TURKISH JOURNAL OF CHEMISTRY
·
2022
·Vol. 45
·期 4
·1133-1145
·
IF 1.151
WANG DING-KAI,ZHAO WEI,CUI MING-YU,GUO TIAN-TIAN,FU SHUI-YUAN,LI WEI-GANG
A series of Zr(SO4)2/SiO2 solid acid catalysts with different Zr(SO4)2 loadings were prepared by water-soluble-impregnation method at room temperature. Then, the prepared catalysts were characterized by Fourier transform infrared spectroscopy, transmission electron microscopy and energy-dispersive X-ray spectrum, X-ray diffraction, adsorption/desorption of N2, and temperature-programmed desorption of NH3. The results showed that the active component Zr(SO4)2 was successfully adhered to the mesoporous SiO2, and the acid amount of Zr(SO4)2/SiO2 increased with the increasing of the Zr(SO4)2 loadings. Finally, the wheat stalk was used as raw material and depolymerized over Zr(SO4)2/SiO2 to produce ethyl levulinate (EL). The reaction mixture was separated and purified by filtration and vacuum distillation. The kinetic characteristics and the reaction pathway were also studied. A comparative study showed that 20 wt.% Zr(SO4)2/SiO2 exhibited higher catalytic activity. When reaction temperature, time, catalyst dosage and Zr(SO4)2 loadings were 190 °C, 50 min, 20 wt.% and 30 wt.%, the EL yield reached a maximum of 17.14%. The relative content of EL exceeded 90% after three steps of distillation.
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CHEMISTRY & BIODIVERSITY
·
2026
·Vol. 23
·期 6
·e71440
·
IF 2.9
Qun Wang,Shaoyan Shuang,Shaobin Xu,Huilu Sun,Jiaxuan He,Yuee Tian,Xiaobo Huang,Genqiang Chen,Zhiping Che
In order to discover highly bioactive Fenjuntong compounds, 10 2′-acyloxyfenjuntong derivatives ( 3a – j ) were synthesized by structural modification of Fenjuntong, and their structures were well characterized by 1 H NMR, 13 C NMR, and HRMS. Furthermore, the bioactivities of these compounds as anti-oomycete, antifungal, and nematicidal agents against three serious agricultural pests, Phytophthora capsici , Fusarium graminearum , and Heterodera glycines were evaluated. Among all tested compounds, first, compound 3a exhibited promising anti-oomycete against P. capsici , with an EC 50 value of 35.00 mg/L. Second, compounds 3d and 3f displayed promising antifungal against F. graminearum , with EC 50 values of 52.60 and 39.41 mg/L, respectively. Third, compounds 3g , 3i , and 3j showed significant nematicidal activity against H. glycines , with LC 50 values of 36.29, 30.19, and 35.43 mg/L, respectively. The results demonstrate that introducing acyloxy pharmacophores at the phenolic hydroxyl position of Fenjuntong not only significantly enhances its biological activity against P. capsici , F. graminearum , and H. glycines , but also yields target compounds that uniformly more active than Fenjuntong itself. Moreover, these important results lay the foundation for further optimization of Fenjuntong toward the development of potential new pesticides. Graphical
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2026
·Vol. 74
·期 32
·25119-25128
·
IF 6.7
Li Biao,Ying Rui-Ning,Wang Xian-Quan,Zhao Jing,Lin Hong-Yan,Wang Da-Wei,Yang Guang-Fu
4-Hydroxyphenylpyruvate
dioxygenase (HPPD) has become an attractive
target for herbicide development owing to the slow development and
low risk of resistance to its inhibitors. However, most available
HPPD inhibitors exhibit limited crop selectivity and poor efficacy
against grasses. Therefore, the exploration of novel molecular scaffolds
is of great research value. In this study, we adopted a ring-fusion
strategy to enhance π–π stacking interactions and
developed a structurally novel pyrazole-4-chloro-benzimidazolin-2-one
scaffold. Through systematic structural optimization, compound II-19 showed the strongest enzyme inhibitory activity, with
an IC 50 of 52 nM, about 6-fold higher potency than the
positive control, mesotrione. The crystal structure of At HPPD- II-19 revealed that the inhibitor engages in characteristic
chelation and π–π stacking interactions within
the active site, and the 3-NO 2 -benzyl group contributes
additional hydrophobic interactions and a possible weak water-mediated
interaction involving Gln293. Additionally, I-5 showed
excellent broad-spectrum weed control and good safety toward peanut
at 30 g a.i./ha. These results indicate that compound I-5 is a promising candidate for the development of new HPPD inhibitors
for weed control in peanut fields.
