JOURNAL OF APPLIED POLYMER SCIENCE
·
2017
·Vol. 134
·期 26
·
IF 1.86
Fangqiao Zhao,Xiaoma Fei,Wei Wei,Weitao Ye,Jing Luo,Yaxin Chen,Ye Zhu,Xiaoya Liu
Toughening of epoxy resin by block copolymers containing an epoxy-philic block and an epoxy-phobic block is usually costly because of their complex preparation procedure. In this work, a novel, random epoxy-amphiphilic copolymer (PHGEL), which combines an “epoxy-philic” component and an “epoxy-phobic” component, has been synthesized and evaluated as a potential toughening agent for a diglycidyl ether of bisphenol A–based epoxy thermoset (EP). The curing behavior of the EP/PHGEL system has been investigated, and the results show that the hydroxyl group on the PHGEL chain can slightly activate the curing reaction. The mechanical testing shows that the toughness of the epoxy resin is improved by 294% when 4 wt % of PHGEL is added. Simultaneously, the tensile strength, elongation at break, and glass-transition temperature are also improved. In addition, the thermogravimetric analysis shows that PHGEL has no obvious effect on the thermal stability of the epoxy thermosets. © 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2017 , 134 , 44863.
研究领域:
材料科学
·
高分子化学
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DOI
高影响因子
Materials Chemistry Frontiers
·
2021
·Vol. 5
·期 18
·7032-7040
·
IF 6.482
Xiaojia Jiang,Mingsong Zang,Fei Li,Chunxi Hou,Quan Luo,Jiayun Xu,Junqiu Liu
Recently, biological nanopore-based techniques have attracted more and more attention in the field of single-molecule detection because they allow real-time, sensitive, high-throughput analysis. Herein, we report an engineered biological nanopore sensor by introducing a macrocyclic host molecule carboxylatopillar[5]arene (CP[5]A) that acts as an aptamer into the lumen of a mutant (E111R/K147R)7 αHL nanopore for detecting highly toxic paraquat (PQ) via host–guest interactions at the single-molecule level. By taking advantage of introducing positively charged arginine (Arg) into the lumen of the αHL nanopore, our engineered nanopore sensor exhibits higher stability. More importantly, this nanopore sensor shows high sensitivity, and the limit of detection (LOD) for PQ can reach a nanomolar level of 0.37 ppb. The CP[5]A-based nanopore sensing strategy developed in this work may bring inspiration for single-molecule detection and hold great potential in public health applications.
研究领域:
纳米技术
·
分析化学
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生物技术
·
毒理学
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DOI
高影响因子
TRENDS IN BIOTECHNOLOGY
·
2026
·
IF 16.6
Ruoxi Wang,Aiying Tong,Haishuang Zhu,Donghu Lin,Jiarong Cui,Xiaoyang Liu,Jia Dong,Jin Yang,Min Zhou
Rheumatoid arthritis (RA) is linked to gut barrier dysfunction and microbiota dysbiosis. We developed an oral Spirulina platensis -based hydrogel (SP-gel) with favorable physicochemical properties (gastric retention-intestinal sustained release). In vitro , SP-gel restored intestinal barrier integrity and alleviated inflammation. In vivo , oral SP-gel (especially combined with intra-articular hyaluronic acid) ameliorated joint inflammation, bone erosion, and cartilage degradation in collagen-induced arthritis mice. Mechanistically, SP-gel reinforced the gut barrier, rebalanced immunity (regulatory T/t helper 17 cells) and remodeled gut microbiota. It also showed good biosafety and enhanced methotrexate efficacy. Our findings highlight SP-gel’s potential as a safe oral adjuvant therapy for RA targeting the gut–joint axis.
