JOURNAL OF SEPARATION SCIENCE
·
2025
·Vol. 48
·期 1
·e70082
·
IF 2.8
Bincheng Gong,Lingqi Shen,Yu Wang,Zuguang Li,Guohua Zhu
Tea saponin has garnered tremendous interest for its potential use in surfactant and drug synthesis. This research was designed to develop a technique based on pH-responsive switchable deep eutectic solvents (SDESs) for extracting tea saponins from Camellia oleifera seed meal. SDES synthesized from hexanoic acid and triethanolamine (1:1 molar ratio) offered the optimum extractive performance and the optimal conditions were obtained through single-factor experiments: 30 wt% water content in SDES, solid-liquid ratio of 1:30 g/mL, 60°C extraction temperature, 30 min extraction time, and acid volume of 1500 µL. The extraction yield was 162.14 mg/g after optimization, which increased by 15.65% and 9.47% compared to water and ethanol extraction methods, respectively. After pH adjustment, 98.95% of the tea saponins were recovered in the bottom phase. After precipitation and freeze-drying procedures, the purity of the tea saponin solid was 62.9%.
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LANGMUIR
·
2024
·
IF 3.7
Yutuo Zheng,Songyao Zhang,Xiaoyang Zhao,Xinrui Miao,Wenli Deng
The self-assembly behaviors of aromatic carboxylic acids are commonly investigated at the liquid/solid interfaces because of their rigid skeletons and both hydrogen-bond donors and receptors. However, self-assemblies of aromatic carboxylic acids with low symmetry and interactions between carboxylic acid and pyridine derivatives are worth exploring. In this work, the self-assembled structural transitions of a kind of low-symmetric aromatic carboxylic acid (H4QDA) are regulated by the coadsorption of two pyridine derivatives (DPE and T4PT) with different symmetry, which are investigated by scanning tunneling microscopy under ambient conditions. For the H4QDA/DPE system, the grid structure appears. For the H4QDA/T4PT system, the coassembled morphologies display an obvious concentration dependence. With the increase of solution concentration of T4PT, three coassembled patterns (network structure, chiral linear structure, and brick-like structure) are observed. Corresponding structural models suggest that the O–H···N hydrogen bonds have great contributions to stabilizing these coassembled structures. Our studies will help to explore the complexity, diversity, and functionality of multiple component systems and are conducive to further understanding the underlying mechanisms in the assembly process.
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TRIBOLOGY INTERNATIONAL
·
2024
·
IF 6.1
Yiquan Wang,Yuxiang Liang,Yiya Li,Wenqi Rui,Jingjian He,Mengya Zhao
The performance requirements for extreme pressure and anti-wear properties, as well as oxidative stability, are increasingly stringent for MIL-PRF-23699G Enhanced Ester (EE) for aviation turbine engine lubricants. An oligomerization reaction of pentaerythritol through direct esterification using pentaerythritol and dibasic acid catalyzed by tetrabutyl titanate in xylene solvent, was employed to achieve the low-polymerization reaction of dibasic acid and pentaerythritol. A two-step synthesis process yielded a mixed ester comprising dibasic acid pentaerythritol complex ester and pentaerythritol tetrapentanoate. These mixed esters demonstrate excellent viscosity-temperature performance and good oxidative stability, significantly enhancing the extreme load-carrying properties and anti-wear properties of pentaerythritol tetrapentanoate. Molecular dynamics (MD) calculations indicate that complex esters possess higher adsorption energy and molecular interaction energy, enhancing the possibility of ester molecules adsorbing on metal surfaces and producing stronger oil film that can withstand large loads. The novel 5 mm 2 /s pentaerythritol ester containing diacid pentaerythritol complex esters exhibits improved viscosity-temperature performance, high-temperature oxidation resistance, and better tribological properties. Therefore, the novel pentaerythritol esters show potential for application in 5 mm 2 /s EE aircraft engine lubricants.
