TALANTA
·
2025
·
IF 6.1
Gengli Huang,Shuo Qi,Xiaodong Lu,Faizan Ul Haq,Yuxing Yan,Zhouping Wang
Colorimetric nanosensors based on nanozymes, particularly those utilizing a single absorption peak, often suffer from subtle color variations that challenge accurate visual interpretation and quantification. To overcome this constraint, a multicolor aptasensor by integrating CeO 2 nanozymes with haloperoxidase (HPO)-mimicking activity were developed for ratiometric colorimetric and visual sensing. The CeO 2 nanozymes with exceptional HPO-like activity catalyzes thymol blue iodination to induce dual absorbance peaks changes at 430 nm (decreasing) and 620 nm (increasing), resulting in clear yellow-to-blue color tonality discernible to the naked eye. Crucially, aptamer-regulated enzymatic inhibition is employed, where target binding triggers the release of complementary DNA to modulate the catalytic activity of CeO 2 nanozyme through charge-switchable surface adsorption. The activity-modulated HPO nanozyme induces a remarkable color tonality change from blue to yellow via synergistic modulation of dual absorbance values at 430 nm (increase) and 620 nm (decrease), achieving clear visual distinction. Using kanamycin as a model target, the ratiometric signal (ΔA 620 /A 430 ) demonstrates significantly enhanced sensitivity (>6-fold improvement) compared to single-wavelength detection. The aptasensor further integrates smartphone-based RGB quantification to enable on-site analysis. Validation in milk and honey matrices confirms reliable recoveries (<7 % RSD), indicating their promising practical utility for real-samples detection. This HPO nanozyme platform advances multicolor ratiometric biosensing for on-site food safety monitoring, demonstrating broad applicability in antibiotic residue detection.
研究领域:
生物传感器
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纳米技术
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食品安全监测
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分析化学
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环境检测
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产品关联
DOI
PubMed
高影响因子
MOLECULES
·
2025
·Vol. 30
·期 22
·4399
·
IF 4.6
Yu Luo,Xunxian Chen,Zhen Wan,Yingming Chen
As a cost-effective and environmentally benign photocatalyst, hydrothermal carbonation carbon (HTCC) has been extensively studied in the fields of resource utilization and environmental remediation. In this study, HTCC photocatalysts with efficient photocatalytic performances were prepared from straw using acid modification under hydrothermal conditions. The as-prepared HTCC photocatalysts were applied to the degradation of microcystin-LR and the reduction of aqueous Cr(VI). The critical role of acid modification in the photocatalytic performances of the HTCC photocatalysts was systematically investigated. The results demonstrated that acid-modified photocatalysts exhibited a significantly enhanced removal efficiency for Cr(VI) and microcystin-LR under visible light irradiation. A series of characterization techniques, including Raman spectroscopy and N2adsorption–desorption analysis, revealed that the superior photocatalytic activities of acid-modified HTCC could be attributed to its higher aromatization level, enhanced light-harvesting ability, and increased concentration of active sites compared with pristine HTCC. Furthermore, electron spin resonance (ESR) and trapping experiments indicated that hydrogen radicals (·H) served as the primary active species in the photocatalytic Cr(VI) reduction of straw-based HTCC. This work provides both practical and theoretical insights into the resource utilization of agricultural waste and the remediation of environmental pollution.
