APPLIED SURFACE SCIENCE
·
2026
·
IF 6.6
Ruijie Che,Yubo Pan,Yining Zhu,Xiaojing Long,Jining Li
Visible-light purification of contaminated waters is often constrained by rapid charge recombination and strong matrix interference, especially in complex real wastewaters. Here, we upcycled rice-noodle waste into carbon quantum dots (CQDs), and integrated them with ZnIn 2 S 4 to construct three-dimensional CQDs/ZnIn 2 S 4 nanoflowers. Optimising the CQDs loading at 3 wt% enabled the composite to remove 50 mg L −1 of pollutants within 120 min under visible irradiation, achieving 99.3% Cr(VI) reduction and complete methylene blue (MB) degradation with apparent first-order rate constants of 0.0192 min −1 (Cr(VI)) and 0.0223 min −1 (MB). The photocatalyst resisted matrix inhibition, with removals reaching 93.1% (Cr(VI)) and 91.6% (MB) in wastewaters, and above 95% in tap, lake and river waters; catalytic activity was retained above 95% after five reuse cycles. Valence-band X-ray photoelectron spectroscopy (VB-XPS) and density functional theory (DFT) band alignment analysis, together with transient photocurrent response, electrochemical impedance spectroscopy (EIS), photoluminescence (PL)and electron paramagnetic resonance (EPR) and radical-trapping experiments collectively verified an S-scheme CQDs/ZnIn 2 S 4 heterojunction with an interfacial built-in electric field that drives vectorial charge separation and preserves highly reductive electrons and oxidative holes at spatially distinct sites. This waste-to-resource strategy couples low-cost carbon precursors with interfacial band engineering to deliver a scalable, visible-light-driven platform for simultaneous detoxification of inorganic (Cr(VI)) and organic dye pollutants in realistic treatment scenarios.
✓ 已验证
产品关联
DOI
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2019
·
IF 9.518
Chengxi Zhu,Dong Liu,Yuye Li,Xiuli Shen,Shuai Ma,Yang Liu,Tianyan You
A novel ratiometric electrochemical aptasensor was developed for Ochratoxin A (OTA) detection based on the binding of methylene blue (MB) to DNA with a dual signal amplification strategy. The formation of dsDNA structures between ferrocene-labeled complementary DNA (Fc-cDNA), the OTA aptamer , and complementary helper DNA (hDNA) caused Fc away from the electrode, and allowed dsDNA to bind with a certain amount of MB. Here, a small oxidation current of Fc (I Fc ) and a large oxidation current of MB (I MB ) were obtained. In the presence of OTA, its specific recognition with the aptamer induced the release of aptamer and hDNA from the electrode and subsequently the formation of hairpin structure for cDNA, which caused Fc close to the electrode and a weaker binding ability with MB. Then, an increased I Fc and a decreased I MB were obtained. Based on this principle, OTA could be accurately quantified by measuring the ratiometric signal of I Fc /I MB . Herein, the dual signal amplification strategy of the introduction of hDNA and the binding with MB after the OTA recognition was exploited to amplify the response signal. The obtained aptasensor showed a linear detection range from 10 pg mL −1 to 10 ng mL −1 and a detection limit of 3.3 pg mL −1 . The aptasensor was successfully applied to determine OTA in wheat, and the results were validated through HPLC-MS. Furthermore, by changing the target aptamers, this strategy could be universally used for the determination of various mycotoxins , showing promising potential applications for mycotoxins monitoring in agricultural products and foods.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICAL CHEMISTRY
·
2023
·
IF 7.4
Yanhong Wang,Han Jie,Huajuan Ye,Yuanyuan Zhang,Ning Li,Junyang Zhuang
Improving the convenience, sensitivity, and cost-effectiveness of electrochemical biosensors is crucial for advancing their clinical diagnostic applications. Herein, we presented an elegant approach to construct electrochemical aptasensors for tumor-derived exosome detection by harnessing the alterable interaction between methylene blue (MB) and DNA aptamer. In detail, the anti-EpCAM aptamer, named SYL3C, was found to exhibit a strong affinity toward MB due to the specific interaction between MB and unbound guanine bases. Thereby, SYL3C could be stained with MB to arouse a strong electrochemical signal on a gold electrode (AuE). Upon binding to EpCAM-positive exosomes, SYL3C underwent a conformational transformation. The resulting conformation, or exosomes-SYL3C complex, not only reduced the accumulation of MB on SYL3C by obstructing the accessibility of guanines to MB but also impeded the transfer of electrons from the bound MB to AuE, leading to a notable decrease in the electrochemical signal. Using MB-stained SYL3C as an electronic switch, an electrochemical aptasensor was readily established for the detection of EpCAM-positive exosome detection. Without the need for signal amplification strategies, expensive auxiliary reagents, and complex operation, this unique signal transduction mechanism alone could endow the aptasensor with ultrahigh sensitivity. A limit of detection (LOD) of 234 particles mL–1 was achieved, surpassing the performance of most reported methods. As a proof of concept, the aptasensor was applied to analyze clinical serum samples and effectively distinguish non-small-cell lung cancer (NSCLC) patients from healthy individuals. As EpCAM exhibits broad expression in exosomes derived from different tumor sources, the developed aptasensor holds promise for diagnosing other tumor types.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
