SEPARATION AND PURIFICATION TECHNOLOGY
·
2023
·
IF 8.6
Yi Ren,Die He,Tong Wang,Hong Qi
Organosilica membranes with good hydrothermal stability are promising for pre-combustion capture, but the trade-off effect still constrains their gas separation performance. Herein, we prepared hybrid membranes by incorporating ZIF-7 nanoparticles into 1, 2-bis(triethoxysilyl)ethane (BTESE) networks to improve the H 2 /CO 2 permselectivity by the intrinsic properties of nanoparticles. The effect of inorganic fillers was investigated by adjusting the doping content of ZIF-7 nanoparticles. We found that the H 2 permeance of hybrid membranes remained at ∼10 −6 mol·m −2 ·s −1 ·Pa −1 , while the H 2 /CO 2 permselectivity decreased with increasing nanoparticle doping content. The E-ZIF-7-0.4 hybrid membrane showed H 2 permeance of 1.2 × 10 −6 mol·m −2 ·s −1 ·Pa −1 and H 2 /CO 2 permselectivity of 21.7. Our results may offer valuable insights into preparing hybrid membranes with optimal nanoparticle doping content.
研究领域:
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Weiming Chai,Xia Yu,Yan Lin,Qiu-Han Bai,Yi-Feng Wu,Wen-Jing Wu,Hui-Ying Ou-Yang,Qiu-Xia Pan,Hui-Lin Shu
Browning caused by polyphenol oxidase (PPO) and microorganisms significantly impacts the nutritional quality of fruits and vegetables. This study identified 7-(Diethylamino) coumarin-3-carboxylic acid (7-DCCA) as an effective inhibitor of both PPO and bacteria. Enzyme assays revealed that 7-DCCA competitively inhibits PPO activity with an IC 50 value of 0.275 ± 0.002 mM. Fluorescence and molecular simulation methods demonstrated that 7-DCCA forms a complex with PPO through hydrogen bonding and hydrophobic interactions, altering the enzyme's structure and reducing its activity. Thermogravimetric and differential scanning calorimetry (DSC) assays showed that 7-DCCA stabilizes PPO, delaying its thermal decomposition. Antibacterial tests proved that 7-DCCA inhibits Staphylococcus aureus and Escherichia coli by disrupting cell membranes. Additionally, 7-DCCA suppressed PPO and peroxidase activities, delaying phenolic oxidation and preventing browning in fruits and vegetables. Cytotoxicity assays confirmed its safety, with over 85 % cell viability at concentrations up to 0.1 mM. Stability experiments verified that 7-DCCA had greatly light and thermal stability. This study highlighted 7-DCCA as a promising antibrowning agent with potential application in food preservation.
研究领域:
食品科学
·
生物化学
·
微生物学
✓ 已验证
DOI
PubMed
高影响因子
POLYHEDRON
·
2022
·
IF 2.975
Xian-Hao Feng,Zhi-Chao Yu,Wei Zhang,Carl Redshaw,Timothy J. Prior,Tie-Hong Meng,Chun-Rong Li,Zhu Tao,Xin Xiao
In the work, we have studied the interaction of cucurbit[7]uril (Q[7]) with 1-[4-(dimethylamino)phenyl]-ethanone (DAPE) using a variety of techiniques including 1 H NMR spectroscopy, UV–vis adsorption and fluorescence spectroscopies, Isothermal titration calorimetry and single crystal X-ray diffraction. Results revealed the formation of a 1:1 complex, whilst the molecular structure of the species [(Q[7]@DAPE)Ca(H 2 O) 3 ] 2 (CdCl 4 ) 2 ·31(H 2 O) is reported.
