CHEMICAL ENGINEERING JOURNAL
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2025
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IF 13.2
Long Yang,Wenbo Hu,Ruida Cao,Qingqing Zhou,Chencheng Hu,Biao Dong,Hongwei Song,Lin Xu
All-nanofiber triboelectric nanogenerators (TENGs) have emerged as promising candidates for wearable electronics and IoT systems due to their intrinsic flexibility, breathability, and skin-conformable designs. Yet, the trade-off between dielectric enhancement and mechanical reliability persists in current commonly-used composite strategies. In this study, we present a novel liquid metal (LM) inner-encapsulated all-nanofiber TENG (TM-TENG) to improve both mechanical energy harvesting and self-powered sensing capabilities. By embedding LM nanoparticles into a hierarchically structured nanofiber network, a dual optimization of interfacial polarization and charge trapping capabilities is achieved. The resulting LM-TENG demonstrates excellent electrical outputs, with open-circuit voltage of 162 V , short-circuit current of 3.3 μA, and power density of 176 mW∙m −2 as well as ultralong-term stability (>10,000 cycles). Its pressure-sensitive triboelectric response (6.11 V ∙kPa −1 ) enables multimodal sensing, including real-time physiological signal monitoring, gait analysis, information transmission, and encrypted human-machine communication. Remarkably, the LM-TENG device can also serve as an impedance-matched and sustainable power source for wireless humidity sensors. When integrated with a convolutional neural network, the integrated system achieves 96.97 % accuracy in sleep apnea severity classification. This work establishes a universal strategy for designing high-performance, fully fiber-based TENGs, which is promising for next-generation smart healthcare systems and human-machine interfaces.
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Small
·
2025
·
IF 12.1
Jiahao Zhang,Hongwang Tang,Hucheng Wang,Peiwen Cai,Yuliang Gao,Xuhong Guo,Yiming Wang,Fu-Zhen Xuan
Access to multifunction-integrated hydrogel microrobots is highly desired in many complex application scenarios, yet remains a challenging task. Here, adaptive out-of-equilibrium hydrogel microrobots exhibiting autonomous deformation, controllable autolysis, and directed locomotion in response to orchestrated chemical and physical signals are reported. These hydrogel microrobots are prepared by crosslinking carboxyl-decorated polymers through coumarin dimerization. Upon the addition of carbodiimide as a chemical fuel, the hydrophilic carboxyl groups are converted to hydrophobic anhydrides, leading to shrinking of the microrobots. However, with the depletion of fuel, the formed anhydrides spontaneously hydrolyze to the initial carboxyl groups, thus resulting in an autonomous swelling of the microrobots to their original size. Moreover, because of the efficient photocleavage of coumarin dimers, the microrobots can rapidly disintegrate (<10 min) upon irradiation. With the incorporation of magnetic powders, these hydrogel microrobots can be guided to move in space by a magnetic field. By virtue of these seamlessly integrated functions, the hydrogel microrobots can be manipulated to adaptively move through a narrow terrain and release the loaded cargo at a target position. This work may boost the development of multifunction-integrated lifelike soft robots for many complicated applications ranging from precision drug delivery to non-invasive therapies.
