Journal of Food Measurement and Characterization
·
2022
·Vol. 16
·期 5
·3438-3450
·
IF 3.006
Liu Yan,Wang Chao,Xia Zhenzhen,Wang Qiao,Duan Shuo
A method for monitoring the freshness of crayfish by near-infrared spectroscopy combined with chemometrics was proposed in this study. The total volatile basic nitrogen (TVBN), K value and biogenic amine were adopted as the indexes of freshness. The 120 peeled and the 120 whole tail samples were utilized to build the quantitative models by partial least squares (PLS) regression, respectively. The spectral pretreatment and the variable selection methods were adopted to further improve the models. For the models of TVBN and K value, the combination of continuous wavelet transform (CWT) and randomization test (RT) method could improve the predictability effectively. The combination of 1st derivative and RT method could get better results for the optimization of the biogenic amine models. The optimized models were evaluated by 40 peeled and the 40 whole tail samples, and then utilized to predict the three indexes in another 32 peeled tails and 40 whole tail samples for practical application. Reasonable results were obtained for the samples with TVBN levels ranging from 28.01 mg/kg to 284.89 mg/kg, K value levels ranging from 13.04 to 87.36% and biogenic amines ranging from 148.57 mg/kg to 663.71 mg/kg. For the TVBN, K value and biogenic amine in the 32 peeled tail samples, the correlation coefficients between the results calculated by the optimized models and those measured by the standard methods were 0.95, 0.94 and 0.96 respectively. As to the three freshness indexes in 40 whole tail samples, the correlation coefficients were 0.95, 0.93 and 0.94, respectively.
研究领域:
食品科学
·
光谱学
·
化学计量学
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高影响因子
ACTA PHARMACOLOGICA SINICA
·
2024
·
IF 6.9
Hu Cheng-hong,Chen Yue,Jin Tian-yang,Wang Zhe,Jin Bo,Liao Jing,Ding Chun-yong,Zhang Ao,Tang Wei-yang,Zhang Ling-xi,Xu Lei-yu,Ning Fang-min,Liang Guang,Wei Xiao-hong,Wang Yi
Inflammatory bowel diseases (IBDs) are chronic inflammatory conditions primarily affecting the gastrointestinal tract. Previous studies established the role of the NF-κB signaling pathway in the development of IBDs, suggesting that anti-inflammatory therapies might offer a viable treatment strategy. Tanshinone IIA and salviadione, both derived from Salviae Miltiorrhizae Radix et Rhizoma , possess anti-inflammatory and anti-oxidative activities. A series of new compounds were synthesized by hybridizing salviadione with tanshinone. Among these compounds, 15a showed beneficial effects in LPS-induced acute lung injury and diabetes-induced renal injury mouse models. The current study explored the therapeutic efficacy of 15a using both acute and chronic colitis models and elucidated the underlying mechanisms. DSS-induced colitis models were established in mice, where acute colitis was treated with compound 15a (5 or 10 mg·kg −1 ·d −1 ) for 8 days, while chronic colitis mice received compound 15a (5 or 10 mg·kg −1 ·d −1 , i.g.) during 2.5% DSS administration. The 15a treatment significantly alleviated DSS-induced pathological and inflammatory damages in both acute and chronic colitis mouse models. In mouse intestinal epithelial cell line MODE-K, pretreatment with compound 15a (5 or 10 μM) significantly suppressed LPS + L18-MDP-induced inflammatory responses. The receptor-interacting serine/threonine kinase 2 (RIPK2) was identified as a direct binding target of compound 15a using microarrays and recombinant human proteins. Moreover, 15a could directly bind to and inhibit the phosphorylation of RIPK2, leading to the suppression of the NF-κB and MAPK signaling pathways. Furthermore, LEU153 and VAL32 were identified within the KD domain of RIPK2 as critical amino residues for the binding of 15a. Briefly, the current findings demonstrate that compound 15a holds promise as a therapeutic agent for managing acute and chronic colitis.
