ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY
·
2025
·
IF 2.8
Shi Si,Zhang Zijie,Wang Rong,Xue Shiji,Fei Wanyu,Peng Yue’e
In this study, a detailed analysis of 20 per- and polyfluoroalkyl substances (PFAS), including 13 perfluorocarboxylic acids (PFCAs) (C4–C18), four perfluorosulfonic acids (PFSAs) (C4, C6, C8, C10), and three polyfluoroalkyl substances, in different environmental media of Fu River, which was the main sewage storage body, and located near the Tianhe Airport in Wuhan, China. In the surface water samples, short-chain PFAS, perfluorobutanesulfonic acid (PFBS) and perfluorobutanoic acid (PFBA) were the most prevalent, and highest concentrations of 168 ng/L and 49.7 ng/L, respectively. However, in the sediment samples, PFBS and perfluorooctane sulfonate (PFOS) were the most prevalent, and highest concentrations of 840 ng/kg and 1510 ng/kg, respectively. Meanwhile, PFOS was the most prevalent substance, with the highest concentrations measured at 23.3 μg/kg in egg yolk and 28.1 μg/kg in fish, accounting for proportions of 82% and 88%, respectively. Two new short-chain substitutes of PFOS, 6:2 clorinated polyfluoroalykyl ether sulfonate (6:2 Cl-PFESA) and 8:2 clorinated polyfluoroalykyl ether sulfonate (8:2 Cl-PFESA), emerged in sediment and fish. The PFAS in eggs, fish, and vegetables of Fu River Basin poses a potential health risk to residents according to the suggested value of the European Food Safety Agency.
研究领域:
环境科学
·
毒理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2024
·
IF 8.1
Lirong Zhao,Ruoqi Pu,Shihuai Deng,Lili Lin,Dionissios Mantzavinos,Ravi Naidu,Cheng Fang,Yongjia Lei
Per- and polyfluoroalkyl substances (PFAS) remediation remains a challenge, especially for real samples such as aqueous film-forming foams (AFFF) for fire-fighting and PFAS foam fractionate concentrates (FF) produced from the water treatment processes. In this study, electrochemical advanced oxidation process (EAOP) using boron-doped diamond (BDD) anode to activate persulfate (PS) was investigated. The results shown that the electrochemical activation of PS significantly enhanced the removal of PFAS, including oxidation and defluorination. Under the optimal conditions (initial current density of 40 mA/cm 2 , 5 mM PS, initial pH 3.8), both 50 μM PFOA and 50 μM PFOS reached ∼100 % removal within 2 h, and 60.4 % and 33.1 % defluorination, respectively. By monitoring the degradation intermediates, the degradation pathways and kinetics of PFOA and PFOS were studied, which indicated the excellent capability of BDD/PS process towards the PFAS remediation. In addition, the optimal BDD/PS process was applied to degrade AFFF and FF samples, and the total oxidizable precursor (TOP) assay was used to measure the defluorination effect. The results were unprecedented with a surprising >100 % defluorination for 28 PFAS tested. This research can contribute to the development of a sustainable and efficient technology for PFAS remediation, ultimately mitigating the environmental and health risks associated with these persistent contaminants.
研究领域:
环境科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
ENVIRONMENTAL SCIENCE & TECHNOLOGY
·
2023
·
IF 11.4
Xin Chen,Zixuan Lv,Yi Yang,Rongyan Yang,Guoqiang Shan,Lingyan Zhu
Nontarget analysis has gained prominence in screening novel perfluoroalkyl and polyfluoroalkyl substances (PFASs) in the environment, yet remaining limited in human biological matrices. In this study, 155 whole blood samples were collected from the general population in Shijiazhuang City, China. By nontarget analysis, 31 legacy and novel PFASs were assigned with the confidence level of 3 or above. For the first time, 11 PFASs were identified in human blood, including C1 and C3 perfluoroalkyl sulfonic acids (PFSAs), C4 ether PFSA, C8 ether perfluoroalkyl carboxylic acid (ether PFCA), C4–5 unsaturated perfluoroalkyl alcohols, C9–10 carboxylic acid-perfluoroalkyl sulfonamides (CA-PFSMs), and C1 perfluoroalkyl sulfonamide. It is surprising that the targeted PFASs were the highest in the suburban population which was impacted by industrial emission, while the novel PFASs identified by nontarget analysis, such as C1 PFSA and C9–11 CA-PFSMs, were the highest in the rural population who often drank contaminated groundwater. Combining the toxicity prediction results of the bioaccumulation potential, lethality to rats, and binding affinity to target proteins, C3 PFSA, C4 and C7 ether PFSAs, and C9–11 CA-PFSMs exhibit great health risks. These findings emphasize the necessity of broadening nontarget analysis in assessing the PFAS exposure risks, particularly in rural populations.
