INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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2022
·Vol. 23
·期 15
·8743
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IF 6.208
Baojuan Deng,Yadan Luo,Meijiao Peng,Tao Li,Jianwei Su,Yang Wang,Xuelian Xia,Chengqi Feng,Shuangquan Yao
As a green and efficient component separation technology, organic acid pretreatment has been widely studied in biomass refining. In particular, the efficient separation of lignin byp-toluenesulfonic acid (p-TsOH) pretreatment has been achieved. In this study, the mechanism of the atmospheric separation of bagasse lignin withp-TsOH was investigated. The separation kinetics of lignin was analyzed. A non-simple linear relationship was found between the separation yield of lignin and the concentration ofp-TsOH, the temperature and the stirring speed. The shrinking nucleus model for the separation of lignin was established based on the introduction of mass transfer and diffusion factors. A general model of the total delignification rate was obtained. The results showed that the process of lignin separation occurred into two phases, i.e., a fast stage and a slow stage. The results provide a theoretical basis for the efficient separation of lignin byp-TsOH pretreatment.Keywords:p-toluenesulfonic;lignin;mechanism;kinetics;shrinking nucleus model
研究领域:
生物质能
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化学工程
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DOI
PubMed
高影响因子
ACS Applied Polymer Materials
·
2025
·
IF 4.7
Yufu Gao,Shaohua Wu,Chuncheng Li,Yaonan Xiao,Jiajian Liu,Mingxuan Du
Poly(p-phenylene benzobisoxazole) (PBO) fibers exhibit poor hydrophilicity, which necessitates the use of highly corrosive acids as solvents during papermaking. This severely restricts the research and development of PBO paper. To address this limitation, the present study proposes an innovative and environmentally benign strategy for fabricating high-performance PBO paper using water as the solvent. In this strategy, nanofibers with excellent hydrophilicity are employed as stabilizers, which adsorb onto the surface of PBO fibers through π–π stacking interactions, thereby significantly improving the aqueous dispersibility of PBO fibers. Furthermore, the interlacing and interconnection of nanofibers effectively enhance the interfacial interactions between PBO fibers, leading to a substantial improvement in the overall performance of PBO paper. Compared with the pristine PBO paper, the modified one exhibits a 23-fold increase in tensile strength and a 1.6-fold increase in electrical breakdown strength, while retaining its inherent flexibility, thermal resistance, dielectric properties, and processability. This work holds great significance for promoting the large-scale production of PBO paper and expanding its applications in fields requiring high thermal resistance, wave transmission capability, and electrical insulation performance.
研究领域:
材料科学
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高分子工程
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纳米复合材料
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造纸技术
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电气绝缘材料
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产品关联
DOI
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2019
·
IF 3.218
Huang Chen,Peng Sun,Meijia Qiu,Min Jiang,Jie Zhao,Dongxue Han,Li Niu,Guofeng Cui
In response to the challenges posed by diabetes, portable glucose sensors with enzyme-free catalytic materials have received great attention in recent years. Herein, a facile strategy for fabricating inexpensive and efficient electrochemical sensors is proposed. Flexible copper clad laminate (FCCL) can be firstly decorated with nanoporous copper (NP Cu) through electrodepositing Cu-Sn alloy and dealloying the Sn element. Then Co-P is further electrodeposited onto the NP Cu/FCCL and the final Co-P/NP Cu/FCCL composite electrode exhibits high catalytic activity for glucose. The great performance of the Co-P/NP Cu/FCCL mainly derives from the enlarged surface area of the NP Cu and the high electrocatalytic activity of Co-P. This electrode exhibits a high sensitivity of 1818 μA cm −2 mM −1 , low limit of detection of 378 nM (S/N = 3), fast response time of 4 s, a wide linear dynamic range of 0.5 μM to 10.0 mM, good anti-interference performance, excellent repeatability and considerable stability for glucose detection. The well-designed structure for catalyzing glucose in high efficiency enable the Co-P/NP Cu/FCCL a potential candidate for future flexible electrochemical sensors.
