Frontiers in Chemistry
·
2022
·
IF 5.545
Hao Ruixin,Luo Shanshan,Wang Feiyan,Pan Xinyu,Yao Jing,Wu Jielian,Fang Haihong,Li Wenkui
ZnO quantum dots (QDs) have received much attention as biomarkers and drug delivery systems in cancer treatment, due to their low cost, ease of preparation, and pH-responsive degradation. However, its applications are limited by the low quantum yield and light absorption. In this work, a lanthanum-doped zinc oxide (La-ZnO) QDs-based drug delivery platform was constructed. The results show that 4% La doping is the most beneficial for improving the fluorescent properties of the ZnO QDs. After loading the drug, the cell activity was 15% at ZnO@DOX and 12% at La-ZnO@DOX. According to in vitro and in vivo experiment results, the La-ZnO QDs show enhancement of the antitumor effect. Dual enhancement of fluorescence and anti-tumor effects make La-ZnO QDs promising as a drug delivery system in cancer treatment.
研究领域:
生物医学工程
·
纳米医学
·
肿瘤学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2021
·
IF 5.268
Yuyan Yan,Yafei Hou,Huijun Zhang,Wenqing Gao,Renlu Han,Jiancheng Yu,Long Xu,Keqi Tang
Chemodynamic therapy (CDT) is an emerging tumour-specific therapeutic technology. However, the relatively insufficient catalytic activity of CDT agents in the tumour microenvironment (TME) limits their biomedical application. In addition, severe hypoxia and glutathione (GSH) overexpression in the TME greatly limit the antitumour efficiency of monotherapy. Herein, a cancer cell membrane-camouflaged and ultrasmall CeO 2 -decorated MnO 2 (mMC) composite is developed for amplified CDT, photodynamic therapy (PDT) and photothermal therapy (PTT). Due to the homotypic targeting ability of cancer cell membranes, mMC nanoparticles preferentially accumulate in tumour tissue. In the TME, CeO 2 acts as a highly efficient CDT agent to convert endogenous H 2 O 2 to toxic reactive oxygen species (ROS) for killing cancer cells. Meanwhile, MnO 2 irradiated with near-infrared (NIR) light displays prominent hyperthermia and ROS generation performance to perform PTT and PDT. Moreover, MnO 2 can produce oxygen to ameliorate hypoxia and deplete GSH to relieve the antioxidant capability of tumours, which is beneficial to the simultaneous augmentation of PDT and CDT. Most importantly, the catalytic activity of CeO 2 was greatly improved by hyperthermia. Consequently, a significantly enhanced therapeutic efficiency was obtained by the above multiple synergistic effects. This work provides a proof of concept for amplified tumour therapy by synchronously self-supplying oxygen, consuming GSH, and enhancing catalytic activity.
研究领域:
生物医学工程
·
肿瘤治疗研究
✓ 已验证
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2019
·
IF 6.393
Jinling Zhang,Mengxiang Shang,Yao Gao,Jianyue Yan,Wenbo Song
High visible-light active materials with boosted photoelectric conversion efficiency are the key to fabricate high-performance photoelectrochemical (PEC) sensor. Herein, we report in-situ formation of VS 2 QDs-Bi 2 S 3 heterostructure for promising application in constructing PEC aptasensor. Dramatically enhanced photoelectric conversion capacity is verified by photoluminescence spectroscopy (PL), electrochemical impedance spectroscopy (EIS) and PEC measurements. The intrinsic metallic feature of VS 2 , efficient visible light absorption of Bi 2 S 3 nanotube, and well-aliened band structure between them are responsible to substantially enhanced photocurrent. By covalently linking 5′-NH 2 -terminated lysozyme (Lys) aptamer on the VS 2 QDs-Bi 2 S 3 heterostructure, a self-powered PEC aptasensor for Lys is constructed. Under optimal conditions, ultrasensitive and selective detection of Lys is established in a wide linear range of 3.5 pM-70 nM with good selectivity and stability. The detection limit is 1.1 pM. Trace monitoring Lys in biological systems is realized with desired accuracy and satisfactory recovery. This work illustrates the prospect of VS 2 QDs-based heterostructure for PEC sensing and possible photocatalytic applications.