研究领域:
环境科学
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材料科学
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光催化
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废弃物资源化利用
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水污染修复
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产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2025
·
IF 8.2
Xiaoli Wei,Mengjun Wang,Mingze Lu,Guancheng Wang,Xiao Wang,Haoan Wu,Yu Zhang
The binding and catalytic sites of natural enzymes play a decisive role in enzymatic processes. Constructing bioinspired catalytic centers and advancing nanozyme-mediated cancer therapeutics represent a significant yet challenging frontier. Herein, we have developed tumor-targeting micellar single-atom nanozymes (Fe(II)NC-SAz-E5 micelles) through a rational design that integrates tumor microenvironment (TME) responsivity and active targeting for synergistic anti-Non-Hodgkin’s lymphoma (NHL) therapy. The Fe(II) ions were precisely anchored into PLGA-PEG-NH2 self-assembled micelle-DOTA-E5 complex via DOTA chelation, forming FeN4(COOH) active sites that mimic natural peroxidase with remarkable catalytic efficiency. Guided by the tumor-targeting peptide E5, these micelles preferentially accumulate in tumor tissues and inhibit metastasis by suppressing the CXCR4/CXCL12 signaling axis. Moreover, tumor cells are effectively eliminated through a self-sustaining cycle of “substrate supply-catalytic amplification-metabolic intervention,” leveraging the elevated levels of H2O2, GSH, and glucose in the TME. Extensive in vitro and in vivo studies demonstrated the micelles’ potent catalytic activity, significant inhibition of lymphoma progression, and strong antimetastatic effects. Notably, the use of FDA-approved PLGA and clinically established DOTA chelation highlights the strong translational potential of this platform for future clinical applications.
研究领域:
纳米医学
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癌症治疗
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生物无机化学
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酶模拟（纳米酶）
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药物递送系统
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生物医学工程
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产品关联
DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2025
·Vol. 14
·期 1
·120662
·
IF 7.2
Bin Ou,Hongwei Rong,Baihui Cui,Jie Zhang,Fang Zhang,Dabin Guo
The coordination calcination method is used to form a coordination complex between Co 2 + and thiophene, which is adsorbed on carbon black (CB) and then calcined to prepare Co-S-C/CB single atom catalyst. Co-S-C/CB could efficiently activate peroxymonosulfate (PMS) by forming Co-S 3 coordination structure and Co-S 3 is the active site for activating PMS. Electron rich region was formed on the Co atom and the Co atom could keep in a low valence state during the catalytic process and donate electrons to PMS to produce radicals (•OH and SO 4 •- ) through a single-electron-reduction. Co-S-C/CB could not only promote PMS to generate •OH and SO 4 •- , but also inhibit the generation of 1 O 2 and O 2 •- . The radical pathway has the lowest Gibbs free energy (ΔG) compared to the 1 O 2 pathway and the Co(IV)=O pathway. Therefore, Co-S-C/CB could regulate the radical pathway of PMS. •OH and SO 4 •- are mainly responsible for the removal of Rhodamine B (RhB). Co-S-C/CB could be applied to efficiently degrade various organic pollutants and has good stability. Macro preparation of Co-S-C/CB could be achieved from both the preparation process and raw material aspects.
研究领域:
环境催化
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高级氧化技术
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材料化学
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纳米催化剂
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水处理
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产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Peng Jin,Niao Fu,Ruining Bai,Qingzhi Liu,Yujiao Liu,Mei Chen,Jieli He
Eutrophication-driven cyanobacterial blooms release microcystin-LR (MC-LR), a potent hepatotoxin, posing severe environmental and public health risks. Effective, safe MC-LR degradation is critical for water remediation. Herein, we propose a rationally designed unique donor–acceptor–acceptor (D-A1-A2) structural strategy to synthesize a covalent organic framework (COF-TFP-TAPT-Me) for visible-light-driven, controllable 1 O₂-mediated MC-LR photocatalysis. Structural/optoelectronic characterization confirmed triazine-based A2 (Melem) incorporation narrowed the parent D-A1 COF's band gap to 1.15 eV (vs. 1.38 eV) and enhanced charge separation via forming continuous π-conjugation, ordered π-π stacking, and a multi-level energy structure that promotes directional electron transfer (1.6-fold higher photocurrent than the parent COF). COF-TFP-TAPT-Me nearly completely degraded MC-LR in 25 min, with a pseudo-first-order rate constant 1.66-fold higher than the parent COF and outperforming benchmarks like P25 and PCN. Mechanistically, its D-A1-A2 configuration effectively enables highly selective and dominant 1 O₂ generation in metal-free COFs (in contrast to mixed ROS in the parent COF) via photosensitized energy transfer, selectively attacking MC-LR's Adda chain (UPLC–MS verified). The catalyst retains >95 % activity after 5 cycles, is stable in natural water, and shows >80 % cell viability in cytotoxicity assays. This work highlights a novel D-A1-A2 framework for regulating 1 O₂-dominated degradation, offering a trinity of high efficiency, stability, and low toxicity strategy for water purification.
