Journal of Physical Chemistry C
·
2015
·
IF 4.772
Xianying Zheng,Jixi Zhang,Jie Wang,Xueqiang Qi,Jessica M. Rosenholm,Kaiyong Cai
A composite nanocarrier system integrating the porous structure of mesoporous silica nanoparticles (MSNs) and the adhesive property of polydopamine (PDA) for loading and release of hydrophilic drugs is reported. Amino group functionalization facilitates the oxidant-induced surface polymerization of dopamine in the confined space of mesopores by Schiff base/Michael addition reaction in a mild synthesis. As a consequence, MSN@PDA particles have an average pore size of 4.0 nm, a particle diameter of ∼70 nm, as well as a thin layer of polydopamine coating on the surfaces of MSNs. The MSN@PDA nanocarriers can effectively adsorb hydrophilic drugs with high loading capacities (380 μg/mg for doxorubicin hydrochloride (DOX) and 320 μg/mg for calcein), facilitated by the π–π stacking interactions between the abundant aromatic rings of PDA and the aromatic backbones of drugs. Interestingly, sustained and pH-dependent drug release was observed for these drug-loaded MSN@PDA particles, owing to the adhesive property of polydopamine like “molecular glue”. Moreover, a catechol–metal–drug coordination system can be easily constructed on the basis of the coordination bonding between catechols in polydopamine and transition metal ions (Fe3+, Zn2+) as well as that between metal ions and anthracycline drugs (i.e., DOX), resulting in an acid-triggered drug release.
研究领域:
药剂学
·
纳米医学
·
生物材料
·
药物递送系统
·
肿瘤治疗
·
分子影像
·
化学生物学
✓ 已验证
DOI
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2026
·
IF 8.8
Weiyao Han,Huiting Zhang,Shuo Li,Jia-Li Hu,Ming-Jie Yin,Quan-Fu An
Mixed-matrix membranes (MMMs), which combine the flexible processability of polymers with the high mass-transfer capabilities of porous fillers such as metal-organic frameworks (MOFs), are widely regarded as next-generation, high-performance materials for CO 2 capture. However, challenges such as MOF aggregation and poor interfacial compatibility between MOFs and polymers often result in membrane defects, ultimately reducing CO 2 /N 2 selectivity. To address this issue, we propose an in situ MOF crystallization strategy within confined spaces to construct defect-free MMMs for CO 2 separation. In this method, prepolymers and MOF precursors are molecularly dissolved in a solvent. Following UV-induced crosslinking of the prepolymers, a gel membrane is formed, providing a confined environment for in situ MOF crystallization. The high degree of crosslinking ensures a uniform distribution of MOF nanoparticles and limits their size. This uniformity enhances interfacial interactions and effectively suppresses the formation of interfacial defects. The optimized membrane exhibited a simultaneous increase in both CO 2 permeability and CO 2 /N 2 selectivity, a 17.5-fold and 26% enhancement, respectively, compared with the pristine polymer membrane. Furthermore, due to its strong interfacial structure, the membrane demonstrated excellent mechanical stability under applied pressure and maintained consistent performance over 200 h of continuous operation. This method offers a novel and effective approach for fabricating uniform, defect-free MMMs for advanced CO 2 separation applications.
✓ 已验证
产品关联
DOI
高影响因子
CARBON
·
2021
·
IF 9.594
Zijin Yang,Xianying Qin,Kui Lin,Qiuchan Cai,Cuiping Han,Feiyu Kang,Baohua Li
Tin dioxide (SnO 2 ) is a promising anode material for lithium-ion and sodium-ion batteries. However, the huge volume expansion during cycling makes it far away from practical application. Herein, we report a template-free “heterogeneous carbonization” strategy for fabricating SnO 2 /carbon/void/carbon nanofibers (SCVC) compound membrane with finite spatial domain in carbon matrix as buffer layer for volume changes of SnO 2 . Reduced graphene oxide (rGO) is also imported into the SCVC membrane, acting as conductive binders to construct a free-standing SCVC-rGO electrode with exceptionally conductive network. The resultant SCVC-rGO anodes in lithium/sodium-ion batteries could deliver excellent electrochemical performances of higher reversible capacity, longer lifespan and superior rate capability. As lithium-ion battery anode, the SCVC-rGO electrode shows specific capacities of 950 mA h g −1 after 400 cycles at a current of 0.5 A g −1 , and 824 mA h g −1 after 650 cycles at 1 A g −1 . In sodium-ion batteries, the SCVC-rGO electrode gives rise to the specific capacity of 407 mA h g −1 after 2000 cycles at the current of 1 A g −1 with exceptional capacity retention.
