ARABIAN JOURNAL FOR SCIENCE AND ENGINEERING
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2026
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IF 3.1
Ho Thanh Gia-Thien,Nguyen Phung Anh,Tran-Pham Phuong Khanh,Phan Hong Phuong,Pham-Nguyen Ai Vi,Nguyen Thi Thu Thuy,Do Ba Long,Nguyen Duc Quy,Le Thanh Quang,Pham Thi Thuy Phuong,Van Nguyen Thi Thuy,Nguyen Tri
Developing fully sustainable and recyclable catalysts from agricultural waste remains a major challenge for advanced wastewater treatment. Herein, we report an integrated, zero-waste strategy to fabricate a hierarchically structured Ag/ceria-cellulose porous catalyst derived exclusively from purple Passiflora edulis peel waste. Phytochemical-rich peel extracts were employed as green reducing and stabilizing agents for the in situ synthesis of Ag nanoparticles, while the residual cellulose-rich biomass was converted into a three-dimensional porous aerogel via microwave-assisted extraction and freeze-drying. Incorporation of ceria nanorods endowed the aerogel with abundant oxygen vacancies and strong metal–support interactions, effectively suppressing Ag nanoparticle agglomeration and promoting interfacial electron transfer. The optimized Ag/ceria-cellulose aerogel exhibited uniformly dispersed Ag nanoparticles with an average size of 7.84 nm. Under mild conditions (0.5 wt% Ag loading, catalyst dosage of 0.5 g L −1 , and MO/NaBH 4 molar ratio of 1/200), over 95% of methyl orange was reduced within 30 min, following pseudo-first-order kinetics with an apparent rate constant of 0.14 min −1 . Owing to its monolithic and mechanically robust architecture, the aerogel catalyst could be readily recovered by simple filtration and retained more than 75% of its initial activity after five consecutive cycles. The superior catalytic performance and durability originate from the synergistic interplay between Ag nanoparticles, oxygen vacancy-rich ceria nanorods, and the interconnected cellulose aerogel matrix, which collectively enhance active-site accessibility, charge transfer efficiency, and structural stability. This work demonstrates a scalable and circular pathway for transforming passion fruit peel waste into high-value, reusable catalysts for wastewater remediation.
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高影响因子
NEUROCHEMICAL RESEARCH
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2026
·Vol. 51
·期 5
·257
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IF 4.5
Cao Zhi,Yin Linting,Zhang Xinyong,Hong Enhui,Du Jiansheng,Liang Rui,Tang Youjia,Zhang Guofeng
Spontaneous cerebral hemorrhage (sICH) is one of the cerebrovascular diseases with the highest mortality rate. MicroRNAs (miRNAs) are implicated in the regulation of various pathological processes, however, the specific function of miR-642b-3p in sICH remains unclear. Serum miR-642b-3p levels of sICH patients was determined. A thrombin-induced human brain microvascular endothelial cell (hBMECs) injury model was established. Cell viability, apoptosis, inflammatory factors, and related protein expression were assessed using CCK-8 assay, flow cytometry, ELISA, and Western blot. The targeting relationship between miR-642b-3p and CCNA2 was validated via a dual-luciferase reporter assay. MiR-642b-3p in the serum of ICH patients was significantly increased. Following thrombin induction, miR-642b-3p was upregulated in hBMECs, accompanied by decreased cell viability, increased apoptosis, elevated production of inflammatory factors, upregulated expression of pro-apoptotic proteins (Bax and cleaved caspase-3), and downregulated expression of anti-apoptotic protein (Bcl-2). Additionally, the protein levels of tight junction markers ZO-1 and occludin were markedly decreased. Notably, inhibition of miR-642b-3p significantly reversed these thrombin-induced changes and alleviated cell damage. Mechanistically, CCNA2was confirmed as a direct downstream target gene of miR-642b-3p. MiR-642b-3p is upregulated in sICH and mediates thrombin-induced endothelial cell injury, at least in part, by targeting CCNA2. These findings suggest that the miR-642b-3p/CCNA2 axis may represent a potential mechanistic pathway involved in ICH-induced blood-brain barrier disruption.