研究领域:
环境科学
·
毒理学
·
公共卫生
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF HAZARDOUS MATERIALS
·
2025
·
IF 11.3
Jianyi Wu,Lingxuan Li,Miao Chen,Meijuan Zeng,Xinlin Huang,Wenqing Tu
Per- and polyfluoroalkyl substance (PFAS) accumulation and increasing drought events pose threats to agricultural ecosystem safety. However, the mechanisms by which post-drought rehydration (PDR) modulates compensatory PFAS migration at the soil–water interface remain unclear. To address this, this study investigated PFAS translocation across overlying water (OW), soil solution, soil microbe-adsorbed fraction (SM), and other soil fractions (OF) in paddy soils under PDR conditions. The results revealed significant releases of short-chain PFASs into OW under PDR, with migration rates ranging from 2.69 to 11.07 μg/L/day. Drought further accelerated the distribution of short-chain PFASs in OW after rehydration ( β = 0.51) and inhibited their retention in SM ( β = −0.43) and OF ( β = −0.74). The compensatory migration of short-chain PFASs was regulated by both abiotic and biotic factors. In contrast, the compensatory migration of long-chain PFASs was mainly driven by biotic factors, including soil bacteria and protozoa. Soil untargeted metabolomics identified 7-chloro-L-tryptophan (associated with oxidative stress response) and N-acetyl-L-phenylalanine (associated with amino acid metabolism) as key metabolites involved in PFAS migration ( p < 0.05). Verification experiments further confirmed that these two metabolites significantly altered PFAS release at the soil–water interface ( p < 0.001). These findings provide new insights into PFAS pollution control in drought-affected paddy fields and highlight the need for targeted management strategies to ensure agricultural safety under dynamic climate conditions.
研究领域:
环境科学
·
土壤化学
·
生态毒理学
·
农业生态系统
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气候变化影响
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代谢组学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICAL CHEMISTRY
·
2025
·
IF 6.7
Jian Song,Hai-Long Qian,Shu-Ting Xu,Cheng Yang,Xiu-Ping Yan
Efficient extraction of perfluoroalkyl and polyfluoroalkyl substances (PFAS) poses a significant challenge for water treatment and food safety. Here, we report a multifunctional covalent organic framework (COF) for the selective and efficient extraction of PFAS. A facile room-temperature imine condensation of two monomers, 2,2′-bis(trifluoromethyl)-4,4′-diaminobiphenyl (BTFDA) and 1,3,5-triformylphloroglucinol (Tp), produced a multifunctional COF (TpBTFDA). TpBTFDA was rationally designed to synergistically integrate chemical moieties capable of leveraging both fluorophilic (via trifluoromethyl groups) and hydrogen bonding (via β-ketoenamine linkages) interactions with PFAS molecules. Batch adsorption experiments, coupled with systematic comparative studies against control COFs (lacking either the fluorophilic or hydrogen-bonding sites), revealed that this synergistic interplay is essential for the efficient capture of PFAS, demonstrating that both interaction mechanisms are indispensable. Consequently, the TpBTFDA exhibited exceptionally high adsorption capacities (379–521 mg g–1) for eight PFAS. The fabricated TpBTFDA was applied to develop a selective solid-phase extraction method for UHPLC-MS/MS determination of PFAS. The developed method showed a wide linear range (0.01–200 μg L–1), low detection limits (0.006–0.59 μg L–1), good precision (RSD ≤ 5.2%), and recovery (83.0–112.3%) for the accurate determination of PFAS in real water and food samples. This study underscores the potential of rationally designed COFs for effectively enriching and detecting PFAS in practical applications.