研究领域:
药理学
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免疫学
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胃肠病学
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炎症性肠病
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分子生物学
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DOI
PubMed
高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2025
·
IF 2.1
Jingli Sun,Xuqiang Li,Lu Chen,Yujie Zhen,Siyu Zheng,Shaolong Dong,Yingmin Yu
In order to reduce the impact of nitrogen-containing compounds in oil products on the environment, this paper selected n-heptane as the oil product model and pyridine as the nitrogen-containing compound. Four inexpensive extractants (furfuryl alcohol, 1,4-butanediol, N,N-dimethylacetamide, and dimethyl sulfoxide) were selected as the extractants to separate pyridine from the oil model at 303.2 K, and the liquid–liquid equilibrium (LLE) data were measured. The partition coefficients (D) and separation coefficients (S) of the extractants were calculated and used to evaluate the extractants. Based on the LLE data, correlations were performed using NRTL and UNIQUAC models, and the interaction parameters of the corresponding optimization models were obtained. The root-mean-square deviation (RMSD) values of the NRTL and UNIQUAC models were 0.98% and 1.09%, respectively. The GUI-MATLAB tool was selected to evaluate the accuracy of the binary interaction parameter regression by a Gibbs energy topology analysis. To probe the underlying mechanism of the extraction process between the extractants and pyridine, the σ-profile was used to analyze the interaction patterns between the extractants and pyridine. Given their high extraction efficiency, the studied extractants can be considered as potential extractants for extractive denitrification processes.
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产品关联
DOI
高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2025
·
IF 2.1
Yu Bi,Xiao chen Ye,Jingwen Zhang,Ziyin Wang,Zenan Gong,Yanmin Shen,Wenju Liu
In the study, the experiment solubility of difenidol hydrochloride was determined in 12 neat solvents [water, methanol, ethanol, n-propanol, n-butanol, 1-pentanol, N-methyl-2-pyrrolidone(NMP), N,N-dimethylformamide(DMF), N,N-dimethylacetamide (DMA), dimethyl sulfoxide (DMSO), acetonitrile (MeCN), and acetic acid] at a temperature range from 278.15 to 323.15 K by a gravimetric method under 0.1 MPa. Results indicated that the experimental mole fraction solubility (10x) order of difenidol hydrochloride in 12 neat solvents at the temperature 298.15 K was: methanol(0.1771)>DMSO(0.1343)>NMP(0.0725)>acetic acid (0.0601)>DMF(0.0467)>DMA(0.0357)>ethanol (0.0336)>n-propanol (0.0255)>n-butanol (0.0137)≈water (0.0135)>1-pentanol (0.0098)>MeCN (0.0041), and solubility increased with the increase in temperature. Three models, including Modified Apelblat model, Van’ t Hoff model, and Yaws model, were applied to correlate the experimental data and analyze the solubility data of difenidol hydrochloride. Based on the principle of similar compatibility, the law of solubility and miscibility of difenidol hydrochloride in selected solvents was discussed according to Hansen solubility parameters (HSP) and solvent effect for predicting solubility behavior.
研究领域:
药物化学
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热力学
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溶解度工程
·
化学工程
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产品关联
DOI
高影响因子
Additive Manufacturing
·
2025
·
IF 11.1
Junli Liu,Shipeng Zhang,Lucen Hao,Bo Wu,Kaiyin Zhao,Chi Sun Poon
Carbon dioxide (CO 2 ) has been increasingly applied to modify the fresh and rheological properties of cement mortars and concrete, enhancing the mortars’ mechanical properties through CO 2 capture. For 3D printing, most research has adopted the 1 K (one-component) printing system for CO 2 -integrated cement mortar prepared by batch mixing. In contrast, limited work has been conducted on mortars subjected to CO 2 flash mixing in the 2 K (two-component) system, where pumped fresh mortar was mixed with continuously injected CO 2 within a timeframe of seconds during secondary mixing. In this paper, we report the development of a novel low-carbon cement mortar mixture consisting of ordinary Portland cement (OPC), ground granulated blast furnace slag (GGBS) and calcium hydroxide (CH) in binders that exhibited instant change in rheological properties and rapid stiffening when subjected to CO 2 flash mixing. The rheological properties of the CO 2 -mixed mortar improved with increasing proportions of GGBS and CH in the mortar mix. In-situ chord length measurements suggested that the improved rheological properties of the mortar after CO 2 flash mixing were related to the rapid growth of fine CaCO 3 crystals, driving subsequent particle flocculation. The instant flocculation was primarily attributed to electrostatic attraction between particles with opposite surface charges in the OPC-GGBS-CH system induced by CO 2 flash mixing.
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高影响因子
JOURNAL OF CATALYSIS
·
2025
·
IF 6.5
Yusen Li,Xiaobin Hou,Xitong Ren,Yajie Tian,Jiajie Sun,Feng Bai,Y. Li,X. Hou,F. Bai
The integration of dual active sites for concurrent oxygen reduction (ORR) and water oxidation (WOR) within a single covalent organic framework (COF) remains a fundamental challenge in the artificial photosynthesis of H 2 O 2 . To address this, we report a positional isomerization strategy that precisely engineers the substitution sites on a pyrene core, constructing four isomeric pyrene-based COFs (A-Py-COF, KA-Py-COF, AK-Py-COF, and K-Py-COF). Structure-activity studies reveal that K-region substitution is pivotal in activating the framework for efficient stepwise two-electron ORR and two-electron WOR. As a result, the optimized K-Py-COF achieves a remarkable photocatalytic H 2 O 2 production rate of 468.3 μ mol g –1 h −1 in pure water without sacrificial agents, representing a 7.8-fold enhancement over its A-Py-COF analogue. In a biphasic water-benzyl alcohol system, the H 2 O 2 production rate of K-Py-COF increases dramatically by 15.3 times, a performance that surpasses most state-of-the-art metal-free COF photocatalysts. By establishing a clear correlation between molecular isomerism and the localization of redox-active sites, this work provides a novel design principle for developing dual-channel COFs toward sustainable H 2 O 2 synthesis.
