Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 5
·124617
·
IF 7.5
Jinyun Lyu,Yanqian Liu,Chanjuan Liu,Xiaohua Huang
Mixed matrix membranes (MMMs) combine the flexibility of polymer membranes and the excellent gas separation performance of porous materials, and have attracted extensive attention in the field of gas separation in recent years. In this work, a novel fluorinated non-coplanar diamine monomer 2,2-bis(4-(4-amino-2-methoxyphenoxy)phenyl)hexafluoropropane (AMPH) was synthesized through molecular design. Fluorinated non-coplanar copolyimide (AFPI) was fabricated by copolymerizing AMPH with 4,4′-(hexafluoroisopropylidene)diphthalic anhydride (6FDA) and 9,9-bis(4-amino-3-fluorophenyl)fluorene (FFDA). Subsequently, Zr-BTB, a zirconium-based metal-organic framework with high CO 2 affinity and structural stability, was incorporated into the AFPI matrix to fabricate AFPI/Zr-BTB MMMs with different mass loadings. Benefiting from the introduced fluorine groups, AFPI possesses enlarged free volume to accelerate gas permeation. Meanwhile, two-dimensional Zr-BTB facilitates selective CO 2 adsorption over N 2 through thermodynamic adsorption affinity for improved separation performance. Compared with the pristine membrane, the CO 2 and O 2 permeabilities of MMMs increase by 277% and 237% at 15 wt% Zr-BTB loading, and the ideal CO 2 /N 2 and O 2 /N 2 selectivities rise by 45% and 33% at 5 wt% loading. This confirms that embedding Zr-BTB into copolyimide to fabricate MMMs is a promising strategy for developing high-performance gas separation membranes.
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高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2026
·
IF 8.3
Fan Feng,Haicheng Gao,Yuan Xue,Qing Dong,Junfeng Zhai,Dan Li,Erkang Wang,Jin Wang
Exosomes, as extracellular vesicles, represent ideal biomarkers for liquid biopsy, enabling non-invasive, sensitive, and dynamic disease monitoring. Detection or profiling of exosomes are essential for advancing exosome-based cancer diagnostics or prognostic prediction. Here, we developed an enhanced electrochemiluminescence (ECL) biosensing platform that combines magnetic enrichment with catalytic hairpin assembly (CHA), an enzyme-free DNA amplification circuit triggered by the complementary sequences of CD63 aptamer (Apt), to achieve sensitive exosome detection. The enhanced ECL signal relies on a nanocomposite of a zirconium-based metal-organic framework (Zr-MOF) and water soluble gold nanoclusters (AuNCs), denoted as Zr-MOF/AuNCs. The platform exhibits a wide linear range (6.12 × 10² - 6.12 × 10⁷ particles/mL) and a low detection limit (187.4 particles/mL) for tumor-derived exosomes. Spike-recovery assays in complex serum matrices and high specificity confirm its robustness and clinical potential. By combining magnetic preconcentration, signal amplification via Zr-MOF and CHA, and Apt-mediated recognition, this work establishes a new paradigm for non-invasive cancer diagnostics.
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JOURNAL OF MEMBRANE SCIENCE
·
2025
·
IF 9
Wenqi Ji,Wen Shen,Jiahui Li,Renjie Miao,Lianhao Li,Yaxin Zhang,Guining Chen,Guozhen Liu,Gongping Liu,Wanqin Jin
Metal-organic framework (MOF) with rich chemical functionality and tunable pore system has shown great potential for molecular separation. Facile construction of MOF membrane with precisely tailored pore structure for achieving high-efficiency liquid separation (e.g., organic solvents dehydration) remains a challenge. Herein, we proposed a ligand modulation strategy to construct Zr-MOF membranes with tunable pore structure for dimethyl carbonate (DMC) dehydration by pervaporation. Regulating the length and bulkiness of carboxylate ligands (1,4-benzenedicarboxylic acid, H 2 BDC; 1H-pyrazole-3,5-dicarboxylic acid, H 2 PZDC; fumaric acid, H 2 FUM) was applied to prepare a series of Zr-MOF membranes. The employed linear H 2 FUM ligand with the shortest length enhanced membrane surface hydrophilicity and narrowed pore size, thus facilitating the fast and selective transport of water molecules. The resulting Zr-FUM-MOF membrane exhibited an excellent dehydration performance of 2 wt% DMC/water mixtures at 35 °C with a flux of ∼5100 g m −2 h −1 and a separation factor of ∼2030, beyond the separation performance of state-of-the-arts membranes. This work paves a facile way to manipulate pore structure of MOF membranes for molecular separation.
