Advanced Healthcare Materials
·
2023
·Vol. 12
·期 18
·2203344
·
IF 10
Qinyi Zhao,Ming Zhu,Gongwei Tian,Cuiyuan Liang,Zhiyuan Liu,Jianping Huang,Qianheng Yuan Yu,Shuanglong Tang,Jianhui Chen,Xizheng Zhao,Qi Zeng,Chongshen Guo,Dianpeng Qi
Flexible electrode array, a new-generation neural microelectrode, is a crucial tool for information exchange between living tissues and external electronics. Till date, advances in flexible neural microelectrodes are limited because of their high impedance and poor mechanical consistency at tissue interfaces. Herein, a highly sensitive and omnidirectionally stretchable polymeric electrode array (PEA) is introduced. Micropyramid–nanowire composite structures are constructed to increase the effective surface area of PEA, achieving an exponential reduction in impedance compared with gold (Au) and flat polypyrrole electrodes. Moreover, for the first time, a suspended umbrella structure to enable PEA with omnidirectional stretchability of up to ≈20% is designed. The PEA can withstand 1000 cycles of mechanical loads without decrease in performance. As a proof of concept, PEA is conformally attached to a rat heart and tibialis anterior muscle, and electrophysiological signals (electrocardiogram and electromyogram) of the rat are successfully recorded. This strategy provides a new perspective toward highly sensitive and omnidirectionally stretchable PEA that can facilitate the practical application of neural electrodes.
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Molecular Catalysis
·
2023
·
IF 4.6
Tingting Ma,Chao Xu,Fengyang Liu,Yirong Feng,Wenyan Zhang,Weiwei Tang,Haoyu Zhang,Xiaowei Li,Yingying Nie,Shuangfei Zhao,Yuguang Li,Dong Ji,Zheng Fang,Wei He,Kai Guo
Selective epoxidation and allylic oxidation of cyclohexene were realized in the presence of BEA-Ti and (metallo)porphyrin catalysts. The integration of BEA-Ti and porphyrin H 2 MTPP afforded cyclohexene oxide with excellent selectivity (cyclohexene oxide/ 2-cyclohexen-1-one=85:15). BEA-Ti and metalloporphyrin MnMTPP yielded 2-cyclohexen-1-one with high selectivity (cyclohexene oxide/ 2-cyclohexen-1-one=12:88). Resulting active species involving of (metallo)porphyrin, Ti IV sites and tert-butyl hydroperoxide (TBHP) promoted the oxidation process of cyclohexene. A possible mechanism resulting in the formation cyclohexene oxide and 2-cyclohexen-1-one was proposed. The outer-sphere effect constructed by (metallo)porphyrin, Ti IV sites and TBHP on the surface of BEA-Ti framework improved the epoxidation and allylic oxidation both in the conversion and selectivity.
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MICROCHIMICA ACTA
·
2023
·Vol. 190
·期 3
·1-12
·
IF 5.7
Chu Zhe,Gong Wenxue,Muhammad Yaseen,Shah Syed Jalil,Liu Qing,Xing Linguang,Zhou Xueyun,Liu Ying,Zhao Zhenxia,Zhao Zhongxing
A bimetallic polycrystalline sensor (Cr/Fe-SNCM) having nanosized and high dispersion was designed and used for the electrochemical simultaneous determination of dopamine (DA) and uric acid (UA). Catalytic nanosized Cr/Fe were highly anchored on N/S/O-contained porous carbon with high dispersion and polycrystalline Cr/Fe via energetic mechanochemical method and high-temperature carbonization. The obtained Cr/Fe-SNCM exhibited high graphitized carbon supporter and endowed high electron transport and signal output for the whole sensor. Moreover, highly dispersed Cr/Fe sites and the polycrystalline form (metal-N/S/O) efficiently enhanced the catalytic reaction, leading to a limits of detection (based on the 3σ/m criterion) of 25.8 and 22.5 nM for DA and UA, respectively. This is 1–2 orders of magnitude lower than many state-of-the-art reported sensors. The Cr/Fe-SNCM 1.0 sensor exhibited wide working range (0.1 to 10.0 μM), high recovery (96–103%) and low relative standard deviation (RSD = 3.2–4.7%) for DA and UA in real serum samples, possessing high significance for practical large-scale applications. Graphical abstract
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JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
·
2023
·
IF 4.3
Shiliang Zhu,Ke Li,Shuai Qin,Jianguo Lin,Ling Qiu