研究领域:
材料科学
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光催化
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可持续化学
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有机框架
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能量转换
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DOI
高影响因子
FLUID PHASE EQUILIBRIA
·
2025
·
IF 2.7
Yanyan Hou,Zhentao Zhang,Ziyue Zhang,Yi Yu,Li Xu
The solubility of glutaric anhydride (GA) in ten single organic solvents containing methyl acetate, ethyl acetate, n -propyl acetate, butyl acetate, acetone, acetonitrile, dichloromethane, 1,2-dichloroethane, DMF, DMAC, was determined by static method. In the experimental temperature range (278.15 ∼ 313.15 K), the solubility of the measured GA in each solvent increased with the increase of temperature. Among the solvents selected, GA had the highest solubility in DMAC and the lowest solubility in butyl acetate. The solubility of GA in DMAC was about 2 ∼ 3 times higher than in butyl acetate. Solvent effects in different solvents were explained by the Hansen solubility parameter (HSP) and the physicochemical properties of the solvents (polarity, hydrogen bond donor-acceptor tendency, and cohesion energy density). The analysis of solvation effect showed that the changes of GA solubility were the results of the combined effect of multiple factors, among which the effect of solvent polarity was more significant. Based on density functional theory (DFT), the electrostatic potential energy surface and solute-solvent interaction of GA were analyzed at the molecular level. In addition, the solubility data were fitted using the van't Hoff, modified Apelblat, Yaws, λh and Wilson models. The fitting results showed that the Yaws model had the best correlation with the smallest ARD (3.74%) and RMSD (0.82%). The analysis results of the apparent thermodynamic properties indicated that GA dissolution was a spontaneous, endothermic, entropy-driven process.
研究领域:
物理化学
·
热力学
·
溶液化学
·
化学工程
·
分子模拟
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产品关联
DOI
高影响因子
Journal of Materials Chemistry C
·
2017
·Vol. 5
·期 47
·12422-12429
·
IF 5.256
T. T. Deng,E. H. Song,Y. Y. Zhou,L. Y. Wang,Q. Y. Zhang
Three isotypic double perovskites A2BAlF6:Mn4+ (A = Rb, Cs; B = K, Rb) were synthesized via a facile co-precipitation method at room temperature. XRD Rietveld refinements and Raman spectra indicate that the neighboring smaller A-site or larger B-site cation in A2BAlF6:Mn4+ lowers structural stability, but suppresses the [AlF6] octahedron to increase the crystal field strength and bond strength of the Al–F bond. Cs2KAlF6:Mn4+ presents a sharp line red light and excellent moisture resistance, but experiences severe thermal quenching. In comparison, altering the A- or B-site cation to Rb, Rb2KAlF6:Mn4+ and Cs2RbAlF6:Mn4+ shows blue shifts in emission and declining water resistance, but enhancements in thermal stability. A combination of static and dynamic emission degradations demonstrates that the water resistance of Mn4+ emission mainly relies on the structural stability of the host matrix; meanwhile, the thermal stability highly depends on the rigidity of its local accommodation. The variations of the temperature-dependent white light-emitting diode (WLED) performances further evidence their sufficient thermal stability for LED applications. These findings suggest that neighboring-cation modulation might be a feasible guideline for exploiting stable Mn4+-activated fluoride red phosphors in warm WLED applications.
研究领域:
材料科学
·
光学
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DOI
高影响因子
JOURNAL OF CHEMICAL THERMODYNAMICS
·
2022
·
IF 3.269
Song Lin,Mingyi Xu,Mai Han,Houchun Yan,Yufan Pang,Qingsong Li
The liquid–liquid equilibrium (LLE) data of water + 1,2-Dimethoxyethane (DME) + {isopropyl ether, 1-hexanol, n-heptanol and 4-methyl-2-pentanol (MIBC)} was measured at 303.2 K under 101.3 kPa. The distribution coefficient (D) and selectivity factor (S) based on the experimental data were calculated, and use this to evaluate the extraction effect of the four solvents. Using two thermodynamic models of NRTL and UNIQUAC to fit the experimental data, and obtained the binary interaction parameters. The root means square deviation (RMSD) of the fitting results were all less than 0.75%. The GUI-MATLAB tools were applied to verify the consistency of the binary interaction parameters.
