APPLIED SURFACE SCIENCE
·
2018
·
IF 4.439
Lele Qiu,Yulin Yang,Guohua Dong,Debin Xia,Mengru Li,Xiao Fan,Ruiqing Fan
As for the solution-processed MAPbI 3 film, the pinholes and gaps are an inevitable and undesirable phenomenon, which can usually lead to serious interface charge recombination due to the penetration of hole transport materials in perovskite solar cells (PSCs). Herein, a hydrophobic β-NaYF 4 :Yb,Er up-conversion ultrathin layer with particle size ca. 6 nm was first applied to modify the MAPbI 3 film for optimizing the surface of perovskite film. Thereby, the corresponding PSCs yield a significantly enhanced power conversion efficiency of 15.17% compared with that (13.32%) of the pristine PSCs. Furthermore, the PSCs also have a good stability in air atmosphere (relative humidity ≤45%) because of the introduction of this hydrophobic material. After a series of detailed investigations and comparison, it can be easily concluded that the filled pinholes and gaps in perovskite films via β-NaYF 4 :Yb,Er nanoparticles is the main reason for the performance enhancement of the β-NaYF 4 :Yb,Er based PSCs, which can result in an enhanced hole extraction efficiency and reduced interface charge recombination. As a conclusion, it is a feasible and effective approach for improving the photovoltaic performance of PSCs by filling up the pinholes and gaps in perovskite films with up-conversion ultrathin layers.
研究领域:
材料科学
·
能源科学
·
纳米技术
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2023
·
IF 4.3
Han Luodan,Chen Zhiwei,Yu Chunxiao,Tang Keren,Wang Yonghao,Sun Weiming,Zhang Xi,Yao Xu,Chen Jinghua,Wu Fang,Lan Jianming
In this work, an upconversion luminescence (UCL) nanosensor for fast detection of ferric ion (Fe 3+ ) and phosphate ion (Pi) is developed based on the inner-filter effect (IFE) between NaYF 4 :Yb/Er upconversion nanoparticles (UCNPs) and Fe 3+ -hypocrellin B (HB) complex. Fe 3+ -HB complex has strong absorption band (450–650 nm), which overlaps with the green emission peak of UCNPs at 545 nm. By adding Fe 3+ and Pi, the UCNPs-HB system produces the red-shift change of absorption spectrum, which leads to the “on–off-on” process of IFE. So, with the specific recognition ability of HB for Fe 3+ and the competitive complexation of Pi for Fe 3+ , the proposed nanosensor utilizes the UCL change to achieve the detection of the targets. For the detections of Fe 3+ , the linear range is 10–600 μM with a limit of detection (LOD) of 2.62 μM, and for Pi, the linear range is 5–100 μM with a LOD of 1.25 μM. The results for selectivity, precision, and recovery test are also satisfactory. Furthermore, the real sample detection shows that the proposed nanaosensor has a great potential in environmental and biological systems. Graphical Abstract An upconversion luminescence (UCL) nanosensor based on the inner-filter effect (IFE) between upconversion nanoparticles (UCNPs) and Fe 3+ -hypocrellin B (HB) complex for the detection of Fe 3+ and phosphate ion has been proposed, which is promising to be a convenient and sensitive assay for monitoring Fe 3+ and phosphate ion in different environments and biological systems.
研究领域:
分析化学
·
环境科学
·
纳米技术
·
生物技术
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Nano Materials
·
2025
·
IF 5.5
Hanqing Liu,Yifei Zhou,Jing Xu,Le Ding,Chuan Liao,Tao Wang,Haifeng Zhou,Guangjun Zhou
High-efficiency detection of cadmium ions (Cd2+) and mercury ions (Hg2+) is crucial due to their harmful effects on the environment and human health. Here, we developed a ratiometric upconversion fluorescence (UCF)-based nanosensor by incorporating lanthanide-doped upconversion nanoparticles (UCNPs) and gold nanoparticles modified with trithiocyanuric acid (TMT-AuNPs) as specific recognition elements for the highly sensitive and selective real-time detection of Cd2+ and Hg2+. The developed nanosensor exhibited selective absorbance enhancement and UCF quenching behavior with the addition of Cd2+ and Hg2+ based on the inner filter effect (IFE). The sensitivity of the nanosensor was significantly enhanced by converting the change in absorbance into an exponential variation in UCF intensity. Therefore, the quantitative detection of Cd2+ and Hg2+ was achieved by measuring the UCF ratio I654/I540. In order to distinguish between Cd2+ and Hg2+, two biomolecules, glutathione (GSH) and ascorbic acid (AA), were used based on their different interactions with Cd2+ and Hg2+. GSH formed a specific tetrahedral complex (GSH)4Cd with Cd2+, thereby preventing Cd2+ from inducing changes in UCF intensity. In contrast, AA specifically reduced Hg2+, thereby preventing Hg2+-induced UCF changes. Thus, GSH and AA could also be detected. The limits of detection (LODs) of Cd2+, Hg2+, GSH, and AA were 2.8, 5.2, 5.1, and 7.2 nM, respectively. The designed detection platform provides a sensitive and straightforward sensing strategy for the multiplex detection of heavy metal ions and biological small molecules.
