NEW JOURNAL OF CHEMISTRY
·
2022
·Vol. 47
·期 4
·2079-2085
·
IF 3.925
Shuwen Li,Zhiguo Wang,Siyi Chen,Jialin Gu,Yanping Ma,Jiangang Jiang,Rui Zhang,Dan Zhang,Yiping Wang,He Wang
Based on the internal filtration effect between upconversion nanoparticles and square acid-FeIII(SA-FeIII), this method was developed for the rapid identification of total antioxidant capacity of different fruits without complex modification on the surface of upconversion nanoparticles. The near-infrared light excitation of rare-earth upconversion can effectively avoid food fluorescence and the photobleaching effect; thus, the components to be detected in the samples can be monitored real time without a complex extraction process. Due to the instability of the antioxidants at room temperature, the short time required for this reaction (6 min) will facilitate the study of the true antioxidant power of the samples. This method is simple and responds well to the main antioxidants of fruits and vegetables with a detection limit of 0.1 μmol L−1, such as ascorbic acid, polyphenols, and anthocyanin, and it shows good linearity in the concentration range of 0–1.0 mmol L−1.
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高影响因子
FOOD CHEMISTRY
·
2022
·
IF 9.231
Ying Li,Rida Javed,Rui Li,Yuyang Zhang,Ziyue Lang,Hongbin Zhao,Xing Liu,Hongmei Cao,Daixin Ye
Ascorbic acid is one of the important vitamins to maintain human life activities and plays an irreplaceable role in regulating human redox metabolism. Fresh fruit can provide plenty of AA to maintain human metabolic balance. Thus, it is great significant to develop a rapid and convenient method for detection of AA to evaluate the freshness and nutritional quality of fruits. In this work, Fe single-atom nanoenzyme (Fe-SAN) based colorimetric sensor assisted with smartphone was designed for rapid and on-site AA detection in tropical fruits. Firstly, Fe-SAN with high oxidase-mimicking activity was synthesized by using green tea leaves as sources of carbon and nitrogen and NaH 2 PO 2 as P source to obtain Fe-P/N C SAN, in which P was used to reconstruct the distribution of electronic to enhance the oxidase-mimicking activity of Fe-SAN. Besides, the as-synthesized Fe-P/N C SAN with remarkable oxidase-like activities could oxidize 3,3́,5,5́-tetramethylbenzidine (TMB) to blue colored oxidized TMB. AA could inhibit the oxidation of TMB, leading to blue fading. Based on the above principle, colorimetric sensor integrated with smartphone RGB mode was fabricated and exhibited a good linear detection range (0.5–100 μM) and low detection limit of 0.315 μM for AA detection under optimal conditions. More importantly, the developed sensor could rapidly and accurately detect AA in real sample, such as pineapple, wax apple and mango. Therefore, this research provides a new cost-effective method for the efficient and exact detection of AA in tropical fruit, which has a broad application prospect.
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PubMed
高影响因子
JOURNAL OF CHROMATOGRAPHY A
·
2022
·
IF 4.601
Yang-Ye Zhou,Jia-Ping Chen,Lu Gan,Wen Xu,Yu Liu,Yong-Gang Zhao,Yan Zhu
An analytical method for the detection of glucose in human exhaled breath by non-invasive condensation collection coupled with ion chromatography was developed. A self-designed exhaled breath condensation device was constructed, through which human exhaled breath was condensed and collected. And the glucose in collected human exhaled breath condensate (EBC) was analyzed by ion chromatography with a pulsed amperometric instrument. The standard EBC collection method was established, and the key factors such as cooling temperature and sampling flow rate during condensation collection were investigated deeply, and a good linear correlation between blood glucose levels and exhaled breath glucose levels was obtained. The intra-day precision was 3.37%, and the inter-day precision was 3.83%. Furthermore, EBC from healthy people and diabetic patients was collected in fasting state and after meal. We found the breath glucose level in healthy volunteers was 0.11–2.34 ng/L and that in diabetic patients was 0.23–135.92 ng/L. In after meal samples, the breath glucose level is 10–100 times higher than that of healthy subjects, which offering the prospect of a non-invasive approach to the monitoring of diabetes.