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2023
·
IF 7.2
Hui Zhang,Qiang Fu,Hongyun Qin,Xia Chen,Qicheng Zhang,Zixu Dong,Haoyuan Li,Shoudong Wang,Ming Wang
Hydrogen recovery from ammonia purge gas is a desirable method to relieve the pressure of increasing demand for hydrogen. Metal-organic frameworks (MOFs) are promising adsorbents for the separation of the H 2 –N 2 mixture. However, the separation of the H 2 –N 2 mixture using MOFs remains challenging due to the lack of adsorptive mechanism. Herein, the adsorption mechanism of the H 2 –N 2 mixture in SIFSIX-2-Cu-i has been systematically investigated with the method of a combination of excess adsorption experiments, molecular simulations , and DFT calculations. In the Grand Canonical Monte Carlo (GCMC) simulations, the polarizable force field was first applied to the adsorption of pure H 2 or N 2 and H 2 –N 2 mixture in SIFSIX-2-Cu-i. Ab Initio Molecular Dynamics (AIMD) was performed to investigate the distribution of the guest molecules in the pores of SIFSIX-2-Cu-i. Finally, Density functional theory (DFT) calculations were performed to predict the transfer of charge between MOF and guest molecules. Results revealed two binding sites of H 2 or N 2 in SIFSIX-2-Cu-i. A relatively high thermodynamic adsorption selectivity for N 2 over H 2 has been observed in SIFSIX-2-Cu-i. Furthermore, SIFSIX-2-Cu-i also exhibits a greater affinity with N 2 than with H 2 , which is probably because of the stronger induction interactions between F2 atoms and N 2 molecules. These findings are of significance to guide the design of the new highly selective adsorbents for the separation of H 2 /N 2 .
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CONNECTIVE TISSUE RESEARCH
·
2023
·
IF 2.9
Gao-Feng Zhao,Le-Bin Huang
Aims Osteoarthritis (OA) is a chronic inflammatory disease, characterized by degradation of extracellular matrix, apoptosis of chondrocytes and inflammation in articular cartilage. Zinc finger E-box binding homebox 2 (ZEB2), a transcription repressor, has been demonstrated with anti-inflammatory role in some cells. The analysis from GEO data reveals that ZEB2 expression is upregulated in articular cartilage of OA patients and experimental OA rodents. This study aims to confirm the function of ZEB2 in OA process.Material and methods The experimental OA was induced by anterior cruciate ligament transaction (ACLT) in rats, and the adenovirus loaded with ZEB2 coding sequence was intra-articularly injected into rats (1 × 10 PFU). The primary articular chondrocytes were stimulated by interleukin-1β (IL-1β) (10 ng/ml) to mimic the osteoarthritic injury, and transfected with the adenovirus carrying ZEB2 coding or silencing sequence. The apoptosis, content of extracellular matrix, inflammation, and the activity of NFκB signaling in chondrocytes and cartilage were determined.Results ZEB2 was highly expressed in osteoarthritic cartilage tissues and IL-1β-treated chondrocytes. The overexpression of ZEB2 restrained ACLT- or IL-1β administration-induced apoptosis, matrix degradation and inflammation in vivo or in vitro, evidenced by changed levels of cleaved caspase-3/PARP, collagen-II, aggrecan, matrix metalloproteinase 3/13, tumor necrosis factor-α and interleukin-6. Additionally, the phosphorylation of NFκB p65, IκBα and IKKα/β, and the nuclear translocation of p65 was blocked by ZEB2, implying inactivation of this signaling.Conclusions ZEB2 mitigated osteoarthritic symptoms in rats and chondrocytes, and NFκB signaling might be involved. These findings may provide novel insights for clinical treatment of OA.