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JOM
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2026
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IF 2.3
Xiang Zhe,Xu Chengjin,Yu Haiyin,Wang Zhimei,Sun Guoxin,Cui Yu,Peng Xiujing
Titanium white waste acid contains economically recoverable concentrations of scandium (25 mg/L); however, the high acid content and presence of multiple impurity ions present significant challenges for scandium separation. In this study, a novel monoalkyl phosphate extractant, PC68, consisting of 1-hexadecyl phosphate and 1-octadecyl phosphate, was synthesized. The effects of extraction time, sulfuric acid concentration, and temperature on scandium extraction were systematically investigated using a simulated titanium white waste acid solution. The results demonstrated that equilibrium was reached within 50 min at 298 K, and that the extraction efficiency of scandium with 0.1 mol/L PC68 was 99%. Analytical techniques, including the Equimolar Series Method, FT-IR, and XPS, confirmed that PC68 extracts scandium through coordination with P-O − and P=O groups. The separation performance of scandium from titanium white waste acid was evaluated, yielding high separation factors of 1093 for Sc/Fe and 733 for Sc/Mn, which demonstrates excellent separation efficiency. The addition of 1% H 2 O 2 followed by three-stage countercurrent extraction enabled effective separation of scandium and titanium. These results provide new insights and practical approaches for scandium separation from titanium white waste acid.
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CELL BIOLOGY AND TOXICOLOGY
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2026
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IF 5.7
Zhao Bingbing,Zhang Zhengwei,Li Xiaoxue,Dong Shiyun,Zhong Xin,Li Zhitao,Jin Ye,Bai Yun,Wei Can
Liver fibrosis represents a major unmet clinical challenge, and induction of hepatic stellate cell (HSCs) senescence has emerged as a promising therapeutic strategy to halt or reverse fibrotic progression. PPARγ is a key regulator of HSCs quiescence; however, the downstream molecular mechanisms mediating its pro-senescence effects remain poorly defined. Here, we demonstrate that PPARγ expression is markedly reduced in a CCl₄-induced mouse liver fibrosis model and that its restoration drives HSC inactivation and senescence. Through integrated bioinformatics analysis and functional validation in PPARγ-overexpressing HSC-T6 cells, we identified leukemia inhibitory factor receptor (LIFR) as a direct transcriptional target of PPARγ. Mechanistically, PPARγ upregulates LIFR to suppress STAT3 phosphorylation, thereby downregulating fibrosis markers CO Ⅰ and α-SMA, elevating P21 and γ-H2A.X, and reducing CCND1. Crucially, LIFR knockdown abolished all PPARγ-mediated effects, confirming its indispensable role in this axis. Furthermore, combined treatment with the STAT3 inhibitor WP1066 synergistically enhanced PPARγ-driven HSC senescence in a LIFR-dependent manner. These findings establish a PPARγ-LIFR-STAT3 signaling cascade as a critical regulator of HSCs fate, and suggest that pharmacological activation of this axis represents a tractable approach for fibrosis resolution.