研究领域:
环境科学
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材料化学
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光催化
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水处理
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有机框架
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产品关联
DOI
高影响因子
Nature Communications
·
2025
·Vol. 16
·期 1
·10971
·
IF 15.7
Han Yaobao,Han Mengxiao,Wang Tingting,Zhang Hao,Liu Hanghang,Zheng Yanhui,Dong Jun,Li Zhen
Glioblastoma (GBM) is a highly malignant tumor with a high postoperative recurrence rate. It is crucial to develop innovative and effective approaches to prevent its recurrence. Herein, we focus on the important roles of neutrophil extracellular traps (NETs) in the progression of GBM in mice and patients. Neutrophils accumulate around the surgical cavity and release NETs to promote the proliferation and migration of postoperative residual GBM cells. Injection of a hydrogel loaded with copper selenide nanozyme and doxorubicin into the surgical cavity successfully inhibit the formation of NETs and improve the therapeutic efficacy against GBM. 60% of treated GBM mice survive over 24 months, which are 36 times longer than those of untreated mice, and close to the lifespan of healthy mice. The treated mice preserve their essential cognitive functions and basic motor ability. This study demonstrates the great potential of modulating NETs in GBM therapy.
研究领域:
肿瘤学
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免疫学
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纳米医学
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神经外科
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癌症治疗
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产品关联
DOI
PubMed
高影响因子
CHINESE JOURNAL OF STRUCTURAL CHEMISTRY
·
2025
·
IF 10.3
Weixia Wang,Yongji Zhang,Fei Zhao,Libo Wang,Fanpeng Meng,Shuchao Qin,Jinsheng Zhao
Carrier recombination in polymer photocatalysts involves both undissociated exciton decay and charge recombination, which are the main obstacles limiting their photocatalytic activity. Achieving efficient charge generation and separation in a polymer system is a fundamental strategy for the potential success of solar energy conversion to hydrogen, but it remains a huge challenge. In this study, we propose an innovative intermolecular π–π stacking strategy to construct a π-delocalized all-polymer S-scheme heterojunction for photocatalytic hydrogen evolution. Two conjugated porous polymers (CPPs)—PyB, composed of benzo[1,2-b:4,5-b′]dithiophene (BDT) and pyrene units, and PhB, composed of BDT and benzene—were synthesized and integrated with CN nanosheets. The highly planar and π-extended structure of PyB facilitated strong interfacial π–π stacking with CN, forming an extended π-delocalized network that enhanced the internal electric field (IEF), improved charge separation, and boosted visible-light absorption. As a result, the optimized PyB/CN-20 composite achieved a remarkable hydrogen evolution rate (HER) of 23.84 mmol⋅h −1 ⋅g −1 under visible light, approximately 287 times higher than that of pristine CN. This work underscores the critical role of polymer planarity and π-conjugation in heterojunction efficiency, and provides new insights into the rational design of π-delocalized S-scheme systems and establishes a general strategy for developing highly efficient, metal-free photocatalysts by leveraging molecular-level structural control.