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DOI
PubMed
高影响因子
TALANTA
·
2024
·
IF 5.6
Xiaojin Luo,Jiaye Xie,Li Yang,Yue Cui
In order to improve the living standards of diabetes patients and reduce the negative health effects of this disease, the medical community has been actively searching for more effective treatments. In recent years, an artificial pancreas has emerged as an important approach to managing diabetes. Despite these recent advances, meeting the requirements for miniaturized size, accurate sensing and large-volume pumping capability remains a great challenge. Here, we present a novel miniaturized artificial pancreas based on a long microtube sensor integrated with an ultrasonic pump. Our device meets the requirements of achieving both accurate sensing and high pumping capacity. The artificial pancreas is constructed based on a long microtube that is low cost, painless and simple to operate, where the exterior of the microtube is fabricated as a glucose sensor for detecting diabetes and the interior of the microtube is used as a channel for delivering insulin through an ultrasonic pump. This work successfully achieved closed-loop control of blood glucose and treatment of diabetes in rats. It is expected that this work can open up new methodologies for the development of microsystems, and advance the management approach for diabetes patients.
研究领域:
生物医学工程
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医疗器械
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糖尿病研究
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产品关联
DOI
PubMed
高影响因子
Microorganisms
·
2025
·Vol. 13
·期 3
·612
·
IF 4.2
Wenming Wang,Liling Xie,Lin Zhao,Qilin Yu
Alum mining leads to significant heavy metal and acid pollution within soils. Phytoremediation is a common strategy used to treat alum mine soils, but its efficiency is frequently compromised by the alum-mining-induced impairment of plant growth. To improve the strength of plants against mine pollution, this study constructed the artificial yeast strain ScHB (heavy metal-binding protein-containingSaccharomyces cerevisiae) expressing the de novo designed protein HBGFP (heavy metal-binding green fluorescence protein) and investigated its effect on the phytoremediation of alum mine soils with soil physiochemical assays and heavy metal quantification. This protein was composed of an N-terminal signal peptide, an HB (heavy metal-binding) domain, and a GFP (green fluorescence protein) domain, as well as a C-terminal glycolphosphatidylinositol-anchoring fragment. The exposure of the HBGFP on the ScHB surface increased the growth rate of the yeast cells and enhanced cadmium capture from the cadmium-containing medium. After culturingMedicago sativain the alum mine soils for 30 days, ScHB remarkably increased the plants’ average height from 17.5 cm to 27.9 cm and their biomass from 3.03 g/plant to 4.35 g/plant, as well as increasing the accumulation of antioxidant agents in the plants. Moreover, the ScHB cells strongly improved the soil quality, with an increase in the soil pH values from 5.47 to 6.21 to 6.9, and increased the levels of soil organic matter, total nitrogen, available phosphorus, and living bacteria. Furthermore, ScHB efficiently improved the plants’ abilities to remove soil heavy metals, decreasing the levels of cadmium, lead, chromium, and copper by 90%, 86%, 97%, and 88%, respectively. This study developed a genetic engineering method to improve the efficiency of phytoremediation against pollution from alum mining.
研究领域:
环境科学
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遗传工程
·
植物学
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产品关联
DOI
PubMed
高影响因子
Nature Communications
·
2026
·
IF 18.1
Chen Hui,Feng Shuo,Wang Yutong,Zhong Leheng,Liang Wei,Shi Kangning,Li Dedi,Zhu Jiaxiong,Cui Huiling,Tang Zijie,Zhang Haofan,Li Ran,Zhi Chunyi,Lyu Haiming Lv
The electrolytes of aqueous batteries are mostly acidic or alkaline, resulting in inevitable side reactions. More importantly, when batteries are disposed of, strongly acidic and alkaline solutions harm the environment. In this study, we synthesized covalent organic polymers as negative electrode materials for aqueous divalent ion (Mg 2+ and Ca 2+ ) storage, which exhibit favorable performance in electrolytes with a pH of 7.0 (the electrolytes are environmentally benign and can even be “brine” in tofu production). Polymers containing electron-donating linking bonds exhibit fast kinetics and low potential for use in aqueous Mg 2+ /Ca 2+ batteries. In neutral electrolytes (pH = 7.0), Hexaketone-tetraaminodibenzo-p-dioxin covalent organic polymers exhibit 120,000 cycles and deliver specific capacities (up to 112.8 mA h g -1 ). The negative electrode was paired with a positive electrode, creating a full cell that has a voltage interval of 2.2 V and achieves a specific energy of up to 48.3 Wh kg -1 , which is calculated on the basis of the total mass of the negative electrode, positive electrode, and electrolyte at the full cell level, together with long-term cycling stability over 120,000 cycles at a specific current of 20 A g -1 . The full cells are environmentally benign and nontoxic and can be directly discarded to environments according to various standards (GB 18599-2020, ISO 14001, Resource Conservation and Recovery Act RCRA, US).