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MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Dehao Jia,Luyang lv,Weijia Sun,Tian Tian,Binnan Shi,Nuo Zhang,Lei Yang,Qin Wei
CA15–3 serves as a tumor marker for breast cancer, and its sensitive detection is crucial for monitoring the disease and managing its treatment. In this study, an electrochemiluminescence (ECL) sensor for the detection of CA15–3 was prepared by using zirconium metal-organic frameworks (Zr-TCBPE) as an ECL emitter and Pt and Pb nanoparticles grown on graphene (rGO-PtPd) as substrate materials. The formation of a ligand bond between the 1,1,2,2-tetra(4-carboxylbiphenyl) ethylene (H 4 TCBPE) and Zr restricted the intramolecular motion of H 4 TCBPE, thereby suppressing nonradiative transitions and triggering a strong coordination-induced ECL enhancement effect. Simultaneous low-potential oxidation using N 2 H 4 as a co-reactant further significantly enhanced the ECL intensity. This method exhibited a wide detection range of 0.1 mU/mL to 500 U/mL, with a detection limit of 0.026 mU/mL. It demonstrated high accuracy and satisfactory reproducibility, indicating that the coordination-induced ECL sensing approach was highly promising for the analysis of disease biomarkers.
研究领域:
分析化学
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生物化学
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材料科学
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纳米技术
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肿瘤学
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Journal of Environmental Chemical Engineering
·
2024
·
IF 7.4
Lan Ma,Guilan Zhang,Yan Wan,Teng Wang,Xinyan Li,Yin Zhang,Tianfeng He,Rui Han,Liyun Zhang
In recent years, developing an efficient nanofiltration membrane had been a thorny challenge for dye/salt wastewater purification. In this study, a novel graphene oxide-based nanofiltration membrane (GO/UiO@S-GO-8) was constructed by intercalating the synergistic polyelectrolytes-Zr-MOF hydrated construction (UiO@S-GO) into GO nanosheets . Here, combining the hydrophilic high-density anionic sulfonic groups (SO 3 - ) with cationic amino groups (-NH 2 ), GO-based nanofiltration membrane demonstrated outstanding separation ability, anti-pollution performance and structure stability. Compared to pure GO membrane, benefiting by effective expansion of graphene layer spacing from intercalation effect of UiO@S-GO, the water permeance of GO/UiO@S-GO-8 membrane increased to 8 times (about 66.3 ± 1.5 L m −2 h −1 bar −1 ). Importantly, the permeances of various dyes wastewater also reached up to 65.1 ± 1.8 L m −2 h −1 bar −1 at the high removal rate (exceeding 99.4%). Furthermore, strong hydratability of polyelectrolytes and hard porous crystal constructed the robust anti-fouling micro/nano rough structures onto the membrane surface, which made flux recovery rate (FRR) of GO/UiO@S-GO-8 enhanced to 96.7 ± 1.3%. Remarkably, the salt-resistant behavior of the polyelectrolytes and porous MOF could maintain the stability of the membrane filtration channels, the GO/UiO@S-GO-8 membrane could realize efficient removal rate of dyes (over 98%) faced the complex dye wastewater with different salt concentrations. Meanwhile, the GO/UiO@S-GO-8 membrane also could maintain the high permeance (46.7 ± 1.5 L m −2 h −1 bar −1 ) as well as excellent removal rate (97.2 ± 1.4%) after 10 cycle experiments. Hence, the GO/UiO@S-GO-8 nanofiltration membrane with Polyelectrolytes-Zr-MOF hydrated construction possessed a broad application inspiration in the purification of high-salt/dye wastewater.
研究领域:
环境科学
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材料科学
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Journal of Water Process Engineering
·
2022
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IF 7.34
Xu Chai,Huaqi Dong,Zenggao Zhang,Zhaoyang Qi,Jie Chen,Zhixian Huang,Changshen Ye,Ting Qiu
Due to natural and production activities, mercury contamination has become one of the major environmental problems in the world. Adsorption is one of the important means to solve this problem. However, most of the commercially available adsorbents exhibit relatively low adsorption capacity and slow kinetics. Therefore, a novel 4,6-diamino-2-mercaptopyrimidine-functionalised Zr-based metal-organic framework (UiO-66-DMP) was synthesised in this study. The UiO-66-DMP was characterised through X-ray diffraction, scanning electron microscopy, energy dispersive spectrometry , X-ray photoelectron spectroscopy, Fourier-transform infrared spectrometry, and thermogravimetric analysis . The potential of the UiO-66-DMP as a superior adsorbent for Hg(II) removal and the corresponding mechanisms were evaluated through batch experiments under different conditions and density functional theory calculations. Benefitting from its high specific surface area and multiple adsorption sites, the maximum Hg(II) adsorption capacity achieved in this study was 822.00 mg·g-1, which is the highest Hg(II) adsorption capacity reported to date. In addition, under the interference of Ca(II), Cd(II), Co(II), Mg(II), Mn(II), Ni(II), Cr(III), Cu(II), Zn(II) and other coexisting ions, the UiO-66-DMP could still maintain the high selective adsorption capacity for Hg(II). According to the characterization analysis and DFT calculation results, the adsorption of Hg(II) onto the UiO-66-DMP was dependent on electrostatic and covalent interactions between metal ions and abundant functional groups on the UiO-66-DMP surface.
