JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2016
·
IF 3.782
Tingting Zhao,Xin Liu,Yuebin Li,Mingguang Zhang,Jian He,Xuewen Zhang,Hui Liu,Xingguo Wang,Haoshuang Gu
Hydrophobic ZnSe:Mn/ZnS core-shell fluorescence quantum dots (QDs) and anticancer drug paclitaxel (PTX) have been co-loaded into folate conjugated hybrid silica nanocapsules via F127 micelles based soft-template method in a mild aqueous environment at room temperature . The encapsulation of QDs shows a F127: QDs mass ratio dependent behavior, which impact much on the morphology and optical properties of composite nanocapsules . These as prepared composite nanocapsules also exhibit good photoluminescence stability under the temperature ranges from 19 °C to 49 °C. In addition, the aqueous solubility of PTX (0.1 μg/mL) can be efficiently enhanced about 630 times to 62.99 μg/mL, and the loaded PTX could be released during 12 h sustainably. These tunable fluorescence, enhanced drug loading efficiency and sustained release behavior manifest that the hybrid nanocapsule is a promising theranostic nanoplatform for future combined fluorescence imaging and chemotherapy.
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高影响因子
RSC Advances
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2016
·Vol. 6
·期 74
·70452-70459
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IF 3.289
Makkawi Osman,Yanmin Huang,Wei Feng,Guangbo Liu,Yunfeng Qiu,PingAn Hu
Phase engineering of two-dimensional (2D) materials offers unique opportunities for acquiring novel opto-electronic properties and allows for the searching of outstanding candidates for applications in opto-electronic detectors, sensors, catalysis, or phase-change memory devices. Here, we report the phase-transformation from β-InSe to γ-In2Se3, exploiting the thermal annealing route to trigger the process starting at 200 °C that expands the family of phase-change materials. The presence of γ-In2Se3 is solidly confirmed by the characteristic peaks in X-ray diffraction (XRD) and energy dispersive X-ray (EDX), and is quite stable at ambient condition, thus facilitating substantial application in phase-change memory devices. A Raman shift in the A′1 mode from 225 cm−1 to 230 cm−1 further illustrates the phase transformation. Besides the photoluminescence (PL) peak of β-InSe, the ∼2 eV PL peak, ascribed to γ-In2Se3, is observed in the annealed nanosheet. The increased PL band gap of β-InSe as a function of annealing temperature during phase transformation was possibly affected by the suppressed interlayer coupling, as well as the planar quantum confinement of photo-excited carriers by the external surfaces of the sheets. The photodetector performance with respect to photocurrent, mobility, detectivity, responsivity, and external quantum efficiency was subsequently evaluated after thermal annealing, showing deteriorated optical performance. The present work proved that thermal annealing could induce the successful phase transformation, and adjusted the opto-electronic properties in some extent, providing useful information for processing 2D materials based nano-devices.
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Journal of Materials Chemistry B
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2016
·Vol. 4
·期 29
·5059-5067
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IF 4.872
Chao Wei,Yan Zhang,Heng Xu,Ying Xu,Yue Xu,Meidong Lang
Well-defined diselenide-centered biodegradable tri-block copolymers methoxyl poly(ethylene glycol)-b-poly(ε-caprolactone)-b-methoxyl poly(ethylene glycol) (mPEG–PCL–Se)2 were precisely synthesized by the combination of ring opening polymerization using di(1-hydroxyethylene) diselenide as a new initiator and a facile coupling reaction. The amphiphilic block copolymers enabled the formation of self-assembled micelles which revealed an excellent reductive response to glutathione (GSH) due to the unique reduction-responsive cleavage of the diselenide bond. Such GSH response ensured an enhanced release of anticancer drugs (DOX) from the micelles in simulative tumor microenvironments; moreover, the drug release could be changed to some extent through fine-tuning the chemical composition of the copolymers. Flow cytometry and confocal laser scanning microscopy (CLSM) measurements confirmed that the DOX-loaded micelles could be efficiently taken up by oral squamous carcinoma (HN30) cells and DOX was released into the nuclei of cancer cells following 4 h of incubation. The cell viability assays showed the diselenide-containing polymers were nontoxic up to a tested concentration (400 μg mL−1), while the DOX-loaded micelles exhibited an evident inhibition toward HN30 cells. Therefore, the reduction-labile biodegradable (mPEG–PCL–Se)2 may offer an alternative platform for tumor-targeting therapy.
