JOURNAL OF HAZARDOUS MATERIALS
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2022
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IF 14.224
Muhammad Zaheer Afzal,Peng Zu,Chun-Miao Zhang,Jing Guan,Chao Song,Xue-Fei Sun,Shu-Guang Wang
Pharmaceuticals are necessary to be removed from environment. Herein TiO 2 incorporated biochar made from pyrolysis of agricultural wastes was encapsulated into chitosan to obtain a novel hydrogel beads. This hydrogel beads executed a dual role as both adsorbent and sonocatalyst, which proved to be suitable for the removal of antibiotic ciprofloxacin (CIP) from water. The results showed that adsorption of CIP followed pseudo first order kinetics model and Langmuir adsorption isotherm model, having maximum adsorption at pH 9. Whereas the degradation was more efficient at pH 6 due to greater standard potential for • OH/H 2 O in acidic media. The degradation was maximum at 150 W of ultrasonic power, then decreased in presence of dissimilar electrolytes and even reduced to 0 in presence of Na 3 PO 4 . Different quenchers such as benzoquinone (BQ), Triethanolamine (TEA) and isopropyl alcohol (IPA) reduced degradation efficiency (DE) and mineralization efficiency (ME). The DE was decreased from 85.23% to 81.50% (BQ), 74.27% (TEA), and 61.77% (IPA) within 25 min. The prepared sonocatalyst was capable of regeneration with DE, remaining sufficiently high (62%) even after four regeneration steps. These results indicate that titanium-biochar/chitosan hydrogel beads (TBCB) are durable and effective for long-term CIP removal.
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Environmental Science-Nano
·
2021
·Vol. 9
·期 1
·349-360
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IF 8.131
Cailiang Yue,Changqing Zhu,Wenting Zheng,Jinli Qiu,Zhiling Du,Chen Ling,Fu-Qiang Liu
Highly efficient mineralization of refractory organic pollutants is an admittedly difficult problem for most photocatalytic processes. Herein, a hierarchical type-II heterojunction Bi2MoO6/Bi/BiOBr-x (BMO/Bi/BOB-x) was successfully fabricated via a one-pot solvothermal method. The optimal BMO/Bi/BOB-2 exhibited an ∼80% mineralization ratio of ciprofloxacin under simulated solar irradiation, outperforming most reported photocatalysts. ˙OH was demonstrated to be the dominant reactive species. The ˙OH production capacity of BMO/Bi/BOB-2 increased by 76.2% compared with that of BMO/BOB, highlighting the key role of Bi nanoparticles (Bi NPs). Bi NPs not only induced a strong localized surface plasmon resonance effect to enhance the utilization of visible light, but also acted as an electron mediator to accelerate the separation of e−/h+ pairs. Due to the specific redox potential, the separated h+ and e− could activate H2O and O2 to produce ˙OH synchronously. Overall, this work provided a valuable strategy to design a plasmonic Bi NP-enhanced type-II heterojunction for the efficient treatment of refractory organic wastewater.
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Materials Today Communications
·
2021
·
IF 3.383
Ruizhe Lian,Jinxing Cao,Xiaohong Jiang,Aleksandr V. Rogachev
Chitosan/gelatin/poly (vinyl alcohol) (CS/Gel/PVA) composite films prepared by the tape-casting, with ciprofloxacin hydrochloride (CIP) as model drug incorporated, can prolong the drug release cycle. The results show that the diameter of CS/Gel/PVA/CIP composite films against Staphylococcus aureus could reach 15 mm after 30 days of sustained release in phosphate buffered solution. Moreover, the CIP release is divided into the rapid release stage and slow-release stage, which achieves rapid sterilization and long-term antibacterial effect. The results show that after 30 days of immersion in PBS, the CIP cumulative release concentration from CS/Gel/PVA/CIP composite films is 13.53 μg/mL, and the CIP cumulative release concentration reaches 87.8 % of the total release on the 3th day of immersion. Meanwhile, the thermal stability and mechanical properties of CS/Gel/PVA/CIP composite film can be improved when the CIP is added into CS/Gel/PVA composite films. Besides, the cell viability of CS/Gel/PVA/CIP composite films reaches 90.85 ± 5.50 % ( p < 0.05) after co-culture with MC3T3-E1 cells for 48 h, which proves that CS/Gel/PVA/CIP composite films have good cytocompatibility and biosecurity.
