Marine Drugs
·
2021
·Vol. 19
·期 2
·92
·
IF 5.118
Yue Sui,Yue Gu,Yujing Lu,Chenxu Yu,Jie Zheng,Hang Qi
Fucoxanthin (FX), a natural carotenoid found in seaweed with multiple functional activities, is unstable with a poor water solubility that limits its utilization. This study aimed to improve FX’s stability and bioavailability via the nano-encapsulation of FX in polyvinylpyrrolidone (PVP)-coated[email protected]nanoparticles (NPs). The[email protected]NPs were evaluated in terms of their morphology, stability, encapsulation efficiency (EE), loading capacity (LC), and in vitro release to optimize the encapsulation parameters, and a 1:8 FX:PVP ratio was found to perform the best with the highest EE (85.50 ± 0.19%) and LC (10.68 ± 0.15%) and improved FX stability. In addition, the[email protected]NPs were shown to effectively deliver FX into Caco-2 cancer cells, and the accumulation of FX in these cancer cells showed pro-oxidative activities to ameliorate H2O2-induced damage and cell death. The[email protected]NPs could potentially become a new therapeutical approach for targeted cancer treatment.Keywords:fucoxanthin;nanoparticles;Caco-2 cells;pro-oxidation;targeted cell death
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高影响因子
SCIENCE OF THE TOTAL ENVIRONMENT
·
2021
·
IF 7.963
Di Chen,Zhang fa Tong,Zhiqiang Xiong,Xuejiao Zhang,Qing Zhao,Siyu Zhang
Layered black phosphorus (LBP) is regarded as a promising two-dimensional nanomaterial in various application fields. As bare LBP is unstable in humid environment , many modification methods have been developed recently. However, environmental risks of modified LBP nanomaterials are largely unknown. Herein, by sonication and in-situ surface-confined synthesis, polyvinylpyrrolidone (PVP) coated LBP (LBP/PVP), and zeolitic imidazolate framework-67 (ZIF-67) modified LBP (LBP/PVP-ZIF-67) nanomaterials were synthesized. Environmental stability and toxicity of the modified nanomaterials were compared with bare LBP. Results show that LBP/PVP-ZIF-67 exhibits excellent photothermal performance, and higher potential in electrochemical hydrogen evolution than bare LBP or LBP/PVP. Characteristic visible light absorbance at 593 nm was introduced into the nanomaterial by ZIF-67. LBP/PVP has stability in aqueous environment or cytotoxicity similar to LBP. LBP/PVP-ZIF-67 is completely stable in water within 120 h, in contrast to over 30% degradation of LBP or LBP/PVP. More than 50% of LBP in the LBP/PVP-ZIF-67 can degrade to dissolvable phosphorus in oxygenated water after 17 days, indicating the nanomaterial will not be persistent in the environment. Moreover, modification with ZIF-67 can reduce cytotoxicity of LBP. Therefore, this study develops a safe strategy to modify LBP and provides basic information for ecological risk assessment of LBP based materials.
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Nanomaterials
·
2020
·Vol. 10
·期 9
·1624
·
IF 4.324
Haian Xia,Jiahuan An,Weizi Zhang
The metal–support interaction (MSI) has a remarkable effect on the catalytic properties, but how to precisely modulate its degree remains a huge challenge. Herein, polyvinylpyrrolidone (PVP) with three different molecular weights (MWs) (24, 58, and 130 kDa) was used as a capping agent to fabricate Ag nanoparticles (NPs) supported on ZrO2. The physiochemical properties of the catalysts were characterized by X-ray diffraction (XRD), Transmission Electron Microscope (TEM), X-ray Photoelectron Spectroscopy (XPS), and Fourier transform infrared (FT-IR) techniques. The impacts of MSI on the catalytic activity and reaction kinetics for aerobic oxidation of 5-hydroxymethylfurfural (HMF) were investigated. The results showed that the introduction of PVP with various MWs could efficiently tailor the interfacial interactions and charge transfers (CT) among PVP, the support, and Ag NPs, thereby affecting the oxidation activity of HMF. The turnover number (TON) for HMF oxidation decreases in the order of unsupported colloidal Ag clusters > Ag/ZrO2(58,000) > Ag/ZrO2(130,000) > Ag/ZrO2(24,000) > Ag/ZrO2. The reason for this large difference in the catalytic activity for HMF oxidation is that various MWs of PVP result in a change of MSI, thereby facilitating CT from PVP to Ag metal sites. This study offers a new strategy for modulating MSI by varying the MW of capping agents, thereby tuning the catalytic properties in the oxidation of HMF.Keywords:metal–support interaction;molecular weight;capping agent;PVP;HMF oxidation