研究领域:
环境科学
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材料科学
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化学工程
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高影响因子
Advanced Science
·
2023
·Vol. 10
·期 31
·2304149
·
IF 15.1
Qiuyu Ye,Enxian Yuan,Jin Shen,Mingli Ye,Qin Xu,Xiaoya Hu,Yun Shu,Huan Pang
CsPbX 3 perovskite nanocrystal (NC) is considered as an excellent optical material and is widely applied in optoelectronics. However, its poor water stability impedes its study in enzyme-like activity, and further inhibits its application in biomimetic cascade catalysis. Herein, for the first time, the oxidase-like and ascorbate oxidase-like activities of an amphiphilic polymer capped CsPbX 3 are demonstrated, and its catalytic mechanism is further explored. Furthermore, an all-nanozyme cascade system (multifunctional CsPbBr 3 @Zr-metal organic framework (Zr-MOF) and Prussian blue as oxidase-like and peroxidase-like nanozyme) is constructed with a portable paper-based device for realizing the dual-mode (ratiometric fluorescence and colorimetric) detection of ascorbic acid in a point-of-care (POC) fashion. This is the first report on the utilization of all-inorganic CsPbX 3 perovskite NC in biomimetic cascade catalysis, which opens a new avenue for POC clinical disease diagnosis.
研究领域:
生物医学工程
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材料科学
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纳米医学
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PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2026
·
IF 4.6
Minzhe Li,Yiwen Gui,Ao Chen,Ning Cai,Jumei Li
In this study, Ag@NU-66 core-shell composites were synthesized by coating silver nanospheres with the metal organic framework (MOF)-UiO-66-NH₂ (Zr) using a straightforward hydrothermal technique. The resulting composite combines excellent stability, high enrichment capacity, and photocatalytic properties. As a SERS substrate, Ag@NU-66 effectively detected a range of harmful contaminants, with detection limits as low as 10 −9 M, 10 −8 M, and 10 −9 M for methylene blue, rhodamine 6G, and thiram, respectively. In addition, Ag@NU-66 exhibited efficient removal of these pollutants under simulated solar light photocatalysis. The dual functionality of the composite can be attributed to the enhanced electromagnetic field created by the plasmonic properties of silver nanospheres, along with improved charge transfer facilitated by the adsorption capabilities of UiO-66-NH₂. Furthermore, the Ag@NU-66 composites demonstrated superior stability compared to bare silver nanospheres in various solvents, even in oxidative conditions containing halide ions. These findings support the potential development of Ag@NU-66-based sensing and pollutant removal systems for environmental applications.
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PubMed
高影响因子
INORGANIC CHEMISTRY
·
2025
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IF 4.7
Tao Cheng,Lu Liu,Jia Hui Chen,Pan Wang,Jian Ming Pan
Metal–organic frameworks (MOFs) exhibit a diverse array of applications in the fields of adsorption, catalysis, sensing, and separation. However, the limited water stability of MOFs poses challenges in the separation domain, particularly due to the structural similarities among water-soluble nucleoside compounds, which complicate the selective adsorptive separation of these compounds from complex mixtures. In this study, hydrophilic flower-like zirconium-based MOF nanosheets (Zr-FNSs) were prepared by a one-step hydrothermal method. The investigation focused on their adsorption capacity and the mechanism of action, with respect to various nucleosides. Adsorption experiments were conducted under varying pH conditions to identify the optimal pH and to assess the influence of phosphate number on the adsorption of adenosine compounds. The kinetic adsorption capacities of Zr-FNSs for adenosine monophosphate (AMP), adenosine diphosphate (ADP), and adenosine triphosphate (ATP) were determined to be 254.81, 211.35, and 182.97 μmol g–1, respectively, demonstrating a gradient decrease that may be attributed to increased spatial resistance or a limited number of available adsorption sites. Zr-FNSs have excellent regenerative properties. This work underscores the significance of functional group interactions in the selective adsorption of nucleoside and provides valuable insights for the design of MOF-based adsorbents for the selective separation and purification of nucleoside.
