CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Zhengren Tao,Fangrui Cheng,Yinghan Wang,Sijie Su,Enhai Song,Jiulin Gan,Shi Ye
The arrangement of lithium and niobium in the LiNbO 3 lattice is crucial to its notable ferroelectric, piezoelectric, ion conductive, and nonlinear optical properties. However, the synthesis of Li concentration-gradient nanocrystals remains a significant challenge. In this paper, we report a reliable method for synthesizing LiNbO 3 : Yb/Er nanocrystals with a Li-gradient through topochemical molten salt synthesis. We elucidate the Li-gradient characteristics using various analytical techniques, including depth-dependent elemental analysis. Variable-temperature upconversion luminescence spectroscopy provided insights into thermally induced surface and interior Li + diffusion. Our findings demonstrate that Li-gradient nanocrystals exhibit enhanced ferroelectric behavior and increased sensitivity to mechanical force in upconversion emission response. This study proposes a feasible universal strategy for synthesizing alkali metal niobate materials with controlled polarization, offering promising candidates for flexible, low-power optoelectronic devices.
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POWDER TECHNOLOGY
·
2012
·
IF 2.08
Wanyue Shao,Ruinian Hua,Wei Zhang,Yue Tian,Jun Zhao,Liyan Na,Jicheng Yu,Zhengang Sun
Carboxylic acid-functionalized Yb 3 + /Er 3 + co-doped α - and β -NaYF 4 nano-/micro-spheres were prepared through a simple poly(acrylic acid) (PAA)-assisted hydrothermal process. Bovine serum albumin (BSA) protein was conjugated with Yb 3 + /Er 3 + co-doped α -( β -)NaYF 4 upconversion phosphors via free carboxylic acid groups on the surface of phosphors. The final products were characterized by X-ray diffraction (XRD), field emission scanning electron microscopy (FE-SEM), infrared (IR) spectrophotometer, ultraviolet (UV) spectrophotometer and photoluminescence spectroscopy (PL). XRD results showed that pure α -NaYF 4 :Yb 3 + , Er 3 + nanospheres could be obtained via PAA assisted hydrothermal process at the pH value of 4–5 and 160 °C for 1–4 h. The obtained product is a mixture of α and β phases NaYF 4 :Yb 3 + , Er 3 + when the reaction time increased from 5 to 24 h. When the solution was treated at 200 °C for 8–24 h at the pH value of 8–9, pure β -NaYF 4 :Yb 3 + , Er 3 + microspheres were obtained. The FE-SEM results showed that the morphology of pure α -NaYF 4 :Yb 3 + , Er 3 + was spherical nanoparticles with an average diameter of about 70 nm and the pure β -NaYF 4 :Yb 3 + , Er 3 + was microsphere with an average diameter of about 700 nm, which is composed of spherical nanoparticles (30 nm). The FT-IR and UV spectra showed that BSA had been conjugated with α -NaYF 4 :Yb 3 + , Er 3 + upconversion phosphors. The luminescence properties of α -( β -) NaYF 4 :Yb 3 + , Er 3 + phosphors were also studied. Under 980 nm excitation, the upconversion luminescence (UCL) intensity of β -NaYF 4 :Yb 3 + , Er 3 + microspheres was much stronger than that of α - NaYF 4 :Yb 3 + , Er 3 + nanoparticles. Moreover, both red and green upconversion were ascribed to the two-photon process.
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Nanoscale
·
2015
·Vol. 8
·期 2
·1040-1048
·
IF 7.394
Xiaojuan Huang,Bo Li,Chen Peng,Guosheng Song,Yuxuan Peng,Zhiyin Xiao,Xijian Liu,Jianmao Yang,Li Yu,Junqing Hu
Imaging guided photothermal agents have attracted great attention for accurate diagnosis and treatment of tumors. Herein, multifunctional NaYF4:Yb/Er@polypyrrole (PPy) core–shell nanoplates are developed by combining a thermal decomposition reaction and a chemical oxidative polymerization reaction. Within such a composite nanomaterial, the core of the NaYF4:Yb/Er nanoplate can serve as an efficient nanoprobe for upconversion luminescence (UCL)/X-ray computed tomography (CT) dual-modal imaging, the shell of the PPy shows strong near infrared (NIR) region absorption and makes it effective in photothermal ablation of cancer cells and infrared thermal imaging in vivo. Thus, this platform can be simultaneously used for cancer diagnosis and photothermal therapy, and compensates for the deficiencies of individual imaging modalities and satisfies the higher requirements on the efficiency and accuracy for diagnosis and therapy of cancer. The results further provide some insight into the exploration of multifunctional nanocomposites in the photothermal theragnosis therapy of cancers.
