm infections.
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ACS Applied Electronic Materials
·
2024
·
IF 4.3
Shengyang Zhou,Hongjian Zhang,Changzhou Du,Ming Liu,Liming Liu,Yong Zhang
Polymer-based piezoelectric composites have shown a large potential in various fields of wearable electronics, man–machine interaction, transducers, etc., due to their integrated advantages of high piezoelectric properties, benign flexibility, and pressure sensitivity. As the representative polymer matrix in piezoelectric composites, polyvinylidene fluoride (PVDF) is characterized by its intrinsic piezoelectric response induced via the existence of ferroelectric β and γ phases. However, the most stable phase at ambient temperature and pressure is the nonpolar and paraelectric α phase, which serves as a long-standing issue. Herein, chitosan was introduced into the PVDF matrix to promote the transition from α phase to β phase via the interaction between the –OH and –NH2 groups in chitosan and the H and F atoms in PVDF. As evidenced, the portion of the β phase increased from 47.9 to 63.7%. An electrospinning technique was adopted to prepare PVDF/chitosan composites with a chitosan content ranging from 1 to 4 wt %, and the correlation between structural characteristics and piezoelectric properties is illustrated in detail. Then, a flexible pressure sensor based on PVDF/chitosan composite was prepared, which presents a low detection limit of ∼220 Pa in a wide range of 220 Pa–81 kPa. The pressure sensor presents a good capability for detecting pulse signals and speech recognition accurately. As well demonstrated in this work, the treatment of PVDF with low-cost chitosan may boost its practical application in future flexible electronics.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Shiyu Chen,Xiaoe Chen,Gaofeng Yuan
Biocompatible and degradable hydrogels are extensively utilized for the delivery and controlled release of bioactive agents. Chitosan/squid ring teeth protein (SRT) hydrogels (CH/SRTs) cross-linked by genipin were fabricated, and their gel properties and structural characteristics were analyzed across varying SRT contents. Additionally, the curcumin-release behavior of curcumin-loaded CH/SRTs (Cur-CH/SRTs) was evaluated. Results indicated that increasing SRT content enhanced the elasticity, viscosity, gel strength, hardness, and thermal stability of CH/SRTs. Specifically, the hardness and gel strength of CH/SRT3 (Chitosan: SRT, 1:1) were 207.8 % and 220.9 % higher, respectively, than those of the pure chitosan hydrogel. Higher SRT content significantly increased the curcumin encapsulation efficiency of Cur-CH/SRTs while substantially reducing curcumin release in simulated gastrointestinal fluid. Compared to the curcumin-loaded pure chitosan hydrogel, the curcumin release rate of Cur-CH/SRT3 decreased by 56.12 % after 480 min of simulated gastrointestinal digestion. These findings were attributed to reduced swelling and improved gel strength of Cur-CH/SRTs with SRT addition. Consequently, CH/SRTs demonstrate potential for applications in the controlled release of drugs and bioactive agents.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Mengqiao Wu,Jiawei Lu,Yan Zhang,Zhixin Ling,Ruohui Lu,Jie Zhu,Yongfu Li,Yanjiang Cai,Hai Xiang,Zuyong Zhang,Bing Yu
Slow-release fertilizers show great promise for advancing agricultural sustainability by enhancing nutrient efficiency and mitigating environmental impacts. Herein, we propose an approach that embeds chitosan hydrogel membranes with metal-modified biochars to encapsulate N-P-K compound fertilizers, referred to as CS-MBC-SRFs. Our results demonstrate that CS-MBC-SRFs exhibit superior slow-release performance for N, P, and K compared to others (commercial NPK compound fertilizers, chitosan-coated, and biochar-embedded chitosan-coated fertilizers). Over a 33-day soil column test, CS-MBC-SRFs showed cumulative leaching ratios of <8.93 % for N, 18.4 % for P, and 14.4 % for K. Incorporating metal-modified biochar into the chitosan hydrogel membrane significantly enhances its swelling and mechanical properties while maintaining biodegradability and water-retention capacity. Mechanistic investigations reveal that nutrient release from CS-MBC-SRFs primarily occurs via diffusion through the hydrogel membrane, with the metal-modified biochar surface enhancing nutrient adsorption and delaying release. Additionally, the metal-modified biochars improved swelling and mechanical properties of the chitosan hydrogel membrane, significantly reducing nutrient diffusion. Pot tests demonstrated that CS-MBC-SRFs effectively promoted chili plant growth, ensuring high N-P-K utilization and improving chili fruit nutritional indices. Economic analysis further highlights the promising application prospects of CS-MBC-SRFs.