研究领域:
分析化学
·
环境科学
·
生物医学
✓ 已验证
产品关联
DOI
高影响因子
TALANTA
·
2019
·
IF 4.916
Leilei Sun,Tao Wang,Yuzhen Sun,Zexin Li,Haining Song,Bin Zhang,Guangjun Zhou,Haifeng Zhou,Jifan Hu
Dual-functional nanosensors based on small molecule regulation can be widely used due to their simplicity, high sensitivity and selectivity. Herein, glutathione (GSH) calibrated dual-functional system for GSH and cadmium ions (Cd 2+ ) detection based on fluorescence resonance energy transfer (FRET) between NH 2 –NaYF 4 :Yb,Er/NaYF 4 @SiO 2 upconversion nanoparticles (UCNPs) and gold nanoparticles (AuNPs) is designed. Unmodified AuNPs are easy to aggregate in high-salt solution and thereby quenching the red emission of UCNPs. The presence of GSH prevents the aggregation of AuNPs, so GSH can be detected by the changes in the color of solution and the recovery of red emission of UCNPs. However, Cd 2+ can interact with GSH, which makes AuNPs easy to aggregate, resulting in a gradual decrease in red emission of UCNPs. The fluorescence response of the system is linear with the concentrations of GSH and Cd 2+ in a wide range of concentrations, with low detection limits of 0.016 μM and 0.059 μM, respectively. Furthermore, the nanosensor demonstrates high selectivity for GSH and Cd 2+ detection and can be applied for the detection of GSH in human plasma and Cd 2+ in drinking water .
研究领域:
生物化学
·
分析化学
·
纳米科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Nanoscale
·
2015
·Vol. 8
·期 2
·878-888
·
IF 7.394
Yuanwei Pan,Ling'e Zhang,Leyong Zeng,Wenzhi Ren,Xueshan Xiao,Jichao Zhang,Lili Zhang,Aiguo Li,Guangming Lu,Aiguo Wu
Multidrug resistance (MDR) of cancers is still a major challenge, and it is very important to develop visualized nanoprobes for the diagnosis and treatment of drug resistant cancers. In this work, we developed a multifunctional delivery system based on DOX-encapsulated NaYF4:Yb/Er@NaGdF4 yolk–shell nanostructures for simultaneous dual-modal imaging and enhanced chemotherapy in drug resistant breast cancer. Using the large pore volume of the nanostructure, the delivery system had a high loading efficiency and excellent stability. Also, an in vitro and in vivo toxicity study showed the good biocompatibility of the as-prepared yolk–shell nanomaterials. Moreover, by nanocarrier delivery, the uptake of DOX could be greatly increased in drug resistant MCF-7/ADR cells. Compared with free DOX, the as-prepared delivery system enhanced the chemotherapy efficacy against MCF-7/ADR cells, indicating the excellent capability for overcoming MDR. Furthermore, core–shell NaYF4:Yb/Er@NaGdF4 improved the upconversion luminescence (UCL) performance, and the designed delivery system could also be applied for simultaneous UCL and magnetic resonance (MR) imaging, which could be a good candidate as a dual-modal imaging nanoprobe. Therefore, we developed a multifunctional yolk–shell delivery system, which could have potential applications as a visualized theranostic nanoprobe to overcome MDR in breast cancer.
研究领域:
纳米技术
·
癌症研究
·
材料科学
·
生物医学工程
·
药物学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ELECTROCHIMICA ACTA
·
2022
·
IF 7.336
Siqi Zhang,Shuopan Dun,Xugeng Guo,Jinglai Zhang
Introducing upconversion nanoparticles (UCNPs) or fabricating TiO 2 hollow spheres (TiO 2 -HSs) are considered two feasible strategies to enhance the photovoltaic performance of dye-sensitized solar cells (DSSCs). However, studies investigating a combination of UCNPs and TiO 2 -HSs for the application in DSSCs are still scarce. In this contribution, NaYF 4 :Yb,Er@NaGdF 4 :Nd@SiO 2 UCNPs and TiO 2 -HSs were synthesized and respectively applied as upconversion layers and scattering layers on the TiO 2 photoanode of DSSCs. The influence of different doping ratios of UCNPs on cell performance was explored. The present results reveal that the DSSCs device based on conventional P25 photoanode films incorporating the UCNPs with 10% can achieve a photovoltaic efficiency of 6.65%, showing 29.63% enhancement in comparison to the device without UCNPs. When the TiO 2 -HSs are used as scattering layers above the P25 film, the DSSCs device obtains a higher photovoltaic efficiency of 6.97%. More importantly, combining the UCNPs and TiO 2 -HSs can further enhance the photoelectrical property of DSSCs, realizing an optimal efficiency of 8.17%. Such an improvement can be attributed to a synergistic mechanism arising from the upconversion effect of UCNPs and the light scattering effect of TiO 2 -HSs. This work opens a new way of preparing composite photoanode films to improve the photovoltaic performances of DSSCs.