研究领域:
材料科学
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电化学
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生物传感器
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纳米技术
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DOI
高影响因子
RSC Advances
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2014
·Vol. 4
·期 93
·51558-51568
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IF 3.708
Fangzhuan Liu,Lingyu Wang,Qinjian Yin,Bo Jiang
In the present work, the conductive nanocomposite of poly(p-phenylenediamine)(PpPD)/exfoliated graphene nanoplatelets (GNPs) are synthesized via in situ polymerization under acidic conditions by doping different percentages of GNPs. The interactions between PpPD and GNPs are investigated by utilizing infrared spectra (FTIR), transmission electron microscopy (TEM), scanning electron microscopy (SEM), UV-visible, Raman spectra, thermogravimetric analysis (TGA) and X-ray diffraction (XRD). It is observed that the reticular strip-like PpPD are adsorbed on the surface of the GNPs, which can be fabricated by loading different percentages of GNPs. Thermoelectric properties (electrical conductivity, Seebeck coefficient and thermal conductivity) of pellets obtained by cold pressing are determined at room temperature. Compared with pure PpPD, it is observed that the presence of GNPs is an essential component for the improvement of the thermoelectric properties of the resulting nanocomposite, which reach the maximum of 193.245 S m−1 and 58 μV K−1, while the thermal conductivity of the composites relatively maintains low values even with high GNPs content, resulting in the increase in the dimensionless figure of merit (ZT). The highest ZT value of 3.63 × 10−4 has been obtained for the composite containing 50 wt% GNPs at 55 °C.
研究领域:
材料科学
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物理化学
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DOI
高影响因子
ACS Applied Materials & Interfaces
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2021
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IF 9.229
Yihan Wang,Siqi Wu,Qinjian Yin,Kai Du,Qiang Yin,Bo Jiang,Site Mo
Mussel-inspired polydopamine (PDA) can serve as building blocks and interfaces in designing functional materials. Here, the use of PDA as an interlayer between polyaniline (PANi) and multidimensional carbon materials, such as graphene quantum dots (GQD), multiwalled carbon nanotubes (MWCNT), and graphene nanosheets (GNS), to improve the thermoelectric performance of p-type polymer-based materials has been reported. The introduction of PDA promotes the carrier mobility of GQD/PDA/PANi, CNT/PDA/PANi, and GNS/PDA/PANi ternary composites due to the superior adhesive property of PDA. An optimal conductivity of 4.98 × 104 S m–1 and a power factor of 92.17 μW m–1 K–2 at 363 K are achieved in GNS/PDA/PANi, which are much higher than the values of GNS/PDA and GNS/PANi. More surprisingly, despite the fact that GQD/PDA, CNT/PDA, and GNS/PDA binary composites show p-type properties, the pyrolysis treatment of GQD/PDA, CNT/PDA, and GNS/PDA at 800 °C results in a gain in both the electrical conductivity and negative Seebeck coefficient of c-GQD/PDA, c-CNT/PDA, and c-GNS/PDA. The c-CNT/PDA composites possess the highest Seebeck value of −30.2 μV K–1 and a maximum power factor value of 35.57 μW m–1 K–2. Finally, a flexible thermoelectric generator with 24 thermoelectric units composed of GNS/PDA/PANi and c-CNT/PDA is demonstrated, which gives an output voltage of 52.8 mV at a temperature difference of 60 °C.
研究领域:
材料科学
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有机化学
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能源材料
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DOI
PubMed
高影响因子
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY
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2019
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IF 2.697
Siwen Kuang,Qijun Le,Jiabao Hu,Yajun Wang,Na Yu,Xiaohuan Cao,Man Zhang,Yibo Sun,Weiwei Gu,Yang Yang,Youyi Zhang,Yaya Li,Hanwei Liu,Xiaojun Yan
p-Nitrophenol (PNP) is one type of environmental pollutant, which is difficult to degrade and soluble in water. To investigate the effects of PNP on economically important marine fish species, we subjected Larimichthys crocea juvenile to five different concentrations of PNP for 96 h, and the semi-lethal concentration (LC50) was 6.218 mg/L. Then we collected the liver, kidney, and gill tissues to determine enzyme activity and gene expression levels , and analyzed histological changes. In histological analysis, the gills showed curling of lamella, epithelial lifting and hyperplasia ; the parenchymal structure of hepatocytes was significantly damaged, with severe vacuolation and loss of original structure. The renal cells were damaged too, with congestion and renal tubular necrosis . Catalase and superoxide dismutase both showed an up- and down-tendency with the rise of concentration in the three tissues, and GSH-px had similar trend in the kidney, which decreased at 8 mg/L in the liver but showed no significant differences in the gills. Malondialdehyde of three tissues was increased with an increase in PNP concentration. The expression of four detoxification ( cyp450 , gst , gpx, hsp70 ) and one immune-related ( mhc II ) genes was induced at low PNP concentrations but inhibited at high PNP concentrations in the kidney. In liver, cyp450, hsp70 and mhc II showed similar trend but gst and gpx didn't increase at low PNP concentrations. Our results indicate that the fish possesses the ability to detoxify PNP; however, at high concentrations, PNP still causes serious damage to them. Our data not only help in understanding the ability of L. crocea to detoxify PNP but also should serve as a basis for the study of toxic effects of nitrobenzenes on marine fish.