研究领域:
材料化学
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光催化
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高分子科学
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能源材料
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纳米材料
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物理化学
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太阳能转换
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产品关联
DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2025
·Vol. 13
·期 6
·120486
·
IF 7.2
Zhao Song,Keren Zhou,Xiaoming Liu,Shuzhao Pei,Wulin Yang,Nanqi Ren,Yidi Chen
Persulfate-based advanced oxidation processes (PS-AOPs) exhibit enhanced oxidant stability and radical persistence compared to traditional H 2 O 2 -AOPs. This study comparatively evaluates redox-active ferrocene (Fc/Fc + ) for activating peroxymonosulfate (PMS) and peroxydisulfate (PDS) toward bisphenol A (BPA) degradation. The Fc/PMS system demonstrates superior BPA removal efficiency and kinetics relative to Fc/PDS, mechanistically attributed to the lower activation barrier for asymmetric PMS (accepting 0.91 e − from Fc) versus symmetric PDS (accepting 0.88 e − from Fc), as quantified by density functional theory (DFT) with Bader charge analysis. Sulfate (SO 4 •− ) and hydroxyl (• OH) radicals were identified as the dominant reactive species in both systems. Crucially, O 2 -mediated Fc-to-Fc + oxidation promotes electrostatic migration of anionic persulfates to the catalyst surface, enhancing activation efficiency. Both systems sustain contaminant removal through Fc + reduction by persulfates, demonstrating regenerative catalytic behavior. For practical application, future work should prioritize catalyst design strategies to accelerate Fc + recycling kinetics and enhance system resilience under oxygen-limited conditions.
研究领域:
环境化学
·
高级氧化技术
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催化
·
水处理
·
理论化学
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产品关联
DOI
高影响因子
Catalysts
·
2025
·Vol. 15
·期 2
·126
·
IF 4
Chi Zhou,Shenglong Jing,Teng Miao,Nianlai Zhou,Hang Zhang,Yi Zhang,Lin Ge,Wencheng Liu,Zixin Yang
Emerging pollutants, such asN-acetyl-para-aminophenol, pose significant challenges to environmental sustainability, and Bi2Fe2O2(BFO) nanomaterials are an emerging class of piezoelectric materials. This study presents a novel piezoelectric-driven Fenton system based on Bi2Fe4O9nanosheets for the efficient degradation of organic pollutants. BFO nanosheets with varying thicknesses were synthesized, and their piezoelectric properties were confirmed through piezoresponse force microscopy and heavy metal ion reduction experiments. The piezoelectric electrons generated within the BFO nanosheets facilitate the in situ production of hydrogen peroxide, which in turn drives the Fenton-like reaction. Furthermore, the piezoelectric electrons enhance the redox cycling of iron in the Fenton process, boosting the overall catalytic efficiency. The energy band structure of BFO nanosheets is well-suited for this process, enabling efficient hydrogen peroxide generation and promoting Fe3+reduction. The findings demonstrate that thinner BFO nanosheets exhibit superior piezoelectric activity, leading to enhanced catalytic performance. Additionally, the incorporation of gold nanodots onto BFO nanosheets further boosts their piezocatalytic efficiency, particularly in the reduction of Cr (VI). The system exhibited robust oxidative capacity, stability, and recyclability, with reactive oxygen species (ROS) verified via electron paramagnetic resonance spectroscopy. Overall, BFO nanosheets, with their optimal energy band structure, self-supplied hydrogen peroxide, and enhanced Fe3+reduction, represent a promising, sustainable solution for advanced oxidation processes in wastewater treatment and other applications.
研究领域:
环境科学
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材料化学
·
纳米技术
·
高级氧化工艺
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水处理
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产品关联
DOI
高影响因子
Results in Chemistry
·
2025
·
IF 4.2
Shaoming Zeng,Xiaofang Lai,Hai Li,Rongtao Ji,Duan Zhao,Jikang Jian
