SENSORS AND ACTUATORS B-CHEMICAL
·
2020
·
IF 7.1
Jian Zhang,Yuyu Zhang,Jayne Wu,Haochen Qi,Meiqi Zhao,Maoxiang Yi,Zhenmin Li,Lei Zheng
Cadmium ion (Cd 2+ ) is a highly toxic heavy metal pollutant with long biological half-life and strong bioaccumulation, which may cause irreversible damage to human health even at low-dose intake. Sensitive and specific detection of ultra-trace Cd 2+ is of great significance in food safety and environmental monitoring. In this work, a simple-to-use aptasensor to rapidly detect Cd 2+ in various liquid media is developed based on a DNA aptamer modified gold interdigitated electrode (IDE). Capacitance at the solid-liquid interface is utilized to reflect the change caused by adsorbed Cd 2+ . With the microfluidic enrichment by AC electrothermal (ACET) effect, Cd 2+ ions are sped up toward the IDE surface and captured by the probes instantaneously. Owing to the integration of target enrichment and capacitance detection, the sample-to-result time of this sensor is as short as 30 s. This aptasensor as a quantitative detector has a linear response range from 0.45 fM to 4.5 pM, with a limit of detection of 253.16 aM. The selectivity ratio reaches 2320: 1 against non-target metal ions. By detection of Cd 2+ spiked in tap water and olive oil as well as natural residual Cd 2+ in rice leaching solution, the sensor’s applicability and reliability in different practical liquid media are demonstrated.
研究领域:
环境科学
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分析化学
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食品安全
·
生物技术
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DOI
高影响因子
ENVIRONMENTAL POLLUTION
·
2023
·
IF 8.9
Siyu Zhang,Changdong Ke,Mengge Jiang,Yuancheng Li,Weilin Huang,Zhi Dang,Chuling Guo
Efficient remedies for living organisms including bacteria to counteract cadmium (Cd 2+ ) toxicity are still highly needed. Plant toxicity studies have showed that exogenous S(-II) (including hydrogen sulfide and its ionic forms, i.e., H 2 S, HS − , and S 2− ) application can effectively alleviate adverse effects of Cd stress, but whether S(-II) could mitigate bacterial Cd toxicity remains unclear. In this study, S(-II) was applied exogenously to Cd-stressed Shewanella oneidensis MR-1 and the results showed that S(-II) can significantly reactivate impaired physiological processes including growth arrest and enzymatic ferric (Fe(III) reduction inhibition. The efficacy of S(-II) treatment is negatively correlated with the concentration and time length of Cd exposure. Energy-dispersive X-ray (EDX) analysis suggested the presence of cadmium sulfide inside cells treated with S(-II). Both compared proteomic analysis and RT-qPCR showed that enzymes associated with sulfate transport, sulfur assimilation, methionine , and glutathione biosynthesis were up-regulated in both mRNA and protein levels after the treatment, indicating S(-II) may induce the biosynthesis of functional low-molecular-weight (LMW) thiols to counteract Cd toxicity. Meanwhile, the antioxidant enzymes were positively modulated by S(-II) and thus the activity of intracellular reactive oxygen species was attenuated. The study demonstrated that exogenous S(-II) can effectively alleviate Cd stress for S. oneidensis likely through inducing intracellular trapping mechanisms and modulating cellular redox status. It suggested that S(-II) may be a highly effective remedy for bacteria such as S. oneidensis under Cd-polluted environments.
