CHEMICAL ENGINEERING JOURNAL
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2021
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IF 13.273
Jun Cao,Qing Sun,Ai-Guo Shen,Bing Fan,Ji-Ming Hu
Killing harmful bacteria in biofilms is a major challenge for current root canal therapy. Although traditional chemical disinfectants have a good bactericidal effect on plankton, they have little efficiency for the removal and sterilization of bacterial biofilms, and even lead to the emergence of bacterial resistance and high toxic side effects. Herein, we propose for the first time biosafe nanocomposites that integrate photothermal and peroxidase-like catalytic activity for efficient removal and killing of bacterial biofilms in root canals. The integration of gold (core) and copper (Ⅰ, Ⅱ) sulfide (shell) shows excellent catalytic effect, which can catalyze the decomposition of hydrogen peroxide at biosafe concentrations to hydroxyl radicals for efficient removal of biofilms. Moreover, studies on the mechanism of antibiofilm showed that the nanocomposites ( [email protected] 2-x S) have significant degradation effects on proteins and polysaccharides-the main components of biofilm. The in vitro results indicated that the synergism of free radical and heat shows higher sterilization rate against both gram-positive Enterococcus faecalis and gram-negative Fusobacterium nucleus , compared with free radical and heat treatment alone. More importantly, the bactericidal results on isolated dental slices and in root canal models and beagle dog demonstrated the [email protected] 2-x S is highly effective in inactivating the bacteria in biofilms. Hence this safe and synergistic antimicrobial system has great potential in antibiofilm-oriented root canal therapy.
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LUMINESCENCE
·
2021
·Vol. 36
·期 6
·1513-1524
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IF 2.464
Huan Zhang,Zhenzhen Li,Huaying Huang,Si Ouyang,Yiqing Deng,Qiang Zhao
Near-infrared (NIR) core–shell CdSeTe/CdS quantum dots (QDs) modified with l -cysteine were synthesized in aqueous solution. The QDs had a special NIR-emitting spectrum, high fluorescence stability and low cytotoxicity. In addition, they exhibited an obvious fluorescence quenching when Cu 2+ was present. An NIR nanosensor was prepared for rapidly, sensitively, and selectively determining Cu 2+ in solution quantitatively and monitoring the changes in Cu 2+ in cells with fluorescence imaging in a semiquantitative way. The linear relationship between the relative fluorescence intensity (F 0 /F) and the concentration of Cu 2+ from 5.12 × 10 −8 M to 2.56 × 10 −5 M in solution was observed using an NIR fluorescence spectrophotometer with R 2 equal to 0.9958. Moreover, in the experiment with the fluorescence microscope, F 0 /F versus the concentration of Cu 2+ from 5.00 × 10 −8 M to 7.68 × 10 −6 M also showed a good linear relationship with R 2 equal to 0.9817. Practical water sample ion detecting experiments had good accuracy and recovery rates. Cell experiments showed that the NIR imaging intensity of cells was inversely proportional to the concentration of copper ions, therefore NIR QDs have great potential for detection of metal ions in solution and in cells.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2021
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IF 3.764
Qiang Wang,Wenchang Wang,Qiuying Li,Chifei Wu
A metal–ligand complex is a useful noncovalent bond to build up a cross-link network. Unfortunately, it is a challenge to construct the coordination cross-link networks in commercial elastomers without ligand groups on their polymer chains. In this study, first, a tetrazine click reaction using 3,6-di(2-pyridyl)-1,2,4,5-tetrazine (DPT) successfully introduced nitrogen-containing groups into styrene–butadiene rubber (SBR) polymer chains with a facile process in the solid status. Then, the introduced groups on SBR could further coordinate with Cu2+ after mixing with CuSO4 and heating under pressure in bulk. Differential scanning calorimetry, Fourier-transform infrared spectroscopy, 1H NMR, X-ray photoelectron spectroscopy, and thermogravimetric analysis proved the modification of SBR by DPT, as well as the coordination between ligand groups on SBR and CuSO4. Elastic torque curves effectively monitored the formation of coordination cross-link networks. Finally, due to the reversible breaking and re-forming nature of metal–ligand bonds, the coordination cross-linked SBR exhibited high strength and toughness. Tensile strength up to 10.52 MPa at a fracture elongation of 695% was obtained when the designed DPT click reaction degree is 2% and the content of CuSO4 is 10 phr. The corresponding composite exhibited some recycling value, and the related fracture energy could sustain 58.9 and 30.7% compared to the virgin sample after being reprocessed once and three times, respectively. Thus, in this work, a simple approach was developed to convert widely used SBR into mechanically robust materials via metal–ligand bonds with some reprocessing and recycling ability without using any conventional vulcanizing agent and accelerator.