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PubMed
高影响因子
JOURNAL OF TOXICOLOGICAL SCIENCES
·
2019
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IF 1.732
Yuan Chen,Xiaoxiao Fei,Chenqiao Ye,Qinqing Qian,Zhiqiu Ye,Siqi Xie,Jiamin Chen,Mingliao Zhu,Na Ran,Mingsheng Hou,Lin Xu,Zhangsen Yu
In the past few decades, upconversion nanoparticles (abbreviated as UCNPs) have been more widely applied in the biomedical fields, such as in vitro and in vivo upconversion fluorescent bioimaging, photodynamic therapy, biological macromolecular detection, imaging mediated drug delivery and so on. But meanwhile, there is still not much research on the acute toxicity of upconversion nanoparticles in vivo, such as acute hepatotoxicity. In this work, we studied the in vivo biodistribution and acute hepatotoxicity of multimodal targeted contrast agent NaLuF4:Gd,Yb,Er-PEG/PEI-FA nanoprobe, which were synthesized by the solvothermal method and modified with Polyethylene glycol (PEG), Polyetherimide (PEI), folic acid (FA) on the surface. The acute hepatotoxicity in mice was systematically assessed after tail vein injection of different concentration of UCNPs. The results showed that NaLuF4:Gd,Yb,Er-PEG/PEI-FA nanoparticles with an average diameter of 44.5 ± 10.4 nm, and three typical upconversion fluorescence emission bands at 520 nm, 540 nm and 660 nm under the excitation of 980 nm laser. In vivo distribution experiments results demonstrated that approximately 87% of UCNPs injected through the tail vein accumulate in the liver. In the acute hepatotoxicity test, the intravenously injection dose of UCNPs was 10, 40, 70 and 100 mg/kg, respectively. The body weight, blood routine, serum biochemistry, histomorphology and liver oxidative stress were detected and observed no significant acute hepatotoxicity damage under the injection dose of 100 mg/kg. In conclusion, NaLuF4:Gd,Yb,Er-PEG/PEI-FA nanoprobes are safe and reliable, and have potential applications in the field of tumor targeted multimodal imaging.
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高影响因子
Journal of Nanomaterials
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2012
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IF 1.376
Suli Wu,Yanhui Ning,Shufen Zhang
Novel chelating ligands are very significant for preparing nanocrystals with different morphologies and applications. In this paper, we directly introduced amine groups onto UCNPs by choosing a new chelating ligand tetraethylene pentamine (TEPA) to synthesis
N
a
Y
F
4
:Yb, Er through hydrothermal method. The influences of rare earth concentration, the ratio of RE/TEPA, solvent composition, and reaction time on the morphology and fluorescence intensity of the as-prepared
N
a
Y
F
4
:Yb, Er samples were systematically investigated and discussed. Field emission scanning electron microscopy (FE-SEM), powder X-ray diffraction (XRD), and upconversion luminescence spectroscopy were used to characterize the product. It was found that rare earth concentration, ratio of RE/TEPA, solvent composition, and reaction time were all responsible for the luminescent intensity and morphology.
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OPTICAL MATERIALS
·
2025
·
IF 4.2
Haoran Zhang,Tianxi Feng,Song Ye,Deping Wang
In this research, the modified upconversion nanocrystals NaYF 4 :Yb,Er were adopted as the precursors for the synthesis of the NaYF 4 :Yb,Er@UiO-66 composite. The XRD, XPS and TEM characterizations indicated that the composite has good crystallinity and uniform morphology. Under 980 nm excitation, the NaYF 4 :Yb,Er@UiO-66 composite exhibits bright upconversion emission that characterized of Er 3+ : 2 H 11/2 → 4 I 15/2 , 4 S 3/2 → 4 I 15/2 , and 4 F 9/2 → 4 I 15/2 radiative transitions. After modified with BPEI (branched polyethyleneimine), the NaYF 4 :Yb,Er@UiO-66/BPEI fluorescence probe was constructed and was used for the detection of Cu 2+ . The results revealed that the integrated emission intensity of Er 3+ displayed a linear relationship with the concentration of Cu 2+ within the range of 5 to 45 μM with a LOD of 0.9615 μM. This study offered a feasible method for constructing UCNC@UiO-66 composites with regular morphology,which may have a potential application as fluorescent probes for the detection of various metal ions by adjusting the doping luminescent center.