研究领域:
环境化学
·
材料科学
·
分析化学
·
水处理技术
·
食品安全
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Energies
·
2022
·Vol. 15
·期 22
·8717
·
IF 3.252
Quan Xu,Xinyi Chen,Siyang Wang,Chao Guo,Yingchun Niu,Runguo Zuo,Ziji Yang,Yang Zhou,Chunming Xu
Iron–chromium redox flow batteries (ICRFB) possess the advantage of low raw material cost, intrinsic safety, long charge–discharge cycle life, good life-cycle economy, and environmental friendliness, which has attracted attention from academia and industry over time. The proton exchange membrane (PEM) is an important part of the ICRFB system, impacting the efficiency and lifetime of the battery. Currently, the most widely used PEMs in the market are per-fluorinated sulfonic acid (PFSA) membranes, which possess high electrolyte stability and achieve the separation of positive and negative electrolytes. In addition, the complex preparation process and extremely high market price limited the usage of PEM in ICRFB. In this paper, we developed a remanufactured membrane (RM) strategy from waste PFSA resins. The RM has higher electrical conductivity and better proton transport ability than the commodity membrane N212. In the cell performance test, the RM exhibits similar coulombic efficiency (CE) as N212 at different current densities, which is stabilized at over 95%. Furthermore, the voltage efficiency (VE) and energy efficiency (EE) of the RM are improved compared to N212. At a current strength of 140 mA cm−2, the degree of energy loss is lower in the RM, and after 60 cycles, the capacity decay rate is lower by only 16.66%, leading to long-term battery life. It is a cost-effective method for membrane recovery and reformulation, which is suitable for large-scale application of ICRFB in the future.
研究领域:
材料科学
·
能源技术
·
环境工程
✓ 已验证
DOI
高影响因子
Environment & Health
·
2025
·
IF 6.3
Chuanzi Gao,Feng Quan,Wenhui Qiu,Yi Zheng
This study investigates the presence and health implications of per- and polyfluoroalkyl substances (PFAS) in human serum samples collected from white-collar workers in an industrialized region of China. Our research offers fresh insights into the underexplored area of nonoccupational PFAS exposure among white-collar workers, shedding light on health risks linked to industrial PFAS pollution. Seven PFAS compounds were measured. Perfluorooctanoic acid (PFOA) and perfluorooctanesulfonate (PFOS) emerged as predominant pollutants, with Σ7PFAS concentrations averaging 65.486 ng/mL. Gender differences showed higher serum Σ7PFAS levels in males, and age-related analyses suggested PFAS accumulation over time, with higher concentrations in older groups. Additionally, significant correlations were found between PFAS concentrations and biomarkers of oxidative stress and immune interference, specifically malondialdehyde (MDA) and immunoglobulin M (IgM), indicating that PFAS exposure may contribute to oxidative damage and potential immunosuppression. The study highlights regional and international variations in PFAS serum concentrations, underscoring the influence of industrial activities on PFAS exposure and expanding on the established links between PFAS exposure and health outcomes. These findings call for targeted strategies to mitigate PFAS exposure in high-risk regions and warrant further research on PFAS health impacts, especially in regard to immune interference.
