FOOD CHEMISTRY
·
2026
·
IF 10.4
Xiaoyun Fei,Yushi Wei,Yao Wang,Zhenjing Huang,Deming Gong,Guowen Zhang
WP-GA-PC emulsion has excellent environmental and oxidative stability. • The stability of WP-GA-PC emulsion was affected by pH, salt and temperature. • WP-GA-PC emulsion showed better β-carotene protection than WP and WP-GA emulsion. • WP-GA-PC emulsion was an effective way for β-carotene delivery. β-carotene is a bioactive lipophilic compound, but its low water solubility and environmental sensitivity limit its use in food industry. In this study, β-carotene-loaded oil/water emulsions were constructed using whey protein (WP)-gallic acid (GA)-pectin (PC) ternary covalent conjugates as interfacial stabilizers, and the relationship among pH-dependent interfacial behavior, emulsion stability, and β-carotene digestion characteristics were investigated. The WP-GA-PC conjugate exhibited the most favorable interfacial adsorption behavior at pH 5 and formed a more elastic interfacial film, resulting in emulsions with the smallest particle size (30.51 μm) and excellent thermal and salt ion stability. Rheological analysis showed that all emulsions exhibited shear-thinning behavior, while pH value markedly affected their apparent viscosity. The encapsulation rates of β-carotene in pure oil, WP, WP-GA and WP-GA-PC emulsions were 70.83%, 90.07%, 93.17% and 96.25%, respectively. The bioaccessibility of β-carotene was 13.73% and 8.67% higher in WP-GA-PC emulsion than in WP emulsion and WP-GA emulsion, respectively. This work provides a scientific basis for designing protein-polyphenol-polysaccharide covalent conjugate-based emulsion delivery systems for lipophilic bioactive compounds. Download: Download high-res image (256KB) Download: Download full-size image
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ELECTROCHIMICA ACTA
·
2026
·
IF 5.8
Senyang Song,Fangfang Shang,Mengwei Yin,Qianqian Wang,Yi Liu,Ran Bi,Xiaoyan Ma
Gallic acid (GA) chelates with exposed metal active sites of Ni/Co-DABD MOF, effectively protecting metal ions and elevating MOF coordination stability. • The GA-modified Ni/Co-DABD MOF@NH₂-MXene composite electrode delivers a high specific capacitance of 2044 F g -1 at 1 A g -1 with superior rate capability and cycling durability. • GA modification strengthens the interfacial synergy between MOF and NH₂-MXene, significantly boosting charge transfer efficiency and structural stability of the composite. The limited active sites and poor electrochemical structural stability of metal-organic frameworks (MOF) severely limit their application in electrochemical energy storage. In this study, we used the acid properties of gallic acid (GA) as an etching agent to etch MOF surface active sites. Subsequently, the protonated GA is further chelated with the exposed metal active site, which can effectively protect the metal ions. At the same time, GA provides a large number of phenolic hydroxyl groups, which greatly improves the coordination stability of MOF. A new MOF@MXene composite electrode material was obtained by solvothermal synthesis of GA-modified MOF and aminated MXene. The electrochemical test results show that the new MOF@MXene composite electrode material synthesized by this scheme has high specific capacitance and high rate stability. The functional modification of MOF by GA greatly improves the synergistic binding performance between MOF and MXene, and thus significantly improves the electrochemical stability of composite electrode materials. The mechanism of the electrochemical reaction was investigated by in-situ X-ray diffraction and theoretical calculation. In this paper, the functional mechanism of polyphenols on MOF is described, which provides a new idea for the electrochemical application of MOF. The GA-modified Ni/Co-DABD MOF@NH₂-MXene composite electrode delivers a high specific capacitance of 2044 F g -1 at 1 A g -1 with superior rate capability and cycling durability. Download: Download high-res image (296KB) Download: Download full-size image
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FOOD RESEARCH INTERNATIONAL
·
2025
·
IF 8
Xiaoyun Fei,Hui Xue,Hongtao Chen,Taotao Dai,Deming Gong,Guowen Zhang
This work aimed to determine the effect of glycosylation on the emulsifying property and interfacial behaviors of whey protein (WP) - gallic acid (GA) conjugates. By grafting pectin (PC) with WP-GA conjugates via a glycosylation reaction, WP-GA-PC ternary covalent conjugates were synthesized. The degree of grafting increased significantly with the increase of PC concentration and reached 22.90 % when the mass ratio of WP-GA to PC was 1:4. Moreover, the thermal stability and emulsifying property of the WP-GA-PC ternary conjugates were significantly improved compared with the WP-GA conjugates. The addition of PC improved the interfacial properties of the conjugates, which was favorable to the formation of stable emulsions. The emulsion activity index and emulsion stability index were increased by 10.73 m 2 /g and 86.70 min, respectively, at a mass ratio of 1:4 of WP-GA to PC. This work may provide a new idea for the development of novel stabilizers applied in the emulsion systems.