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Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Le Gou,Zhentao Ping,Liyi Dai,Yuanyuan Wang
Organic acids are commonly used additives in the hydrothermal carbonization (HTC) of sewage sludge (SS). Previous studies have demonstrated that organic acids can effectively increase the carbon content of hydrochar, reduce its nitrogen content, and improve its combustion performance. Due to significant differences in molecular structure and chemical reactivity among organic acids with varying carbon chain lengths, they may exert distinct influences on hydrochar yield, carbon content, and combustion behavior. However, there remains a lack of systematic research on the effects of organic acids with varying carbon chain lengths during the HTC process. In this study, an orthogonal experimental design was employed to investigate the influence of C1 to C9 organic acids on the carbon content of hydrochar under various temperatures (170–230 °C) and concentrations (0.1–0.5 mol/L). The results showed that as the carbon chain length increased, organic acids were more likely to incorporate into the hydrochar structure through chemical reactions, resulting in a gradual increase in both carbon content and calorific value. Furthermore, the addition of long-chain organic acids led to a reduction in nitrogen content and enhancement of the combustion characteristics of the hydrochar. Meanwhile, long-chain organic acids were also beneficial for the recovery of nutrients from the aqueous phase. These findings provide a systematic reference for improving hydrochar quality and promoting aqueous phase resource recovery in the HTC of SS using organic acids.
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FOOD CHEMISTRY
·
2025
·
IF 9.8
Lingqi Shen,Yuan Yan,Xiaoyan Jiang,Xuerong Yang,Zhihui Zhang,Zuguang Li
As new green solvents, the low volatility of deep eutectic solvents (DESs) limits their development in natural product extraction. In this work, a series of novel lower critical solution temperature (LCST) type temperature-responsive DESs (TRDESs) were prepared and applied to the extraction of carotenoids from tomato. The highest yields (408.85 ± 4.97 μg/g of lycopene, 68.78 ± 2.00 μg/g of β-carotene) were obtained under the following conditions: extractant DES-16 (methyl 1-benzylpiperidine-4-carboxylate: valeric acid: heptanoic acid = 2:1:1), solid-liquid ratio 1:58 g/mL, extraction temperature 68 °C, and extraction time 44 min. Utilizing the temperature response characteristics of TRDESs, the separation of carotenoids and TRDESs was achieved in a mild way. Upon analysis, hydrophilic polysaccharides were simultaneously extracted and retained in water through the recovery experiment. Green Analytical Procedure Index (GAPI) proved the greenness of the method. This work provides new ideas for DESs in the extraction of natural products.
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LANGMUIR
·
2025
·
IF 3.9
Ke-Xin Zhang,Ye Hong,Lu Wang,Ting Chen,Dong Wang
Halogen bonding interactions are crucial in the design of 2D supramolecular assemblies. In this study, we introduce the N-oxide moiety as a halogen-bonding acceptor for the formation of 2D coassemblies. The monomers 4,4’-bipyridine N,N’-dioxide (BPYD) and 1,3,5-trifluoro-2,4,6-triiodobenzene (1,3,5-TFTIB) coassemble into well-ordered, close-packed nanoarchitectures on HOPG surfaces. BPYD forms both halogen and hydrogen bonds with 1,3,5-TFTIB, resulting in pentameric structural units. At high concentrations, these units pack into dense ordered structures. When octanoic or nonanoic acid is used as a solvent, the formation of a 3-component linear structure with the interdigitated solvent molecules between the linear-arranged pentameric units is observed at low concentrations of reactants.
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ULTRASONICS SONOCHEMISTRY
·
2025
·
IF 9.7
Yuhan Fang,Ping Zhang,Shuang Wang,Lulu Li,Zunlai Sheng
This study innovatively employs ultrasound-assisted extraction (UAE) in conjunction with supramolecular solvents (SUPRAS) for the extraction of luteolin from peanut shells, while also investigating the potential mechanism underlying this extraction process. Initially, the formation mechanism of SUPRAS was characterized using Fourier-transform infrared spectroscopy (FTIR). Based on the results of single-factor experiments, the extraction process was optimized using response surface methodology (RSM), resulting in the determination of optimal conditions: an ultrasound temperature of 67 °C, a SUPRAS/equilibrium solution (EqS) volume ratio of 5:1, and a solid-to-liquid ratio of 1:36 g/mL. Under these conditions, the maximum luteolin yield reached 1.645 mg/g. Furthermore, through independent gradient model (IGMH) calculations, molecular orbital theory, interaction energy analysis, and molecular dynamics simulations, it was revealed that the predominant interaction force between the supramolecular solvent and the target compound is hydrogen bonding. Notably, this study also compares the SUPRAS-UAE extraction method with the traditional extraction in terms of efficiency, economic costs, and environmental impact. The results indicate that the SUPRAS-UAE technique demonstrates significant advantages in terms of its green and high-efficiency characteristics. It provides a new sustainable strategy for the efficient recovery of natural active ingredients in chemical engineering and related fields.