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JOURNAL OF NANOBIOTECHNOLOGY
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2026
·Vol. 24
·期 1
·184
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IF 15
Li Qingchen,Chen Lixue,Sun Yi,Wang Changyuan,Sun Yilun,Lu Kangjun,Li Lei,Sun Huijun,Liu Mozhen
PANoptosis, a distinct type of inflammation-associated programmed cell death that integrates features of apoptosis, necroptosis and pyroptosis, is closely related to the pathogenesis and progression of articular cartilage degeneration in osteoarthritis (OA). Meanwhile, excessive reactive oxygen species (ROS), pro-inflammatory pathways, and inflammatory cytokines in the OA microenvironment mutually reinforce one another, exacerbating synovial inflammation. To simultaneously target these interconnected pathological drivers, we developed an injectable nanocomposite thermosensitive hydrogel (DHA-PRO@NMs@TSH). This hierarchical system was constructed by integrating a ROS-responsive dihydroartemisinin prodrug (DHA-PRO) into Soluplus/TPGS-based nanomicelles (NMs), which were subsequently embedded within a Poloxamer-based thermosensitive hydrogel (TSH). This hierarchical and smart drug delivery system enables stable dihydroartemisinin (DHA) delivery and demonstrates a graded, ROS-triggered release profile, achieving sustained DHA retention in OA joints. The formulated system demonstrated excellent injectability, thermosensitivity, and physicomechanical stability, achieving sustained drug retention in rat joints for over 7 days, as confirmed by in vivo imaging. In vitro studies demonstrated that DHA-PRO@NMs significantly suppressed PANoptosis in chondrocytes by downregulating key markers (e.g., Bax/Bcl-2, RIPK3/p-RIPK3, NLRP3/Caspase-1/GSDMD) and inhibited inflammation by blocking the NF-κB pathway and subsequent cytokine production (e.g., TNF-α, IL-1β). In a rat OA model, treatment with DHA-PRO@NMs@TSH robustly attenuated disease progression, as evidenced by near-complete restoration of gait function, marked inhibition of cartilage degradation, a remarkable nearly 90% reduction in the Mankin score, and a comprehensive suppression of PANoptosis and inflammation pathological markers. This work not only presents a promising translational strategy for OA but also pioneers a therapeutic paradigm of leveraging advanced drug delivery system to dual-targeting PANoptosis and inflammation. Graphical abstract
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Science China-Chemistry
·
2026
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IF 9.8
Fang Pengda,Yuan Han,Zhou Tao,Yuan Yongjiang,Zhang Jiale,Zhang Qiuhuan,Zhang Hao,Yu Qikun,Sun Zhe,Yan Feng
Anion exchange membrane fuel cells (AEMFCs), recognized as a cost-effective solution for hydrogen energy utilization, have been extensively investigated in thousands of research articles. However, the performance of the anion exchange membranes (AEMs) under operating conditions still falls short of practical requirements. The challenge resides in the current emphasis on analyzing the intrinsic properties of AEMs without explicitly linking these properties to the performance of terminal devices. We developed a comprehensive machine learning model for predicting and optimizing AEMFC power density, encompassing AEM properties, catalyst layer composition, and operating conditions. Having learned from extensive experimental data, the model demonstrates generalization capability, accurately predicting performance for unseen data with an overall error rate below 10%. By implementing the data-driven optimization strategy recommended by the model, the power density of AEMFCs improved by up to 20%. This approach effectively links material-level characteristics to system-level performance, offering a novel perspective on precision-oriented and systematic energy materials innovation.
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POLYMER BULLETIN
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2026
·Vol. 83
·期 7
·401
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IF 4.2
Liu Deyu,Ba Xuan,Wu Shaoyuan,Hu Jinghan,Duan Jihong,Guan Xingyu,Zhou Guoyong,Wang Kui,Huang Weijiang,Yan Wei
Waterborne polyurethane (WPU) has the advantage of good flexibility in the coating film, high and low-temperature resistance, and the advantages of environmental protection. Currently, there is a high demand for flame-retardant WPU. Herein, a flame-retardantcomposites (WPU/BN@APP/DIDOPO) is successfully developed by incorporating ammonium polyphosphate (APP) modified boron nitride (BN@APP) and DOPO derivatives into WPU via simple casting technology.The results indicate that BN@APP formed the intended composite structure and was well dispersed in the WPU matrix. This system significantly enhanced the char residue at 700 ℃ from 0.23% to 5.22% and reducing the peak heat release rate (pHRR) and total heat release (THR) by 58.9% and 36.9%, respectively, compared to pure WPU. Performance analysis shows that during combustion, a dense and stable expanded carbon layer forms, effectively delaying heat and mass transfer. The mechanical properties of the WPU/0.5BN@APP/5DIDOPO composite material are optimal and its breaking strength and elongation at break are superior to those of components. This work demonstrates the potential of the BN@APP/DIDOPO composite system for enhancing flame retardancy in polymeric materials, providing valuable insights for designing advanced flame-retardant systems.