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SCIENCE OF THE TOTAL ENVIRONMENT
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2020
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IF 6.551
Mihebai Yilimulati,Longfei Wang,Xiaoli Ma,Chuanwang Yang,Nuzahat Habibul
Plastic debris is ubiquitous in aquatic systems and has been proven vehicles for the transport of various pollutants including trace organic compounds. Nanoplastics have large specific surface area and hydrophobic characteristics and therefore are capable of adsorbing other organic or inorganic chemicals from the environment. Antibiotics, as another class of emerging contaminants , have raised significant research concern in recent years as they pose threats to the ecosytems and human health. Nevertheless, little information is available on the adsorption behaviors of antibiotics onto nano-sized plastics. The toxicity of combined nanoplastics and antibiotics is also largely unknown. In this study, the physicochemical and thermodynamic interactions between representative nanoplastics, which containing a carboxyl functional group of polystyrene nanoplastics (PS-COOH), and typical antibiotic, i.e., ciprofloxacin (CIP) were investigated in a batch adsorption experiment. The specific thermodynamic correlation function of PS-COOH combined with CIP was obtained through isothermal titration microcalorimetry (ITC) analysis. The adsorption kinetics and isotherm of CIP on PS-COOH closely fit the pseudo-second-order kinetic model ( r 2 = 0.99) and Freundlich isotherm ( r 2 = 0.99). The ITC results showed that the adsorption reaction of PS-COOH with CIP was a spontaneous exothermic reaction . The adsorption of antibiotics on nanoplastics may aggravate the negative impacts of these two pollutants on aqueous ecosystems, and we hypothesized that would be reflected in the survival rate of model organism of Caenorhabditis elegans when exposed to this combination. This work used a mechanistic approach to unravel the adsorption behavior of antibiotics on nanoplastics and shed light on their potential impact on aquatic ecosystems .
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Journal of Environmental Sciences
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2020
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IF 4.302
Yonghao Wang,Wenqi Wei,Yuzhi Lin,Mian Zhang,Yongjing Wang,Minghua Liu
In this work, magnesium silicate-based sulfonated polystyrene sphere composites (SPS/MgSi) were synthesized by one-step (SMD1) and two-step (SMD2) methods. For SMD1, MgSi particles were densely assembled on the surface of SPS, assisted by complexation between Fe 3+ and hydroxyl phenol. For SMD2, SPS/SiO 2 was firstly obtained by the same method as SMD1, and then SPS/SiO 2 was transformed directly to SPS/MgSi under hydrothermal conditions. Therefore, MgSi obtained by the two-step method had an interwoven structure. Compared to SPS, MgSi and SMD1, SMD2 presented a larger specific surface area and more negative surface charges. Therefore, SMD2 showed superior adsorption performance toward CIP with concentrations of 5, 10 and 50 mg/L, and for 50 mg/L, the equilibrium adsorption capacity could reach 329.7 mg/g. The adsorption process is fast and can be described by the pseudo-second-order kinetic model. The relationship between pH value and Zeta potential demonstrated that electrostatic interaction dominated the adsorption process. In addition, competitive adsorption showed that the effect of Na + was negligible but the effect of Ca 2+ was dependent on its concentration. Humid acid (HA) could slightly promote the absorption of CIP by SMD2. After five rounds of adsorption-desorption, the equilibrium adsorption capacity of SMD2 still remained at 288.6 mg/L for 50 mg/L CIP. Notably, SMD2 presented likewise superior adsorption capacity for CIP with concentrations of 10 and 50 mg/L in Minjiang source water. All the results indicated that this synthesis method is universal and that SMD2 has potential as an adsorbent for CIP removal from aquatic environments.