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DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2020
·
IF 10.652
Chi Yang,Zhijun Wang,Yinhua Lv,Ruihan Yuan,Yihui Wu,Wen-Hua Zhang
The ionic nature of perovskites leads to abundant defects at the interface and grain boundaries of perovskite films, which are detrimental to the performance of perovskite solar cells (PSCs). Here, I-I-VI group CsCu 5 S 3 (CCS) nanocrystals (NCs) were used as an interlayer between the perovskite film and hole transport layer in PSCs. The CCS NCs were synthesized via a facile colloidal chemistry approach and exhibited high air stability and strong absorption in the visible-to-near infrared range. The CCS interlayer effectively passivates the interfacial defects, which strongly suppresses non-radiative recombination in the PSCs. The CCS interlayer is favorable for energy levels between the perovskite and HTM to reduce carrier recombination. As a result, the devices with a CCS interlayer delivered a champion power conversion efficiency (PCE) of 22.29% with good reproducibility and stability. In addition, the PSCs retained more than 85% of their original efficiency after storage for approximately 3000 h under ambient conditions. This work paves a new avenue for the development of high-efficiency PSCs and the application of Cu-based chalcogenide NCs.
研究领域:
材料科学
·
能源技术
·
光电转换
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产品关联
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2023
·
IF 6.7
Ange Nsilani Kouediatouka,Qi Liu,Fagla Jules Mawignon,Wei Wang,Jiawei Wang,Chunbiao Ruan,Kanfolo Franck Herve Yeo,Guangneng Dong
In this paper, a polymer blend labeled PDMS/Ecoflex (PE) was fabricated using Polydimethylsiloxane (PDMS) and Ecoflex 00-30 in various proportions. An innovative carbon nanotube/carbon black (CNT/CB) hybrid filler reinforced cetyltrimethylammonium bromide (CTAB) surfactant was prepared and sprayed to obtain CNT/CB/PE composite material. The resulting PE blend matrix showed excellent mechanical properties, including high stretchability of nearly 500% strain, minimal hysteresis, and reduced friction by up to 75% with decreasing wear. These properties were attributed to the combined effect of Young’s modulus, stiffness, and hardness of PDMS and Ecoflex. Additionally, three types of contacts CNT-CB, CB-CB, and CNT-CNT were produced by the favorable interaction of CNT and CB particles, stabilizing the sensor signal. The CNT/CB/PE sensor had an improved wear resistance, conductivity stabilization, stretchability, gauge factor during the tensile test, and strain-dependent sensitivity across a broad range of fixed strains (up to 100% strain). Furthermore, the sensor was attached to various human body joints to track the related human motions, proving the fascinating perspective in detecting various human movements and making it appropriate for application in multifunctional wearable devices in hostile environments.
研究领域:
材料科学
·
传感器技术
·
生物医学工程
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产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2023
·
IF 9.5
Huijing Li,Long Li,Hao Zhang,Junjie Wei,Zhenyu Xu,Tao Chen
To make soft robotics intelligent, dazzling artificial skin and actuators have been created. However, compared to rigid commercial robots, the sophisticated demands of raw materials become a key challenge for autonomous soft actuators to realize manufacturing repeatability and reproducibility. Inspired by the stem cell, which has the potential to differentiate into multifunctional cells with the same original compositions, a potential multifunctional gel is presented. With well-designed polymer chains, the gel has a salt-induced regulating module, conductivity, and other bionic properties. Making use of this advantage, the gel acts as a double-duty electrode for both the actuator and sensor. An artificial reflex arc is therefore formed by their tight integration via an e-brain: a computing unit that specifically responds to organism intervention. This efficient strategy to obtain diverse components with minimal raw materials is promising for effortlessly fabricating fully soft robotics.