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JOURNAL OF HAZARDOUS MATERIALS
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2020
·
IF 9.038
Yiying Yue,Jiamin Gu,Jingquan Han,Qinglin Wu,Jianchun Jiang
Novel portable, high-precision, and reusable fluorescent polyvinyl alcohol (PVA)-borax hydrogel sensors were prepared to detect Cu 2+ in aqueous environment. A TEMPO-oxidized cellulose nanofibers/salicylaldehyde thiosemicarbazone (TOCN/ST) complex was further incorporated into the PVA-borax matrix. The in situ polymerization of TOCN/ST complex enhanced the mechanical properties of the hydrogels and improved the accuracy of detection. The resultant hydrogels were thermo reversible, and it converted to the liquid state during heating, which could greatly reduce the deviations caused in the detection of solid sensors. After cooling, the hydrogel could transform into the solid condition, which was easily portable. The sensor induced a significant luminescence quenching to the Cu 2+ at 485 nm, with a detection limit of 0.086 μM. In the presence of ethylenediaminetetraacetic acid disodium, Cu 2+ were tightly seized, causing the liberation of TOCN/ST complex and thus, a reversible “ON-OFF-ON” fluorescence behavior was displayed. The fluorescence intensity was maintained at 82 % after 10 uses, and the mechanical strength was maintained at 85 % after 3 uses. The anti-bacterial activity test also confirmed the TOCN/ST complex was extremely potent in suppressing the growth and reproduction of Escherichia coli . The proposed hydrogel provides a new insight into the detection of Cu 2+ in aqueous environments.
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高影响因子
CURRENT APPLIED PHYSICS
·
2020
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IF 2.281
Bo Gao,Da Chen,Bingli Gu,Ting Wang,Zihao Wang,Feng xie,Yongsheng Yang,Qinglei Guo,Gang Wang
Nitrogen-doped graphene quantum dots (N-GQDs) with high blue fluorescence efficiency were synthesized by the hydrothermal method from p-Phenylenediamine and p-Coumaric acid. The N-GQDs possess several superiorities, most significantly in excellent solubility and superior photostability. Besides, the as-prepared N-GQDs exhibit a uniform size distribution with a diameter of about 3.8 ± 0.5 nm. After dispersing the N-GQDs in water, the formed aqueous solution still presents a stable and homogeneous phase even after 2 months at room temperature. The N-GQD dispersion was further utilized as sensing probes for the selective detection of copper ions (Cu 2+ ), which is realized by the photoluminescence (PL) quenching of N-GQDs after adding Cu 2+ . The detection limit for Cu 2+ was found to be 57 nM L −1 , with superior selectivity in the presence of other commonly interfering metal ions . The presented results in this study provide a facile and high-efficiency method for synthesizing N-GQDs, with ultra-high detectivity and selectivity for Cu 2+ detection, offering numerous opportunities for the development of biosensing, bioimaging, environment monitoring, and others.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2020
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IF 3.232
Wenjun Zhou,Qiang Gao,Darui Liu,Chen Li,Shu Liu,Kaisheng Xia,Bo Han,Chenggang Zhou
A novel salicylaldehyde bis-Schiff-base probe decorated with imidazolium ionic liquid moieties at both ends (SAS-IMIs) was designed and facilely synthesized as a colorimetric/ratiometric sensor to visually detect Cu 2+ and Pd 2+ in pure aqueous media. Due to the positively charged characters of its head and tail, the SAS-IMIs exhibited high water solubility with a potential advantage in minimizing the self-aggregation. More importantly, simply by varying the solution pH, colorimetric/ratiometric sensing detection of individual metal ion (Cu 2+ or Pd 2+ ) was realized without any mutual interference. Subsequently, sensitive, selective, and differential detections for Cu 2+ (LOD: 0.080 μM) and Pd 2+ (LOD: 0.076 μM) in 100% aqueous solutions were achieved, which proved to be applicable for real water samples. Results from density functional theory (DFT) calculations unveiled the Cu 2+ /Pd 2+ -binding properties of SAS-IMIs, which were in accordance with the experimental observations. Furthermore, a SAS-IMIs-based solid phase sensor was fabricated, which manifested satisfactory detection abilities for Cu 2+ and Pd 2+ .