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高影响因子
ELECTROANALYSIS
·
2026
·Vol. 38
·期 4
·e70149
·
IF 2.6
Haixu Wang,Xiaonan Qi,Shunli Zhou,Rongsong Cao,Xi Yang,Le Li,Zhen Sun
Gallic acid (GA) is a natural polyphenol known for its significant biological activity and widespread presence in food, medicine, and various other fields. The accurate and rapid detection of GA is crucial for ensuring food quality control and conducting pharmaceutical analyses. In this study, we successfully developed a novel electrochemical sensor based on a ZIF-67/pomelo carbon (ZIF-67/PC) composite through a simple and environmentally friendly synthetic route. The results indicated that the glassy carbon electrode (GCE) modified with ZIF-67/PC exhibited remarkable electrocatalytic activity towards GA oxidation. The pore-like structure of ZIF-67/PC accelerates the diffusion of GA, the carbon matrix enhances electron transfer, and the Co-N-C sites catalyze the oxidation of GA, thereby achieving excellent detection performance. Under optimal conditions, the sensor demonstrated an extensive linear response range of 8–1000 μM for GA, accompanied by a low detection limit of 0.25 μM (S/N = 3). Furthermore, this sensor displayed excellent selectivity as well as good stability-retaining 91.27% current after 15 days and satisfactory reproducibility with a relative standard deviation below 2%. When applied to detect GA in green tea samples, recovery rates ranged from 95.2% to 102.1%, underscoring its practical application potential. This work presents a viable strategy for developing low-cost yet high-performance electrochemical sensors by integrating metal–organic frameworks with biomass-derived carbon materials.
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Frontiers in Bioengineering and Biotechnology
·
2023
·
IF 5.7
Pang Yuxuan,Guan Lin,Zhu Yanlin,Niu Ruijuan,Zhu Song,Lin Quan
An open critical-size bone defect is a major medical problem because of the difficulty in self-healing, leading to an increased risk of bacterial infection owing to wound exposure, resulting in treatment failure. Herein, a composite hydrogel was synthesized by chitosan, gallic acid, and hyaluronic acid, termed “CGH.” Hydroxyapatite was modified with polydopamine (PDA@HAP) and introduced to CGH to obtain a mussel-inspired mineralized hydrogel (CGH/PDA@HAP). The CGH/PDA@HAP hydrogel exhibited excellent mechanical performances, including self-healing and injectable properties. Owing to its three-dimensional porous structure and polydopamine modifications, the cellular affinity of the hydrogel was enhanced. When adding PDA@HAP into CGH, Ca2+ and PO43- could release and then promoted differentiation of BMSCs into osteoblasts. Without any osteogenic agent or stem cells, the area of new bone at the site of defect was enhanced and the newly formed bone had a dense trabecular structure after implanting of the CGH/PDA@HAP hydrogel for 4 and 8 weeks. Moreover, the growth of Staphylococcus aureus and Escherichia coli was effectively inhibited through the grafting of gallic acid onto chitosan. Above, this study provides a reasonable alternative strategy to manage open bone defects.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2022
·
IF 8.025
Wen Zhang,Qing-Min Zeng,Ren-Cheng Tang
In recent years, the serious influence of infectious diseases on public health and economy development has raised global awareness of the importance of medical textiles for preventing and curing injuries and diseases. The application of biomass molecules is a feasible and sustainable approach to design multipurpose medical materials. In this work, a novel cotton fiber with antibacterial, antioxidant, and drug delivery properties was prepared using gallic acid functionalized polylysine (GA-PL). GA-PL was synthesized by immobilizing GA onto PL using the carbodiimide coupling method. The content of GA immobilized onto PL was 117.9 mg/g. The as-prepared GA-PL was grafted onto oxidized cotton by means of the Schiff base reaction between the amino groups of GA-PL and the aldehyde groups of oxidized cotton. The content of GA-PL grafted onto cotton fiber was 205.1 mg/g. GA-PL grafted cotton fiber exhibited not only durable antibacterial and antioxidant activities but also good drug loading and releasing properties for acetylsalicylic acid. This work presents a novel, cleaner, and sustainable approach to prepare medical cotton fibers with bioactive and drug delivery properties.