研究领域:
化学工程
·
物理化学
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DOI
高影响因子
Carbon Neutralization
·
2024
·Vol. 3
·期 6
·1131-1139
·
IF 0
Ling Bai,Su Jin,Qian Liu,Wenjuan Xu,Ziquan Li,Zhen-Dong Huang
Searching for low-cost, high-capacity, high-power, high-stability, high-tap-density, and inherently safe materials for developing cheap, safe, and high-performance batteries has always been a research hotspot. Herein, an inherently safe, low-cost, and low-strain KTiOPO 4 (KTOP) submicron single crystals with a uniform thin layer carbon coating are developed using a ball-mill assisted solid-state method. Uniform solid electrolyte interphase, carbon coating, and inherently stable structure synergistically help compact KTOP submicron single crystals achieve an exceptional anodic K-ion storage performance. The carbon-coated KTOP single crystals obtained under the carbonization temperature of 400°C (KTOP-C-400) can deliver an exceptional potassium ion storage performance of 253.3, 224.0, 175.5, and 131.1 mA h g −1 at the current density of 100, 200, 500, and 1000 mA g −1 , respectively, in the electrolyte of 5 M potassium bis(fluorosulfonyl)imide (KFSI) in DIGLYME electrolytes. Even after being cycled at 1000 mA g −1 for 1000 cycles, the capacity was maintained at 182.5 mA h g −1 with a coulombic efficiency of 99.9%.
研究领域:
材料科学
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储能
·
电化学
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电池技术
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DOI
Materials Advances
·
2022
·Vol. 3
·期 15
·6171-6178
·
IF 0
Mingsheng Cai,Tianchun Lang,Tao Han,Damir Valiev,Shuangqiang Fang,Houjiang You,Bitao Liu,Ling Du,Zichao Xu,Elena F. Polisadova
Investigating narrow-band green emitting phosphors with high efficiency and good thermal stability is the main goal of the present light-emitting diode (LED) display research. Here, Ba1−xCaxScO2F:0.001Bi3+,0.001K+ (x = 0–0.12) perovskite phosphors, emitting narrow green light excited by a 415 nm chip, were developed using the cation substitution design strategy. The effects of Ca2+ substitution for Ba2+ in the Ba1−xCaxScO2F:0.001Bi3+,0.001K+ crystal structures and photoluminescence properties were investigated. All the phosphors show the cubic perovskite-type structure in the space group Pm3m. The evolution of the cell parameters and the Ba/Ca/K/Bi–O bond lengths were evaluated. The phosphors with the internal quantum efficiency of 77.4% exhibit bright green emission peaking at 510 nm under 415 nm chip excitation. The improvement of luminescence efficiency and thermal stability was discussed in detail in relation to the local structure variation. The cation substitution design strategy mentioned here can become an important approach to realize the spectral modulation through controlling the micro-environment in the lattice for excellent LED backlight displays.
研究领域:
材料科学
·
光学工程
·
无机化学
·
固体物理
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显示技术
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DOI
JOURNAL OF MOLECULAR LIQUIDS
·
2019
·
IF 4.561
Hui Guo,Yu Dong,Tiantian Ping,Xiaoqin Shi,Shufeng Shen
Densities and viscosities for the binary liquid mixtures of monoethanolamine (MEA) with 2-alkoxyethanols (2-ethoxyethanol (EGEE) and 2-butoxyethanol (EGBE)) were measured over the entire concentration range at temperatures of 293.15–353.15 K and atmospheric pressure. From the experimental results, the excess molar volume ( V E ), viscosity deviations (∆ η ) and excess Gibbs free energy of activation of viscous flow (∆ G ⁎E ) were calculated and the excess/deviations properties for the studied binary systems were fitted with the Redlich-Kister equation to estimate the binary interaction parameters. The results were analyzed in terms of intermolecular interactions between unlike molecules and intramolecular interactions within like associated molecules. The densities and viscosities of CO 2 -loaded solutions were also measured and correlated with the proposed correlations. The calculated values of density and viscosity for the binary/ternary systems are in good agreement with the experimental values, with AADs within 0.2% for density and 3.2% for viscosity. The FTIR spectral analysis for the binary mixtures of MEA with 2-alkoxyethanols at various concentrations suggests the presence of weak interactions between component molecules in the systems, and also supports the findings of excess properties.
研究领域:
物理化学
·
分子相互作用
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DOI
高影响因子
危险品化学品经营许可证（带存储）