研究领域:
化学
·
分子生物学
✓ 已验证
DOI
高影响因子
Journal of Cleaner Production
·
2024
·
IF 9.7
Jingxin Kang,Huihui Wang,Changjun Zou,Yuqin Li,Jianwei You,Enxing Liu,Wenyue Tang,Yezhong Wang,Bo Wen,Yixuan Cao
The demand for oil and natural gas energy is increasing dramatically, and the extraction of conventional oil and gas reservoirs is in a stage of exhaustion. In order to stabilize the functionalized properties of oil-based drilling fluids (OBDF) during the extraction of oil and gas reservoirs in ultra-deep wells, the present experiments were carried out on the material (EG-NIT/CB[7]) obtained by encapsulating nitrate (NIT) in expanded graphite (EG) with porous structure through the supramolecular self-assembly property of cucurbit[7]uril (CB[7]). The structural properties were analyzed using various analytical tools and the results showed that our material synthesis was successful. And the effect of mass fraction of EG, CB[7] on the heat transfer and storage of EG-NIT and EG-NIT/CB[7] materials was investigated. The increase in mass fraction of EG can increase the thermal conductivity of EG-NIT up to 7.4 times and the introduction of CB[7] further improves the thermal conductivity of EG-NIT/CB[7] by up to 1.38 W/m·k. The latent heat value of EG-NIT/CB[7] decreased by only 4.7% after 200 cycles. Meanwhile, under the condition of 150 °C, adding EG-NIT/CB[7] to drilling fluids can reduce the temperature of drilling fluids by 2.8 °C. And it improves the stability of drilling fluids, the viscosity almost does not change, and it can also play a certain role in inhibiting the leakage of drilling fluids. Therefore, the EG-NIT/CB[7] developed by us can be practically applied in ultra-deep drilling projects.
研究领域:
材料科学
·
能源工程
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2024
·
IF 6.7
Qiuxiang Mao,Lancheng Wang,Dandan Xue,Xiaoxuan Lin,Fang Sun,Pengcheng Xu,Jieru Chen,Wenying Li,Xiuchen Li,Fang Yan,Chi Hu
Although multiple forms of dimers have been described for GPCR, their dynamics and function are still controversially discussed field. Fluorescence microscopy allows GPCR to be imaged within their native context; however, a key challenge is to site-specifically incorporate reporter moieties that can produce high-quality signals upon formation of GPCR dimers. To this end, we propose a supramolecular sensor approach to detect agonist-induced dimer formation of μ-opioid receptors (μORs) at the surface of intact cells. With the macrocyclic host cucurbit[7]uril and its guest hemicyanine dye tethered to aptamer strands directed against the histidine residues, the sensing module is assembled by host–guest complexation once the histidine-tagged μORs dimerize and bring the discrete supramolecular units into close proximity. With the enhanced sensitivity attributed by the “turn-on” fluorescence emission and high specificity afforded by the intermolecular recognition, in situ visualization of dynamic GPCR dimerization was realized with high precision, thereby validating the supramolecular sensing entity as a sophisticated and versatile strategy to investigate GPCR dimers, which represent an obvious therapeutic target.
研究领域:
药理学
·
细胞生物学
·
生物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
APPLIED CATALYSIS B-ENVIRONMENTAL
·
2019
·
IF 14.229
Yanyan Zhao,Yongbo Wang,Xuhua Liang,Huanxian Shi,Cunjin Wang,Jun Fan,Xiaoyun Hu,Enzhou Liu
A visible-light-induced antibiotics degradation system based on a nano-Ag, CsPbBr 3 quantum dot (QDs) and bulk g-C 3 N 4 (CN) ternary assembly (Ag-CsPbBr 3 /CN) has been firstly constructed under an organic phase environment, oleylamine (OLA) and oleic acid (OA) were used as surfactants to stabilize the CsPbBr 3 , l -cysteine was used to facilitate the interaction between nano-Ag, CsPbBr 3 and CN. The new ternary assembly of Ag-CsPbBr 3 /CN composite was used to degrade 7-aminocephalosporanic acid (7-ACA) under visible light irradiation, and the 7%-Ag-CsPbBr 3 /CN composite displayed the superior photocatalytic activity, approximately 92.79% of 7-ACA has been degraded to CO 2 , H 2 O and other small molecules at 140 min, which was approximately 1.49-folds, 1.56-folds, 3.01-folds and 11.43-folds higher than 9%-CsPbBr 3 /CN, 7%-Ag/CN, pure CN and pure CsPbBr 3 , respectively. A possible mechanism for 7-ACA degradation over Ag-CsPbBr 3 /CN composite were proposed according to detailed measurements of adsorption test, Brunauer-Emmett-Teller (BET) measurement, UV–vis diffuse reflectance spectra (DRS), photoluminescence spectra (PL), transient photocurrent response and electrochemical impedance spectroscopy (EIS) measurement, and the enhanced photocatalytic activity of Ag-CsPbBr 3 /CN composite could be attributed to the excellent adsorbability, the enhanced light-harvesting and reduced charge recombination, as well as the synergistic effects of nano-Ag and CsPbBr 3 co-loaded with CN. In addition, Holes (h + ) and hydroxyl radicals ( OH) played major roles, electronic (e − ) and superoxide radical ( O 2 -) played minor roles based on the reactive-species-trapping experiments, the NBT transformation and the 7-hydroxycoumarin fluorescent experiments. Furthermore, a possible 7-ACA degradation pathway was investigated based on the Liquid Chromatography-Mass spectroscopy (LC-MS) experiment to better understand the degradation process. The present opens up a new insight for using CsPbBr 3 as photocatalyst to degrade antibiotics.