研究领域:
材料科学
·
生物工程
·
机器人学
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产品关联
DOI
PubMed
高影响因子
Journal of Materials Chemistry C
·
2020
·Vol. 8
·期 20
·6869-6876
·
IF 7.059
Yujie Yan,Xiaomin Wu,Qizhen Chen,Xiumei Wang,Enlong Li,Yuan Liu,Huipeng Chen,Tailiang Guo
Neuromorphic devices represent the essential components for the future artificially intelligent and biomimetic electronics. However, the reported neuromorphic devices only mimic the electronic behaviors of biological synapses while lacking the corresponding physical biomimetic properties, particularly healable capability similar to that of living tissues, which poses a key compatibility limitation for their practical applications. Here, for the first time, we have constructed an intrinsically healing synaptic device, wherein both the channel layer and the electrolyte heal at ambient conditions by utilizing an intrinsically healed semiconducting material and dielectric material. Such devices are capable of efficiently restoring their mechanical and electrical performances after encountering substantial catastrophic damage. More importantly, the essential functionalities of synapses such as paired-pulse depression, spike-timing-dependent plasticity, and spike-voltage-dependent depression as well as depression adaptation behaviors are also well-retained in this artificial synaptic device after completely cutting followed by healing. In this study, for the first time, we have reported the healing neuromorphic synaptic device, shedding light on the future development of more bioinspired humanoid robots, bioimplantable neural prosthetics, exoskeletons, and cybernetic devices integrated with biological and artificial organs.
研究领域:
材料科学
·
神经科学
·
人工智能
·
仿生学
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DOI
高影响因子
Chinese Physics B
·
2021
·Vol. 30
·期 7
·077403
·
IF 1.494
Chengchao Xu,Hong Wang,Huanfang Tian,Youguo Shi,Zi-An Li,Ruijuan Xiao,Honglong Shi,Huaixin Yang,Jianqi Li
Discovery of a new superconductor with distinct crystal structure and chemistry often provides great opportunity for further expanding superconductor material base, and also leads to better understanding of superconductivity mechanisms. Here, we report the discovery of superconductivity in a new intermetallic oxide Hf3Pt4Ge2O synthesized through a solid-state reaction. The Hf3Pt4Ge2O crystallizes in a cubic structure (space group Fm-3m) with a lattice constant of a = 1.241 nm, whose stoichiometry and atomic structure are determined by electron microscopy and x-ray diffraction techniques. The superconductivity at 4.1 K and type-II superconducting nature are evidenced by the electrical resistivity, magnetic susceptibility, and specific heat measurements. The intermetallic oxide Hf3Pt4Ge2O system demonstrates an intriguing structural feature that foreign oxygen atoms can be accommodated in the interstitial sites of the ternary intermetallic framework. We also successfully synthesized a series of Hf3Pt4Ge2O1 + δ (–0.25 ≤ δ ≤ 0.5), and found the δ-dependent superconducting transition temperature Tc. The atomic structure and the electronic structure are also substantiated by first-principles calculations. Our results present an entirely new family of superconductors with distinct structural and chemical characteristics, and could attract research interest in further finding new superconductors and exploring novel physics pertaining to the 5d-electron in these intermetallic compound systems.
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DOI
高影响因子
Nature Communications
·
2026
·Vol. 17
·期 1
·9522
·
IF 18.1
Zhou Junhong,Han Xu,Huang Haibin,Huang Taotao,Wang Yaowen,Woodfield Brian F.,Li Liping,Li Guangshe
Photomagnetism enables optical control of spin order for engineering non-equilibrium phases, yet studies remain largely confined to ferromagnetic systems. Here, we introduce the alterlattice, an emergent structural motif realized in the cation- and anion-deficient perovskite oxide La 0.4 Ca 0.4 TiO 3–δ . The alterlattice is a three-dimensional alternately patterned superstructural network arising from structural competition, in which average lattice is described by Ibmm symmetry while local superstructure relaxes toward Cmmm symmetry. Within this motif, photo-induced antiferromagnetic correlations develop below 19 K. Under 473 nm illumination, the susceptibility of the alterlattice host decreases by 51.7% at 2 K and 1 T and rapidly recovers in the dark. The observed giant negative photomagnetism is associated with anisotropic strain fields that guide defect-mediated photocarrier transport, thereby driving the system from a spin-dilute paramagnetic state toward a short-range antiferromagnetic state with quasi-one-dimensional characteristics. The alterlattice opens a route to three-dimensional defect-topology engineering for non-equilibrium phases and antiferromagnetic spintronics.
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DOI
高影响因子
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