研究领域:
海洋生物学
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环境毒理学
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分子生物学
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DOI
PubMed
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
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2017
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IF 2.843
Xinqiang Feng,Chun Shen,Chenchen Tian,Tianwei Tan
Aimed at highly selective production of p-xylene (PX) from biomass-derived 2,5-dimethylfuran with a high carbon balance, SiO2 supported with sulfonic acid was especially designed and prepared. As one kind of the most widely used Brønsted acid, sulfonic acid groups were chosen as the active sites of probes. The density of sulfonic acid groups in the whole composite was highly adjustable, ranging from 4.7–540.6 μmol/g. The catalytic activity was strongly related to the acid concentration and location: the one with active sites mainly on the exterior surface exhibited much better catalytic activity by facile mass transfer through mesopores. The suitable acid species and structures of the as-prepared catalyst contributed to the improved activity: a selectivity of 89% and a carbon balance of 95% were achieved at 523 K. Overall, this new reusable catalyst provided an alternative for highly efficient production of biobased PX.
研究领域:
催化化学
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生物化工
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能源化学
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DOI
高影响因子
Molecular Catalysis
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2022
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IF 5.089
Dongting Wu,Ye Lv,Wei Li,Yan Fu,Jinli Zhang
It is highly challenging to develop efficient catalysts for selective oxidation of p-chlorotoluene (PCT) into p-chlorobenzaldehyde (PCB) as PCB easily undergoes over-oxidation. Herein, a new electrochemical strategy was developed for selective oxidation of PCT with high selectivity toward PCB. A self-standing molybdenum phosphide (MoP) anode was directly synthesized on carbon cloth with the assistance of polyvinyl pyrrolidone. The as-synthesized MoP anode with 3D network structure, exhibits the selectivity of 91.4% toward PCB at the conversion of 75.6% in acetonitrile solution containing 0.1 M Bu 4 NClO 4 . During electrochemical oxidation, molecular oxygen-induced transformation of MoP into MoO 2 initiates the activation of PCT into ClC 6 H 5 CH 2 + . The ClC 6 H 5 CH 2 + reacts with molecular O 2 over electrode surface, producing the product of PCB. This work offers a promising strategy to achieve selective oxidation of C H bond based on electrochemical environment.
研究领域:
电化学
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材料科学
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催化
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环境化学
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DOI
高影响因子
JOURNAL OF POWER SOURCES
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2026
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IF 8.4
Ling Sheng,Hang Wang,Shaoyang Wu,Fan Wu,Xin Ye,Kang Liang,Jianbin Li,Peng Wei,Yurong Ren
Pitch serves as an economical substance characterized by a high carbon output, rendering it appropriate for employment as negative electrode components in Na-ion batteries, thereby facilitating enhanced value-added utilization. However, through direct thermal decomposition of pitch, the resulting carbon materials characterized by high graphitization, reduced interlayer spacing, and challenges in sodium ion deintercalation, ultimately leading to limited electrochemical performance. To expand the carbon interlayer spacing, this study adopted the phosphorus doping strategy, using NaH 2 PO 2 as the phosphorus source, which interacts with the aromatic molecules in pitch to form P-C bonds. The introduction of P-C bonds effectively suppressed graphite microcrystal development during high-temperature carbonization, resulting in decreased graphitization levels and expanded interlayer distances in the carbon matrix. Besides, P-C bonds demonstrate dual functionality by improving sodium ion adsorption while simultaneously reacting with alkali metal Na + to form Na x PC y , which directly participated in sodium storage. Consequently, the soft carbon material that has been doped with phosphorus showcases enhances sodium storage capabilities when compared to traditional soft carbon material obtained through direct pyrolysis, achieving a discharge capacity of 138.56 mAh g −1 when tested over 3500 cycles at 1 A g −1 . Therefore, this research demonstrates a simple and effective method for utilizing pitch in the sodium-ion batteries.