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Materials Science & Engineering C-Materials for Biological Applications
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2016
·
IF 3.42
Na An,Huiming Lin,Chunyu Yang,Ting Zhang,Ruihan Tong,Yuhua Chen,Fengyu Qu
The targeting drug release is significant to the anticancer treatment. In this context, the redox-responsive drug delivery has attracted most attention owing to the intracellular reductive environment, such as the high concentration of glutathione reductase in many cancer cells. Herein, a glutathione sensitive drug delivery nanoplatform was constructed by using core-shell mesoporous silica nanocomposite (Fe 3 O 4 @mSiO 2 ) as carrier. By a simple silane coupling reaction, the glutathione cleavable diselenide linker has been prepared and grafted on to Fe 3 O 4 @mSiO 2 to insure the encapsulation of anticancer drug doxorubicin. The detail release kinetics studies reveal the glutathione triggered drug release, which could be further adjusted by varying the amount of diselenide linker. To improve the tumor-targeting, folic acid was grafted. The cellular uptake and drug release investigation was carried out using HeLa (cervical cancer cell line) as the model cancer cell and L02 and HUVEC (human hepatic cell line and human umbilical vein endothelial cells, non-cancerous cell lines) as control, indicating the enhanced cytotoxicity toward HeLa cells that benefits from the fast endocytosis and enhanced cellular drug release owing to their overexpressing folic acid receptors and high concentration of glutathione. Associating with the magnetic targeting, these novel nanomaterials are expected to be promising in the potential application of tumor-targeting therapy.
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International Journal of Green Energy
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2016
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IF 1.601
Zhimin Liu,Weiling Luan,Binxia Yuan,Lin Jin,Shan-Tung Tu
CdS and CdSe quantum-dots-sensitized solar cells (QDSSC) consisted of highly ordered, vertically oriented TiO2 nanotubes were reported. TiO2 nanotubes served both as a large-area support for quantum dots and high-efficiency electron-transporting medium. Anodization method was investigated to fabricate nanotubes directly growing on Ti foil with various anodization time. Under illumination of one sun, the as-obtained QDSSC provided a power conversion efficiency of 1.61%.
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Journal of Materials Chemistry B
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2017
·Vol. 5
·期 41
·8152-8160
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IF 4.543
Jie Zhang,Jie Wang,Tong Yan,Yanan Peng,Dajun Xu,Dawei Deng
Quantum dots (QDs) exhibit many unique optical properties, and show great promise as fluorescent markers in molecular, cellular and in vivo imaging. In this thematic issue, a major concern is their cytotoxicity. Among various Cd-free alternatives, InP-based QDs without highly toxic heavy metal elements have received the most attention. This article first focuses on the synthetic control of oil-soluble InP/ZnSe/ZnS QDs, exhibiting strong dual emissions, namely, visible excitonic emission and near-infrared (NIR) surface defect emission. Next, the organic-to-aqueous phase transfer of the dual emissive QDs was explored systematically. It was found that the dual emissions are relatively stable against the water transfer strategies used here; among them, aqueous dual emissive QDs obtained by wrapping oil-soluble QDs with a poly(acrylic acid)-octylamine (PAA-based) amphiphilic polymer (or modified with the cRGD peptide) exhibit enhanced NIR emission. Finally, using in vitro cell and in vivo small animal optical imaging techniques, the bioactivities of the cRGD-modified amphiphilic polymer-wrapped QDs were also investigated. The results confirm that single-wavelength excitation with strong dual emissions ranging from 550 to >1000 nm will endow the InP-based QDs with the capability for biomedical optical imaging across different spatial scales, as a promising alternative for Cd- and Pb-based QDs.