The common water contaminant ciprofloxacin (CIP) poses a significant threat to the health of both aquatic species and humans. Current iron-sulfide-based catalysts, predominantly nanoparticles, face limitations including aqueous instability, narrow pH adaptability, and agglomeration. To overcome these bottlenecks, we developed a new iron-sulfide-based catalyst. This study used FeS micro-flakes to degrade CIP. The degradation efficiency and reusability of FeS micro-flakes were evaluated under different conditions. The results indicate that FeS micro-flakes can achieve a removal efficiency of over 99 % within 10 min at pH 6, a temperature of 30 °C, a FeS dosage of 0.8 g/L, and an H 2 O 2 concentration of 10 mmol/L. even after five cycles, the removal efficiency of FeS remained above 99 %. The hydroxyl radical (HO·) was identified as the primary reactive oxygen species (ROS) by chemical quenching experiments and electron paramagnetic resonance (EPR). These results demonstrate the exceptional performance and reusability of the FeS heterogeneous Fenton catalyst
研究领域:
环境化学
·
催化科学
·
水污染与治理
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材料科学
·
化学工程
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产品关联
DOI
高影响因子
ENVIRONMENTAL SCIENCE & TECHNOLOGY
·
2025
·
IF 11.3
Jun Wang,Ying Zhao,Qiming Zhang,Bo Tian,Yi Shen,Yang Zhang,Wei Ren,Xiaoguang Duan,Shaobin Wang
Carbocatalysts are highly effective in driving persulfate-based advanced oxidation processes (PS-AOPs) for selective removal of organic micropollutants. Conjugated nitrogen species (e.g., graphitic, pyridinic Ns) are well-known for enhancing the catalytic activity of carbon materials. However, the mechanistic role of nonconjugated nitrogen species (e.g., amine, amide) in persulfate activation remains unexplored due to their thermal instability during pyrolysis. In this study, we synthesized three-dimensional nitrogen-doped graphene aerogels (NGAs) enriched with nonconjugated nitrogen via hydrothermal assembly and systematically compared them with their pyrolytic counterparts. Hydrothermal NGAs exhibit abundant edge-located nonconjugated nitrogen species, which enhance surface hydrophilicity and accelerate mass transport to promote efficient nonradical activation of peroxydisulfate (PDS) through outer-sphere electron-transfer process (ETP). Upon pyrolysis, these nonconjugated functionalities are transformed into conjugated nitrogen embedded within the carbon lattice, improving conductivity and creating electron-rich domains that favor peroxymonosulfate (PMS) activation via inner-sphere ETP. Techno-environmental-economic assessment further demonstrated that the hydrothermal NGA/PDS system is significantly more cost-effective, requiring one-eighth the synthesis energy and only one-third the oxidant cost of PMS-based systems. This work highlights the underappreciated role of nonconjugated nitrogen in PS-AOPs and offers new insights to carbon catalysts for wastewater treatment.
研究领域:
环境科学
·
材料化学
·
高级氧化技术
·
碳催化
·
水处理技术
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产品关联
DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2025
·
IF 9.7
Yulu Zhang,Hangyang Feng,Weifeng Kong,Meijuan Bian,Yingying He,Qianwei Liang,Yanlong Sun,Chengzhi Zhou,Liguo Shen
A functionally graded high-entropy alloy catalyst FeCoNiCuRu 0.5 @nitrogen-doped carbon (FeCoNiCuRu 0.5 @NC) was designed to address catalytic function regulation and active-site stability challenges in peroxymonosulfate-based advanced oxidation processes. Featuring a spatially separated architecture with a Ru C composite shell and a polymetallic alloy core, the catalyst suppresses transition metal dissolution, reducing ion leaching by 65.5 % versus conventional counterparts. The catalyst achieved complete carbamazepine (CBZ) removal within 30 min with a rate constant (k) of 0.460 min −1 at pH 3, and singlet oxygen ( 1 O 2 ) and sulfate radicals (SO 4 •− ) were identified as the dominant active species. At pH 7, this rate constant (0.158 min −1 ) showed a twofold increase over that of FeCoNiCu@nitrogen-doped carbon (FeCoNiCu@NC) and a fivefold enhancement over that of Ru@ nitrogen-doped carbon (Ru@NC). The concentrations of SO 4 •− and 1 O 2 over FeCoNiCuRu 0.5 @NC are 1.97 and 3.38-fold higher, respectively, than those over FeCoNiCu@NC. This enhancement correlates with the superior charge transfer capability of the Ru-modified catalyst system. Remarkably, the FeCoNiCuRu 0.5 @NC demonstrates unprecedented pH tolerance (pH 3–11) and stability. Its dual-active-species configuration enables simultaneous degradation of electron-rich and electron-deficient pollutants, establishing a new paradigm for designing robust high-entropy alloy catalysts.
研究领域:
环境催化
·
材料化学
·
高级氧化过程
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污染控制化学
·
纳米催化材料
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）