研究领域:
生物传感
·
材料科学
·
分析化学
✓ 已验证
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2018
·
IF 5.667
Yunyun Cheng,Huan Wang,Li Li,Ting Han,Xiao Liang,Lijie Dong
Flexible humidity-sensitive materials have drawn increasing attention due to their vital function in monitoring ambient humidity for tactile sensors, allowing them to approach the functionality of human skin. In this work, an electrospun polyvinyl alcohol (PVA)-based nanofiber film comprising surface-carboxylated CdSe/Cd x Zn 1-x S quantum dots (QDs) is fabricated as a high-performance flexible humidity sensing material, based on the relationship between its photoluminescence (PL) and the humidity. The as-prepared film shows excellent PL-humidity linearity, a wide sensing range from 10% to 90% relative humidity, a relatively fast response time, good recoverability, and flexibility. The humidity sensing mechanism can be attributed to the breaking and reforming of hydrogen bonds and proton transfer occurring at the PVA-QD interfaces. This flexible humidity-sensitive material is believed to be a good candidate for humidity-sensitive components in electronic skin.
研究领域:
材料科学
·
纳米技术
·
传感技术
✓ 已验证
DOI
高影响因子
Materials Chemistry Frontiers
·
2024
·
IF 6
Yanan Zhang,Nuo Xu,Jipeng Xu,Chi Shan,Junlei Chen,Liyuan Guo,Long Qin,Fan Wu,Wenhuan Huang
The micro/nano-structural design of 2D-interlayers greatly enhances the electrochemical energy and kinetics as supercapacitor electrode. Herein, a hetero-Co9S8 QDs doped 2D CoNi-LDH with the proper content was constructed through diverse sulfurization times, showing 3D flower-like microsphere. The highly dispersed active QDs on 2D layers promoted both rapid ion/electron transfer kinetics and electrochemical storage capacity, which were evidenced by experiments and density function theory calculations. As a result, the assembled hybrid supercapacitor QDs-Co9S8/CoNi-LDH//activated carbon displays a maximum energy density of 33.3 Wh·kg-1 at a power density of 820.0 W·kg-1. Furthermore, the in-depth analysis of interlayer ion diffusion and formation of quantum dots in heterostructure provide a good way for synthesizing high performance electrode materials with adjustable size and composition.
研究领域:
材料科学
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
Nanoscale Advances
·
2025
·
IF 4.6
Yuquan Chen,Perumal Veeramalai Chandrasekar,Chuanbo Li,Sree Pammi,Jagadeesh Babu Bellam,Xiaoming Zhang,Peipei Ma
Broad band photodetectors are found to be the inevitable component both in scientific and industrial field. Here, PbSe colloidal QDs prepared by a simple, inexpensive hot injection method were used to fabricate ultra broadband photodetectors with visible to near-infrared sensing capabilities. The as-fabricated photodetector has a wide spectral response and a stable photoelectric response to lasers with wavelengths ranging from 405 nm to 1550 nm. The photovoltaic detector responsivity is 1.43 mA/W at 405 nm, 4.67 mA/W at 980 nm and 0.2 mA/W at1550 nm. The device with optimized structure provides the maximum Voc of 250 mV under 780 nm light illumination and 100 mV even under 1550 nm illumination. Specifically, the detectivity value reaches up to 4.54×109 Jones at 1550 nm laser illumination with intensity of 0.41 mW/cm2. As a result, the current study's findings serve as the foundation for the creation of a broad band photodetector that can detect light from visible to near infrared spectrum.