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2023
·Vol. 30
·期 37
·87830-87850
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IF 5.8
Liu Gen,Lin Yingzi,Li Siwen,Shi Chunyan,Zhang Dongyan,Chen Lei
Fe-BOC-X
photocatalyst was successfully prepared by solvothermal method. The photocatalytic activity of Fe-BOC-X was determined by ciprofloxacin (CIP), a typical fluoroquinolone antibiotic. Under sunlight irradiation, all Fe-BOC-X showed better CIP removal performance than original BiOCl. In comparison, the photocatalyst with iron content of 50 wt% (Fe-BOC-3) has excellent structural stability and the best adsorption photodegradation efficiency. The removal rate of CIP (10 mg/L) by Fe-BOC-3 (0.6 g/L) reached 81.4% within 90 min. At the same time, the effects of photocatalyst dosage, pH, persulfate, persulfate concentration, and combinations of different systems (PS, Fe-BOC-3, Vis/PS, Vis/Fe-BOC-3, Fe-BOC-3/PS, and Vis/Fe-BOC-3/PS) on the reaction were systematically discussed. In reactive species trapping experiments, electron spin resonance (ESR) signals revealed that the photogenerated holes (h + ), hydroxyl radical (•OH), sulfate radical (•SO 4 − ), and superoxide radical (•O 2 − ) played an important role in CIP degradation; hydroxyl radicals (•OH) and sulfate radicals (•SO 4 − ) play a major role. Various characterization methods have demonstrated that Fe-BOC-X has larger specific surface area and pore volume than original BiOCl. UV–vis DRS indicate that Fe-BOC-X has wider visible light absorption and faster photocarrier transfer and provides abundant surface oxygen absorption sites for effective molecular oxygen activation. Accordingly, a large number of active species were produced and participated in the photocatalytic process, thus effectively promoting the degradation of ciprofloxacin. Based on HPLC–MS analysis, two possible decomposition pathways of CIP were finally proposed. The main degradation pathways of CIP are mainly due to the high electron density of piperazine ring in CIP molecule, which is mainly attacked by various free radicals. The main reactions include piperazine ring opening, decarbonylation, decarboxylation, and fluorine substitution. This study can better open up a new way for the design of visible light driven photocatalyst and provide more ideas for the removal of CIP in water environment.
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CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
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2023
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IF 1.2
Xiaoxiao LU,Jingchan ZHAO
The biochar (FS-PNBC) is prepared by pyrolyzing mixed biomass of fish scale and pine needle in varied proportions in a tube furnace. The biochar was characterized by a specific Brunauer-Emmett-Teller (BET) surface area analyzer, scanning electron microscope (SEM), Fourier infrared spectrometer (FTIR), and X-ray diffractometer (XRD). In a solution with an initial concentration of 60 mg/L, the adsorption of ciprofloxacin (CIP) by a 1:1 ratio of fish scale and pine needle co-pyrolyzed biochar (FS-PNBC1) reached 27.97 mg/g. The adsorption properties such as thermodynamics, kinetics, isothermal adsorption, and adsorption factors were investigated by batch experiments. The results indicate that FS-PNBC exhibits a significantly large specific surface area, abundant pore structure, and a high level of porosity. After approximately 180 min, adsorption equilibration was achieved in a pH=4 solution. The kinetic data was well-matched with a quasi-second-order model, suggesting that chemisorption plays a role in the adsorption process. Isothermal adsorption and thermodynamic results indicate that the adsorption of CIP by biochar is more consistent with the Freundlich model, which suggests multilayered non-homogeneous phase adsorption and an exothermic entropy-increasing reaction capable of proceeding spontaneously. FS-PNBC contains oxygen-containing functional groups, and through FTIR analysis, it was observed that hydrogen bonding, π-π bonding, and electrostatic interaction are closely linked to adsorption. This study demonstrates that biochar produced through the co-pyrolysis of fish scale and pine needle has the potential to serve as an efficacious adsorbent for extracting ciprofloxacin from wastewater.