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MICROCHIMICA ACTA
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2026
·Vol. 193
·期 9
·605
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IF 5.4
Yi Gui,Wang Wenyan,Xia Qi,Xiao Liqiong,Wang Dekai,Xie Lianwu,Qin Haijiao,Guo Yaping
Early detection of aflatoxins is crucial to safeguard food safety. In this study, a new azobenzene monomer was synthesized and its photo-isomerization behavior in methanol and dimethyl sulfoxide was studied. A photo-switchable molecularly imprinted polymer (PMIP) designed for selectively recognizing aflatoxin B1 (AFB1) was fabricated via a surface imprinting technique. A dummy template, 5,7-dimethoxycoumarin was incorporated during the polymerization process. The photo-responsive behaviors of candidate monomers were systematically evaluated in methanol and dimethyl sulfoxide. The resulting PMIP was used as an extraction adsorbent for pretreatment prior to high-performance liquid chromatography-mass spectrometry analysis with its adsorption capacity could be controlled by light irradiation (365 nm and 440 nm). The method demonstrated a linear calibration interval from 50 to 1000 ng·mL⁻¹ with detection limit of 5.1 ng·mL⁻¹, and exhibited favorable binding capacity values between 90.8% and 95.4% when used for the determination of AFB1 in corn, reflecting the strong recognition affinity of PMIP toward AFB1. Graphical
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JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE
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2026
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IF 2.6
Li Shanjian,Ren Jie
Polydopamine (PDA) coatings have great potential for corrosion protection in harsh acidic industrial environments. However, their performance and failure mechanisms in strongly acidic media at identical H⁺ concentrations but with different anions remain unclear. This work systematically compares the corrosion inhibition behavior of PDA coatings on N80 steel in hydrochloric acid and sulfuric acid media using static weight-loss measurements, potentiodynamic polarization, electrochemical impedance spectroscopy (EIS), UV-Vis spectrophotometry, and surface characterization. The results demonstrate significant anion-dependent behavior. At 25 °C, the corrosion inhibition efficiency reached 96.55% in 0.05 mol L −1 H 2 SO 4 with a coating peeling rate of only 1.22%. In contrast, the efficiency was only 59.72% in 0.10 mol L⁻ 1 HCl with a peeling rate of 3.38%. The charge-transfer resistance was higher and the coating structure was more stable in H 2 SO 4 . Increasing the acid concentration or temperature reduced the protective performance of the coating, with faster degradation observed in HCl. The Mechanistic analysis indicates that small, highly mobile Cl⁻ ions penetrate the coating and disrupt intermolecular interactions, whereas SO 4 2 ⁻ interacts weakly with protonated PDA, thereby preserving coating integrity. These results provide a theoretical basis for designing PDA-based anticorrosion coatings for high-chloride acidic industrial environments.
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高影响因子
Scientific Reports
·
2026
·
IF 4.9
Sikandar Anila,Zhao Jing,Ahmad Shakeel,Chu Gang,Pan Bo,Chang Zhaofeng,Liu Yang,Wu Danping,Rashid Audil
Biochar (BC) has been widely used for the lead (Pb(II)) immobilization in soil remediation. However, the mechanisms of dissolution-driven removal of Pb(II) by BC are still poorly understood. Herein, Pb(II) removal was investigated by differentiating BC- and dissolved organic carbon (DOC)-systems. As per the kinetics and isotherms, Pb(II) removal ranged from 31.11% to 80.92% in BC-system. This removal process was significantly influenced by dissolution-driven precipitation which contributed from 23.42% to 84.03% in DOC-system. During Pb(II) removal, an obvious reduction was observed in the released inorganic anions including carbonate (CO 3 2− ), sulfate (SO 4 2− ), and phosphate (PO 4 3− ). The CO 3 2− was a predominant contributor to facilitate Pb(II) precipitation. X-ray diffraction further confirmed the formation of cerussite (PbCO 3 ) and anglesite (PbSO 4 ) on BC surface after Pb(II) removal. Moreover, the decreased fluorescence responses of humic-like and fulvic-like substances were detected in DOC-system with the addition of Pb(II). At the same anion concentration, the enhanced Pb(II) amount was removed with increasing DOC concentration from 1 mg·L − 1 to 5 mg·L − 1 . These results indicated that released DOC exerted a significant contribution on Pb(II) precipitation due to its coagulation effect. This research provides mechanistic insights into the contributions of adsorption and dissolution-driven precipitation in overall Pb(II) removal through BC application.