研究领域:
材料科学
·
光电工程
✓ 已验证
产品关联
DOI
PubMed
高影响因子
LANGMUIR
·
2025
·
IF 3.9
Haobo Zhu,Zhuo Wang,Lu Yuan,Junke Xie,Yalan Guo
Self-warning coatings are functional materials capable of converting subtle microscopic corrosion signals into macroscopically detectable optical responses; however, the high cost of conventional fillers and the complexity of core–shell fabrication hinder their large-scale application. To address this, we developed a composite material based on self-assembled ZnO quantum dots@ZIF-8 (ZnO QDs@ZIF-8) for low-cost corrosion monitoring of bronze artifacts. The material was synthesized via ultrasound-assisted preparation of ZnO quantum dots, followed by one-step encapsulation with ZIF-8 using 2-methylimidazole, resulting in a uniform core–shell structure. This process is simple and efficient (completed within 1 h at a cost of $0.05 per gram), and the resulting composite enables highly sensitive detection of Cu2+ through a fluorescence quenching mechanism (LOD = 78 nM). When integrated into an acrylic coating, the material can convert invisible corrosion signals into visible optical changes, achieving self-warning of corrosion. This offers a scalable solution for cultural heritage preservation and holds potential for extension to industrial monitoring systems.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2025
·
IF 9.7
Yidi Wang,Yang Wang,Ziqi Wang,Liangfeng Luo,Benjamin Tawiah,Chang Liu,Jiachuan Hua,Yang Ming,John H. Xin,Wai-Yeung Wong,Bin Fei
While the metal halide perovskite materials are emerging as potentially promising photocatalysts, they still suffer from the intrinsic instability, seriously hampering their further practical applications. In this study, a perovskite-based composite with a sandwich structure is first established to realize the encapsulation of individual octylamine-capped MAPbBr 3 (OM-PE) quantum dots (QDs), and the Zeolitic Imidazolate Framework-67 (ZIF-67) isolates the individual OM-PE@PbBrOH QDs (2 nm) to preserve their unique optoelectronic properties while preventing degradation from environmental factors. The resulting sandwich composite was proved to be a staggered-gap heterostructure with a p–n junction, in which the PbBrOH layer acted as a water-resisting covering and ZIF-67 layer promoted the electron mobility. Benefiting from the chemical interactions and interfacial charge dynamics among the different layers, the OM-PE@PbBrOH ⊂ ZIF-67 composite exhibited the superior stability in water for two months, and presented an enhanced photodegradation efficiency of organic dyes (malachite green, methylene blue and rhodamine B), which is around 24 times higher than that of pristine perovskite. By integrating the respective merits of each component, this work unprecedentedly constructs the 2 nm sandwich-like OM-PE@PbBrOH ⊂ ZIF-67 composite, and opens new avenues for stable, efficient, and multifunctional photocatalytic systems, with potential applications beyond wastewater treatment.
研究领域:
材料科学
·
环境科学
·
纳米技术
·
光催化
·
无机化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
LANGMUIR
·
2020
·
IF 3.557
Jincheng Li,Jialei Zhang,Zengchao Guo,Hui Jiang,Haijun Zhang,Xuemei Wang
Magnetic–fluorescent nanocomposites have a tremendous potential in biomedicine realms as a revolutionary dual-modality probe tool for more accurate medical detection. However, complicated and inefficient postprocesses pose obstacles to obtaining high-quality magnetic–fluorescent nanocomposites. Thus, the fabrication of magnetic–fluorescent functional nanocomposites via a simple, effective, and ideal method remains a challenge and is still waiting to be tapped. The new synthesis approaches are becoming impending demands and probably enable us to address these above-mentioned problems. In this contribution, we present a novel self-assembly synthesis route for the construction of magnetic–fluorescent bimodal imaging nanocomposites rather than adopting sophisticated postpreparative processes. The Fe3O4 and quatum dots (QDs) nanocomposites were cross-linked fleetly by cerium(III) ion driven coordination bonds in which the cerium(III) ions served as the cross-connecting node and the carboxylate groups acted as bridging ligands. The potential application for dual-modality imaging capability was validated on tumor-bearing mice. This ingenious strategy was extremely efficient and handy for the magnetic–fluorescent Fe3O4–QDs nanocomposite construction. Significantly, our cerium(III) ion driven self-assembly method probably has a wide applicability for nanoparticles and organic molecules containing carboxyl groups but extensive explorations are still necessary.