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Scientific Reports
·
2017
·Vol. 7
·期 1
·1-8
·
IF 4.259
Chen Xu,Zhou Donglei,Xu Wen,Zhu Jinyang,Pan Gencai,Yin Ze,Wang He,Zhu Yongsheng,Shaobo Cui,Song Hongwei
Localized electric filed enhancement by surface plasmon resonance (SPR) of noble metal nanoparticles is an effective method to amplify the upconversion luminescence (UCL) strength of upconversion nanoparticles (UCNPs), whereas the highly effective UCL enhancement of UCNPs in colloids has not been realized until now. Here, we designed and fabricated the colloidal Au-Ag nanocage@NaYF 4 @NaYF 4 :Yb,Er core-shell hybrid with different intermediate thickness (NaYF 4 ) and tunable SPR peaks from visible wavelength region to NIR region. After the optimization of the intermediate spacer thickness (~7.5 nm) of NaYF 4 NPs and the SPR peak (~950 nm) of noble metal nanoparticles, an optimum enhancement as high as ~25 folds was obtained. Systematic investigation indicates that UCL enhancement mainly originates from the influence of the intermediate spacer and the coupling of Au-Ag nanocages with the excitation electromagnetic field of the UCNPs. Our findings may provide a new thinking on designing highly effective metal@UCNPs core-shell hybrid in colloids.
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Nature Communications
·
2022
·Vol. 13
·期 1
·1-11
·
IF 17.694
Liao Jinsheng,Wang Minghua,Lin Fulin,Han Zhuo,Fu Biao,Tu Datao,Chen Xueyuan,Qiu Bao,Wen He-Rui
Rare earth (RE 3+ )-doped phosphors generally suffer from thermal quenching, in which their photoluminescence (PL) intensities decrease at high temperatures. Herein, we report a class of unique two-dimensional negative-thermal-expansion phosphor of Sc 2 (MoO 4 ) 3 :Yb/Er. By virtue of the reduced distances between sensitizers and emitters as well as confined energy migration with increasing the temperature, a 45-fold enhancement of green upconversion (UC) luminescence and a 450-fold enhancement of near-infrared downshifting (DS) luminescence of Er 3+ are achieved upon raising the temperature from 298 to 773 K. The thermally boosted UC and DS luminescence mechanism is systematically investigated through in situ temperature-dependent Raman spectroscopy, synchrotron X-ray diffraction and PL dynamics. Moreover, the luminescence lifetime of 4 I 13/2 of Er 3+ in Sc 2 (MoO 4 ) 3 :Yb/Er displays a strong temperature dependence, enabling luminescence thermometry with the highest relative sensitivity of 12.3%/K at 298 K and low temperature uncertainty of 0.11 K at 623 K. These findings may gain a vital insight into the design of negative-thermal-expansion RE 3+ -doped phosphors for versatile applications.
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OPTICAL MATERIALS
·
2020
·
IF 2.779
Hua Li,Xiaobo Shi,Xia Li,Lingbo Zong
Size-tunable β-NaYF 4 : Yb/Er (50–400 nm) up-converting nanoparticles (UCNPs) with a strong green emission were successfully prepared by a facile thermal decomposition method in a short period of time. The effects of the reaction time, the oleic acid (OA) content, and the doped Gd 3+ concentration on the crystal structure, the size evolution mechanism and the luminescence mechanism of the β-NaYF 4 : Yb/Er nanoparticles were discussed in detail. Characterization was completed using X-ray diffraction (XRD), transmission electron microscopy (TEM), high-resolution (HR-TEM), scanning electron microscopy (SEM), and photoluminescence (PL). The results reveal that the phase transition was completed at 15 min and the morphology of the NaYF 4 : Yb/Er UCNPs changed from spherical to large hexagonal disks (200–400 nm) in non-doped Gd 3+ . An appropriate decrease in the volume ratio of oleic acid (OA) to 1-octadecene (ODE) promoted NaF production, resulting in the formation of the hexagonal phase crystals and the subsequent increase of luminous intensity by 30–40 times. More importantly, the size of the β-NaYF 4 : Yb/Er decreased with Gd 3+ doping, and the UCNPs ultimately transformed into small hexagonal prisms (50 nm) with high monodispersity when the doping concentration of Gd 3+ was 60 mmoL. The PL spectra confirmed that the luminous intensity of the UCNPs with doped Gd 3+ was much higher than that of the undoped UCNPs. The results show that this route for UCNP fabrication with high luminous efficiency and a small size could be extended to other UCNP systems for multifunctional biomedical applications.