研究领域:
材料科学
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生物医学工程
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软体机器人
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SEPARATION AND PURIFICATION TECHNOLOGY
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2025
·
IF 9
Xingrui Tang,Qiang Xian,Shibing Zuo,Yiyang Zeng,Hao Li,Jun Wen
Seawater uranium extraction via adsorption technology can effectively alleviate the shortage of terrestrial uranium resources and ensure a steady, sustainable supply of essential uranium. Most uranium adsorbents face challenges like inefficient ion transport, salt shrinkage and marine biofouling. Thus, we innovatively constructed zwitterionic marine-adaptive porous cryogel adsorbents (PAO-SBMA) for uranium extraction from seawater. The incorporation of zwitterionic sulfobetaine methacrylate (SBMA) not only regulates the hierarchical pore architecture of porous adsorbents but also imparts superhydrophilicity, antifouling capability, and salt-shrinkage resistance. Additionally, density functional theory (DFT) calculations, FT-IR and XPS spectra jointly prove that the sulfonic acid groups perform as effective synergistic coordinating groups, and facilitate the efficient adsorption of uranium by amidoxime-based adsorbents. Through this “triple enhancement” strategy, the PAO-SBMA-1.5 (m AN /m SBMA = 1.5) exhibits remarkable uranium adsorption performance. Its adsorption capacity is approximately three times that of the polyamidoxime (PAO), reaching 1595.90 mg/g. After 21 days of test in natural seawater, PAO-SBMA-1.5 demonstrates a high uranium extraction capacity of 13.88 mg/g, and its extraction efficiency has reached as high as 84 %. The zwitterion-based adsorbent is poised to become a promising candidate for implementation in marine uranium extraction operations.
研究领域:
环境科学
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材料化学
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核能
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海洋资源利用
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吸附技术
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高影响因子
Journal of Inflammation Research
·
2025
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IF 4.1
Siyue Bo,Xiaotong Wang,Jiani Qian,Guoqiang Ma,Zheng Ying,Duanmin Hu,Chunyan Hou,Junfeng Ma,Longjiang Xu,Shuang Yang
Background Ulcerative colitis (UC) disrupts the colon’s protective mucus layer, exposing the epithelium to bacteria and triggering inflammation. This barrier, crucial for intestinal health, depends on complex glycosylation, notably sialic acid modifications. However, the precise role of sialic acid acetylation and the enzyme SIAE (sialic acid acetylesterase) in UC pathogenesis remains unclear. This study investigates the role of glycosylation changes, specifically sialic acid de-acetylation, in UC progression.Methods Tissue samples were obtained from patients with ulcerative colitis (UC) and colorectal cancer at the Second Affiliated Hospital of Soochow University. HT-29 cells were utilized to investigate the molecular mechanisms of SIAE in UC pathogenesis. Mass spectrometry was performed to analyze differences in protein and glycoprotein expression. Western blot (WB) and immunohistochemistry (IHC) were used to examine SIAE protein expression changes during inflammation. Furthermore, polymerase chain reaction (PCR) and immunofluorescence were employed to determine the effects of SIAE on sialic acid levels and mucosal immunity.Results In this study, we characterized proteins and glycoproteins from patient tissues with UC, finding that sialic acid acetylesterase (SIAE) is upregulated in UC. HT-29 cells exposed to TNF-α induced an inflammatory response with a 5-fold increased expression of SIAE and NEU1 when TNF-α was at a concentration of 100 ng/mL. Mass spectrometry analysis revealed a reduction in acetylation on glycans and glycoproteins, while confocal microscopy confirmed a decrease in sialic acid on the cell surface. Gene expression analysis showed that CDH1, CTNND1, and ITGA8 were significantly downregulated in HT-29 cells stimulated by TNF-α, suggesting a reduction in cell-cell adhesion. SNA lectin-confocal microscopy revealed a reduction of sialic acid on HT-29 cells in TNF-α-induced UC cell models.Conclusion This study demonstrates that SIAE is significantly upregulated in ulcerative colitis (UC) tissues and TNF-α-stimulated HT-29 cells, leading to a marked reduction in sialic acid acetylation and cell surface sialic acid levels. These changes correlate with decreased expression of cell adhesion molecules, suggesting a disruption of the mucosal barrier integrity. Consequently, SIAE-mediated sialic acid de-acetylation emerges as a critical factor in UC pathogenesis, potentially serving as both a valuable biomarker and a promising therapeutic target.