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FOOD CHEMISTRY
·
2024
·
IF 8.5
Mengyu Liu,Peiying Zhang,Yanwen Wu,Jie Ouyang
To address the challenge of preserving fresh chestnuts, chitosan (CS), hydroxypropyl methylcellulose (HPMC), nisin (N), and sodium alginate (SA) were utilized in the preparation of a bilayer edible film named CS-HPMC-N/SA, which was compared to the monolayer films CS-HPMC and CS-HPMC-N. In comparison to the CS-HPMC film, the CS-HPMC-N and CS-HPMC-N/SA films exhibited increased water vapor permeability (WVP), oxygen permeability, and thickness, while transparency, tensile strength (TS), and elongation at break (EAB) were reduced. The bilayer film CS-HPMC-N/SA showed higher WVP, transparency, thickness, and EAB, but lower TS than the monolayer film CS-HPMC-N. The chestnuts coated with CS-HPMC-N/SA showed lower respiratory intensity and decay rate compared to those coated with CS-HPMC and CS-HPMC-N. These results suggested that the bilayer film CS-HPMC-N/SA, containing nisin, has potential as an edible material for preserving fresh chestnuts.
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Materials Today Communications
·
2024
·
IF 3.7
Kejin Yu,Lina Yang,Siyu Zhang,Hong Song,Shengnan Wang,He Liu
Pb (II) and Cu (II) are the most critical metal ion pollutants commonly found in wastewater, and prolonged exposure to these metal ions can pose serious risks to human health. Therefore, the removal of these pollutants from wastewater is of particular importance. In this study, soy hull nanocellulose/sodium alginate/chitosan (SHNC/SA/CS) hydrogel microspheres were prepared using the ion crosslinking method, and they were used to adsorb Pb (II) and Cu (II) present in wastewater. The SHNC/SA/CS hydrogel microspheres exhibited excellent toughness (18.67 MPa) and hydrophilicity (21.43° ± 0.65°), which improved their reuse rate. Furthermore, hydroxyl, carboxyl and amino groups served as excellent chelating groups and considerably improved the adsorption efficiency of the SHNC/SA/CS hydrogel microspheres. The SHNC/SA/CS hydrogel microspheres exhibited an ultrahigh adsorption rate and an outstanding adsorption capacity for Pb (II) and Cu (II), with an equilibrium adsorption period of 50 min. The equilibrium adsorption capacities for Pb (II) and Cu (II) reached 116.62 and 94.32 mg/g, respectively. Furthermore, the SHNC/SA/CS hydrogel microspheres maintained a removal rate of up to 80 % for Pb (II) and Cu (II) after 10 adsorption–desorption cycles, demonstrating their potential for reuse. The SHNC/SA/CS hydrogel microspheres demonstrated an adsorption performance superior to that reported for CS-based adsorption materials. Moreover, X-ray photoelectron spectroscopy revealed that the adsorption mechanisms of SHNC/SA/CS hydrogel microspheres for Pb (II) and Cu (II) included ion exchange, pore filling, complexation and electrostatic attraction. Moreover, a synergistic coordination effect existed between carboxyl and amino groups.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Xiangru Han,Yingqi Mi,Yuting Ji,Mingzhi Sun,Hongxia Tang,Fang Dong,Zhanyong Guo
To improve the antioxidant activity , sulfhydryl groups (-SH) were introduced into chitosan. Acylated chitosan derivatives, chitosan cationic salt derivatives, hydroxypropyl trimethylammonium chloride chitosan quaternary ammonium salt (HACC) derivatives and N,N,N -trimethyl chitosan iodine (TMC) derivatives were obtained. The chitosan derivatives were characterized by FTIR and 1 H NMR to confirm the successful synthesis. Ellman's reagent was used to determine that the compound contained free sulfhydryl groups. The water solubility and thermal stability of chitosan and derivatives were evaluated. The antioxidant activities of the derivatives were verified, including DPPH radical scavenging activity, superoxide anion radical scavenging activity and reducing power activity. The novel chitosan derivatives showed excellent antioxidant activities. Toxicity assay used L929 cells proved that the derivatives had no significant toxic. The results showed that the chitosan derivatives bearing sulfhydryl groups described in this paper has a certain antioxidant effect, which provides a practical approach for further study of chitosan.