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APPLIED SURFACE SCIENCE
·
2019
·
IF 5.155
Mu Li,Lili Wu,Chaocan Zhang,Wanyu Chen,Cong Liu
Membrane technology has received wide attention as it plays an important role in water treatment process. However, membrane fouling results in a decrease in water permeation flux and separation effect, which lead to degraded membrane lifespan. A facile and novel strategy to form a multifunctional modified coating on the membrane surface by using the one-step assembly coating on the basis of tannin acid had been reported in this work. Tannin acid is a plant-derived polyphenolic substance that is hydrophilic and bactericidal. As a common nonionic polymer, polyvinylpyrrolidone (PVP) has a hydrophobic interaction and hydrogen bonding with TA and is beneficial to improve the hydrophilicity and antifouling performance of the substrate. However, the benefits of coating on the membrane have been limited due to the strong complexing ability of TA and PVP in aqueous solution. Herein, 50% N , N -dimethylformamide (DMF) aqueous solution were found that promoted the co-deposition of TA and PVP on the surface of the membrane. The catechol-rich polyphenol coating provides versatile properties on the membrane surface, including ultra-high pure water flux, high antifouling properties, recyclability, and a certain degree of antimicrobial performance. Moreover, the TA-PVP coating imparts a binding site for binding metal ions that allows it to capture metal ions through complexation and immobilization on the coating. The modified membranes showed more significant antifouling performance after iron ions have been complexed, and showed stronger bactericidal activity after silver ions have been complexed.
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CARBOHYDRATE POLYMERS
·
2019
·
IF 6.044
Guodong Li,Dehai Yu,Zhaoping Song,Huili Wang,Wenxia Liu
It is a significant challenge to reduce the sheet formation time and simultaneously sustain high transparency and good formation of nanostructured paper made of cellulose fibrils. In this study, a new strategy was developed for expediting the filtration but avoiding the flocculation of cellulose fibrils by using polyvinylpyrrolidone (PVP) and Laponite as dispersants to reduce the viscosity of the cellulose fibril aqueous dispersion. By adding 0.5 % PVP and 0.2 % Laponite to the cellulose fibril dispersion, the sheet formation time was reduced from 135.3–53.0 min, and the transmittance of the nanostructured paper was increased from 82.8%–89.8 %. The addition of PVP and Laponite significantly reduced the roughness and density but improved the tensile strength of the nanostructured paper. This study provides an approach for simultaneously improving the drainability, transparency, tensile strength, and smoothness of cellulose nanostructured paper made of cellulose fibrils.
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ACS Applied Nano Materials
·
2018
·
IF 0
Wuzhu Sun,Weiyi Yang,Zhengchao Xu,Qi Li
A novel and environmentally benign approach was developed to create a Fe3O4@SiO2 core–shell structure supported Pd catalyst consisting of a superparamagnetic Fe3O4 nanosphere core, a SiO2 shell with a rough surface, Pd nanoparticles deposited on a SiO2 shell, and a cross-linked polyvinylpyrrolidone (PVP) layer. It was found that both adsorbed PVP and SiO2 shell with a rough surface from the surface-protected etching process were critical to obtain the uniform PdO deposition, while the cross-linked PVP layer could effectively anchor and protect active Pd nanoparticles to enhance their stability to resist detachment from the catalyst support and improve the reusability of the catalyst. Because of its superparamagnetic behavior, it could disperse well in aqueous solution without external magnetic field and be separated easily from aqueous solution when an external magnetic field was present. It demonstrated a high catalytic activity, desirable N2 product selectivity over 99.7%, and good reusability for the catalytic nitrite reduction in aqueous solution.