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ACS Earth and Space Chemistry
·
2025
·
IF 2.9
Yaru Song,Minglan Xu,Jianlong Li,Narcisse Tsona Tchinda,Kun Li,Lin Du
Atmospheric release of nuclear wastewater results in the introduction of radionuclides into seawater. These radionuclides can be transported back to the atmosphere by interacting with organic matter at the surface of marine aerosol. Organic molecules, such as organic acids (OAs) and alcohols, the primary components of the organic coating on marine aerosol, play a crucial role in this process. However, the discriminated mechanisms of the interactions of these OAs and organic alcohols at the marine aerosol surface urgently need to be explored. This study uses a Langmuir trough to mimic the marine aerosol surface and investigates the interactions of several OAs (formic acid, hexanoic acid, heptanoic acid, octanoic acid, and nonanoic acid) and dodecanol at seawater-relevant ratios. It was found that upon their addition, metal ions (Ba2+, Co2+, Mn2+, Cs+, Sb3+, Sr2+, Rh3+, Ru3+, and La3+) acting as proxies of radionuclides effectively interacted with the carboxyl headgroups of OAs, which was manifested as a significant increase in the carboxylate asymmetric stretch. This asymmetric stretching vibration is significantly increased with the metal ion concentration and enrichment. Furthermore, the apparent surface binding affinity of metal ions with hexanoic acid is significantly higher than that with nonanoic acid, by a factor of ∼1.95. These findings are significant for understanding how metal ion enrichment at the air-sea interface influences the behavior and fate of radionuclides in the marine atmosphere. Additionally, this study provides new insights into the complex interactions between organic compounds and metal ions, offering valuable perspectives and methodologies for advancing research in marine chemistry and environmental science.
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Foods
·
2025
·Vol. 14
·期 21
·3781
·
IF 5.1
Yangyang Sun,Heyun Zhang,Huan Zhang,Jihong Huang,Liping Du,Juan Wang
At present, the classification of nongxiangxing baijiu (NXB) predominantly relies on the subjective expertise of distillers and tasters, in the absence of scientifically standardized criteria. This reliance poses challenges for achieving precise classification. Consequently, there is an urgent need to employ flavoromics technology to identify the key characteristic aroma compounds that distinguish different grades of NXB. This study uses sensory evaluation, an electronic nose, and three-dimensional fluorescence spectroscopy to determine the significant differences in aroma profiles among different grades of NXB. Further, 112 compounds were identified by GC-MS, and quantitative analysis was conducted on 33 major volatile compounds. Using odor activity value (OAV) analysis, it found 21, 23, and 26 key aroma compounds (OAV ≥ 1) in Grade 2 (G2), Grade 1 (G1), and prime-grade (GP), respectively. Aroma recombination successfully simulated the aroma distribution of different grades of NXB, and omission experiments identified 11 key aroma compounds as the foundation for NXB. Additionally, each grade exhibited a unique profile of key compounds. G2 was characterized by the presence of octanoic acid, which imparts sweaty and cheesy aromas. G1 contained benzoic acid ethyl ester, phenethyl acetate, pentanoic acid, 2-methyl-1-propanol, and furfural, contributing to sweet, floral, sweaty/cheesy, alcoholic, and roasted aromas. GP demonstrated higher concentrations of aroma compounds compared to G1 and G2, with distinctive compounds such as decanoic acid ethyl ester, dodecanoic acid ethyl ester, 3-methyl-1-butanol, and 1-hexanol, which are associated with sweaty/cheesy, fruity, and alcoholic aromas. This study elucidated the role of these compounds in determining the flavor profiles of various NXB grades, thereby providing a theoretical foundation for the quality grading of NXB.