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PubMed
高影响因子
EUROPEAN JOURNAL OF PHARMACOLOGY
·
2022
·
IF 5.195
Yuzhen Lu,Cong Zhang,Yingying Song,Liang Chen,Xin Chen,Guohua Zheng,Yuan Yang,Peng Cao,Zhenpeng Qiu
Accumulating evidence suggests that de novo lipogenesis is a typical characteristic facilitating nonalcoholic fatty liver disease (NAFLD) progression. Gallic acid (GA) is a naturally occurring phenolic acid with metabolic disease-related clinical significance and preclinical benefits. This study aimed to evaluate the anti-steatotic potentials of GA in a fructose-induced NAFLD mouse model featuring a hepatic lipogenic phenotype. The results revealed that GA alleviated hepatic steatosis , oxidative stress , and inflammatory response in fructose-fed mice. Mechanistically, GA treatment restored AMP-activated protein kinase α (AMPKα) phosphorylation, resulting in downregulations of pro-lipogenic factors, including sterol regulatory element binding protein-1 (SREBP-1), fatty acid synthetase (FASN), and acetyl-CoA carboxylase (ACC), in hepatocytes of mice and in vitro . Furthermore, computational docking analysis indicated that GA could directly interact with AMPKα/β subunits to stabilize its activation. These results suggest that GA ameliorates fructose-induced hepatosteatosis by restraining hepatic lipogenesis via AMPK-dependent suppression of the SREBP-1/ACC/FASN cascade. Altogether, this study demonstrates that GA supplement may be a promising therapeutic strategy in NAFLD, especially in the subset with enhanced hepatic lipogenesis.
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Food & Function
·
2022
·Vol. 14
·期 1
·250-261
·
IF 6.317
Wenjie Yu,Fengjie Sun,Ruixin Xu,Meng Cui,Yongquan Liu,Quanyuan Xie,Limin Guo,Chenxian Kong,Xin Li,Xiali Guo,Liping Luo
Castanopsis is diffusely spread in tropical and subtropical regions and is an important nectar source plant in China. The Castanopsis honey (CH) is characterized by its bitter taste. However, its composition and functions remain unclear. In this study, the physicochemical parameters, chemical composition, and antioxidant capacity of CH were comprehensively investigated, with the anti-inflammatory effects of the Castanopsis honey extract (CHE) evaluated based on the RAW 264.7 cell inflammatory model. The results revealed a high level of quality in CH based on the quality standards. Among a total of 84 compounds identified in CH, 5 high response compounds and 29 phenols were further quantified by UPLC-Q/TOF-MS. The high content of phenylethylamine (117.58 ± 64.81 mg kg−1) was identified as a potential marker of CH. Furthermore, the CH showed evident antioxidant activities, and the anti-inflammatory activities of CHE were observed to inhibit the release of nitric oxide (NO) and reduce the content of tumor necrosis factor alpha (TNF-α) and improve the content of interleukin-10 (IL-10) by regulating the NF-κB pathway. Our study indicates that CH has sound physicochemical properties and biological activities with a high level of quality, providing strong experimental evidence to support the further economic and agricultural development and application of CH.
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ELECTROCHIMICA ACTA
·
2022
·
IF 7.336
Weijie Fu,Kai Zhang,Xiaohua Zhang,Guorong Fan,Zongde Wang,Shangxing Chen,Yangping Wen,Peng Wang
Transition metal sulfide functionalized hierarchically porous carbons as colorimetric-electrochemical dual-mode nanozyme sensing platform for the visual qualitative colorimetric and quantitative electrochemical detection of dopamine (DA) are synthesized by hydrothermal method using Chinese fevervine herb rich in sulfur as the carbon source and sulfur source, and different transition metal chlorides as the metal sources. The introduction of FeCl 3 is more favorable to the generation of micropores, while the introduction of other transition metal chlorides is beneficial to the generation of mesopores and macropores. FeS 2 functionalized hierarchically porous carbon (FSPC) with large specific surface area shows better conductivity, more excellent electrocatalytic ability, and higher peroxidase-like and oxidase-like activities. The inhibitory colorimetric assay for DA designed by the oxidase-like properties of FSPC without the intervention of H 2 O 2 , making the reaction system more stable. FSPC displays excellent electrochemical responses for DA with about 50-fold peak current compared with bare electrode, and possesses a low detection limit of 0.015 μM (S/ N = 3) in a wide linear range of 0.05–1000 μM. This work will provide a new idea for the nanozyme sensing of DA with colorimetric-electrochemical dual-mode and a new possibility for application in clinical medicine.