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TALANTA
·
2015
·
IF 3.545
Zhiguang Liu,Yujing Guo,Chuan Dong
In this report, a new nanocomposite was successfully synthesized by chemical deposition of nickel nanoparticles (NiNPs) on polyvinylpyrrolidone (PVP) stabilized graphene nanosheets (GNs) with chitosan (CS) as the protective coating. The as obtained nanocomposite (PVP–GNs–NiNPs–CS) was characterized by X-ray photoelectron spectroscopy (XPS) and transmission electron microscopy (TEM). Benefiting from the synergistic effect of GNs (large surface area and high conductivity), NiNPs (high electrocatalytic activity towards the glucose oxidation) and CS (good film-forming and antifouling ability), a nonenzymatic electrochemical glucose sensor was established. The nanocomposite displays greatly enhanced electrocatalytic activity towards the glucose oxidation in NaOH solution. The PVP–GNs–NiNPs–CS based electrochemical glucose sensor demonstrates good sensitivity, wide linear range (0.1 μM–0.5 mM), outstanding detection limit (30 nM), attractive selectivity , good reproducibility, high stability as well as prominent feasibility for the real sample analysis. The proposed experiment might open up a new possibility for widespread use of non-enzymatic sensors for monitoring blood glucose owing to its advantages of low cost, simple preparation and excellent properties for glucose detection.
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JOURNAL OF MEMBRANE SCIENCE
·
2024
·
IF 8.4
Huan Wang,Jing Li,Wen Hao,Qiuyu Zhang,Miao Tian
Optimizing the performance of thin-film composite polyamide (TFC-PA) membranes is crucial for enhancing filtration efficiency across diverse applications. This study investigated the role of polyvinylpyrrolidone (PVP) in modulating the diffusion kinetics of piperazine (PIP) during the interfacial polymerization (IP) process, essential for membrane fabrication. By incorporating PVP into the aqueous phase, and combining it with selected inorganic salts such as sodium chloride (NaCl), the formation of a more controlled Turing-like nanostructure within the PA layer was achieved, significantly improving membrane permeability and structural uniformity. Employing molecular simulations alongside diverse characterization techniques, the mechanisms by which PVP and NaCl additives influence the diffusion of PIP monomers at the water-oil interface were elucidated. The optimized membranes demonstrated a substantial increase in water permeability, achieving 16.2 ± 0.9 L m −2 h −1 bar −1 , and an impressive sodium sulfate (Na 2 SO 4 ) rejection rate of 97.5 ± 0.6 %, outperforming untreated nanofiltration (NF) membranes. The findings provide a deeper understanding of the molecular interactions during IP and open avenues for the development of advanced filtration membranes with tailored properties.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2024
·
IF 4.9
Yongwei Cai,Yao Chen,Ruru Wang,Jianxiang Li,Hong Yang,Yuanju Li,Danni Qu
Developing a superhydrophilic/underwater oleophobic mesh membrane using an economical and eco-friendly method is still challenging to achieve high efficiency for oily wastewater separation. In this study, we proposed a novel approach to fabricate superhydrophilic/underwater oleophobic PVP/ZIF-8 coatings on stainless steel (SS) mesh using a low-cost and environmentally friendly electrodeposition method. The prepared PVP/ZIF-8@SS mesh membrane exhibited remarkable self-cleaning and anti-oil-fouling properties, along with a strong chemical robustness in extreme environments. Additionally, the mesh membrane demonstrated strong antimicrobial ability and excellent corrosion resistance property. The mesh membrane also showed promising potential in gravitational oil-water separation and oil recovery, achieving a separation efficiency of 99.0% and a water flux of 3.8 × 10 3 L·m −2 ·h −1 for rapeseed oil-water mixtures. Importantly, the PVP/ZIF-8@SS mesh membrane maintained exceptional separation efficiency, high water flux, and underwater oleophobicity properties even after undergoing 35 cycles of oil-water separations. The oil-water separation mechanism of the PVP/ZIF-8@SS mesh membrane suggested that the surface of the mesh membrane contained PVP/ZIF-8 particles with a significant negative charge. These particles preferentially interacted with positively charged water, facilitating the rapid passage of water phase through the pores, while impeding the permeation of negatively charged oil phase. This research provides an effective strategy for practical applications, including marine oil spill cleanup, oily wastewater treatment, and recycling of residual cooking oil in the restaurant industry.