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Frontiers in Microbiology
·
2023
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IF 5.2
Zhao-xia Luo,Yuting Li,Mei-fang Liu,Rui Zhao
Staphylococcus aureus readily forms biofilms on host tissues and medical devices, enabling its persistence in chronic infections and resistance to antibiotic therapy. The accessory gene regulator (Agr) quorum sensing system plays a key role in regulating S. aureus biofilm formation. This study reveals the widely used fluoroquinolone antibiotic, ciprofloxacin, strongly stimulates biofilm formation in methicillin-resistant S. aureus , methicillin-sensitive S. aureus , and clinical isolates with diverse genetic backgrounds. Crystal violet staining indicated that ciprofloxacin induced a remarkable 12.46- to 15.19-fold increase in biofilm biomass. Confocal laser scanning microscopy revealed that ciprofloxacin induced denser biofilms. Phenotypic assays suggest that ciprofloxacin may enhance polysaccharide intercellular adhesin production, inhibit autolysis, and reduce proteolysis during the biofilm development, thus promoting initial adhesion and enhancing biofilm stability. Mechanistically, ciprofloxacin significantly alters the expression of various biofilm-related genes ( icaA , icaD , fnbA , fnbB , eap , emp ) and regulators ( agrA , saeR ). Gene knockout experiments revealed that deletion of agrC , rather than saeRS , abolishes the ciprofloxacin-induced enhancement of biofilm formation, underscoring the key role of agrC . Thermal shift assays showed ciprofloxacin binds purified AgrC protein, thereby inhibiting the Agr system. Molecular docking results further support the potential interaction between ciprofloxacin and AgrC. In summary, subinhibitory concentrations of ciprofloxacin stimulate S. aureus biofilm formation via an agrC -dependent pathway. This inductive effect may facilitate local infection establishment and bacterial persistence, ultimately leading to therapeutic failure.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2023
·
IF 5.2
Dan Yang,Meng Du,Zia-ud Din,Shikui Yang,Lei Chen,Jie Cai,Jie Pang,Xi Chen,Wenping Ding
The Gum Ghatti (GG)/Konjac Glucomannan (KGM)/zeolitic imidazolate framework-8 (ZIF-8) composite aerogels (GKZ) were synthesized by the sol-gel method and the vacuum freeze-drying method for effective removal of ciprofloxacin (CIP) from contaminated water. The results showed that the addition of different concentrations (0, 0.4, 0.6, 0.8 wt%) of GG could promote homogeneity but weakened the molecular interaction of the aerogel system without water. Remarkably, the ZIF-8 maintained the crystal structure, as well as its dispersion on the surface of aerogel, was significantly improved. Additionally, it was also found that the incorporation of moderate GG was favored regarding CIP adsorption, and GKZ with 0.6 % GG (GKZ0.6) exhibited the highest adsorption capability for CIP around 1035.4 mg/g. Besides, the effects of various ions, ionic strength , and pH on CIP adsorption were also investigated, which provided the reference for guiding the utilization of GKZ0.6. Furthermore, at fewer cycles, the adsorption efficiency of GKZ0.6 on CIP showed less loss. These features revealed that the GKZ composite aerogels might be a promising adsorbent for CIP removal from water.