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高影响因子
GREEN CHEMISTRY
·
2023
·Vol. 26
·期 3
·1627-1636
·
IF 9.8
Shengzong Lan,Peilun Shen,Qifang Zheng,Lidong Qiao,Liuyang Dong,Dianwen Liu
Apatite and dolomite present challenges in their separation due to their similar surface chemistry. To achieve flotation separation of apatite and dolomite, depressants are required, but conventional depressants have several drawbacks. Hence, the development of effective and environmentally friendly depressants is of great importance. This study aimed to investigate the depressive effect of gallic acid (GA) on the flotation separation of apatite from dolomite using sodium oleate (NaOL) as the collector. The floatability of apatite and dolomite was examined through micro-flotation. The findings revealed that, with 1.0 × 10−4 mol L−1 NaOL, the recovery rates of apatite and dolomite were 86.29% and 77.42%, respectively. After introducing 2.0 × 10−4 mol L−1 GA, the recovery of apatite remained at 83.42%, while that of dolomite drastically decreased to only 14.33%. The selective depression mechanism of GA in the flotation separation of apatite from dolomite was investigated using various techniques, including zeta potential, contact angle, UV-vis, FTIR, XPS, ToF-SIMS, and AFM analyses. The results demonstrated that GA increased the hydrophilicity of the dolomite surface and impeded the adsorption of NaOL on that surface without affecting the apatite. GA was found to bind to Ca and Mg sites on the dolomite surface through –OH and –COOH groups. The adsorption of GA on the dolomite surface was substantial, with the adsorption height primarily concentrated in the range of 10–30 nm. GA exhibited selective depression on dolomite, thus, enabling successful flotation separation of apatite from dolomite.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2023
·
IF 8.2
Liling Fu,Qiong Xiao,Yi Ru,Qinglin Hong,Huifen Weng,Yonghui Zhang,Jun Chen,Anfeng Xiao
Antioxidant and antimicrobial agarose coatings were developed by grafting gallic acid through the carbodiimide coupling method. Structural characterization revealed that the carboxyl group of gallic acid was successfully grafted onto the C6-OH of D-galactose in agarose, with the highest observed grafting ratio being 13.73 %. The grafting of gallic acid significantly increased the antioxidant and bacteriostatic activities of the agarose. As the grafting ratio of gallic acid-modified agarose (Ga Ag) increased from 0 to 13.73 %, the scavenging ratio of DPPH and the inhibition ratio of β -carotene bleaching were observed to increase from 0 % to 65.92 % and 6.89 % to 73.46 %, respectively. Ga Ag exhibited up to 100 % inhibition of Escherichia coli and Staphylococcus aureus . The physicochemical properties of gel strength , viscosity, gelling temperature and melting temperature decreased to 971.3 g/cm 2 , 17.9 mPa·s, 31.7 °C and 84.1 °C, respectively. The gel contact angle was increased from 22.1° to 73.6°. Fish preservation tests have demonstrated that it effectively inhibited bacterial growth, prevented fat oxidation , blocked light, reduced moisture loss, and enhanced the overall quality of grass carp ( Ctenopharyngodon idellus ) fillets during refrigeration, which was more effective than native agarose in extending the shelf life of fish. Therefore, Ga Ag holds promise as an aquatic product preservative.