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ACS Applied Nano Materials
·
2024
·
IF 5.3
Lihuan Zhao,Yanyan Li,Yuwen Wang,Changjing Li,Yulong Chen,Mingzhu Yuan
Wearing a compression garment (CG) can effectively prevent and treat hypertrophic scars (HS), but the surface of CG is prone to bacterial growth. Therefore, it is particularly important to carry out antibacterial finishing on compression garment fabric (CGF). In order to achieve the purpose of synergistic antibacterial action, improving bacteriostatic rate, and enhancing biological safety, this study prepared a composite material of MXene (Ti3C2Tx), chitosan, and amino silane coupling agent (3-aminopropyl)triethoxysilane (APTES) and its antibacterial CGF. The binding mechanism between the antibacterial composite material and the CGF was explored, and the bacteriostatic rates, wearing properties, and wash fastness of the antibacterial CGF were studied. Results showed that Ti3C2Tx, chitosan, and APTES were covalently bonded to the CGF, achieving synergistic antibacterial effects. The antibacterial CGF without washing showed a bacteriostatic rate of 99.9% against both Gram-negative bacteria Esherichia coli (E. coli, AATCC 6538) and Gram-positive bacteria Staphylococcus aureus (S. aureus, AATCC 25922), with washing fastness reaching grade AA. Additionally, the comfort of the antibacterial finishing fabric was affected to a certain extent in terms of flexural rigidity and air permeability, but overall, the wearability of the antibacterial CGF also met the daily wearing needs of patients.
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RSC Advances
·
2015
·Vol. 5
·期 110
·90969-90975
·
IF 3.84
Jian Li,Yanqing Xu,Mengqing Hu,Jiangnan Shen,Congjie Gao,Bart van der Bruggen
The application of electrodialysis (ED) for desalination requires the use of natural seawater or river water, in which the presence of multivalent ions is inevitable. This currently limits the process performance. Membranes with selectivity for monovalent ions may overcome this limitation. This study used the method of electro-deposition with chitosan/aniline polymer as a modification material to coat a commercial anion exchange membrane in view of obtaining selectivity for monovalent ions. Chitosan was grafted with polyaniline through copolymerization using ammonium persulfate as an initiator. FTIR spectra of the composites revealed that there was a strong interaction between substituted polyanilines and chitosan. The method was used to prepare a series of membranes by varying the aniline ratio and polymerization time. The chemical composition and surface properties of the membranes were characterized by Fourier transform infrared (FTIR) spectroscopy and scanning electron microscopy (SEM), respectively. Current–voltage curves and resistance were measured to characterize the transport properties of the membranes and the membrane conductivity. The results show that the membrane conductivity increases with the aniline ratio; the selectivity initially increases with the aniline ratio, and then decreases again. The optimum modification condition was an electrodeposition time of 4 h with an aniline ratio of 0.4. Using the modified membrane in concentrated sea water, it was demonstrated that the modified membrane has an excellent selectivity towards monovalent cations.
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Materials Science & Engineering C-Materials for Biological Applications
·
2017
·
IF 4.164
Juan Shen,Bo Jin,Yong-cheng Qi,Qi-ying Jiang,Xue-feng Gao
The implant-associated infection remains a serious problem in clinic. A better compromise between the anti-infection property and biocompatibility of bone filling materials is still required. In this work, carboxylated chitosan/silver-hydroxyapatite (CMCS/Ag-HA) hybrid microspheres were fabricated via a facile gas diffusion method. CMCS and Ag ion were evenly distributed into hybrid microspheres. CMCS regulated the morphological characteristics of the as-synthesized hybrid microspheres. As the content of CMCS increased, the size of the sample increased and dispersion exacerbated. In addition, antimicrobial studies demonstrated that CMCS/Ag-HA hybrid microspheres exhibited an excellent antimicrobial activity against Staphylococcus aureus because of the synergistic effect of Ag + and CMCS. In vitro cell tests indicated that the as-prepared CMCS/Ag-HA hybrid microspheres promoted the proliferation and adhesion of MG63 cells. CMCS/Ag-HA hybrid microspheres showed excellent bactericidal property and biocompatibility; thus, they could be used in biomedical applications, such as infection-resistant bone replacement materials.
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