研究领域:
医学
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分子生物学
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免疫学
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PubMed
高影响因子
MRS Advances
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2025
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IF 0.9
Wang Xiaodong,Yu Xinrun,Xu Yushan,Yu Juan,Huang Pei
A series of PI aerogel composite films were prepared through adjustments made to the ratio of dianhydride and chemical imidization reagents, the crosslinker content, and the utilization of a non-solvent induced phase separation process. The prepared PI aerogel films exhibited a minimum dielectric constant of 1.39 (10 6 Hz), a maximum water contact angle of 137.8°, and demonstrated excellent recyclability. Furthermore, the prepared polyimide aerogel films demonstrated exceptional thermally stable characteristics, with Td 5% maintained at approximately 510 °C, Tg values remaining above 230 °C, and a low coefficient of thermal expansion, at 55.8 ppm/K. The prepared PI aerogel films exhibit a high degree of porosity (74.1%), a relatively low density (0.392 g/cm 3 ), and considerable tensile strength (up to 6.2 MPa). It has been demonstrated that these polyimide aerogel films are highly promising for the construction of high-frequency microelectronic devices. Graphical abstract
研究领域:
材料科学
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高分子科学
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纳米技术
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电子工程
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化学工程
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CHEMISTRY & BIODIVERSITY
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2026
·Vol. 23
·期 1
·e02728
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IF 2.5
Ziqiang Zhao,Yanqun Huang,Hongyun Lan,Daozhan Huang,Rimei Chen,Libing Xu,Zhenfang Li,Zhiqing Ning,Yu Feng
To increase solubility, amines, including dimethylamine (DMA) and isopropylamine, are included in commercial formulations of phenoxyacetic acid herbicides, such as 2,4-dichlorophenoxyacetic acid (2,4-D) and 2-methyl-4-chlorophenoxyacetic acid (MCPA), but amine volatilization during production and use poses challenges for the social environment and living organisms. To mitigate the problem by replacing currently applied volatilized amines and developing high-efficacy and environment-friendly herbicides, three camphene-derived ammonium phenoxyacetates and one glyphosate were synthesized and characterized. The preliminary herbicidal activity tests showed that several compounds displayed higher herbicidal performance against Lolium multiflorum Lam. and Brassica campestris than their corresponding herbicide-amine salts. Compared to DMA salts of 2,4-D and MCPA, compounds 5b – 5c containing one or two chlorine atoms presented similar or higher herbicidal activity against B. campestris even at a lower concentration (0.0006 mmol/L). Besides, compound 5b with the half maximal inhibitory concentration (IC 50 ) value of 0.000281 mmol/L against B. campestris shoot growth showed 611.7% higher herbicidal activity than that of DMA salt of 2,4-D, whereas compound 5c with an IC 50 value of 0.026 mmol/L against L. multiflorum Lam. shoot growth presented 38.5% higher herbicidal activity than DMA salt of MCPA. This study indicated that compounds 5b – 5c could be promising herbicidal candidates. Graphical To mitigate amine-induced problems and find high-efficacy herbicidal alternatives with low toxicity, four water-soluble camphene-derived ammonium salts were synthesized using camphene-derived primary amine and different commercial herbicides. Most compounds displayed superior herbicidal activity against Lolium multiflorum Lam . and Brassica campestris than their herbicide-amine salts. Particularly, compound 5b with an IC 50 value of 0.000281 mmol/L against Brassica campestris shoot growth showed over 7-fold higher herbicidal activity than 2,4-D dimethylamine salt, indicating its potential for practical application in sustainable agriculture.