研究领域:
环境科学
·
材料科学
·
生物学
✓ 已验证
产品关联
DOI
高影响因子
CERAMICS INTERNATIONAL
·
2018
·
IF 3.057
Junhui Yi,Changquan Jiao,Huimei Mo,Qiujuan Chen,Qining She,Zhilin Li
Flower-like Bi 2 O 3 /Bi 2 MoO 6 heterostructured microspheres with excellent photocatalytic performance were successfully constructed by in situ ion exchange and calcination , employing Bi 2 MoO 6 microspheres prepared by solvothermal method as raw material and template. Various characterization techniques including XRD , FE-SEM, EDS , UV–vis DRS and XPS have been adopted to analyze the composition, structure and optical absorption property of the obtained sample. Their photocatalytic properties for degrading acid orange 7 (AO7) were investigated with visible light. Experimental results show that all Bi 2 O 3 /Bi 2 MoO 6 composites have a higher catalytic activities than pure Bi 2 MoO 6 . Remarkably, 0.2Bi 2 O 3 /Bi 2 MoO 6 show best activity and the degradation efficiency is up to 99% under visible light for 100 min, which is ascribed to the synergistic effect and big heterojunction interface, and promoting rapid transmission of photogenerated charge. Moreover, There is negligible reduction on the degradation efficiency after catalysts was reused for 4 times. The photogenerated holes (h + ) and superoxide radical anions (•O 2 - ) were major active species by radical scavenger experiments. A possible mechanism is proposed to explain rationally enhancement of photocatalytic activity.
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2021
·
IF 3.764
Zi-Ming Zhan,Xin Zhang,Yin-Xin Fang,Yong-Jian Tang,Ka-Ke Zhu,Xiao-Hua Ma,Zhen-Liang Xu
Polyamide nanofiltration (NF) membranes with enhanced desalination and fouling resistance were fabricated via grafting N,N-dimethyl-N-2-propenyl-2-propene-1-ammonium chloride-2-propenamide (polyquaternium-7, PQ7), which consists of dimethyl diallyl ammonium chloride and acrylamide monomers. Compared to the control polyamide NF membrane, the PQ7-grafting membrane exhibited higher hydrophilicity, rougher membrane surface, and stronger positive charge. The surface grafting process had no distinct influence on membrane thickness. After modification, the water flux of the resulting membrane improved from 47.8 to 79.6 L m–2 h–1 under 5 bar, showing a significant improvement in permeability. Meanwhile, the rejection to divalent ions was elevated to a superior level due to the introduction of the positively charged quaternary ammonium groups from PQ7. Furthermore, the antifouling evaluation indicated that the modified polyamide NF membrane owed superior flux recovery capacity and fouling resistance to both sodium alginate solution and bovine serum albumin. Owing to the low cost of the surface modifier and facile grafting process, this strategy has wide application potential in fabricating superior NF membranes used for water softening.
研究领域:
材料科学
·
环境工程
·
水处理技术
✓ 已验证
产品关联
DOI
高影响因子
SAUDI PHARMACEUTICAL JOURNAL
·
2017
·
IF 2.302
Yubin Ji,Miao Yu,Zheng Qi,Di Cui,Guosong Xin,Bing Wang,Weiling Jia,Lin Chang
As research was conducted on the early apoptosis of human breast cancer cell MCF-7 caused by lycorine hydrochloride and the expression of the related apoptosis proteins. The early-period apoptosis rate of human breast cancer cell MCF-7 was tested with the AnnexinV/PI double staining and flow cytometry. The Western Blotting method was also used to detect the protein expression conditions of Fas, FasL, Caspase-8 and Bid. The results showed that the higher the dose, the higher the rate of apoptosis and that the rate of apoptosis was dependent on the dose; the relative protein activity of Fas, FasL, Caspase-8 and bid gradually rose with the increase of lycorine dosage and the activities revealed certain dose-independence. Results showed that lycorine hydrochloride could induce the apoptosis of human breast cancer cell MCF-7 through the death receptor pathway.