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EUROPEAN FOOD RESEARCH AND TECHNOLOGY
·
2025
·
IF 3.2
Li Dan,Wu Xue,Li Yujia,Duan Cuicui,Ma Fumin,Li Xiaolei
To develop a ginseng vinegar in a short production time, the liquid fermentation of 9 days was carried out with the bacteria Acetobacter pasteurianus and Acetobacter ghanensis and the carbon source ethanol. The ginseng vinegar fermented with A. pasteurianus (AAB-hn) exhibited higher total flavonoid and polyphenol contents than ginseng vinegar fermented by A. ghanensis (AAB-jc), which reached 265.51 mg/L and 26.21 mg/L, respectively. 8 organic acids including oxalic acid, tartaric acid, malic acid, lactic acid, acetic acid, citric acid, succinic acid and fumaric acid were quantified by HPLC. Acetic acid was found to be the predominant organic acid in both samples. 108 volatile organic compounds (VOCs) were identified by GC-MS and GC-IMS. 28 differentially metabolites(VIP>1)including esters and acids were screened by OPLS-DA analysis. 10 key-VOCs were further confirmed by GC-O and odor activity values (OAVs ≥ 1). Nonanal, 2-methoxy-4-vinylphenol, and 2(3H)-furanone, dihydro-5-pentyl- were aroma factors unique to the two ginseng vinegars. Linalool and 1-octen-3-ol with floral and mushroom aromas were only detected in the AAB-hn, while α-terpineol and β-damascenone with anise and rose-like aromas were only discovered in the AAB-jc. E-nose and principal component analysis (PCA) can effectively differentiate different samples. AAB-jc had the highest overall score of 82.83 in the sensory evaluation. This study provided key insights into optimizing ginseng vinegar production by exploiting strain-specific metabolic capabilities for the development of functional vinegars with tailored health benefits and sensory profiles. Graphical abstract
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Thoracic Cancer
·
2020
·Vol. 11
·期 6
·1476-1486
·
IF 2.61
Kun Zheng,Runze Chen,Yanxue Sun,Zhenquan Tan,Ye Liu,Xiao Cheng,Junke Leng,Zhaoming Guo,Pengcheng Xu
Background Although photodynamic therapy (PDT) has emerged as a potential alternative to conventional chemotherapy, the low reactive oxygen species (ROS) yield of the photosensitizer such as TiO 2 nanoparticles has limited its application. In addition, it is difficult to achieve effective tumor treatment with a single tumor therapy. Methods We used TiOx nanocomposite (YSA-PEG-TiO X ) instead of TiO 2 as a photosensitizer to solve the problem of insufficient ROS generation in PDT. Benefiting from the desired mesoporous structure of TiOx, Cantharidin (CTD), one of the active components of mylabris, is loaded into TiOx for targeted combination of chemotherapy and PDT. The cellular uptake in human non-small cell lung carcinoma cell line (A549) and human normal breast cell line (MCF 10A) was evaluated by confocal microscopy. in vitro cytotoxicity was evaluated using Cell Counting Kit-8 assay. The ROS was detected via a chemical probe DCFH-DA and the photodynamic treatment effect of YSA-PEG-TiOx was further evaluated by a living-dead staining. The cell apoptosis was detected by the flow cytometry. Results Our findings showed that the modification of YSA peptide improved the cytotoxicity of YSA-PEG-TiO X /CTD to EphA2 overexpressing A549 non-small cell lung cancer (NSCLC) than non-YSA modified counterparts. In addition, TiOx generated adequate ROS under X-ray irradiation to further kill cancer cells. Flow analysis results also proved the superiority of this combined treatment. Conclusions YSA-PEG-TiO X nanoparticles could significantly increase ROS production under X-ray exposure and provide a new drug delivery nanocarrier for CTD in combination with PDT to achieve effective NSCLC treatment.
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MOLECULES
·
2025
·Vol. 30
·期 7
·1599
·
IF 4.6
Yang Li,Ying Wang,Longbo Zhang,Yanru Zhang,Jia Guo,Yanyan Wang,Chenglong Yu,Jun He,Zhenpeng Wang,Juanjuan Han,Qian Li,Tianbin Wu,Qingli Qian,Buxing Han
CO2is a greenhouse gas and a nontoxic, easily available and renewable C1feedstock. H2is a clean and cheap reductant that can be obtained from renewable energy. Olefins are platform chemicals that can be produced from a variety of raw materials such as petroleum, coal and renewable biomass. The production of carboxylic acids by combining olefins, CO2and H2is a sustainable and very promising protocol. However, only a few advances in this topic have been achieved because novel catalysts need to be developed. In this work, we demonstrate that a simple iridium-based catalyst could efficiently promote the synthesis of C2+carboxylic acids via the reaction of olefins with CO2and H2. The reaction was effectively accelerated by a simple iridium-based catalytic system at 170 °C, which may be applied to various olefin substrates. The catalytic mechanism was studied through a series of control experiments. The findings contribute to advancing the sustainable production of valuable products by the reaction of renewable CO2and green H2with platform chemicals.
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危险品化学品经营许可证（带存储）