研究领域:
微生物学
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环境科学
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生物化学
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产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2023
·
IF 8.4
Yue Wang,Hongguo Zhai,Qi Guo,Yuhao Zhang,Xia Sun,Yemin Guo,Qingqing Yang,Yanyan Zhang
Heavy metals and foodborne pathogens have become key pollutants that harm aquatic products, seriously endangering food safety and human health. Therefore, in this study, a ratiometric electrochemical aptamer sensor with a novel signal amplification strategy was constructed using ZrO 2 as the substrate and Ni/Co-MOFs@AuNPs cubic nanomaterials to increase the specific surface area to simultaneously detect Cd 2+ and S.aureus. The shared hairpin complementary chains modified with ferropene (Fc) could simultaneously bind to the Cd 2+ and S.aureus aptamers modified with methylene blue (MB) and anthrquinone-2-carboxylic acid (AQ). The ratios of MB and AQ to Fc were used to realize the qualitative and quantitative detection of Cd 2+ and S.aureus. Under the optimal conditions, the electrochemical aptamer sensor for Cd 2+ and S.aureus was in the range of 1.00 × 10 −2 -1.00 × 10 4 ng/L and 1.00 × 10 1 -1.00 × 10 7 CFU/mL, and the lowest detection limit was 1.91 × 10 −4 ng/L and 1.37 CFU/mL, respectively. The aptasensor constructed in this paper can realize the simultaneous detection of Cd 2+ and S.aureus in scallop and fish, providing a new detection method for the simultaneous detection of a variety of aquatic products pollutants.
研究领域:
分析化学
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环境科学
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食品科学
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产品关联
DOI
高影响因子
Nanoscale Advances
·
2022
·Vol. 5
·期 5
·1416-1424
·
IF 5.598
Hao Wang,Zhuang Hao,Cong Huang,Feiran Li,Yunlu Pan
The discharge of oily industrial wastewater containing heavy metal ions with the development of industry severely threatens the environment and human health. Therefore, it is of great significance to monitor the concentration of heavy metal ions in oily wastewater quickly and effectively. Here, an integrated Cd2+ monitoring system consisting of an aptamer-graphene field-effect transistor (A-GFET), oleophobic/hydrophilic surface and monitoring-alarm circuits was presented for monitoring the Cd2+ concentration in oily wastewater. In the system, oil and other impurities in wastewater are isolated by an oleophobic/hydrophilic membrane before detection. The concentration of Cd2+ is then detected by a graphene field-effect transistor with a Cd2+ aptamer modifying the graphene channel. Finally, the detected signal is collected and processed by signal processing circuits to judge whether the Cd2+ concentration exceeds the standard. Experimental results demonstrated that the separation efficiency of the oleophobic/hydrophilic membrane to an oil/water mixture was up to 99.9%, exhibiting a high oil/water separation ability. The A-GFET detecting platform could respond to changes in the Cd2+ concentration within 10 min with a limit of detection (LOD) of 0.125 pM. The sensitivity of this detection platform to Cd2+ near 1 nM was 7.643 × 10−2 nM−1. Compared with control ions (Cr3+, Pb2+, Mg2+, Fe3+), this detection platform exhibited a high specificity to Cd2+. Moreover, the system could send out a photoacoustic alarm signal when the Cd2+ concentration in the monitoring solution exceeds the preset value. Therefore, the system is practical for monitoring the concentration of heavy metal ions in oily wastewater.
研究领域:
环境科学
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分析化学
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纳米技术
·
水处理
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产品关联
DOI
PubMed
高影响因子
Analytical Methods
·
2014
·Vol. 7
·期 2
·472-477
·
IF 1.938
Meng Li,Da-Wei Li,Yi-Tao Long
We developed a hybrid method combining an electrochemical technique and fluorescence measurement to detect Cd2+ in water samples. The electrochemical deposition and stripping technique provided a clean and selective pretreatment for transferring and concentrating Cd2+ from original turbid samples to blank buffer, followed by fluorescence quantification. Cd2+ in the original samples was co-deposited with Bi3+, which could provide a fresh bismuth film and concentrate a higher amount of Cd2+ onto a portable screen-printed electrode. The water-soluble compound Fura-2 was introduced as the fluorescent indicator for Cd2+ quantification, with the purpose of eliminating the error caused by the transfer to buffer. The detection results using real samples exhibited an excellent anti-interference ability, and showed a good linear correlation (correlation coefficient of R = 0.993). Moreover, the system was highly sensitive as a detection limit of 1.0 nmol L−1 could be achieved through a repeated electrochemical pretreatment process. This hybrid method is selective, sensitive, convenient and portable. It is promising for in field heavy metal ion determination in remote environments.