研究领域:
纳米技术
·
生物医学工程
·
材料科学
·
成像技术
✓ 已验证
DOI
PubMed
高影响因子
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
·
2013
·Vol. 15
·期 37
·15660-15668
·
IF 3.829
Jungang Hou,Chao Yang,Huijie Cheng,Zheng Wang,Shuqiang Jiao,Hongmin Zhu
Highly efficient hydrogen production can be achieved by three-dimensional (3D) architectures of CdS quantum dots (QDs) incorporated in the porous assembly of marigold-like ZnIn2S4 heterostructures coupled with graphene, leading to an efficient electron transfer between them and the enhancement of the ZnIn2S4 photostability. The as-prepared samples were characterized by X-ray diffraction, electron microscopy, Brunauer–Emmett–Teller analysis, X-ray photoelectron spectroscopy, UV-vis diffuse reflectance absorption spectra, and photoluminescence spectra. Especially, 3 wt% CdS QDs decorated ZnIn2S4 heteroarchitectures showed a high rate of H2-production at 1.9 mmol h−1, more 2.7 times than that of ZnIn2S4. The rate was further increased to 2.7 mmol h−1 with a high quantum efficiency of 56% using the 3 wt% CdS QDs decorated ZnIn2S4 composites coupled with 1 wt% graphene (about 4 times higher than that of the pure ZnIn2S4). Moreover, the CdS QDs/graphene/ZnIn2S4 exhibited strong durability due to the high hydrothermal stability of the flower-like structure and the inhibition of CdS leaching owing to its strong interaction with ZnIn2S4. The excellent photocatalytic performance is ascribed to the enhanced light absorption and the improved separation of photogenerated carriers. This finding highlights the validity of 3D semiconductor heterostructures as effective building blocks for exploring efficient visible-light-active photocatalysts.
研究领域:
材料科学
·
光催化
·
纳米材料
·
能源化学
·
半导体物理
✓ 已验证
DOI
高影响因子
PHOTOCHEMISTRY AND PHOTOBIOLOGY
·
2025
·
IF 2.5
Yao Zhang,Shiming Zhang,Li Luo,Sansan Hu,Xujuan Huang,Yongzheng Chen
Using visible light to drive NADH regeneration is an economically viable and environmentally sustainable technique. However, it necessitates a metal hydride (MH, [CpRh(bpy)(H 2 O)] 2+ ) as a synergist, and the high cost of the Rh noble metal significantly impedes the development and application of in-situ NADH regeneration. Therefore, in this study, single-atom Rh was immobilized onto the CdS QDs@SiO 2 combination via a consecutive ball-milling technique in combination with ionic layer adsorption and substitution. Subsequently, an enhanced photo-metal synergistic catalysis system for the recyclable regeneration of NADH was developed. In this composite, the single-atom Rh serves two main functions: It acts as an electrical medium and a metal catalyst, which regulates the activity and selectivity of the regenerated NADH. This study has successfully addressed the key scientific issues regarding the low electron transport rate and the recycling of the Rh noble metal during catalysis. Results confirm that single-atom Rh is successfully immobilized onto the CdS QDs@SiO 2 combination (Rh-CdS@SiO 2 ) and exhibits a faster electron transport and enhanced selectivity. Under blue light (LED, 420 nm) irradiation, the Rh-CdS@SiO 2 photo-metal catalyst shows a 25-fold increase in recyclable operability and achieves a 68% regeneration yield of NADH in just 4 min. Moreover, (S)-(+)-4-phenyl-2-butanol can be obtained with the regenerated NADH as the coenzyme of P450 enzyme catalysis.
✓ 已验证
DOI
高影响因子
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
·
2021
·
IF 8.067
Bo Yu,Fei Ma,Dongjiang Chen,Katam Srinivas,Xiaojuan Zhang,Xinqiang Wang,Bin Wang,Wanli Zhang,Zegao Wang,Weidong He,Yuanfu Chen
The shuttle effect of lithium polysulfides (LiPSs) and sluggish redox conversion significantly hinder practical implementation of lithium-sulfur batteries (LSBs). To overcome these issues, herein, we present MoP quantum dots anchored N, P-doped graphene (MPQ@G) as a multifunctional LSB cathode. The N, P-doped graphene layers serve as a conductive skeleton to support the MoP QDs which can accelerate the electron transfer, physically hinder the polysulfide migration and thus enhance the electrochemical performance. More importantly, as a polar and conductive catalyst, MoP QDs provide catalytically active sites for the conversion of LiPSs. As a result, the LSBs with MPQ@G/S cathodes deliver an elevated initial capacity of 1220.2 mAh g −1 at 0.2 C and remain 98.9% after rate cycles, signifying its exceptional cycling stability. Moreover, it displays a large capacity of 681.2 mAh g −1 even at a high rate of 1 C. The Li-S pouch cell also presents high specific capacities and preeminent cycling stabilities, confirming its great potential for high-rate applications. Density functional theory calculations demonstrate the improved absorptivity and redox conversion reversibility of LiPSs. This work provides an efficient strategy to improve composite with highly adsorptive and catalytic properties for high-performance Li-S batteries.
研究领域:
材料科学
·
电化学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）