Traditional photodynamic therapy (PDT) suffers from poor tissue penetration due to using external light as excitation source. Cerenkov radiation (CR) from radionuclides can serve as an internal light source to activate photosensitizers inside lesion tissues. Using CR instead of external light in PDT is thought to be an effective way to overcome the shortcoming of traditional PDT. However, the weakness of CR emission limits the outcomes of CR-induced PDT (CR-PDT). We anticipated that CR-induced combined therapy could effectively enhance the therapeutic outcome of CR-PDT. Herein, a ROS-responsive Chemo-PDT agent ( TTC ) was synthesized by conjugation of tetraphenylporphyrin (photosensitizer) with camptothecin (chemotherapeutic drug) through a ROS-cleavable thioketal linker. Under activation by CR emission from gallium-68 ( 68 Ga), the porphyrin moiety could generate ROS , which then cleaves the thioketal linker to induce the subsequent release of CPT. Using [ 68 Ga]Ga-NOTA-Nb109 as an intracellular CR emitter, in comparison with its non-cleavable analogue ( TUC ) only displaying phototoxicity, TTC exhibited much higher cytotoxicity toward A375-hPD-L1 cells due to its combined effect of PDT and chemotherapy. Our work presents a new strategy to use ROS-responsive Chemo-PDT agent to improve the outcomes of CR-PDT.
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Environmental Science-Water Research & Technology
·
2023
·Vol. 9
·期 4
·1238-1253
·
IF 5
Xinling Wang,Chunhui Zhang,Zong Liu,Bingxu Quan,Wenjing Lu,Xuezhi Li,Peidong Su,Yuanhui Tang,Yuanqing Bu,Rong Zhou
Ceramic membrane separation has been widely used in industrial wastewater treatment, but membrane contamination problems have limited its efficient and economical application. This study introduced reduced graphene oxide (rGO) and carbon nanotubes (CNTs) into the preparation of polypyrrole (PPy). Both rGO and CNTs were loaded on the surface layer of a ceramic membrane by an in situ oxidative polymerization-self-assembly method to form an rGO–CNT–PPy modified ceramic membrane, which was supplemented with an electric field effect to improve the antifouling performance. Characterization and electrochemical analysis indicated that the modified conductive ceramic composite membrane exhibited excellent electrical conductivity and stability, with an average square resistance of 78.9 Ω sq−1. The experimental results showed that TN, COD, NH3-N, Ni, Fe, and Cu were well removed under certain conditions with a removal efficiency of 63.60%, 64.00%, 68.31%, 89.90%, 95.04%, and 88.82%, respectively. Meanwhile, the pH of pickling wastewater increased from 2.61 to 6.63, and the membrane contamination was significantly improved. Furthermore, after 5 runs, the decay of membrane flux was less than 12%, and this modified conductive ceramic composite membrane was subjected to an electric field, which can effectively slow down the membrane contamination phenomenon. This approach based on the rGO–CNT–PPy modified conductive ceramic membrane provides a clean and effective technique for membrane contamination control.
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ACS Applied Nano Materials
·
2023
·
IF 5.9
Xin Wang,Abing Guo,Yajun Fu,Mingyang Tan,Weiping Luo,Weijun Yang
Using pyrrole and terephthalaldehyde as raw materials, porphyrin-conjugated microporous polymer (CMP) without metal centers in the porphyrin ring was synthesized directly via the one-step method. The polymer was carbonized at different temperatures to obtain a series of carbonaceous nanospheres C-CMP-x (x is the pyrolysis temperature), of which C-CMP-900 is a multifunctional electrochemical catalyst with excellent performance. Compared to the uncarbonized polymer, C-CMP-900 is more sensitive and efficient for the reduction of nitrobenzene and exhibits a lower limit of detection. There was a significant improvement in the performance of nitrobenzene reduction over nonmetallic catalysts described in the literature. Moreover, the catalyst also shows excellent oxygen evolution reaction (OER) electrocatalytic activity, with lower overpotential than commercial RuO2. Even after long cycling tests, the catalyst maintained good activity. The catalyst, with an ultralow detection limit for nitrobenzene reduction and excellent OER activity, may be attributed to its high specific surface area and special porous carbon structure based on the porphyrin skeleton.