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高影响因子
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
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2020
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IF 3.306
Xiaoning Qin,Qiao Tong,Mingyue Chang,Shucai Liang
A hydrophilic polymer-based nanoparticles named PEIN was developed as a new bifunctional nanosensor for sequential fluorescence sensing of Cu 2+ and biothiols. PEIN could be easily prepared via a one-pot grafting reaction between commercially accessible polyethyleneimine and ninhydrin in water solution at room temperature for 1 h. In phosphate buffered aqueous media (pH5.0), the strong fluorescence of PEIN at 444 nm (excited at 360 nm) was rapidly and effectively quenched by Cu 2+ over the other common metal ions. The quenching mechanism has been proved to be a static process owing to the binding of PEIN with Cu 2+ . In addition, the reduced fluorescence of PEIN could return immediately upon the addition of biothiol (Cys or GSH) in PEIN-Cu 2+ system, but not recover with the attendances of other non-thiol amino acids. Therefore, PEIN was able to be used for the selective detection of Cu 2+ by fluorescence “turn off” mode, and the in site formed PEIN-Cu 2+ ensemble could be applied for determining biothiols by fluorescence “turn on” mode. Furthermore, in view of the fluorescence “on-off-on” switches of PEIN caused by Cu 2+ and Cys (or EDTA), a two-input molecular logic gate performing IMPLICATION operation was successfully constructed by employing PEIN as the communication material.
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JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS
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2020
·Vol. 109
·期 1
·50-59
·
IF 2.831
Yansong Wang,Xin Chu,Yu Sun,Peng Teng,Tianzhi Xia,Yisheng Chen
Rapid and convenient wound healing is crucial for reducing potential post-traumatic wound complications. In this study, a temperature-sensitive polymer of poly-(HEMA-co-NIPAM) (PHN) was synthesized by free-radical polymerization, in which the solution quickly underwent a sol–gel transition above 29°C, thus responding to a typical body temperature and facilitating wound sealing. PHN solution incorporated with copper ions (PHN-Cu) not only exhibited excellent antibacterial properties, but also expedited wound closure and facilitated tissue angiogenesis. The in vivo and in vitro experiments showed that the PHN-Cu had a higher wound closure rate and demonstrated an ability to promote skin tissue angiogenesis. Such a versatile, convenient aqueous solution could enable nonprofessionals to promptly treat wounds in a short time after injury, thus providing suitable conditions for later treatment, and can be used as a convenient method to clean wounds.
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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2019
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IF 3.571
Yong Han,Weixia Yang,Xueli Luo,Xie He,Ying Yu,Chunhua Li,Wenzhi Tang,Tianli Yue,Zhonghong Li
Copper ion (Cu2+)-triggered carbon dots (CDs/Cu) with dual emissions were utilized to develop a ratiometric fluorescence sensor for ultrasensitive detection of inert thiophanate-methyl (TM). TM could be recognized by CDs/Cu through π–π stacking and could chelate Cu2+ of CDs/Cu through metal ion coordination, inducing synchronous fluoresent quenching of the dual emission of CDs/Cu based on the excited state intramolecular proton transfer and the ligand-to-metal charge transfer. The fluorescence ratio of CDs/Cu (F416/F481) linearly responded in a TM concentration of 0.10–20.00 μmol/L with an ultralow limit of detection of 2.90 × 10–6 μmol/L. A synchronous response of the ratiometric sensor enhanced the specificity toward TM and presented remarkable capability of anti-interference in complex matrices. The sensor exhibited satifactory accuracy and precision for practical applications with recoveries of 88.33–101.09% and relative standard deviations of 1.61–5.06%, demonstrating an ultrasensitive ratiometric fluorescent nanosensor for detecting pesticides residues in complex matrices.