研究领域:
环境科学
·
公共卫生
·
免疫学
·
流行病学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Di Shen,Haojie Yu,Li Wang,Yu Wang,Jingyi Feng,Chengjiang Li
The phenylborate-ester-cross-linked hydrogel microneedle patch (MNP) was promising in the diabetic field for the glucose-responsive insulin-delivering property and simple fabrication process. However, the unfit design of the charging microneedle network limited the improvement of blood-glucose regulating performances. In this work, insulin-loaded phenylborate-ester-cross-linked MNPs, with the polyzwitterion property, were constructed based on the modified ε-polylysine and poly(vinyl alcohol). The relationship between the charging nature of the MNP network and insulin release was verified by regulating the content of postprotonated positively charged amino groups. The elaborately designed MNP possessed improved glucose-responsive insulin-delivering performance. The in vivo study revealed the satisfactory results on blood-glucose regulation by the optimized MNP under the mimic three-meal-per-day mode. Moreover, the insulin bioactivity in the MNP could be maintained for 2 weeks under 25 °C. In summary, this work developed an effective strategy to improve the glucose-responsive phenylborate-ester-cross-linked MNP and enhance its potential for clinical transformation.
研究领域:
药学
·
生物医学工程
·
糖尿病研究
✓ 已验证
DOI
PubMed
高影响因子
WATER RESEARCH
·
2025
·
IF 12.4
Chunlin Zhai,Kunpeng Zhang,Yanling Liu,Shengji Xia
Highly negatively charged nanofiltration membranes with tailored pore sizes can effectively reject trace per- and polyfluoroalkyl substances (PFAS) while allowing the passage of beneficial mineral ions, making them ideal for advanced drinking water purification. This study proposed a novel dual-component-assisted interfacial polymerization (IP) strategy aiming at enhancing membrane selectivity between PFAS and mineral ions. The step-wise involvement of p-Phenylenediamine as the aqueous co-monomer and 1,3,5-triformyl phloroglucinol as the pre-loading organic phase properly tailored the IP kinetics for polyamide layer formation. This strategy achieved superior effect compared to others adopting single component or mixed organic phase, yielding high-performance membranes characterized by looser structures, higher negative charge density, thinner thickness, and enhanced hydrophilicity. The optimal membrane demonstrated a high water permeance of 20.4 L m −2 h −1 bar −1 , over 88 % rejections for six kinds of PFAS (300–514 Da), and a Ca 2+ /PFAS selectivity exceeding 37 when treating practical tap water, surpassing numerous commercial and previously developed membranes. Furthermore, the novel membrane exhibited excellent long-term stability and improved resistance to organic fouling and gypsum scaling. This study presents a promising solution of nanofiltration for drinking water treatment requiring efficient removal of trace PFAS and high preservation of mineral ions.
研究领域:
环境科学
·
膜技术
·
水处理
·
高分子化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Jia Liu,Ming Yang,Congwu Liu,Jiechen Qi,Ying Liang,Wei Wei,Peng Shao,Shili Tian,Xiaofang Chen,Xiaomei Zhang,Yong Zhang,Tengwen Yin,Zhuoliang Huang,Yanju Liu
Phytoremediation techniques for per - and polyfluoroalkyl substances (PFAS) contamination of water have recently received considerable global attention, yet the quantitative method for measuring multiple PFAS in hydrophytes is limited. This study addressed this critical gap by developing a highly sensitive method for the simultaneous determination of 15 PFAS in 8 hydrophytes, including emergent plants, floating plants, floating-leave plants, and submerged plants. By leveraging the combination of ultrasonic extraction and ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS), the method attained remarkable accuracy and sensitivity. Hydrophyte samples were extracted using 2.0 % NH 4 OH-MeOH (methanol) ( v /v) and purified with ENVI-Carb solid-phase extraction cartridges (500 mg/6 cc), ensuring efficient recovery and minimal matrix interference. PFAS separation was performed on a Waters ACQUITY UPLC BEH C 18 column (100 mm × 2.1 mm, 1.7 μm), with ionization in negative electrospray ionization (ESI-) mode, and detection in MS E mode. The method demonstrated outstanding performance, with excellent linearity (correlation coefficients ( R 2 ) > 0.99), low method detection limits (MDLs: 0.025–5.0 ng g −1 ), and method quantification limits (MQLs: 0.05–12.5 ng g −1 ). Over 90 % of matrix spiked recoveries at three levels ranged between 60 %–120 %, with relative standard deviations (RSDs) within 20 %, and no significant matrix effects were observed. Herein, the highly sensitive and accurate method is enable simultaneous PFAS quantification across diverse hydrophyte matrices, offering a robust and practical tool for monitoring and evaluating PFAS contamination in aquatic ecosystems. Its broad applicability to various hydrophyte types further underscore its utility in advancing phytoremediation research.