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JOURNAL OF POROUS MATERIALS
·
2023
·Vol. 30
·期 5
·1439-1448
·
IF 2.6
He Yan,Guo Zhulei,Chen Mingfan,Wan Sicheng,Peng Nan,Fu Xiaolei,Yuan Dingzhong,Na Bing
In this paper, a new type of carbazole-based hyper-crosslinked porous polymer (HCP-CP) was prepared through a very simple “knitted” method. The obtained novel polymer HCP-CP has a good adsorption property of methyl orange (MO) and methylene blue (MB) organic dyes in aqueous solution due to its high surface area and rich nitrogen atoms. The effect of pH, adsorption time, different initial concentration of dyes and adsorption reusability were investigated in detailed. The optimum pH is 8 for the adsorption of MB and 6 for the adsorption of MO, respectively. Under the best condition, the Langmuir model fitted the adsorption isotherm well and the adsorption behavior follow pseudo-second-order kinetics. The maximum adsorption capacity of HCP-CP for cationic dye MB (q max =751.88 mg/g) is more than twice higher than that of anionic dye MO (q max =274.73 mg/g). These capacity differences may be owing to the stronger electrostatic interaction between the negatively charged nitrogen atoms of HCP-CP with the cationic dye MB than that of MO. Moreover, the used polymer HCP-CP still retain a removal percentage above 92% after 5 times adsorption-desorption recycle. Therefore, this work provided a convenient synthetic route to develop a novel hyper-crosslinked polymer with high adsorption capacity for the entrapment of dyes from aqueous solution.
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POLYMER TESTING
·
2023
·
IF 5.1
Yanan Wang,Lijie Huang,Xiyue Wang,Xuyang Lu,Beiwei Wang,Yafei Qin,Chongxing Huang
Self-healing shape memory polymers (SMPs) have considerablepotential in advanced manufacturing and biomedical fields. Polypyrrole (PPy) exhibits excellent photoconversion properties, which may be utilized in SMP formulation; however, its application in this regard has not been explored. In this study, PPy-filled polymer nanocomposites were prepared to investigate their shape memory and self-healing characteristics. First, poly(lactic acid) (PLA) and polycaprolactone (PCL) were blendedto form PLA/PCL shape memory matrices. An 80:20 PLA/PCL blend showed excellent triple-shape memory performance with shape recovery rates ( R r 1 , R r 2 , and R r 3 R r ) of 92%, 87%, and 93%, respectively PPy nanoparticles were then incorporated into the blend as photothermal conversion fillers to develop photoresponsive SMPs. SMPs. The resulting PLA/PCL/PPy nanocomposites exhibited elevated surface temperatures during near-infrared (NIR) irradiation, thus demonstrating the photoconversion effect. In addition, these nanocomposites showed reversible triple-shape change behavior and excellent self-healing efficiencies upon NIR exposure, owing to the controllable melting and recrystallization of the PLA and PCL phases. Furthermore, the material properties of severed nanocomposites were restored after self-healing. These results, in addition to the biocompatibility and simple fabrication process of these materials, therefore demonstrate the potential utility of PPy-filled SMPs in several applications, including soft robotics and biomedical devices.