研究领域:
分析化学
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环境科学
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电化学
·
光谱学
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DOI
高影响因子
CHEMISTRY AND ECOLOGY
·
2017
·
IF 1.463
Haixia Zhan,Jinping Zhang,Zhu Chen,Yongjie Huang,Teija Ruuhola,Shiyong Yang
Cadmium (Cd) is a toxic non-essential element accumulated easily in living organisms due to its non-biodegradable nature. A slight increase in Cd levels will threaten the health of terrestrial and aquatic organisms. Therefore, Cd contamination and its effects on the ecosystems and organisms have become a major topic of eco-toxicological research. The present study investigated the eco-toxicological effects of Cd-supplemented diet on some life history traits and specific enzyme activities of carboxylesterase (CarE), glutathione S-transferase (GST), acetylcholinesterase (AChE) and cytochrome P450 monooxygenases (P450s) in the cotton bollworm, Helicoverpa armigera. The results showed that Cd significantly decreased larval survival, pupation and emergence, and reduced body mass of the sixth instar larvae, pupae, adult moths and female fecundity. Cd-supplemented diet also delayed the development of larvae and pupae and shortened the life span of the cotton bollworm moth. In addition, dietary Cd inhibited the activities of GST, CarE and P450, but increased AChE activity of the sixth instar larvae. We concluded that life history traits and metabolic enzymes are sensitive to Cd stress in the cotton bollworm. These parameters are potential biomarkers for monitoring environmental stress in Lepidopteran insect pests.
研究领域:
生态毒理学
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昆虫学
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环境科学
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产品关联
DOI
高影响因子
Journal of Materials Chemistry C
·
2022
·Vol. 10
·期 46
·17512-17520
·
IF 8.067
Jizhong Liu,Hui Fu,Zhentao Du,Deliu Ou,Shixian Li,Qiaochu Chen,Weiyou Yang,Jialong Zhao,Jinju Zheng
The photothermal stability against light irradiation and high temperature of organic–inorganic hybrid perovskite nanocrystals (PNCs) is critically important for their applications in photoelectronic nanodevices. In the present work, we report the significantly enhanced photothermal stability of FAPbBr3 PNCs, which are fabricated by in situ growth of PNCs in polyvinylidene fluoride films (FAPbBr3@PVDF) with incorporation of Cd2+ ions. It is found that the introduced Cd2+ ions could effectively passivate the PNC defects and shorten the length of Pb–Br bonds, giving rise to the intensified interaction between Pb2+ and Br− in the [PbBr6]4− octahedron, which thereby suppresses the halogen ion migration under light irradiation and high temperature with enhanced photothermal stability. As a result, the Cd2+-doped FAPbBr3@PVDF film exhibits durable photothermal stability with 96% and 97% photoluminescence quantum yield (PLQY) retentions, under continuous blue-light irradiation (460 nm, 13 mW cm−2) for over 360 h, and under both a high temperature of 333 K and blue-light irradiation over 48 h, respectively. Furthermore, the as-constructed white light-emitting-diodes (WLEDs) deliver a wide color gamut (117% of NTSC standard) with chromaticity coordinates of (0.331, 0.337), verifying their promising applications in backlight sources.