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FOOD HYDROCOLLOIDS
·
2023
·
IF 10.7
Yuzhong Yan,Shuling Chen,Le Deng,Yuxuan Duan,Zhaohua Huang,Deming Gong,Guowen Zhang
In this work, the egg white protein-gallic acid-xanthan gum covalent complexes were used to construct emulsions and oleogels and the effects of different concentrations of the complexes on the properties of emulsions and oleogels were investigated. The results showed that the values of emulsion D[4,3] and ζ-potential decreased with increasing complex concentration, while the emulsion stability index increased. The emulsions exhibited good centrifugal stability against changes in temperature, salt ion concentration and pH value. The emulsions prepared with high concentrations of the complexes (0.6–1.0%, wt) showed good viscoelasticity and gelation properties. The oil binding capacity increased from 75.86% to 98.04% as the concentration of oleogel increased from 0.2% to 0.4% (wt), and all the oleogels exhibited a strong gel network structure (G'>G″). Compared with the bulk oil, the oleogel had a stronger antioxidant capacity, and with increasing the concentration of the complexes, the antioxidant ability of the produced oleogel enhanced. This study may provide a theoretical basis for the preparation of protein-polysaccharide-polyphenol based oleogels and their application as solid fat substitutes in the food industry.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2021
·
IF 6.953
Dongyan Shen,Qiaobin Hu,Jing Sun,Xinyi Pang,Xiangfei Li,Yingjian Lu
We incorporated oxidized dextran (Odex) into nanoparticles composed of gallic acid-modified chitosan (GA-CS) and sodium caseinate (NaCas). The mass ratio of GA-CS to NaCas and the pH of the reaction solution were optimized to obtain nanoparticles with excellent performance and stability. The interactions among various nanomaterials were confirmed by Fourier-transform infrared spectroscopy (FT-IR) and fluorescence spectrometer. The optimized complex nanoparticles had a diameter of approximately 131.2 nm with a polydispersity index (PDI) of 0.14, and a zeta potential of 26.2 mV. Our results showed that Odex enhanced the stability and function of GA-CS/NaCas nanoparticles (NP). At a curcumin loading of 10%, the encapsulation efficiency of Odex-crosslinked GA-CS/NaCas (NP (Odex)) was 96.2%, whereas that for uncrosslinked nanoparticles was 66.9%. Compared to the burst release profile of free curcumin in simulated GI fluids, the sustained release profile of encapsulated curcumin was observed. Radical-scavenging assays confirmed that the nanoparticles had excellent antioxidant activity themselves due to the grafting of phenolic acid on chitosan backbone. Overall, NP (Odex) with good GI stability and antioxidant activity hold promising for the oral delivery of hydrophobic bioactives.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2020
·
IF 5.774
Chengcai Li,Xingyu Chen,Jie Luo,Feng Wang,Guojin Liu,Hailin Zhu,Yuhai Guo
A kind of PVDF composite membrane of good hydrophilic performance and antibacterial property was developed via an in-situ blending process. The PVDF-g-PGAL powder was prepared by degrading PVDF powder in alkaline condition, then oxidizing and grafting with Gallic acid (GAL). After mixing the original PVDF and PVDF-g-PGAL powder to prepare the PVDF composite membrane was soaked in NaHSO 3 to further improve its hydrophilicity. The oil-in-water emulsion separation efficiency of the composite membrane was regulated by varying the contents of the modified PVDF powder. When the content arrives at 30%, the composite membrane has the pore sizes in the range of 130.2–263.3 nm, the permeation flux of 2419.9L⋅m −2 ⋅h −1 ⋅bar −1 , the oil rejection rate of 97.39%, the flux recovery rate (FRR) of 94.59% and possesses the good anti-fouling performances during the cross-flow separation of the oil-in-water emulsion with the particle sizes within the scope of 10.1–396.1 nm. In addition, it has excellent antibacterial properties against E. coli and S. aureus, and effectively solves the blocking of membrane pores caused by the surface colonies in application. Therefore, the new composite PVDF membrane has the broad application prospects in the practical treatment of the complex oily wastewater media.
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JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2020
·
IF 3.807
Cuizhu Ye,Xingguang Chen,Junjun Xu,Huiting Xi,Tiantian Wu,Danwen Deng,Jinsheng Zhang,Ganhui Huang
Supported by metal-organic frameworks (MOFs), a new molecular imprinted electrochemical sensor (MIES) taking nano-structure Co 2+ @Fe 3 O 4 as the support point of receptor was developed for highly sensitive detection of GA in this paper. Gold electrode was modified with Co 2+ @Fe 3 O 4 , then Co 2+ @Fe 3 O 4 /Au was soaked and compounded to Fe 3 O 4 @ZIF-67/Au. MIPs film was obtained by potentiostatic polymerization with polypyrrole as monomer and GA as template. SEM, EDS, FTIR, XRD, DPV and EIS characterizations indicate the success of the preparation of the modified electrode . By optimization, the Δ i response of MIP/Fe 3 O 4 @ZIF-67/Au was strengthened from 25.38 μA to 30.84 μA. The MIP/Fe 3 O 4 @ZIF-67/Au sensor showed a superior sensitivity with a lower LOD of 0.297pM (S/N = 3) and a wider linear range of 6–600pM for GA detection, which profits from the combination of high surface area of Co 2+ @Fe 3 O 4 and high porosity of MOFs. Because of the specificity of molecular imprinted polymers (MIPs), our sensor showed advanced selectivity and not affected by similar structure interfering substances. In addition, the stability, reproducibility and real-sample detection were also satisfactory with the recovery rates between 89.5% and 118.4% and the RSD were lower than 5.5%. This sensitive and simple method can be further used to prepare polypyrrole-based MIES suported by MOFs-Co 2+ @Fe 3 O 4 for highly sensitive detection of other small and weight molecules.
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