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JOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS
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2025
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IF 4.9
Yaqing Liu,Zhenghao Fu,Ling Yang,Jing Zou,Linjun Shao,Guiying Xing,Xian-Man Zhang
Cellulose acetate (CA) has been widely employed in drug delivery systems for immediate and sustained release of poorly water-soluble drugs. This study aimed to investigate how the solubility and condensed structure of CA based fiber matrices influence the release performance of ibuprofen (IBU). IBU-loaded CA/polyvinylpyrrolidone (PVP) fibers were fabricated via electrospinning with water-soluble PVP as the co-spinning polymer to modulate the fiber solubility. Scanning electron microscopy (SEM) confirmed the preparation of uniform fibers with diameters of 280 nm to 1.550 μm. Fourier transform infrared spectroscopy (FT-IR) revealed the intermolecular interactions between CA and PVP, while FT-IR and X-ray diffraction (XRD) verified the homogeneous dispersion of IBU in an amorphous state within the fibers. Positron annihilation lifetime spectroscopy (PALS) elucidated the effects of annealing temperature on free volume characteristics, demonstrating that higher annealing temperatures reduced free volume size and intensity. In vitro drug release studies demonstrated that IBU release rates increased with higher PVP content due to enhanced dissolution while elevated annealing temperatures slowed release kinetics by reducing free volume fraction. The release kinetics followed first-order behavior with the highest linearity, suggesting the Fickian diffusion release mechanism. These findings highlight the ability to control drug release behavior by tailoring the dissolubility and condensed structure of fiber matrices, offering a promising strategy for optimizing drug delivery systems.
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RSC Advances
·
2014
·Vol. 4
·期 108
·63162-63170
·
IF 3.708
Meijing Wang,Yi-nan Wu,Jingyi Shen,Meimei Zhou,Fengting Li,Bingru Zhang
In this work, porous carbon materials produced from poly(furfuryl alcohol) (PFA)/polyvinylpyrrolidone/silica composite electrospun fibers have been prepared by sol–gel, carbonization and etching processes. PFA acts as carbon source, tetraethyl orthosilicate (TEOS) serves as a template and poly(propylene oxide)-block-poly(ethylene oxide)-block-poly(propylene oxide) triblock copolymer Pluronic F127 works as a structure-directing agent. Three samples (C-1, C-2 and C-3) with different pore structures have been prepared. The structures of the pores are demonstrated to be dependent on the amount of TEOS and the presence or absence of F127 by means of various characterization methods. After the carbonization process, carbon material yields of 35.5%, 38.6% and 40.3% are obtained, corresponding to the samples of electrospun nanofibers M-1, M-2 and M-3, respectively. When further treated by the hydrofluoric acid (HF) etching, the regular morphology of the electrospun nanofibers disappears gradually by prolonging the etching time, and the as-obtained typical product C-3 has a high specific surface area (SSA) of 897 m2 g−1 and a specific capacitance of 205.5 F g−1 at the scan rate of 20 mV s−1 in KOH electrolyte solution. It is revealed that the structure of the pores and the high SSA are responsible for the excellent electrochemical performance of the porous carbon materials. According to the results, the typical product C-3 is a promising electrode material for electrical double-layer capacitors.
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CELLULOSE
·
2019
·Vol. 27
·期 2
·955-967
·
IF 3.917
Jiang Lang,Li Ke,Yang Huiyu,Liu Xin,Li Wei,Xu Weilin,Deng Bo
Good mechanical properties of electrospun nanofiber membranes are essential for their successful application for commercial applications by providing sufficient mechanical strength to withstand severe operational conditions and guarantee structural integrity. Cellulose acetate nanofiber membranes modified with both polyvinylpyrrolidone (PVP) coated cellulose nanocrystals (CNC@PVP) and pristine CNCs were prepared using the reinforcement concentration varying from 0 to 0.135 wt%. The stability of dispersed CNCs and CNC@PVP in dimethylacetamide (DMAc) were compared visually. The apparent viscosity as a function of shear rate was compared for both CNCs and CNC@PVP in electrospun solution. Internal structure of obtained nanofiber membranes were compared using scanning electron microscopy to reveal the nanofibers diameter and its distribution. FTIR was used to disclose the different chemical structure of the two groups of membranes. Mechanical properties of nanofiber membranes were also compared. Finally, the thermogravimetric analysis was utilized to compare the thermal stability of different nanofiber membranes.
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