研究领域:
环境科学
·
分析化学
·
植物学
·
生态毒理学
·
水污染控制
✓ 已验证
产品关联
DOI
高影响因子
CHEMOSPHERE
·
2024
·
IF 8.1
Xue Zhang,Shiyi Wang,Xingyi Zhu,Donghai Zhu,Wei Wang,Bin Wang,Shubo Deng,Gang Yu
Covalent organic frameworks (COFs) demonstrate remarkable potential for adsorbing per/polyfluoroalkyl substances (PFAS). Nevertheless, the challenge of recycling powdered COFs hampers their practical application in water treatment. In this research, a quaternary amine COF with inherent positive surface charge was synthesised to adsorb perfluorooctanoic acid (PFOA) via electrostatic interactions. The COF was then combined with chitosan (CS) through a simple dissolution-evaporation process, resulting in a composite gel material termed COF@CS. The findings indicated that the adsorption capacity of COF@CS significantly surpassed that of the original COF and CS. According to the Langmuir model, COF@CS achieved a maximum PFOA capacity of 2.8 mmol g −1 at pH 5. Furthermore, the adsorption rate increased significantly to 6.2 mmol g −1 h −1 , compared to 5.9 mmol g −1 h −1 for COF and 3.4 mmol g −1 h −1 for CS. Notably, COF@CS exhibited excellent removal efficacy for ten other types of PFAS. Moreover, COF@CS could be successfully regenerated using a mixture of 70% ethanol and 1 wt% NaCl, and it exhibited stable reusability for up to five cycles. X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FTIR) characterisation, and theoretical calculations revealed that the quaternary amine functional group in COF served as the primary adsorption site in the composite gel material, while the protonated amino group on CS enhanced PFOA adsorption through electrostatic interaction. This study highlights the significant practical potential of COF@CS in the removal of PFAS from aqueous solution and environmental remediation.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Water
·
2025
·Vol. 17
·期 2
·149
·
IF 3
Chenyu Chen,Ying Wang,Fei Chen,Xinyue Wang,Qiao Zhang,Jialong Sun,Si Li,Qiang Chen,Fangze Shang,Hui Zhang
Per- and polyfluoroalkyl substances (PFAS) have become a well-known class of anthropogenic pollutants in coastal regions. It is known that PFAS primarily enter the sea from nearshore sources, dry deposition, and wet deposition. However, the contribution of offshore sources to PFAS pollution in the sea remains poorly understood. Our study aims to investigate the occurrence of 74 PFAS across 15 groups in a coastal region of eastern China and to characterize their spatial distribution by focusing on the critical roles of both nearshore and offshore sources. Results revealed that 26 PFAS were detected in the coastal region (i.e., Ou River and Wenzhou Bay), with detection frequencies ranging from 4.3% to 100.0%. Notably, over 10 PFAS were detected for the first time in the region, such as perfluorooctane sulfonamide (FOSA), hexafluoropropylene oxide dimer acid (HFPO-DA), and 6:2 fluorotelomer sulfonic acid (6:2 FTSA), among others. The concentrations of detected PFAS ranged from 0.0018 to 76.31 ng/L, with perfluorooctanoic acid (PFOA) as the dominant congener. Spatial analysis indicated that the nearshore area was more severely polluted compared to the offshore area, with specific hotspots identified near industrialized areas. However, the distribution of certain PFAS, such as perfluorobutane sulfonic acid (PFBS) and perfluoro-3,6-dioxaheptanoic acid (PFDHA), exhibited a contrasting pattern, with higher concentrations observed in the offshore area and near island perimeters. These findings suggest that PFAS pollution in Wenzhou Bay originates from both nearshore and offshore sources, highlighting a complex interplay between nearshore and island-related activities.
研究领域:
环境科学
·
海洋学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）