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Environmental Science-Nano
·
2018
·Vol. 5
·期 12
·2876-2887
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IF 6.087
Wei Ma,Binghua Yao,Wen Zhang,Yangqing He,Yan Yu,Jinfen Niu,Cheng Wang
Multi-flaw MoS2 nanosheets were synthesized by a hydrothermal method by controlling the molar ratio of Mo and S. The physical and chemical properties and structures of the samples were characterized by SEM, TEM, N2 adsorption/desorption isotherms, XRD, Raman spectroscopy, and XPS. The construction of flaws with abundant exposed edges in the ultrathin MoS2 nanosheets played an important role in improving the piezocatalytic performance for the degradation of antibiotic ciprofloxacin (CIP) by forming the active sites. Compared with flaw-free MoS2, multi-flaw MoS2 nanosheets had a high number of atomic layers (abundant odd numbers of atomic layers) and exhibited excellent adsorption-piezocatalytic ability, decomposing 99% of CIP in 30 s under ultrasonic irradiation. Furthermore, the total organic carbon (TOC) analysis indicated that 56% of CIP was completely mineralized after 5 min of ultrasonic irradiation. The eradication mechanism of CIP followed pseudo-second-order kinetics with a maximum degradation rate constant of 1.29 L mg−1 s−1. The superior piezocatalytic performance of multi-flaw MoS2 nanosheets was mainly attributed to the highly efficient separation of electron–hole pairs caused by the strain-induced piezoelectric field (an internal electric field). Active species trapping and terephthalic acid (TA) fluorescence experiments demonstrated that the hydroxyl radicals (˙OH) were the major reactive oxygen species that degraded CIP. In addition, UPLC-MS analysis was used for monitoring the intermediates in CIP decomposition. The complete opening of the piperazine and quinolinic rings and the formation of simpler aliphatic compounds were observed. A possible degradation pathway was proposed based on the UPLC-MS data. The ultrafast degradation efficiency of multi-flaw MoS2 nanosheets could be used for practical environmental remediation applications.
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ENVIRONMENTAL POLLUTION
·
2019
·
IF 5.714
Rong Shen,Yichang Yu,Rong Lan,Ran Yu,Ze Yuan,Zhining Xia
As a new type of pollutant, fluoroquinolones (FQs) antibiotics are ubiquitous in environment and have some threat to human health and ecological environment. Their ecological toxicity to the environment urgently need to be assessed. Therefore, we firstly explored the toxic effects and possible mechanism of cardiovascular toxicity induced by gatifloxacin (GTFX) and ciprofloxacin (CPFX) using zebrafish model. After 24 h exposure, the zebrafish treated with GTFX showed pericardial edema which was further investigated by histopathological examination, while CPFX exposure did not induce morphological abnormalities. However, both of them induced cardiac dysfunction, such as decreased heart rate and cardiac output which was showed a positive correlation with the concentration. To better understand the possible molecular mechanisms underlying cardiovascular toxicity in zebrafish, we investigated the transcriptional level of genes related to calcium signaling pathway and cardiac muscle contraction . The results indicated that the expression of ATPase ( atp2a1l ) and cardiac troponin C ( tnnc1a ) genes were significantly inhibited, the expression of calcium channel ( cacna1ab ) gene showed slight promoted trend after CPFX exposure. For zebrafish treated with GTFX, the expression of atp2a1l genes was also significantly inhibited, while the expression of tnnc1a genes was slightly inhibited and cacna1ab genes expression had no obvious effect. The present study firstly revealed that GTFX exposure can induce morphological and functional abnormalities on the cardiovascular system of zebrafish. Though CPFX exposure did not induce morphological abnormalities, the function of cardiovascular system was still damaged. Mechanistically, this toxicity might result from the pressure of down-regulation of genes associated with calcium signaling pathway and cardiac muscle contraction. The results of this study can provide a valuable theoretical basis for the establishment of FQs environmental quality standards in water environment, environmental drug regulation and risk management.
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ENVIRONMENTAL TECHNOLOGY
·
2012
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IF 1.406
Xiaojie Zhang,Xiaoyan Gao,Pengwei Huo,Yongsheng Yan
Molecularly imprinted polymers (MIPs) for selective removal of ciprofloxacin (CIP) was prepared by a surface imprinting technique. The MIPs was characterized by Fourier transform infrared spectroscopy and scanning electron microscopy (SEM). The selectivity of the sorbent was investigated by a batch competitive binding experiment using aqueous CIP and gatifloxacin, CIP and chloramphenicol, and CIP and tetracycline mixtures, respectively. The static uptake capacity and selectivity coefficient of the MIPs are higher than those of the non-imprinted sorbent. The imprinted functionalized sorbent offered a fast kinetics for the extraction of CIP, which was obtained within 12 min. In a test of five extraction cycles, the adsorption capacity of the sorbent was above 92% of that of the fresh sorbent. Experimental results showed the potential of MIPs for selectivity removal of CIP.
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