研究领域:
肿瘤学
·
分子生物学
·
药理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF INORGANIC BIOCHEMISTRY
·
2011
·
IF 3.317
Li-Jun Tang,Xiang Chen,Yu-Na Sun,Jia Ye,Jing Lu,Ying Han,Xing Jiang,Chan-Chan Cheng,Cheng-Cheng He,Pei-Hong Qiu,Xiao-Kun Li
A new series of complexes of a ligand 4′, 7, 8-trihydroxy-isoflavone with transition metal (zinc, copper, manganese, nickel, cobalt) and selenium have been synthesized and characterized with the aid of elemental analysis , IR, electron ionization mass spectrum (EI-MS) and 1 H NMR spectrometric techniques . The compounds were evaluated for their in vitro antibacterial activities and antitumor properties. The metal complexes were found to be more active than the free ligand. Investigation on the interaction between the complexes and calf-thymus DNA (CT DNA) showed that the absorbance of CT DNA increased and the maximum peak (λ max = 260 nm) red-shifted, while the intensity of fluorescence spectra of Epstein-Bart DNA (EB-DNA) gradually weakened, which indicated that all of these metal complexes tightly combined with CT DNA.
研究领域:
生物化学
·
药物化学
·
分子生物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
NEW JOURNAL OF CHEMISTRY
·
2018
·Vol. 43
·期 1
·407-412
·
IF 3.201
Pei-Hui Shan,Zhi-Rui Zhang,Dong Bai,Bing Bian,Zhu Tao,Xin Xiao
The interactions between inverted cucurbit[7]uril (iQ[7]) and six biogenic amines, namely tyramine (TA), 2-phenylethylamine (PEA), histamine (HI), tryptamine (TR), spermine (SPM), and spermidine (SPD), were studied through 1H nuclear magnetic resonance (NMR) spectroscopy, UV/vis absorption spectroscopy, fluorescence spectroscopy, isothermal titration calorimetry (ITC), and matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS). The results showed that iQ[7] exhibits binding affinity towards five of these biogenic amines, with the exception of HI, and that the host–guest binding sites differ depending on the structure of the biogenic amine. For the aromatic amines (TA and PEA), the phenyl groups are completely encapsulated within iQ[7]; for the heterocyclic aromatic amine TR, there is deep inclusion of its indole group in the cavity of iQ[7]; for the fatty amines (SPM and SPD), the central alkyl chain is bound within the central cavity of iQ[7].
研究领域:
化学
·
生物学
·
医学
✓ 已验证
DOI
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2020
·
IF 3.232
Shasha Feng,Jingjing Lv,Fubin Pei,Xuchu Lv,Yi Wu,Qingli Hao,Yuehua Zhang,Zhaoyang Tong,Wu Lei
A novel method for turn-off sensing 1,1-diamino-2,2-dinitroethylene (FOX-7) in aqueous medium was first proposed based on the inner filter effect (IFE) of FOX-7 on the fluorescence of molybdenum disulfide quantum dots (MoS 2 QDs). Water-soluble MoS 2 QDs as the fluorophore were prepared by the simple hydrothermal method . The morphology, structure, composition and optical properties of the prepared MoS 2 QDs were characterized by Transmission electron microscopy (TEM), Fourier transform infrared (FT-IR), X-ray photoelectron spectroscopy (XPS), UV–vis absorption and photoluminescence spectra. The results showed that the MoS 2 QDs had good water dispersibility and emitted strong photoluminescence with a particle size of 2 nm. Under the optimal experimental conditions, the fluorescence signal of MoS 2 QDs was quenched in the concentrations range of FOX-7 (0.5–100 μM) and the limit of detection (LOD) of the sensor was 0.19 μM. The method had been applied to analyze the real water samples with good selectivity and stability. Moreover, the quenching mechanism was studied systematically by the Fourier transform infrared (FT-IR), UV–vis absorption spectra, fluorescence lifetime , and Stern-Volmer equation, which had been proved to be static quenching. The fluorescence quenching mechanism is mainly IFE and electron transfer.
研究领域:
分析化学
·
材料科学
·
环境科学
✓ 已验证
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）