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JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
·
2023
·Vol. 148
·期 13
·6133-6150
·
IF 4.4
Zhao Jihe,Hu Jiwen,Dong Yonglu,He Daguang,Gui Xuefeng,Cui Xiaohua,Tu Yuanyuan,Lin Shudong
Thermal runaway accidents have occurred mainly during storage and transportation of azo compounds because large amounts of heat were released during the course of thermal decomposition. In this study, the thermal runaway characteristics of 2,2′-azobis(2-methylbutyronitrile) (AMBN) were first comprehensively investigated via differential scanning calorimetry (DSC), accelerating rate calorimetry (ARC), and gas chromatography/mass spectrometry (GC-MS). The onset temperature ( T on ), heat of decomposition ( Q ), and adiabatic temperature rise (Δ T ad ) were determined, which were involved in the safety of storage and transportation. Corresponding thermokinetic analyses were performed using DSC and ARC data. The data obtained from the experiments and calculation were utilized to predict the self-accelerating decomposition temperature (SADT), the control temperature ( T NR ), and the emergency temperature ( T C,I ). In addition, the flammable components in the pyrolysis products of AMBN were studied, particularly mixed with incompatible materials, such as HCl, NaOH, and Fe 2 O 3 , which helped predict the risk of thermal runaway during storage and transportation. Graphical Abstract
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ACS Applied Materials & Interfaces
·
2023
·
IF 9.5
Chaohua Sun,Rui Miao,Jipeng Li,Yanzhi Sun,Yongmei Chen,Junqing Pan,Yang Tang,Pingyu Wan
Aqueous zinc-ion batteries are considered as an ideal substitute for lithium-ion batteries due to their abundant resource storage, high safety, and low price. However, zinc anodes exhibit poor reversibility and cyclic stability in most conventional aqueous electrolytes. Herein, an environmentally friendly Zn(CH3SO3)2 electrolyte is proposed to solve the problems of common aqueous electrolytes. The bulky CH3SO3– anions can regulate the solvation structure of Zn2+ by replacing some water molecules in the primary solvation sheath of Zn2+, thus slowing the hydrogen evolution side reactions and formation of zinc dendrite. Additionally, the changing solvation structure weakens the bonding between Zn2+ and the surrounding water molecules, which is conducive to the transport and charge transfer of Zn2+, thus improving the battery capacity. In the Zn(CH3SO3)2 electrolyte, Zn plating/stripping exhibits a high Coulombic efficiency of >98% and long-term cyclic stability over 800 h. The specific capacity of the assembled Zn//V2O5 cell in 3 mol L–1 Zn(CH3SO3)2 reaches 350 mA h g–1 at 0.1 A g–1, much higher than that in the ZnSO4 electrolyte (213 mA h g–1). In conclusion, this work offers insights into the exploration of advanced green electrolyte systems for zinc-ion batteries.
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高影响因子
Small
·
2023
·Vol. 19
·期 20
·2208167
·
IF 13.3
Mengya He,Xican Xu,Hongyu Wang,Qingyuan Wu,Linghao Zhang,Dongsheng Zhou,Yigang Tong,Xin Su,Huiyu Liu
Fluorescence-based PCR and other amplification methods have been used for SARS-CoV-2 diagnostics, however, it requires costly fluorescence detectors and probes limiting deploying large-scale screening. Here, a cut-price colorimetric method for SARS-CoV-2 RNA detection by iron manganese silicate nanozyme (IMSN) is established. IMSN catalyzes the oxidation of chromogenic substrates by its peroxidase (POD)-like activity, which is effectively inhibited by pyrophosphate ions (PPi). Due to the large number of PPi generated by amplification processes, SARS-CoV-2 RNA can be detected by a colorimetric readout visible to the naked eye, with the detection limit of 240 copies mL −1 . This conceptually new method has been successfully applied to correctly distinguish positive and negative oropharyngeal swab samples of COVID-19. Colorimetric assay provides a low-cost and instrumental-free solution for nucleic acid detection, which holds great potential for facilitating virus surveillance.
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2022
·
IF 7.139
Yuyu Li,Fang Luo,Yuhua Xie,Chaofeng Chang,Ming Xie,Zehui Yang
Urea oxidation reaction (UOR) is a promising substitution of oxygen evolution reaction (OER) in overall water splitting technology because of the lower theoretical potential; thereby, a win-win benefit is achieved due to the simultaneous hydrogen generation and water purification . The efficient UOR catalysis substantially depends on the exposed active sites and mass transfer resistance, especially at high current density to meet the requirement of industrial water splitting technology. In this work, we have synthesized α-Ni(OH) 2 porous nanoflowers (α-Ni(OH) 2 –PNF) using ZIF-67 as template. Ascribing to the Kirkendall effect , nanopores are created on α-Ni(OH) 2 nanosheets benefiting for the formation of abundant oxygen vacancies as well as drop-off in mass transfer resistance during UOR catalysis. Meanwhile, the binding strength between active site and CO 2 , rate-determining step of UOR, is weakened by oxygen vacancies; as a result, only 1.477 V vs. RHE is demanded for α-Ni(OH) 2 –PNF to catalyze UOR with 100 mA cm −2 , 67 mV lower than α-Ni(OH) 2 nanosheets. Besides, an exceptional stability is also achieved for α-Ni(OH) 2 –PNF with negligible degradation during 20 h catalysis.