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ELECTROCHIMICA ACTA
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2017
·
IF 4.798
Baoshan He
A novel 3D heterostructure of carbon aerogel nanospheres embedded in ultrathin MoSe 2 nanoslices is synthesized by a simple method. The morphologies and structure of obtained sample are thorough characterized. Benefiting from the peculiar cross-connected nanostructure , the MoSe 2 nanoslices-carbon aerogel nanospheres hybrids exhibit high specific capacity of 775.3 C g −1 and good cycling stability (keeping 98% of initial specific capacity) after 1500 cycles at 1 A g −1 in 6 mol L −1 KOH, demonstrating hierarchical MoSe 2 nanosheets-carbon aerogel nanospheres hybrids are the high-performance supercapacitor electrode material . Furthermore, the as-prepared materials show an enhanced performance toward the electrochemical sensing of endocrine disruptors 17β-estradiol with a linear range of 0.005–5 nmol L −1 and a detection limit as low as 2.0 × 10 −13 mol L −1 (signal to noise of 3). The encouraging results herein ensure the merits of cross-connected nanostructure. Furthermore, it is beyond all doubt that this work provides a promising preparation strategy to develop transition metal selenides based nano-architecture for energy storage and electrochemical sensing.
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ACS Applied Materials & Interfaces
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2017
·
IF 7.504
Yafang Qi,Qingwen Tian,Yuena Meng,Dongxing Kou,Zhengji Zhou,Wenhui Zhou,Sixin Wu
The partial substitution of Cu+ with Ag+ into the host lattice of Cu2ZnSn(S,Se)4 thin films can reduce the open-circuit voltage deficit (Voc,deficit) of Cu2ZnSn(S,Se)4 (CZTSSe) solar cells. In this paper, elemental Cu, Ag, Zn, Sn, S, and Se powders were dissolved in solvent mixture of 1,2-ethanedithiol (edtH2) and 1,2-ethylenediamine (en) and used for the formation of (Cu1–xAgx)2ZnSn(S,Se)4 (CAZTSSe) thin films with different Ag/(Ag + Cu) ratios. The key feature of this approach is that the impurity atoms can be absolutely excluded. Further results indicate that the variations of grain size, band gap, and depletion width of the CAZTSSe layer are generally determined by Ag substitution content. Benefiting from the Voc enhancement (∼50 mV), the power conversion efficiency is successfully increased from 7.39% (x = 0) to 10.36% (x = 3%), which is the highest efficiency of Ag substituted devices so far.
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RSC Advances
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2017
·Vol. 7
·期 50
·31173-31179
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IF 3.108
Chao Pang,Ruiqiang Yang,Amit Singh,Hanjiao Chen,Michael K. Bowman,Ningzhong Bao,Liming Shen,Arunava Gupta
Anisotropic-shaped CuCr2Se4 nanocrystals have been synthesized by thermal decomposition and reaction of novel mixed metal–oleate complexes with selenium in a high-boiling point organic solvent, trioctylamine (TOA). The synthesized CuCr2Se4 nanocrystals exhibit close to triangular and hexagonal morphology, with an average size of 20 nm. X-ray diffraction patterns and XPS spectral analysis confirm the formation of the pure spinel phase without any impurities. A possible reaction mechanism is suggested and formation pathways for the triangular and hexagonal shaped CuCr2Se4 nanocrystals are proposed. Magnetic studies indicate that the anisotropic-shaped CuCr2Se4 nanocrystals are superparamagnetic near room temperature but exhibit ferromagnetic behavior at lower temperatures, with magnetization values of 31 and 43 emu g−1 at 300 and 5 K, respectively.