研究领域:
材料科学
·
电化学
·
能源存储
✓ 已验证
DOI
高影响因子
CRYSTAL GROWTH & DESIGN
·
2017
·
IF 4.055
Meng Pan,Jiajun Zheng,Yujian Liu,Qinglan Kong,Huiping Tian,Ruifeng Li
Hollow zeolite microspheres have attracted considerable interest due to their unique properties and great potential applications. In this work, we report a simple and cost-effective approach for constructing hollow zeolite microspheres based on a biomass-derived template, i.e., carboxymethylcellulose sodium (CMC). As an example, a hollow ZSM-5 microsphere with a hollow core smaller than 1 μm in diameter and a complete crystal shell is synthesized. This approach overcomes most of the limitations associated with the existing methods, such as complex operations and costly spherical templates. By studying the growth process in detail, a possible formation mechanism is proposed. The crystallization of the hollow zeolite microsphere is through a “surface to core” process, in which the interaction between the CMC and the zeolite gel and the decomposition of the polymer network play the critical roles.
研究领域:
材料科学
·
化学工程
✓ 已验证
DOI
高影响因子
Advanced Materials Technologies
·
2022
·Vol. 7
·期 9
·2101544
·
IF 8.856
Longwei Ke,Jinhua Liu,Yunfeng Hu,Xiaomin Zhang,Xiaopei Zhang,Yisha Wang,Yan Luo,Wenqing Wang,Yan Yan,Huijuan Lin,Kun Rui,Jixin Zhu,Yi Zhu
Wearable electronic devices have received much attention for their potential applications in soft robotics, human-machine interaction, and human motion detection. Herein, a high-performance wearable fiber sensor is constructed for monitoring human micromotion by enabling compressive space dynamics manipulation. The developed sensor depends on the porous microstructure of vanadium pentoxide@ reduced graphene oxide fiber and endows it high sensitivity in sensing. Importantly, the sensor still presents a similar porous structure compared with the initial state even after thousands of repeated bending-releasing cycles, ensuring a long-term stability. Furthermore, the synergistic effect of multiple fibers can broaden the detection range and further improve the sensitivity. Consequently, the assembled multi-fiber sensor exhibits a high sensitivity (a gauge factor value of 245.1) and an excellent stability (4000 cycles). Finally, these sensors are successfully applied to monitor small-scale human movements, showing tremendous potential as wearable electronics.
研究领域:
可穿戴电子学
·
柔性传感器
·
人机交互
·
软体机器人
·
运动检测
✓ 已验证
DOI
高影响因子
XENOTRANSPLANTATION
·
2022
·Vol. 30
·期 1
·e12787
·
IF 3.788
Zhen Geng,Qi Zhang,Ting Li,Ting Huang,Hailian Wang,Qiao Zhou,Shaoping Deng,Yanshuang Zhao,Yanjiao Li,Chunming Cheng,Carmen Gonelle-Gispert,Leo H. Buhler,Yi Wang
Objective Islet allotransplantation has demonstrated improved clinical outcomes using the hepatic portal vein as the standard infusion method. However, the current implantation site is not ideal due to the short-term thrombotic and long-term immune destruction. Meanwhile, the shortage of human organ donors further limits its application. To find a new strategy, we tested a new polymer combination for islet encapsulation and transplantation. Meanwhile, we explored a new site for xenogeneic islet transplantation in mice. Method We synthesized a hydrogel combining alginate plus poly-ethylene-imine (Alg/PEI) for the encapsulation of rat, neonatal porcine, and human islets. Transplantation was performed into the retroperitoneal retro-colic space of diabetic mice. Control mice received free islets under the kidney capsule or encapsulated islets into the peritoneum. The biochemical indexes were measured, and the transplanted islets were harvested for immunohistochemical staining of insulin and glucagon. Results Mice receiving encapsulated rat, porcine and human islets transplanted into the retroperitoneal space maintained normoglycemia for a median of 275, 145.5, and 146 days, respectively. In contrast, encapsulated xenogeneic islets transplanted into the peritoneum, maintained function for a median of 61, 95.5, and 82 days, respectively. Meanwhile, xenogeneic islets transplanted free into the kidney capsule lost their function within 3 days after transplantation. Immunohistochemical staining of encapsulated rat, porcine and human islets, retrieved from the retroperitoneal space, allowed to distinguish morphological normal insulin expressing β- and glucagon expressing α-cells at 70, 60, and 100 days post-transplant, respectively. Conclusion Transplantation of Alg/PEI encapsulated xenogeneic islets into the retroperitoneal space provides a valuable new implantation strategy for the treatment of type 1 diabetes.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Materials Today Physics