研究领域:
材料科学
·
能源科学
✓ 已验证
产品关联
DOI
高影响因子
MICROCHIMICA ACTA
·
2018
·Vol. 185
·期 10
·1-10
·
IF 5.705
Xu Sai,Yu Yang,Gao Yuefeng,Zhang Yanqiu,Li Xiangping,Zhang Jinsu,Wang Yunfeng,Chen Baojiu
Accurate detection of temperature and oxygen concentration at the cellular level is important in tumor diagnosis. Multifunctional nanocomposites are described that consist of upconversion luminescent nanoparticles capped with mesoporous silica and loaded with an oxygen-sensitive luminescent ruthenium complex. The nanocomposites of type NaYF 4 :Yb,Er@NaYF 4 @mSiO 2 -Ru have two modes of operation: Its red downconversion luminescence (at excitation/emission peaks of 455/606 nm) is quenched by oxygen (O 2 ), and this is used to sense and image O 2 . The green upconversion luminescence (typically acquired at excitation/emission wavelengths of 980/525 and 544 nm), in turn, is used to measure temperature. The nanocomposites were then applied to dual mode in-vitro imaging of temperature and O 2 in hepatocellular carcinoma cells (HepG-2).
A new multifunctional nanocomposite of mesoporous silica coating NaYF 4 :Yb,Er@NaYF 4 upconversion nanopaticless loaded with ruthenium (II) complex has been designed with both green upconversion and red downconversion luminescence for temperature detection, oxygen sensing and dual mode cell imaging.
研究领域:
生物医学工程
·
纳米医学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2020
·Vol. 187
·期 7
·1-8
·
IF 6.232
Wu Nengying,Wei Yuxi,Pan Lanlan,Yang Xiaolin,Qi Honglan,Gao Qiang,Zhang Chengxiao
Lateral flow immunostrips were newly designed and a sensitive and rapid fluorometric method for the determination of 8-hydroxy-2′-deoxyguanosine (8-OHdG) as a model target of small biomarker molecules was developed. The upconversion nanoparticles (UCNPs, NaYF4:Yb/Er core, and polyacrylic acid (PAA)-modified shell, size ~ 39 nm, excitation wavelength = 980 nm; emission wavelength = 540 nm) were employed as fluorescence signal material. The 8-OHdG antibody (Ab) was taken as the recognition probe while UCNP-labeled Ab was taken as the signal probe. Bovine serum albumin (BSA) was designed as carrier protein for 8-OHdG to form 8-OHdG-BSA conjugate as the capture probe. The lateral flow immunostrips were prepared by laminating a sample pad (glass fiber membrane), a test pad (nitrocellulose membrane), and adsorption pad (filter paper) on PVP backing. The capture probe was immobilized on the test zone while an IgG antibody taken as the control probe was immobilized on the control zone. When the signal probe and the sample were in sequence loaded on the sample pad, 8-OHdG analyte bound with the signal probe, and then the excess of the signal probe move along the strip and is collected by the capture probe on the test zone while the remnant signal probe is collected by the control probe on the control zone. The signal probe and capture probe were synthesized and characterized. The fluorescence intensity on the test zone was inversely proportional to the concentration of 8-OHdG for the quantitative determination while the fluorescence emission on the control zone was observed to validate the assay. The developed method showed a wide linear range from 0.10 to 10 nM, a quite low detection limit of 0.05 nM, small sample volume requirement (100 μL), short assay time (15 min), and good method reproducibility (RSD = 4.4%, nine immunostrips).
Schematic illustration of the configuration and measurement principle of lateral flow fluorescence immunostrip for 8-OHdG: (a) configuration; (b) preparation: load of capture probe (BSA-8-OHdG, 2 μL) on test zone; load of control probe (IgG Ab, 2 μL) on control zone; load of signal probe (UCNP-Ab, 16 μL) on sample pad; (c) measurement: load of sample (8-OHdG, 100 μL) on sample pad, collection, and measurement.
研究领域:
分析化学
·
纳米技术
·
生物医学工程
·
生物化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）