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高影响因子
JOURNAL OF CATALYSIS
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2026
·
IF 6
De Xia,Hao Wang,Ben Li,Bing Lu,Yong Wang,Shanjun Mao
This study presents a novel Rh 7 Ni 1 P 4 /SiO 2 catalyst that significantly improves the hydroformylation of olefins, achieving a turnover frequency of 3433h −1 . By incorporating nickel (Ni) and phosphorus (P) into rhodium (Rh), the electronic structure of Rh was effectively modified, enhancing olefin adsorption and reducing CO binding energy. This dual modulation boosts catalytic performance by shifting the rate-determining step from CO insertion to acyl hydrogenation, thereby accelerating the reaction rate. Experimental results, supported by density functional theory (DFT) calculations, reveal that the Rh 7 Ni 1 P 4 /SiO 2 catalyst reduces Rh-CO interactions, minimizes rhodium leaching, and exhibits excellent stability over multiple cycles. This research advances the design of robust and efficient catalysts for industrial hydroformylation processes.
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产品关联
DOI
高影响因子
Journal of Advanced Research
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2026
·
IF 13
Yimei Zheng,Boyu Chen,Xuanxiang Huang,Chao Ai,Hui Teng,Lei Chen
Introduction The poor bioavailability of luteolin, a potent flavonoid with antioxidant and anti-inflammatory properties, hinders its therapeutic potential. The primary barriers to its absorption are its low solubility and active efflux by P-glycoprotein (P-gp) in the gastrointestinal tract. Objectives To overcome these absorption barriers, we developed a functional self-microemulsifying drug delivery system (SME) incorporating D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS), aiming to simultaneously enhance solubility, inhibit P-gp efflux, and improve the oral bioavailability and therapeutic efficacy of luteolin. Methods A TPGS-based luteolin-SME was prepared via self-assembly and characterized for particle size, stability, release profile, and antioxidant capacity. Cellular absorption mechanisms, permeability, and P-gp inhibition were evaluated using Caco-2 monolayers and molecular docking. Pharmacokinetics and biodistribution were assessed in rats, and therapeutic efficacy was examined in a lipopolysaccharide-induced inflammation model. Results The optimized luteolin-SME formed uniform nanodroplets (<50 nm) with high stability and achieved a 4.3-fold higher cumulative release compared to free luteolin. In Caco-2 cells, the formulation significantly enhanced cellular uptake and permeability, primarily via clathrin- and caveolae-mediated endocytosis, and effectively inhibited P-gp efflux. Pharmacokinetically, luteolin-SME provided a 29-fold increase in relative bioavailability (AUC 247.729 vs. 8.628 mg/L·h) and a 16-fold higher Cmax (27.546 mg/L) over free luteolin. In the lipopolysaccharide-induced inflammation model, luteolin-SME markedly attenuated oxidative stress, reducing the TNF-α, IL-6, and IL-1β levels by approximately 37%, 26%, and 39%, respectively. Conclusion The TPGS-functionalized SME effectively overcame the major absorption barriers of luteolin by integrating nanocarrier-enhanced solubilization with active P-gp inhibition. This dual strategy resulted in unprecedented oral bioavailability enhancement and potent efficacy. Our study establishes a robust and clinically promising delivery platform for luteolin and other poorly soluble, efflux-limited bioactive compounds, offering a practical approach to enhance oral therapy for inflammation-related diseases.
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产品关联
DOI
PubMed
高影响因子
Scientific Reports
·
2020
·Vol. 10
·期 1
·1-12
·
IF 3.998
Bo Caiying,Shi Zhongyu,Hu Lihong,Pan Zheng,Hu Yun,Yang Xiaohui,Jia Puyou,Ren Xiaoli,Zhang Meng,Zhou Yonghong
A novel eco-friendly halogen-free cardanol-based flame retardant with P, Si, and N on the chain backbone (PSNCFR) was synthesized and incorporated into phenolic foams (PFs). PSNCFR was comprehensively investigated via Fourier transform infrared spectroscopy and nuclear magnetic resonance. PSNCFR endowed PFs with flame retardancy, contributed to generating a composite char defense against flames, and efficiently prevented smoking from PFs. PSNCFR introduction improved the flexural strength of the PFs to approximately 155% of that of pristine PF. PSNCFR-modified PFs displayed a high limiting oxygen index value of 41.9%. The results of cone calorimeter show that the mean heat release rate, mean effective heat of combustion, and total heat release of the PSNCFR-modified PFs reduced by 26.92%, 35.71%, and 31.25%, respectively. In particular, the total smoke production of the PSNCFR-modified PFs decreased by 64.55%, indicating excellent smoke inhibition. As for the mechanism, the condensation and gas phases during pyrolysis were responsible for the synergistic flame retardancy in the modified PFs. The findings demonstrate that PSNCFR can be used in PF preparation to overcome their drawbacks of internal brittleness and flammability.
研究领域:
材料科学
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化学工程
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DOI
高影响因子
危险品化学品经营许可证（带存储）