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Analytical Methods
·
2016
·Vol. 8
·期 26
·5234-5241
·
IF 1.915
Liu Yang,Yanfu Li
A new electrochemical biosensor based on the hybridization chain reaction and layered molybdenum selenide (MoSe2) stacked nanorod for dual-signal amplification is developed for the highly sensitive detection of the DNA sequences of Human Immunodeficiency Virus type 1 (HIV-1). The MoSe2 nanorod was prepared using a facile hydrothermal method. The glassy carbon electrode was first modified with MoSe2 nanorods and then Au nanoparticles (AuNPs) were electrodeposited on the electrode. The DNA probe was then immobilized on the electrode by an Au–S bond. As the initiator strands, auxiliary DNA can propagate a chain reaction of hybridization events between the two hairpin probes (Aux 1, Aux 2), and long nicked DNA polymers can be formed on the modified electrode. The biotin-labeled dsDNA polymers can then introduce numerous avidin-labeled horseradish peroxidases on the electrode, resulting in a significantly amplified electrochemical signal through the electrocatalysis of horseradish peroxidase. The target DNA is detected on the basis of the enzymatic oxidization of Fe2+ by H2O2. The electrochemical signals have a good linear relationship with the logarithm of target DNA concentration in the range from 10 fM to 0.1 pM, reaching a detection limit of the target DNA as low as 4.0 fM. This method shows good specificity for target DNA detection with the capability to discriminate single-base-pair mismatched DNA mutations. Moreover, the developed strategy was applied successfully in a real sample, which demonstrated the potential applications in clinical diagnostics.
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RSC Advances
·
2016
·Vol. 6
·期 53
·47486-47490
·
IF 3.289
Chenhao Zhao,Libin Xu,Zhibiao Hu,Sheng'en Qiu,Kaiyu Liu
Porous carbon with a unique 3D structure has been prepared by the immediate carbonization of potassium tartrate. At an optimal carbonization temperature of 700 °C, the carbon mainly composed of micro- and small meso-porous structure has a Brunauer–Emmett–Teller (BET) specific surface area of 816.2 m2 g−1, and the element Se with an amorphous structure is uniformly encapsulated into the porous structure of carbon. The weight ratio of Se in the composite can reach ∼50%. As the Li–Se battery cathode, the composite shows a (2nd) reversible discharge capacity of 550.5 mA h g−1 with an initial coulombic efficiency of 68.2% at 0.24C, and a discharge capacity of 485.3 mA h g−1 can be retained after 80 cycles. Even at a high current density of 1.2C, the cell also delivers a stable discharge capacity of about 452.3 mA h g−1. The good electrochemical performances of the as-prepared composite may be attributed to high specific surface area and small porous size.
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JOURNAL OF ALLOYS AND COMPOUNDS
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2017
·
IF 3.133
Chao Cui,Gang Zhou,Weifeng Wei,Libao Chen,Chengchao Li,Jianling Yue
In this work, a facile strategy for embedding graphene (GR) nanosheets into carbon-coated MoSe 2 (MoSe 2 @C@GR) hybrid nanofibers has been developed by a simple electrospinning route. One dimensional nanofibers have excellent structural stability resulting from strong tolerance to stress change. The highly conductive graphene nanosheets play an excellent coating effect on MoSe 2 to inhibit the growth of MoSe 2 nanosheets on the nanofiber surface and enhance the conductivity of hybrid nanofibers, which substantially improves the rate performance and cycle stability of carbon-coated MoSe 2 (MoSe 2 @C) nanofibers. In particular, the MoSe 2 @C@GR electrode delivers a high discharge capacity of 366.9 mAh g −1 after 200 cycles at 0.2 A g −1 , meanwhile exhibits superior rate performance. The analysis of Nyquist plots reveals that the addition of graphene nanosheets can greatly strengthen the kinetics of electrode reaction and the electrochemical activity.
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