·
2023
·
IF 11.5
Rahul A. Rajan,Huang Tao,Weili Yu,Jianjun Yang
Femtosecond laser processing of lead halide perovskites has recently sparked wide popularity for creating various micro/nanostructures and instigating interesting properties. However, it is still lacking detailed insights into correlating the laser induced morphology and defect chemistry of perovskite materials to their light emitting properties. Here, the space-resolved photoluminescence and lasing behaviors are investigated for both the single crystal (SC) and polycrystalline (PC) perovskites upon femtosecond laser ablation . In the case of SC sample, three different regions based on the laser ablation , recast deposition, and modification respectively exhibits distinguished carrier recombination mechanisms due to their variable defect chemistries and morphologies identified, which helps to realize the amplified spontaneous emission with the recrystallized micro/nanostructures. On the other hand, the laser modified region on the PC sample reveals the significant enhancement of random lasing performance (the lasing threshold was reduced by ∼7 times and the slope efficiency increased by ∼1.5 times), which is attributed to the femtosecond laser induced non-radiative defect passivation and the average crystalline grain size reduction by more than 1.5 times. This study unveils the physical and chemical modification effects of the femtosecond laser irradiation on perovskite materials, and thus is an optimal strategy to fabricate desired perovskite light-emitting microstructures by ultrafast laser processing.
✓ 已验证
产品关联
DOI
高影响因子
Solar RRL
·
2023
·Vol. 7
·期 7
·2201093
·
IF 7.9
Xiaohong Ma,Danyang Li,Jun Xie,Jian Qi,Huacheng Jin,Liuyang Bai,Hao Zhang,Feifei You,Fangli Yuan
The reduction of CO 2 to chemical fuel driven by solar energy can not only meet the growing demand for renewable energy, but also balance the carbon cycle in nature. However, the current photocatalysts have low CO 2 conversion due to their poor light capture ability, narrow light response range, and high recombination probability of photogenerated carriers. Herein, a heterogeneous photocatalyst of hollow structured ZnO/ZnS decorated with Pt nanoparticles is synthesized through the hydrothermal process and photodeposition method, showing excellent photocatalytic activity for CO 2 reduction in long-time stability and ≈100% CO selectivity, which can mainly contribute to natural enhanced light-capture ability of the hollow confined space due to multiple reflection and scattering of light in the cavity, thus improving separation efficiency of photogenerated charge carriers due to the type II junction constructed between ZnO and ZnS and the additional reaction active sites after decorating Pt nanoparticles in the surface of the hollow structure.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
·
2023
·Vol. 106
·期 12
·7503-7513
·
IF 3.9
Mengmeng Zhu,Yunpeng Liu,Haojie Ding,Shulan Zhang,Mujing Qu,Tongtong Xuan,Huili Li
All-inorganic CsPbX 3 (X = Cl, Br, and I) perovskite nanocrystals (NCs) have great application prospects in many fields due to their excellent photoelectric properties. However, CsPbX 3 NCs are extremely sensitive to water, heat, light, and oxygen, which leads to dramatic photoluminescence quenching and seriously restricts their future commercial applications. Herein, a novel, simple one-step solution strategy for synthesizing high-quality CsPbBr 3 NCs was reported. By the combination of the hot-injection process with the mesoporous template confinement effect of the KIT-6 matrix, the space-confined growth of NCs was precisely achieved. The CsPbBr 3 NCs encapsulated by KIT-6 (CsPbBr 3 @KIT-6 composite) exhibited a uniform size, a high photoluminescence quantum yield (PLQY) of up to 82%, and a narrow full width at half-maximum (FWHM) of 24 nm. Most importantly, CsPbBr 3 @KIT-6 powder composites had dramatically enhanced light, thermal and water stability in comparison with colloidal CsPbBr 3 NCs due to the dual protection of organic ligands and matrix templates. Ultimately, a white light-emitting diode (LED) device was successfully fabricated by encapsulating a mixture of green-emitting CsPbBr 3 @KIT-6 composite and red-emitting K 2 SiF 6 :Mn 4+ phosphor onto a blue-emitting InGaN LED chip. A color coordinate of (0.327, 0.337) and a wide color gamut of 128% NTSC well demonstrate their potential applications in lighting and display.