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BIOMACROMOLECULES
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2026
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IF 5.4
Ibrahim M. Ammar,Al-Hassan S. Mahdy,Saikat Kumar Panja,Kui Tan,Shanmeng Lin,Quan Gao,Jin Geng
The need for multifunctional polymers in cellular environments arises from their potential applications in cancer treatment, drug delivery, gene delivery, imaging, sensing of different biomolecules, environmental and cellular engineering, etc. However, due to certain limitations, the direct polymerization of multifunctional polymers within cells is not feasible, as it faces many challenges. Therefore, this study emphasizes the synthesis of functionalized molecules outside the cells and subsequent modification of the polymers inside the cells through intracellular postpolymerization modification (iPPM). We investigate Förster resonance energy transfer (FRET) as a technique for confirming the occurrence of postpolymerization reactions in cells in real time without the need for extraction or purification. The FRET reaction consists of 7-nitrobenz-2-oxa-1,3-diazole (NBD) as the FRET donor, integrated as a segment in the polymer backbone, and rhodamine B-polyethylene glycol-dibenzocyclooctyne (RhB-PEG-DBCO) as the FRET acceptor. A copper-free click chemistry method is used as a postpolymerization reaction within cells by the reaction between the azide group on the polymer backbone and DBCO in the FRET acceptor. By employing FRET and a targeted approach, this technique contributes to the development of multifunctional polymers for diverse applications in cellular environments.
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WATER RESEARCH
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2026
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IF 12.4
Hao Li,Xingrui Tang,Qiang Xian,Shibing Zuo,Yiyang Zeng,Chen Xu,Jun Wen
Electrochemical method offers a promising route for the continuous uranium extraction from seawater, thereby holding significant potential to ensure a sustainable supply of uranium for the nuclear energy industry. The electrode material plays a critical role in determining uranium extraction efficiency, demanding excellent mass transfer performance and high selectivity for effective extraction. Herein, inspired by the hierarchically ordered, porous, and intercross-linked vascular bundle structure of lotus petiole, we report the rational design and successful synthesis of zwitterionic ordered porous electrodes (SBMA-MPAO). This biomimetic architecture not only enhances charge/ion transfer rate and ensures sufficient seawater transport, but also provides numerous adsorption sites for uranyl capture. Furthermore, the integration of zwitterionic moieties enables a synergistic interaction with uranyl species, significantly enhancing extraction efficiency. In natural seawater, the SBMA-MPAO electrode achieves an outstanding uranium adsorption capacity of 9.54 mg/g within 72 hours, including a remarkably high uptake rate of 4.58 mg/g/d on the first day, while maintaining excellent selectivity throughout the process. This work proposes a novel strategy to construct high-performance electrodes for uranium extraction from seawater.
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CHEMICAL ENGINEERING JOURNAL
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2025
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IF 13.2
Andrei Popkov,Hao Zhang,Yu Lou,Ziran Su,Jianquan Luo,Manuel Pinelo
Continuous-flow enzyme reactors face major challenges that limit enzymes' industrial use. In case of enzyme membrane reactors (EMRs), the poor performance mainly results from difficulty in achieving high enzyme loading amount, activity recovery, reusability, and unit permeability at the same time. Herein, we propose a novel type of aminated EMR support for fouling-induced enzyme immobilization, obtained by two-step covalent modification of polysulfone (PSF) precursor with polyethyleneimine (PEI) prior to casting by phase inversion. Adding positively charged immobilization sites eliminated the need to reduce pore size for effective enzyme retention - enabling high biocatalytic activity and good mass transport in the same reactor, without compromising each other. The productivity of EMRs with immobilized laccase, carbonic anhydrase (CA), and horseradish peroxidase (HRP) increased by over 1.4-, 6-, and 36-fold, respectively, compared to using commercial PSF and polyethersulfone (PES) supports; showing permeabilities above 2600 LMH.bar −1 and steady continuous operation with minimal enzyme loss (<5 % in total). Considering simplicity and versatility of the method, our findings could expand the potential of immobilized enzymes for a wide range of applications in biosynthesis.
