SENSORS AND ACTUATORS B-CHEMICAL
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2024
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IF 8
Qian Long,Hanfeng Cui,Jing Zhang,Qiqi Fan,Ting Huang,Hai Shuai,Xiaocui Yin,Guobing Wei,Huanwen Chen,Hao Fan
Cu 2+ serves as a significant biomarker in various physiological processes. This study presents the development of a novel Ru-UiO-TPEA functionalized metal-organic framework (MOFs) probe for Cu 2+ detection, employing both electrochemiluminescence (ECL) and electrochemical (EC) methods. Employing a dual ligand-assisted energy transfer approach, we synthesized Ru-UiO with optimal ECL and EC properties by adjusting the synthesis ratio of biphenyldicarboxylic acid to Ru(dcbpy) 3 2+ . This was followed by its conjugation with N-(2-aminoethyl)-N, N′, N′-tris(pyridin-2-ylmethyl) ethane-1,2-diamine (AE-TPEA) to form the highly conjugated Ru-UiO-TPEA probe for Cu 2+ detection. As the Cu 2+ concentration increased, the probe exhibited a diminished ECL signal and an enhanced differential pulse voltammetry (DPV) signal. The dual-mode detection method enabled cross-validation of the ECL and EC signals, enhancing accuracy and effectively minimizing errors. The ECL and EC methods had detection limits of 0.26 nM (range: 1 nM to 10 μM) and 0.65 nM (range: 2 nM to 80 μM), respectively. Meanwhile, these two methods can effectively detect Cu 2+ in rat brain microdialysis fluid. Notably, the measured concentrations correlated well with those determined by Inductively Coupled Plasma Atomic Emission Spectroscopy (ICP-AES), highlighting its potential in biological and clinical bioelectronic sensing applications.
研究领域:
分析化学
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生物化学
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生物医学工程
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
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2024
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IF 12.2
Xin Liu,Tiehu Li,Yuhui Liu,Yiting Sun,Yanying Han,Tung Chun Lee,Amir Zada,Zeqi Yuan,Fei Ye,Jiahe Chen,Alei Dang
Sensitive and rapid identification of volatile organic compounds (VOCs) at ppm level with complex composition is vital in various fields ranging from respiratory diagnosis to environmental safety. Herein, we demonstrate a SERS gas sensor with size-selective and multiplexed identification capabilities for VOCs by executing the pre-enrichment strategy. In particular, the macro-mesoporous structure of graphene aerogel and micropores of metal-organic frameworks (MOFs) significantly improved the enrichment capacity (1.68 mmol/g for toluene) of various VOCs near the plasmonic hotspots. On the other hand, molecular MOFs-based filters with different pore sizes could be realized by adjusting the ligands to exclude undesired interfering molecules in various detection environments. Combining these merits, graphene/AuNPs@ZIF-8 aerogel gas sensor exhibited outstanding label-free sensitivity (up to 0.1 ppm toluene) and high stability (RSD=14.8%, after 45 days storage at room temperature for 10 cycles) and allowed simultaneous identification of multiple VOCs in a single SERS measurement with high accuracy (error < 7.2%). We visualize that this work will tackle the dilemma between sensitivity and detection efficiency of gas sensors and will inspire the design of next-generation SERS technology for selective and multiplexed detection of VOCs.
研究领域:
材料科学
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分析化学
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环境科学
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生物医学工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ELECTROCHIMICA ACTA
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2018
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IF 5.116
Qian Wang,Liang Shao,Zhonglei Ma,Juanjuan Xu,Ying Li,Caiyun Wang
Metal-Organic Frameworks (MOFs) have attracted increasing attention in the field of energy storage owing to their high porosity, high specific surface area, high charge storage. However, the poor conductivity in most MOFs largely hinders their electrical properties. In this work, we developed an effective strategy to grow the conductive polyaniline (PANI) inside the pores of MIL-101 (labeled as PANI/MIL-101) to form a fixed interpenetrating network structure. The electron-rich imine group in PANI is chelated with the coordinatively unsaturated metal sites (CUS) in MIL-101 to form a relatively strong bonded complex and through other synergistic effects to enhance the conductivity and electrochemical properties. The resultant PANI/MIL-101 exhibited a superior high capacitance of 1197 F g −1 (i.e., 957.6C g −1 ) at 1 A g −1 in constant current charge and discharge test. The assembled flexible solid-state supercapacitor showed a favorable specific capacitance, power density and good cycling stability (a 81% capacitance retention rate over 10,000 cycles). It also demonstrates a good flexibility, as evidenced by a small capacitance loss of 10% after being subject to 1000 bending cycles at 180°. The PANI/MIL-101 nanocomposite showed great potential in energy storage device.
研究领域:
材料科学
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电化学
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能源存储
✓ 已验证
产品关联
DOI
高影响因子
Bioactive Materials
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2023
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IF 18.9
Jianqiu Yang,Zhenzhen Huang,Jiang Tan,Jingye Pan,Shixuan Chen,Wenbing Wan
Bacterial infection and scar formation remain primary challenges in wound healing. To address these issues, we developed a decellularized pomelo peel (DPP) functionalized with an adhesive PVA-TSPBA hydrogel and antibacterial gallic acid/copper MOFs. The hybrid wound dressing demonstrates favorable biocompatibility. It does not impede the proliferation of fibroblasts or immune cells and can stimulate fibroblast migration, endothelial angiogenesis, and M2 macrophage polarization. Additionally, the dressing can scavenge reactive oxygen species (ROS) and provide antioxidant effects. Furthermore, DPP + MOF@Gel effectively inhibits the viability of S. aureus and E. coli in vitro and in vivo. The histological observations revealed enhanced granulation tissue formation, re-epithelialization, and angiogenesis in the DPP + MOF@Gel group compared to other groups. The local immune response also shifted from a pro-inflammatory to a pro-regenerative status with DPP + MOF@Gel treatment. The skin incision stitching experiment further exhibits DPP + MOF@Gel could reduce scar formation during wound healing. Taken together, the hybrid DPP + MOF@Gel holds great promise for treating bacteria-infected skin wounds and inhibiting scar formation during wound healing.
研究领域:
材料科学
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生物医学工程
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伤口愈合
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生物材料
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抗菌剂
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组织工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）