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JOURNAL OF THE INDIAN CHEMICAL SOCIETY
·
2022
·
IF 0.243
Haijian Liu,Zhenxiang Li,Wei Zhang,Ying Liu,Rongkai Pan,Guofu Huang
Carbon nanodots (CDs) with superior fluorescence performance were obtained by hydrothermal method using tomatoes as raw materials. When the ultraviolet absorption band of tartrazine and the fluorescence spectrum of CDs have complementary overlaps, the fluorescent internal filter effect (IFE) occurred. Furthermore, the degree of quenching of fluorescence intensity of CDs has an excellent linear correlation with tartrazine concentration. And based on this principle, a method for detecting tartrazine was established. As the decrease of fluorescence intensity, tartrazine can be measured in the linear range of 0.1 μM–40 μM. The detection limit is 39 nM, and the recovery rate is 90.7%∼114.5%. The established protocol was also effectively employed to assay tartrazine in beverage samples, indicating that it has great potential for food color analysis.
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BIOMASS & BIOENERGY
·
2023
·
IF 6
Jirui Yang,Yanwei Zhang,Feng Shen,Xinhua Qi
Meerwein-Ponndorf-Verley (MPV) reaction has been widely acknowledged to be a mild catalytic transfer hydrogenation method for selective reduction of biomass-derived furfural to furfuryl alcohol . Herein zirconium-containing mesoporous composite catalyst was developed through the combination of sol-gel process and soft templating method, in which naturally abundant glucose and F127 triblock copolymer were used as the ligand and pore-forming agent, respectively. The hydroxyl groups in glucose molecules were demonstrated to be coordinated with zirconium ion during hydrolysis-condensation of zirconium precursor, leading to the even dispersion of zirconia nanoparticles in the composite catalyst. The composite catalyst was proven to be highly efficient for catalyzing MPV reduction of furfural with the maximum furfuryl alcohol yield of 93.4% at 180 °C within 180 min in 2-propanol, which served as both solvent and reductant . The composite also showed a good reusability . After five consecutive reaction cycles, furfuryl alcohol yield was slightly reduced from 93.4% to 77.7%, but it could be recovered to 92.8% after the reused composite was regenerated with dilute alkali solution. Batch experiments and systematic characterizations demonstrated that the excellent catalytic performance of composite catalyst was determined by multiple factors mainly including the stronger Lewis acidity, a considerable amount of basic site and the rich mesoporous structure. This study provides a facile strategy to prepare multifunctional composite catalysts using naturally abundant carbohydrates as the feedstocks for lignocellulosic biorefinery .
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高影响因子
FUEL PROCESSING TECHNOLOGY
·
2022
·
IF 8.129
Xiaowen Ge,Hong Li,Mengyuan Liu,Zhenyu Zhao,Xin Jin,Xiaolei Fan,Xin Gao
Ethoxymethylfurfural (EMF) is a promising fuel additive and biofuel which can be produced via catalytic direct alcoholysis of fructose. In this work, microwave-responsive catalysts were prepared by carbonization of cellulose (via either hydrothermal treatment or calcination) then functionalized with SO 3 H group (via impregnation using concentrated sulfuric acid), which exhibit remarkable performances in one-pot catalytic conversion of fructose to EMF with ethanol. After a 8 h reaction under microwave irradiation at 75 °C, about 80.3% fructose conversion was achieved with the EMF yield of 61.2% for the carbon catalyst prepared by the hydrothermal treatment, which is much higher than that achieved by the catalysis promoted by conventional heating. Further investigation showed that with a microwave-responding catalyst, microwave irradiation encourages the formation of local hot-spots on the catalyst surface, thus facilitating the collision of reactant molecules with catalysts to improve the catalytic efficiency. This work demonstrates the potential of microwave-responsive heterogeneous catalysts for process intensification of valorization of bio-derived chemicals under microwave irradiation.