研究领域:
生物催化
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化学工程
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膜技术
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酶工程
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可持续化学
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BIOMACROMOLECULES
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2025
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IF 5.4
Wenyu Zhu,Yiying Ye,Li Zhang,Guangyao Zhao,Jianbo Tan
Polymeric microspheres are indispensable in catalysis, coatings, and biomedical analysis, yet conventional dispersion polymerization requires high stabilizer loadings and often yields surfaces with limited functional accessibility. Here, we report a molecular bottlebrush strategy that overcomes these limitations by employing reversible addition–fragmentation chain transfer (RAFT)-derived macromonomers, followed by ring-opening metathesis polymerization (ROMP) to generate bottlebrush stabilizers for photoinitiated RAFT dispersion polymerization. These bottlebrushes afford robust steric stabilization at significantly reduced loadings and enrich microsphere surfaces with RAFT end groups, enabling facile postpolymerization modification. The resulting PMMA microspheres exhibit exceptional monodispersity, tunable diameters, and versatile surface functionality. Subsequent photoiniferter polymerization yields carboxyl-functionalized microspheres with grafted poly(acrylic acid) chains, providing a high density of accessible carboxyl groups for biomacromolecule conjugation. Optimization of the chain length reveals a critical balance between loading capacity and accessibility, leading to markedly improved performance in bead-based immunoassays. This bottlebrush-mediated approach thus establishes a general and scalable platform for producing size-controlled, surface-functional polymeric microspheres with enhanced bioanalytical utility.
研究领域:
高分子化学
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材料科学
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生物分析化学
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纳米技术
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免疫分析技术
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JOURNAL OF APPLIED POLYMER SCIENCE
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2025
·Vol. 142
·期 41
·e57591
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IF 2.8
Kang Zhu,Yong Li,Yue Jin,Hao Liu,Jun Xiao
In situ polymerized poly(methyl methacrylate) resin, a liquid molding thermoplastic, offers advantages such as low cost, recyclability, and environmental friendliness. However, its poor toughness limits its application potential. This study proposes a toughening method for poly(methyl methacrylate) resin used in liquid molding by copolymerizing it with butyl acrylate (BA) and butyl methacrylate (BMA) monomers. The effects of BA or BMA on the polymerization reaction and mechanical properties were investigated, with a focus on improving toughness. Dynamic thermal analysis (DSC) and 13 C NMR spectroscopy confirmed the formation of copolymers and the incorporation of BA or BMA monomers. The introduction of BA or BMA lowered the glass transition temperature but had minimal impact on the polymerization rate, with only a slight increase in polymerization time (14.77‰ and 4.320‰ for 8% BA or BMA, respectively). Adding small amounts of BA or BMA significantly enhanced the toughness of the resin. When the content reached 4%, elongation at break increased by 103% and 139%, and impact strength improved by 222% and 328%. These results shift the failure mode from brittle to ductile fracture, paving the way for the industrial application of high-performance in situ polymerized poly(methyl methacrylate) resin.
研究领域:
材料科学
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高分子化学
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复合材料
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热塑性树脂
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高分子加工
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2024
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IF 4.9
Junfang Zhang,Zhenming Li,Zhongxu Hao,Haoyang Jiang,Jianguo Tang
Hydrogel sensors for flexible touch-sensing devices have sparked tremendous research interest in wearable electronics for broad applications such as artificial intelligence, information secrecy, and interactive control devices. Although many achievements have been reached in the hydrogel touch-sensing devices, profound challenges remain in the establish of new sensing system and the improvement on the sensitivity to ensure smooth and sensitive touching experience. Herein, a flexible hydrogel sensor as the touchable panel was developed and showed excellent tough-sensing performance for handwriting with high sensitivity. With the flexible and tough hydrogel as the contact layers, the sandwiched hydrogel panel was prepared and showed good touch-sensing performance with high sensitivity (∼500 % ΔI/I 0 , 12.65 N −1 ). This improvement on the sensitivity was ascribed to the increasement of current during the touching process originated from the formation of new circuit branch. Furthermore, it could be used as a portable touchpad for the wearable handwriting. This hydrogel sensor with the high sensitivity for handwriting has great potential in the fields of intelligent screen and wearable electronic device.
研究领域:
材料科学
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生物医学工程
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电子信息
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高影响因子
危险品化学品经营许可证（带存储）