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JOURNAL OF MOLECULAR LIQUIDS
·
2019
·
IF 4.561
Yang Wang,Si Sun,Lin Shi,Pengcheng Gao,Yingying Wei,Chuan Zhang,Yong Jiang
A facile and energy-efficient synthesis of Fe 3 O 4 @SiO 2 -PHEMA complex and its application as adsorbent for removal of Cu 2+ from aqueous solution were investigated. Fe 3 O 4 @SiO 2 -PHEMA was synthesized by mixing Fe 3 O 4 @SiO 2 and HEMA monomer and then initiating the polymerization of HEMA monomer by H 2 O 2 under Fe 2+ catalyzing at room temperature . As adsorbent, the maximum sorption capacity of Fe 3 O 4 @SiO 2 -PHEMA for Cu 2+ was calculated to be 20.7 mg/g at pH 6.0. And the efficient enrichment of Cu 2+ on Fe 3 O 4 @SiO 2 -PHEMA depended on its multiple carbonyl groups and the electrostatic interaction between carboxyl groups and Cu 2+ . The carboxyl groups were from slow hydrolysis of partial ester bonds of PHEMA under acidic conditions. The possible hydrolysis process of ester bonds was facilitated to avoid sorption capacity of Cu 2+ decreasing caused by other ions sorption (like Fe 2+ ) during the synthesis of the adsorbent. The adsorption of Cu 2+ on Fe 3 O 4 @SiO 2 -PHEMA coincided with Langmuir model. The Fe 3 O 4 @SiO 2 -PHEMA had good dispersity in water and it could be easily collected from wastewaters by a magnet. The results showed that Fe 3 O 4 @SiO 2 -PHEMA was a promising adsorbent in wastewater treatment.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2023
·
IF 4.4
Huan Wang,Wencheng Mu,Siying Wang,Lin Shi,Tianfeng Ma,Yongchang Lu
In this paper, a novel nitrogen and sulfur co-doped carbon quantum dots (NS-CQDs) were successfully prepared by a dehydration exothermic carbonization method. The NS-CQDs exhibited uniform size distribution, splendid photostability, and bright fluorescence emission with a fluorescence quantum yield of 24.1 %. It was found that Cu 2+ could quench the fluorescence at 467 nm based on the static quenching effect when Cu 2+ was added to the NS-CQDs. At this time, the fluorescence sensor changed from the “ON” state to the “OFF” state. When glutathione (GSH) was further introduced into the NS-CQDs/Cu 2+ system, the fluorescence intensity of NS-CQDs was amazingly restored through the coordination reaction between GSH and Cu 2+ . The fluorescence sensor changed from the “OFF” state to the “ON” state. Therefore, NS-CQDs as an “ON-OFF-ON” fluorescence sensor was designed for sequential detection of Cu 2+ and GSH. Furthermore, this study successfully demonstrated the sensor’s ability to selectively detect Cu 2+ and GSH within a wide concentration range. Specifically, the detection range for Cu 2+ was 0.1 μM−200.0 μM with a detection limit of 0.07 μM, while the range for GSH was 0.6 μM−180.0 μM with a detection limit of 0.1 μM. Most importantly, the NS-CQDs nanosensor could reliably monitor Cu 2+ and GSH levels in human serum samples, with significant potential for practical applications.
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高影响因子
Crystals
·
2023
·Vol. 13
·期 5
·812
·
IF 2.7
Yuanyuan Xiong,Mengxiao Chen,Zhen Mao,Yiqing Deng,Jing He,Huaixuan Mu,Peini Li,Wangcai Zou,Qiang Zhao
Carbon dots have drawn extensive attention in the detection of metal ions with good stability, excellent biocompatibility and low toxicity. Meanwhile, the quantum yield, response rate and the detection mechanism for Cu2+ions are vital to their development and application. To obtain more selective and sensitive materials to detect Cu2+ions, N-doped carbon dots (DN-CDs) were synthesized by a one-step hydrothermal method using citric acid as the carbon source and diethylenetriamine (DETA) as the nitrogen source. The obtained DN-CDs exhibited stable and intense blue light emission and special near-infrared up-conversion fluorescence at 820 nm, attributed to the effect of introducing N atoms into the structure of carbon dots. Due to the dynamic quenching of the DN-CDs by Cu2+ions, the fluorescence intensity (λex = 820 nm) of DN-CDs was quantitatively decreased in the presence of Cu2+ions. The DN-CDs had a rapid response within 3 min. The DN-CD system exhibited a linear relationship with a concentration range from 2.5 to 50 µM and low detection limit (LOD) of 42 nM. After careful investigation, an interesting conclusion was proposed: N-doped CDs with N/O = 1:1 or higher with relatively abundant N atoms prefer to detect Cu2+ions while those with N/O = 1:2 or lower prefer to detect Fe3+ions.Keywords:carbon dots;up-conversion fluorescence;Cu2+ions detection
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