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CELLULOSE
·
2022
·Vol. 29
·期 2
·879-891
·
IF 6.123
Zhou Liang,Liu Qiyu,Ma Qiaozhi,Guan Mingzhao,Ouyang Xinping,Qiu Xueqing
Abstract Saccharification of cellulose into glucose is a key step for the utilization of lignocellulose. Molten salt hydrate (MSH) is unique in selective hydrolysis of cellulose into glucose but the separation of formed glucose from MSH is challenging due to the high solubility of glucose in MSH. To address this issue, this work developed a method where a small dosage of MSH was applied to impregnate cellulose and convert it into water-soluble sugar with the degree of polymerization (DP) lower than 6, which can be readily hydrolyzed into glucose under mild conditions without sacrificing selectivity. Under the optimized impregnation condition at 110 °C for 2 h, cellulose was selectively converted into water-soluble sugar with a yield of 87.5%. Then the MSH can be efficiently dissolved and removed by anti-solvent isolation with n -butanol, resulting in a sugar recovery of 84.3%. We showed that the separation efficiency was influenced by anti-solvent polarity and oligosaccharides chain-length. Moreover, the production and separation of water-soluble sugar from corn stover was also investigated. 88.9% yield of water-soluble sugar was obtained from the impregnation of corn stover under the optimized reaction conditions. With the addition of n -butanol as an anti-solvent, the water-soluble sugar can be recovered from MSH with a selectivity of 86.7%. Graphical Abstract
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高影响因子
JOURNAL OF MOLECULAR LIQUIDS
·
2022
·
IF 6.633
Shen Zhang,Caidi Jin,Kuichuan Sheng,Ximing Zhang
5-hydroxymethylfurfural (HMF) primary can be synthesized from monosaccharides including glucose and fructose, cost is one of barriers to realize HMF large-scale production. In this study, a high HMF yield of 69.6 mol% was obtained at 180℃ for 5 min using biomass derived cellulose formate as reactant, which was prepared by formylation of cellulose using recyclable formic acid, and sequentially catalyzed by hydrochloric acid (HCl) and aluminum chloride (AlCl 3 ) in dimethyl sulfoxide (DMSO) and H 2 O system. To investigate the effect of cosolvents and formyl groups on the cellulose formate conversion, kinetics analysis and molecular dynamics simulations were conducted. Reaction kinetics study shows that the rate constant of hydrolysis of cellulose formate to glucose increased by almost three times in DMSO-H 2 O and the reaction rates’ constants of glucose, fructose and HMF to humins decreased with the presence of DMSO. Molecular dynamics simulations show that formyl group and DMSO increased its hydrophilicity around the reactive hydroxyl group on the carbon ring and steric hindrance of formyl group affect the distribution of water molecular and DMSO molecular around formylated glucose, resulting in facilitating the formation of a precursor to fructose and inhibiting the formation of humins during formylated glucose conversion.
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高影响因子
ELECTROCHIMICA ACTA
·
2022
·
IF 7.336
Sankar Sekar,Jiang Huijun,Zhou Liuzhu,Chen Jin,Sejoon Lee,Deuk Young Kim,Ramalingam Manikandan
Foodborne antioxidants including ascorbic acid (AA), caffeic acid (CA) and gallic acid (GA) are beneficial nutritional sources and thereby the analysis of the critical antioxidant is demanding for public health. Here, a sonochemical method was used to obtain hybrid copper-phthalocyanine conjugated graphitic carbon nitrides nanosheets (CuPTc/g-C 3 N 4 Ns) in which carboxylic acids and hydroxyl groups were added on the basal plane of g-C 3 N 4 . As prepared materials were characterized by various physicochemical and electroanalytical techniques, the CuPTc/g-C 3 N 4 Ns nanocomposite showed an excellent electrocatalytic activity towards antioxidants quantifications by using Indium Tin Oxide (ITO) coated glass plate. Under optimized experimental conditions, sensitive electrochemical detection of antioxidants was achieved on the CuPTc/g-C 3 N 4 Ns nanocomposite-modified ITO which resulted in wide linear concentration range of 0.05-500 µM (AA), 0.05-501 nM (CA) and 10-445 nM (GA) and the limit of detection (LOD) of 0.006 µM, 0.008 nM and 0.5 nM respectively. Furthermore, the fabricated sensor was successfully used for the antioxidants determinations in different commercial fruit juice, alcoholic beverages and tea samples with good recovery results demonstrating a hybrid phthalocyanine conjugated 2D carbon nanocomposite as an efficient electrocatalyst of desirable practical importance.
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高影响因子
危险品化学品经营许可证（带存储）