研究领域:
材料科学
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纳米技术
·
光电技术
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DOI
高影响因子
CHEMICAL PAPERS
·
2023
·Vol. 77
·期 12
·7577-7587
·
IF 2.2
He Jintao,Zhang Baozhong,Tian Panpan,Li Ying,Liu Xiaolong,Ma Xinyue,Lin Min,Zhu Huina,Chen Hanyu,Li Liping,He Baoshan
Cadmium (Cd), a typical heavy metal not essential for the human body, can cause harm to the liver and kidneys upon exposure. Hence, rapid cadmium detection in the environment is of utmost importance. This research presents an effective approach for detecting divalent cadmium ions (Cd 2+ ) using a sensitive dual hairpin (HP) electrochemical aptasensor. The aptasensor incorporates AuPd/Fe-MOF as signal labels and Au/Cu 2 O as the substrate material, and the rapid detection of divalent cadmium ions (Cd 2+ ) was based on catalytic hairpin self-assembly (CHA), as the recognition strategy. Au/Cu 2 O increased the specific surface area of the electrode and provided abundant sites for capturing the complementary deoxyribonucleic acid (CDNA) probe. The electrochemical signal is then amplified through synergistic catalytic hydrogen peroxide with AuPd/Fe-MOF, thereby enhancing the aptasensor's sensitivity. Moreover, the dual HP design effectively reduces the likelihood of non-specific capture and minimizes false positives. In this study, various analytical techniques were utilized to characterize the material and evaluate the aptasensor's performance. The morphological characteristics of the material were observed using scanning electron microscopy (SEM). Energy-dispersive spectroscopy (EDS) and X-ray diffraction (XRD) were employed to analyze the elemental composition and distribution of the material, respectively. The electrochemical behavior of the sensor was studied using cyclic voltammetry (CV), while electrochemical impedance spectroscopy (EIS) helped understand the aptasensor's assembly process. Furthermore, the aptasensor's performance was assessed using differential pulse voltammetry (DPV). Under the optimized experimental conditions, the constructed sensor demonstrated effective detection of Cd 2+ in the concentration range of 10 –4 –10 µM, with a remarkably low detection limit of 2.27 × 10 –5 µM. The feasibility of the sensor was validated by successfully detecting Cd 2+ in real water samples. .
研究领域:
分析化学
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环境科学
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材料科学
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电化学
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产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2018
·
IF 2.746
Bin Zhou,Xin-Yi Yang,Yong-Sheng Wang,Jie-Can Yi,Zhen Zeng,Huan Zhang,Ya-Ting Chen,Xi-Jiang Hu,Qing-Li Suo
A label-free fluorescence aptasensor based on conformational switching of aptamer induced by Cd 2+ was established for the good selective determination of Cd 2+ . The aptamer could act as a recognition element for Cd 2+ . SYBR green I (SG), as a signal reporter, can bind to the small groove of double-stranded DNA (dsDNA) constituted the aptamer and the complementary strand, establishing the dsDNA-SG complex and generating high fluorescence intensity . In the presence of Cd 2+ , the specific recognition and binging of aptamers preferentially with Cd 2+ induce free of complementary strands from dsDNA and conformational switching of aptamer from dsDNA to a stem-loop structure, fluorescence intensity of system decrease dramatically. Under the optimum experiment parameters, the aptasensor shows a good linear range from 1.12 μg L −1 to 224.82 μg L −1 and the excellent detection limit as low as 0.34 μg L −1 . The relative standard deviations (RSD) for determination of Cd 2+ (n = 8) were lower than 4%, and the recoveries were in the range of 98.57% ~ 102.49%. The use of fluorescence aptasensor has good selectivity and does not require any sample treatment or target preconcentration for the detection of Cd 2+ in real samples.