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ELECTROANALYSIS
·
2023
·Vol. 35
·期 5
·e202200298
·
IF 3
Rui Liu,Sai Zhang,Tianze Wang,Ningyan Hu,Xiao Ma,Liande Zhu
Nanostructured NiCu layered double hydroxides (NiCu LDHs) are synthesized in situ on polypyrrole nanotubes through convenient co-precipitation and hydrothermal synthesis. The nanostructured composite (NiCu LDHs/PPy) shows high electrocatalytic activities towards the glucose oxidation reaction in alkaline electrolyte so that a nonenzymatic glucose sensor is developed. It is demonstrated that the sensor offers a wide linear range from 1.5 μM to 1.0 mM with a high sensitivity of 525.8 μA mM −1 cm −2 and a low limit of detection of 66 nM (S/N = 3). The nonenzymatic sensor has been successfully applied to real blood samples for glucose monitoring with high accuracy.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2022
·
IF 9.965
Fuling Wang,Xue Liu,Binghan Jiang,Hongyan Zhuo,Wenmiao Chen,Yanli Chen,Xiyou Li
Reducing the loading of Pt precious metal is the promising pathway to positively promote the large-scale application for fuel cells and water electrolysis. In this work, a composite bifunctional electrocatalyst (named Pt@Fe SA -N-C) consisting of the atomically dispersed FeN 4 active sites and Pt nanoparticles (NPs) is successfully prepared for oxygen reduction reaction (ORR) and hydrogen evolution reactions (HER). In the process of synthesizing precursor of Pt(OH) 4 -Fe-Ppy@CNFs, the Fe-Ppy@CNFs was firstly prepared where the highly dispersed Fe 3+ ions were pre-anchored into polypyrrole (PPy) matrixes through in-situ polymerization on the surface of cellulose nanofibers (CNFs) and then Pt(OH) 4 nano-particles were deposited on Fe-Ppy@CNFs through adjusting the pH of the solution by urea hydrolysis to obtain the Pt(OH) 4 -Fe-Ppy@CNFs. Compared with the commercial 20 wt.% Pt/C, the obtained Pt@Fe SA -N-C possesses 5.5 wt.% low Pt loading. The strong synergistic effect of dual active sites between Pt NPs and FeN 4 on one-dimensional (1D) Fe SA -N-C support with a large surface area ensures effectively exposure of Fe and especial Pt active sites in the Pt@Fe SA -N-C. Both ORR and HER activities of the Pt@Fe SA -N-C were greatly improved in acid and alkaline media, even outperforming the commercial 20 wt.% Pt/C. Furthermore, the Pt@Fe SA -N-C shows an unordinary stability, with no obvious decrease in the current density after 5000 and 1000 cycles of accelerated durability tests (ADTs) for ORR and HER processes, respectively. This work highlights a preparation strategy for the synergistic effect between low-loading Pt precious metal and non-precious metals in electrocatalytic system.
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SYNTHETIC METALS
·
2022
·
IF 4
Yanhua Lei,Mengchao Ding,Haikun Wu,Di Yin,Yang Li,Bochen Jiang,Kai Sun,Yuliang Zhang,Hailiang Du
In this work, the layered Ti 3 C 2 T x MXene were coated with polypyrrole particles by an in-situ polymerization method, and their electromagnetic wave absorption performance were systematically studied. The MXene/PPy composites presented an excellent electromagnetic wave absorption performance, the strongest reflection loss can reach − 68 dB at 2.68 mm. Meanwhile, when the thickness is 2.26 mm, the effective absorption bandwidth can reach 6.56 GHz (from 11.44 to 18 GHz), covering the entire K u band (12–18 GHz). The multiple reflections at the heterogeneous interface, and the synergistic effect between the layered MXene and the conductive polypyrrole network made a combined effect on the optimized absorption. The MXene/PPy composites with a strong electromagnetic wave absorption, wide effective absorption bandwidth and corrosion resistance have a great value in aircraft and vessel fields.
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JOURNAL OF CHROMATOGRAPHY A
·
2022
·
IF 4.601
Xuejiao Xu,Lijin Huang,Qin Shuai
The ubiquitous occurrence of nonsteroidal anti-inflammatory drugs (NSAIDs) in the environmental water system has drawn significant concerns due to their adverse effects. The accurate monitoring the content of them is of great significance but challenging in terms of the complex matrix and trace concentration. In this work, a porphyrin-based magnetic porous organic polymer composite (PM-POP) was prepared through a solvent-free synthetic method. Owing to the highly porous structure and strong affinities, the as-prepared PM-POP could be utilized as a highly efficient adsorbent for the magnetic solid phase extraction (MSPE) of NSAIDs. Combining with the high-performance liquid chromatography separation with ultraviolet detector (HPLC-UV), a sensitive analytical method was established, which exhibited wide linear ranges (0.1–400 μg/L) and large enrichment factors (EFs) (39.5–82.9 folds) along with good precision (intra-day RSD ≤ 4.9%) and repeatability (inter-day RSD ≤ 8.4%). Ultimately, it was applied to determinate trace NSAIDs in practical water samples successfully, demonstrating its good application prospect in environmental analysis.
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