✓ 已验证
产品关联
DOI
高影响因子
Pharmaceuticals
·
2022
·Vol. 15
·期 11
·1394
·
IF 5.215
Tingting Li,Dong Han,Zhongxian Li,Mengqi Qiu,Yuting Zhu,Kai Li,Jiawei Xiang,Huizhen Sun,Yahong Shi,Tun Yan,Xiaoli Shi,Qiang Zhang
Idiopathic pulmonary fibrosis is a fatal interstitial disease characterized by fibroblast proliferation and differentiation and abnormal accumulation of extracellular matrix, with high mortality and an increasing annual incidence. Since few drugs are available for the treatment of pulmonary fibrosis, there is an urgent need for high-efficiency therapeutic drugs and treatment methods to reduce the mortality associated with pulmonary fibrosis. The interstitium, a highly efficient transportation system that pervades the body, plays an important role in the occurrence and development of disease, and can be used as a new route for disease diagnosis and treatment. In this study, we evaluated the administration of hydroxysafflor yellow A phytosomes via intervaginal space injection (ISI) as an anti-pulmonary fibrosis treatment. Our results show that this therapeutic strategy blocked the activation of p38 protein in the MAPK-p38 signaling pathway and inhibited the expression of Smad3 protein in the TGF-β/Smad signaling pathway, thereby reducing secretion of related inflammatory factors, deposition of collagen in the lungs of mice, and destruction of the alveolar structure. Use of ISI in the treatment of pulmonary fibrosis provides a potential novel therapeutic modality for the disease.Keywords:intervaginal space injection;pulmonary fibrosis;hydroxysafflor yellow A;phytosome;interstitial treatment
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CARBON
·
2022
·
IF 11.307
Yongqian Shen,Fan Zhang,Yuchen Zhang,Pengfei Song,Feng Gao,Dong Zhang,Chunli Liu,Jiqiang Ma,Huixia Feng,Xueyan Du
Advanced microwave absorbers (MAs) containing magnetic particles and carbon nanofibers (CNFs) have raised widespread attention in the rapid popularization of electronic communication equipment. However, it is quite challenging to control the growth of magnetic particles in CNFs to improve electromagnetic waves (EMWs) loss and attenuation. Herein, a novel space-confined strategy was adopted to develop Co/CoO/SiO 2 /CNFs, in which Co/CoO nanoparticles (NPs) with single domain size and dispersed distribution could achieve enhanced magnetic loss and dielectric loss. The introduction of nano-SiO 2 in the system could enhance the dielectric confinement effect of the nanofibers (NFs), while an interfacial confinement network could also be constructed to realize the refinement of Co/CoO NPs, enhance the electromagnetic (EM) loss, and ultimately ameliorate the microwave absorption performance of as-obtained NFs. When the additive amount of nano-SiO 2 in the spinning solution was 1.0 mg, the as-prepared Co/CoO/SiO 2 /CNFs reached the optimal reflection loss (RL) of −52.9 dB at 12.64 GHz with a thickness of 2.5 mm, and the effective bandwidth (EBW) reached 5.67 GHz (10.46–16.13 GHz). Furthermore, the excellent hydrophobic properties of the CNFs endow them with potential self-cleaning function. The confinement strategy proposed in this work lays a foundation for the design of low-filling ratio and high-performance CNFs-based microwave absorbers, and presents a general approach for the synthesis of one-dimensional composite materials with controllable structures.
✓ 已验证
产品关联
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2022
·
IF 7.392
Yang Li,Wenjing Wei,Jiaqi Chen,Lijie Zu,Yan Zhou,Jinzhu Wu,Xiaohong Wu
In spaceflight applications, molecular contamination control has become one of the most challenging issues. Porous zeolites are a potent molecular adsorbent with advantages of efficient adsorption at low pressure and/or high temperature, high interaction with adsorbates, and superior durability in extreme environments. Herein, zeolite 13X pellets were selected for adsorption of stearyl alcohol (C 18 H 37 OH) as a target molecular contaminant. Considering the excellent hydrophilicity of the zeolite 13X which limits the adsorption of most hydrophobic organic molecules, modification of the zeolite 13X by deposition of TiO 2 via atomic layer deposition (ALD) technology was performed. Results show that ALD-grown TiO 2 not only improves hydrophobicity but also renders high activity, whilst retains the hierarchical pores of the zeolites. As a result, the as-prepared zeolite 13X@TiO 2 exhibits efficient adsorption toward trace stearyl alcohol under low pressure through the synergistic contribution of physisorption and chemisorption. Monte Carlo (MC) simulation, molecular dynamic (MD) and Density Functional Theory (DFT) calculations further discover that pore wall surfaces are primary adsorption sites for the physisorption while ALD-grown TiO 2 provides active sites for the chemisorption.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）