研究领域:
分析化学
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环境科学
·
生物化学
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产品关联
DOI
高影响因子
Nanoscale
·
2020
·Vol. 13
·期 2
·1283-1290
·
IF 6.895
Chang Liu,Yuxin Luo,Huijie Wen,Yanxia Qi,Guoyue Shi,Jingjing Deng,Tianshu Zhou
Herein, combined with a pervasive smartphone installed with a color recognition app, dual-responsive CDs@Eu/GMP ICPs were designed as a red-to-blue paper-based colorimetric sensor for the point-of-use analysis of cerebral acetylcholinesterase (AChE) upon Cd2+ exposure. Blue-emitting CDs with multi-functional groups as guests were encapsulated into the network of Eu/GMP ICPs to obtain CDs@Eu/GMP ICPs with the sensitized red fluorescence of Eu3+. With the presence of thiocholine (TCh), derived from acetylthiocholine (ATCh) hydrolyzed by AChE, the coordination environment of the CDs@Eu/GMP ICPs was interrupted, leading to the collapse of the CDs@Eu/GMP ICP network and the corresponding release of guest CDs into the surrounding environment. Consequently, the sensitized red fluorescence of Eu3+ decreased and the blue fluorescence of the CDs increased. This obvious red-to-blue fluorescent color changes of CDs@Eu/GMP ICPs on test paper could then be integrated with the smartphone for point-of-use analysis of cerebral AChE upon Cd2+ exposure, which not only offers a new analytical platform for a better understanding of the environmental risk of Alzheimer's Dementia (AD), but also holds great potential in the early diagnosis of AD even at the asymptomatic stage with the decrease in CSF AChE as an early biomarker.
研究领域:
分析化学
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环境科学
·
神经科学
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材料科学
·
生物医学工程
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产品关联
DOI
PubMed
高影响因子
SENSORS
·
2020
·Vol. 20
·期 4
·995
·
IF 3.275
Lina Chen,Yue Lu,Minshu Qin,Fa Liu,Liang Huang,Jing Wang,Hui Xu,Na Li,Guobao Huang,Zhihui Luo,Baodong Zheng
In this work, we have fabricated a novel difunctional magnetic fluorescent nanohybrid (DMFN) for the determination of cadmium ions (Cd2+) in water samples, where the “off-on” model and “ion-imprinting” technique were incorporated simultaneously. The DMFN were composed of CdTe/CdS core-shell quantum dots (QD) covalently linked onto the surface of polystyrene magnetic microspheres (PMM) and characterized using ultraviolet-visible spectroscopy (UV-Vis), fluorescence spectroscopy, and transmission electron microscopy (TEM). Based on the favorable magnetic and fluorescent properties of the DMFN, the chemical etching of ethylene diamine tetraacetic acid (EDTA) at the surface produced specific Cd2+recognition sites and quenched the red fluorescence of outer CdTe/CdS QD. Under optimal determination conditions, such as EDTA concentration, pH, and interfering ions, the working curve of determining Cd2+was obtained; the equation was obtained Y = 34,759X + 254,894 (R= 0.9863) with a line range 0.05–8 μM, and the detection limit was 0.01 μM. Results showed that synthesized magnetic fluorescent microspheres had high sensitivity, selectivity, and reusability in detection. Moreover, they have significant potential value in fields such as biomedicine, analytical chemistry, ion detection, and fluorescence labeling.Keywords:bifunctional;magnetic;fluorescent;Cd2+;detection;ion-imprinting
研究领域:
分析化学
·
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
VACUUM
·
2025
·
IF 3.9
Qingdan Liao,Dahua Yu,Xitong Li,Jingxin Huang
Hydrothermal carbon (HC) demonstrates significant potential in heavy metal removal due to its low production cost and high adsorption efficiency. However, the impact of drying methods on HC performance is often overlooked. This study employed six types of agricultural waste as precursors to prepare HC using four different drying methods and evaluated their performance through Cd 2+ adsorption experiments. Compared to natural drying, vacuum high temperature oven drying significantly increased the C-O functional group content by 25.29 %, optimized the pore structure, thereby enhancing the specific surface area and promoting mass transfer, diffusion, and adsorption behavior. In contrast, high temperature oven drying had a lesser degree of damage to the pore structure, while vacuum freeze drying led to the collapse of pores due to mechanical forces during ice crystal formation and sublimation, reducing the specific surface area to 2.15 m 2 /g. Additionally, the study comprehensively investigated other mechanisms such as complexation, co-precipitation, kinetics, and theoretical calculations. The practicality of this HC was assessed through seven cycles of adsorption-desorption. This study provides important scientific basis for the application of hydrothermal carbon in heavy metal removal, emphasizes the key role of drying methods, and points to a more energy-saving and environmentally friendly realization path.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）