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高影响因子
BIOSENSORS & BIOELECTRONICS
·
2015
·
IF 6.409
Jianguo Zhang,Shaozhen Wang,Ni Gao,Dexiang Feng,Lun Wang,Hongqi Chen
A new turn-on luminescence energy transfer (LET) system has been designed for the detection of prostate specific antigen (PSA, a cancer marker) that utilizes Mn 2+ -enhanced long wavelength luminescence NaYF 4 : Yb, Er upconversion nanorods as the donor and gold nanorods as the acceptor. The Mn 2+ -doped NaYF 4 :Yb,Er upconversion luminescence nanorods with an emission peak located in the red region were synthesized. The presence of Mn 2+ markedly increased the luminescence intensity over that of the NaYF 4 :Yb, Er upconversion nanomaterials (excited by a 980 nm continuous wavelength laser). The surfaces of Mn 2+ -doped NaYF 4 :Yb, Er upconversion nanorods were modified with poly(acrylic acid). Antibodies against prostate specific antigen were bound to the surface of the carboxyl-functionalized upconversion nanorods, which acted as the energy donor in this LET system. Gold nanorods with an absorption band at ~666 nm were synthesized by the seed growth method, acted as the energy acceptor. The emission band of the upconversion nanorods overlapped well with the absorption band of the gold nanorods. The luminescence was quenched because of the electrostatic interactions that shortened the distance between the donor (negatively charged) and the accepter (positively charged).When the PSA antigen was added into the system, the energy acceptor and the energy donors were separated because the binding affinity between PSA and anti-PSA was greater than the electrostatic interactions, and thereby the luminescence was recovered. The linear range of detecting PSA was from 0.1172 to 18.75 ng/mL ( R =0.995), with a limit of detection for PSA as low as 0.1129 ng/mL. The method was successfully applied to the sensing of PSA in human serum samples.
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RSC Advances
·
2014
·Vol. 4
·期 84
·44575-44582
·
IF 3.708
Peng Jing,Qin Wang,Baocang Liu,Guangran Xu,Yanbing Zhang,Jun Zhang,Gejihu De
We develop a facile layer-by-layer deposition process to create bi-functional Fe3O4@SiO2@Gd2O3:Yb,Er nanostructures composed of magnetic Fe3O4 cores, variable SiO2 mid-layers, and up-converting Gd2O3 shells. The synthetic process is well-controlled and the obtained Fe3O4@SiO2@Gd2O3:Yb,Er nanoparticles show relative monodispersity and exhibit tunable magnetic and up-conversion luminescence depending on the thickness of SiO2 mid-layers. The influences of SiO2 mid-buffer-layers on morphology, magnetism, and up-conversion luminescence are well addressed. The obtained bi-functional Fe3O4@SiO2@Gd2O3:Yb,Er nanoparticles may be potentially applicable in magnetic, fluorescent, and biological applications. The synthetic route may be employed for fabricating other multifunctional nanostructures.
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2017
·
IF 3.133
Qiqi Nie,Yongbo Wang,Licong Jia,Bei Liu,Enzhou Liu,Xiaoyun Hu,Jun Fan
In this paper, a novel detection method based on luminescence resonance energy transfer (LRET) system for sensitive detection of Mn 2+ ions has been proposed. The positively charged upconversion nanoparticles capped with polyethyleneimin (PEI-UCNPs) and negatively charged Ag NPs capped with tripolyphosphate (P 3 O 10 5− -Ag NPs) were bound through electrostatic interaction . They were used as energy donors and acceptors, respectively. The green upconversion luminescence could be quenched because of a good overlap between the UCNPs emission and the Ag NPs absorption spectra . Nevertheless, the LRET was disrupted and the green upconversion luminescence was restored in the presence of Mn 2+ because of the coagulation of P 3 O 10 5− -Ag NPs. Thus, the relative luminescence intensity increased as the concentrations of Mn 2+ increased. The response is linear to the concentrations of Mn 2+ in the range from 0.2 to 5 μM, and the detection limit is evaluated to be 150 nM (S/N = 3). This probe was easy to operate with satisfactory selectivity and excellent sensitivity, which would be able to satisfy the requirements of Mn 2+ -related detection.
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