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IONICS
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2026
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IF 3.4
Huang Dandan,Ouyang Quan,Guo Pingchun,Jiang Hedong
Zn-ion batteries (ZIBs) have attracted considerable attention as promising energy storage systems owing to their natural abundance, low standard electrode potential (-0.76 V), and high theoretical capacity (820 mAh g − 1 ). Nevertheless, their practical application is severely hindered by Zn dendrite growth, hydrogen evolution, and electrode passivation. To address these challenges, we constructed a Zn-based vermiculite coating on Zn anodes (Ver@Zn), which reduces the direct exposure of Zn to the electrolyte and suppresses side reactions and passivation layer formation. Owing to its unique Zn 2+ interlayer channels and electronic insulating properties, the vermiculite coating facilitates uniform Zn 2+ migration and nucleation, thereby enabling homogeneous Zn deposition. As a result, the modified Zn anode exhibited enhanced corrosion resistance and higher Coulombic efficiency (CE). The vermiculite particle with optimized size (45–61 μm) yielded the best cycling stability, with a symmetric cell lifetime of up to 1700 h, far exceeding that of bare Zn. Furthermore, the Ver@Zn anode delivered superior performance in Zn/I 2 full cells, maintaining high specific capacity, rate capability, and long-term cycling stability (98% capacity retention after 3000 cycles) with CE of 99.8%. This work demonstrates an effective surface engineering strategy for advancing high-performance aqueous Zn iodine battery.
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JOURNAL OF NANOBIOTECHNOLOGY
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2026
·Vol. 24
·期 1
·578
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IF 15
Zhao Zinan,Mutailipu Muladili,Mei Tianxiao,Cui Ran,Wang Yongkun,Liu Fuguo,Dong Chunxiu,Jia Wenwen,Liu Zhongmin,Chen Bo,Le Wenjun,Hu Yihui
Severe acute pancreatitis (SAP) is a life-threatening inflammatory disorder with an approximate mortality rate of 40%. Current therapeutic approaches fail to address its complex pathological microenvironment, necessitating novel synergistic strategies. Although mesenchymal stem cells (MSCs) exhibit therapeutic potential, their efficacy is significantly compromised by SAP-associated oxidative stress, hyperinflammation, and gut dysbiosis. Herein, we engineered MSCs with antioxidant nanozyme PDA@MnO x , named PDA@MnO x -MSCs ( Abbr. E-MSCs), to establish a regulatory network for SAP therapy. The PDA@MnO x nanozymes not only scavenge reactive oxygen species (ROS) to protect MSCs from oxidative damage but also enable in vivo T 1 -weighted MRI tracking. E-MSCs demonstrated enhanced anti-inflammatory effects, evidenced by reduced levels of TNF-ɑ and IL-6, and restored gut microbiota homeostasis, characterized by increased Bacteroidetes abundance. This further alleviated pancreatic necrosis and systemic inflammation. Notably, the synergistic interaction among PDA@MnO x nanozymes, MSCs, and the pathological microenvironment restored ROS-inflammation-microbiota homeostasis, significantly improving SAP outcomes. This study provides a multifunctional strategy integrating therapeutic efficacy, in vivo tracking, and gut microbiota modulation for SAP treatment. Graphical
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