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FOOD CHEMISTRY
·
2022
·
IF 9.231
Lihong He,Can Zeng,Lingfeng Wei,Li Xu,Fenglin Song,Jianrong Huang,Nanjing Zhong
This study aims to fabricate immobilized lipases for efficient preparation of 1,3-dioleoyl-2-palmitoyl-glycerol (OPO) through acidolysis of glycerol tripalmitate (PPP). Twelve (three types) supports and five lipases were studied carefully. Among them, the immobilized Thermomyces lanuginosa lipase (TLL) samples exhibited overall better performance than that of other immobilized lipases. Particularly, organic groups functionalized SBA-15 (R-SBA-15) supported TLL (TLL@R-SBA-15) samples gave PPP conversion from 97.70 to 99.00 % and OPO content from 59.52 to 64.73 %. After optimization, PPP conversion up to 99.07 %, OPO content 73.15 % and sn -2 palmitic acid content 90.09 % were obtained with TLL@C 18 H 37 -SBA-15 as catalyst. Moreover, TLL@C 18 H 37 -SBA-15 exhibited better acidolysis performance from 50 °C than that from 60 to 80 °C, which helped inhibit acyl migration. In addition, after 5 cycles of reuse, TLL@C 18 H 37 -SBA-15 retained 81.04 % (based on OPO content) and 98.88 % (based on sn- 2 palmitic acid content) of its initial activity, indicating it had an attractive prospect in future applications.
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FUEL
·
2022
·
IF 8.035
Hua Yan,Xiaowei Liu,Junhong Zhou,Dawei Li,Xiaoye Yang,Yiming Gu,Hongjiu Su,Shudong Wang
The development of anthraquinone (AQ) hydrogenation catalysts with high activity and selectivity remains a challenge, but it is critical in industrial applications from both economic and environmental perspectives. In this work, an amine-modified catalyst, i.e., Pd/A/SiO 2 , was designed and synthesized via grafting 3-aminopropyltrimethoxysilane (APTMS) onto silica support and then loading Pd via the Shiff-base reaction. Multiple techniques were used to thoroughly characterize and analyze the catalysts' structural and electronic properties, such as transmission electron microscopy (TEM), H 2 temperature-programmed reduction (H 2 -TPR), and X-ray photoelectron spectroscopy (XPS), etc. The Pd particle size (3.86 nm) in Pd/A/SiO 2 was found to be very close to the reported optimal value, which balances well between the number of active sites and the required size for AQ adsorption; also, the residual carbon species from APTMS improves the hydrophobic properties of the support, which benefits AQ adsorption and anthrahydroquinone (AQH 2 ) desorption; and furthermore, the electron transferred from N to Pd increases the electron density of the latter, favoring the activation of the C O bond in AQ. These factors combine to give a very superior performance of Pd/A/SiO 2 for AQ hydrogenation, including a hydrogenation efficiency as high as 15.7 g/L with an intriguing selectivity of 96.1 %, and a good reusability merit within a six-run test, all of which are among the best results reported so far. This work, we believe, provides food for thought in the development of a highly efficient catalyst for AQ hydrogenation.
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JOURNAL OF ORGANOMETALLIC CHEMISTRY
·
2023
·
IF 2.3
Lin Tan,Ce Xu,Zhen Li,Yirong Wang,Xianghong Li,Bingguang Zhang
A cyclometalated ruthenium complex ( 1 ) with 2-phenylbenzimidazole as the ligand was synthesized and used as a colorimetric chemosensor to detect Hg 2+ and Cu 2+ . It is interesting that the presence of Hg 2+ caused a blue-shifted absorption of 1 from 560 to 450 nm resulting in a solution color change from red to yellow, while the addition of Cu 2+ resulted in an attenuated absorption along with the solution color changing from red to colorless. Their corresponding detection limits were calculated to be 0.25 µM for Hg 2+ and 0.45 µM for Cu 2+ , respectively. Moreover, the slips of paper were dyed with complex 1 and then successfully used to recognize Hg 2+ and Cu 2+ by naked eyes, respectively. Furthermore, 1 was also used to determine Hg 2+ and Cu 2+ in some spiked water samples, respectively.
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