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PubMed
高影响因子
BIORESOURCE TECHNOLOGY
·
2025
·
IF 9
Jiao Long,Yan Gao,Kangjia Sheng,Junjie Yao,Xinglong Zheng,Tao Bao,Wanghui Jing,Sicen Wang
The research on the reuse of resources is crucial for achieving high-value utilization of traditional Chinese medicine (TCM). In this study, licorice residues were selected to extract fibers by alkaline hydrogen peroxide oxidation because of their high cellulose content and widespread use. The cellulose, hemicellulose and lignin content of obtained fibers were found to be 55 %, 8.2 % and 18.8 %, respectively. Immobilizing MOF-808 onto licorice residue fibers yields a composite material exhibiting enhanced adsorption capabilities. The synthesized material was employed to adsorb ketoprofen, naproxen and diclofenac sodium. The characterization results confirmed the successful modification. Adsorption performance experiments indicate that the adsorption behavior follows pseudo-second-order kinetic models and Langmuir isotherm. The adsorption is a process of rapid adsorption and slow equilibrium, showing satisfactory adsorption capacity. X-ray photoelectron spectroscopy and density functional theory calculation revealed that the sustained adsorption attributed to the synergy of π-π stacking, hydrogen bonding and coordination interaction. This study emphasizes the potential for reusing licorice residues and paves the way for the treatment of TCM residue after extracting active ingredients.
研究领域:
环境科学
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材料科学
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化学工程
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纳米技术
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可持续化学
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药学
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PubMed
高影响因子
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
·
2025
·
IF 4.6
Jianmei Li,Qi Sun,Haiyu Li,Zongyao Zhao,Ting Gong,Mengqin Xiang,Feng Gao,Yong Tang
Traditional DNA purification methods face limitations in efficiency and complexity, particularly for food authenticity verification. To address this, we developed novel magnetic nanocomposites by integrating polydopamine-coated Fe 3 O 4 nanoparticles (Fe 3 O 4 @PDA) with zirconium-based metal-organic frameworks (Zr-MOFs) functionalized via varying organic ligands (terephthalic acid, 2-aminoterephthalic acid, and 1,2,4-benzenetricarboxylic acid). The resulting materials—MUIO-66, MUIO-66-NH₂, and MUIO-66-COOH—were characterized for structure, magnetism, and DNA adsorption performance. MUIO-66-COOH exhibited superior efficiency, achieving >80 % DNA recovery from camel meat under optimized conditions (25 °C, 10 min), outperforming commercial kits. Adsorption kinetics and isotherms revealed a multilayer process (Freundlich model) governed by pseudo-second-order kinetics, driven by "salt-bridge" interactions between DNA phosphate groups and surface carboxyl moieties. The method demonstrated high precision (RSD = 2.75 %), reproducibility, and reusability (>81 % efficiency after 5 cycles). This work establishes a rapid, ligand-tunable magnetic solid-phase extraction (MSPE) platform for high-quality DNA extraction, advancing biosensing applications in food authenticity.
研究领域:
纳米技术
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遗传学
·
食品科学
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材料科学
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分析化学
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生物技术
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高影响因子
APPLIED SURFACE SCIENCE
·
2024
·
IF 6.3
Bo Liu,Liangliang Xiong,Xiaoqiang Fan
In this work, two-dimensional UiO-67 nanosheets are successfully modified on graphene oxide (GO). The synthesized GO@2D-UiO-67 composite not only exhibits the electrical insulation characteristics of Zr-MOF, but also leverages the passive barrier effect of its 2D layered structure to prepare a highly anticorrosive epoxy coating. Electrochemical measurements reveal that the impedance modulus of the GO@UiO-67/EP composite coating remain two orders of magnitude higher than that of the pure EP coating even after 28 days of immersion in 3.5 wt% NaCl solution. This good long-term anti-corrosion performance could derive from the enhanced crosslinking density of composite coating due to the incorporation of GO@UiO-67 nanosheets. Furthermore, the shielding effect of layered structure and the corrosion inhibition behavior of organic ligands are proved to improve the corrosion resistance properties of composite coating. This research fills the application void of two-dimensional Zr-MOF composites in resin coatings, as well as serves as a forward-looking initiative to enhance the long-term corrosion protection of epoxy resin coatings.
研究领域:
材料科学
·
腐蚀与防护
·
纳米技术
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高影响因子
危险品化学品经营许可证（带存储）