IET Nanobiotechnology
·
2018
·Vol. 12
·期 4
·441-445
·
IF 2.059
Xiaojie Song,Xianyang Shi,Mi Yang
Biosynthesised nanocomposites have attracted growing interests attributed to their ‘green’ synthesis nature in recent years. Shewanella oneidensis MR-1, a dissimilatory metal-reducing bacterium, was used to reduce palladium (II) nitrate to palladium (0) nanoparticles (Pd NPs) under anaerobic conditions, resulting in the in situ formation of Pd NPs immobilised on TiO 2 nanotubes (TNTs) (Pd/TNTs nanocomposites). The Pd/TNTs nanocomposites were characterised by transmission electron microscopy, X-ray diffraction, X-ray photoelectron spectroscopy, energy dispersive X-ray, and electron spin resonance, respectively. The results indicated that Pd NPs are successfully grown on the TNTs without aggregation. Photocatalytic degradation of methylene blue (MB) by Pd/TNTs nanocomposites under simulated sunlight was also investigated. Pd/TNTs nanocomposites had photocatalytic efficiency superior to that of single TiO 2 nanomaterials. The photocatalytic activity of Pd/TNTs nanocomposites can be enhanced by S. oneidensis MR-1. The results showed that after only 10 min, the degradation ratio of MB reached 98.7% by Pd/TNTs nanocomposites when simultaneously assisted with S. oneidensis MR-1.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2017
·
IF 7.78
Yan Li,Junlin He,Jun Chen,Yazhen Niu,Yilin Zhao,Yuchan Zhang,Chao Yu
In this study, a dual-type responsive electrochemical immunosensor was developed for the quantitative detection of proprotein convertase subtilisin/kexin type 9 (PCSK9), a potential biomarker of cardiovascular disease in serum. N-doped graphene nanoribbons (N-GNRs) with good conductivity were used as the sensing matrix modifying the glassy carbon electrode. Palladium platinum alloy (PdPt) nanoparticles with high catalytic performance toward the reduction of hydrogen peroxide (H 2 O 2 ) were reduced onto amino-functionalized fullerene (n-C 60 -PdPt) and significantly amplified the electrochemical signal recorded by the amperometric i-t curve. Furthermore, staphylococcus protein A (SPA) with antibody orientation function was introduced to improve the immunoreaction efficiency. Accordingly, a label-free immunosensor was fabricated based on n-C 60 -PdPt/N-GNRs for the quick detection of PCSK9. Meanwhile, to realize ultrasensitive detection of PCSK9, Pt-poly (methylene blue) (Pt-PMB) nanocomposites synthesized by a one-pot method for the first time were used as a novel signal label, which exhibited uniform morphology as well as good conductivity and produced an electrochemical signal recorded by differential pulse voltammetry (DPV). Herein, a novel sandwich-type immunosensor was designed using n-C 60 -PdPt/N-GNRs as the sensing matrix and Pt-PMB as the signal label for sensitive detection of PCSK9. Under optimal conditions, the label-free immunosensor showed a linear range of 10 pg mL −1 to 100 ng mL −1 with a detection limit of 3.33 pg mL −1 (S/N=3), and the sandwich-type immunosensor exhibited a linear range of 100 fg mL −1 to 100 ng mL −1 with a detection limit of 0.033 pg mL −1 (S/N=3) for PCSK9 detection, indicating its potential application in clinical bioassay analysis.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2025
·
IF 5.4
Xin Li,Xinxin Liu,Dongjie He,Xin Wang,Nuo Xu,Ke Li,Aimin Lv,Qun Liu,Yu Zhang
Organic dyes containing azo/anthropquinone groups pose severe ecological risks due to their toxicity and persistence. Therefore, in this study, covalently cross-linked agarose aerogel was used as the substrate, and the Cu-BTC metal-organic framework (Cu-MOF) was loaded via in-situ growth at room temperature to prepare a Cu-MOF @ agarose composite aerogel (Cu-MOF@AGA) adsorbent. The introduction of Cu-MOF endows Cu-MOF@AGA with more adsorption sites and a larger specific surface area (210.78 m²/g). The characteristic peaks at 2θ values of 6.6, 9.4, and 11.5 in the XRD pattern indicate the successful loading of Cu-MOF. Meanwhile, SEM images show that the 3D macroporous structure of Cu-MOF @AGA provides a rapid mass - transfer channel for pollutant molecules. FT-IR results reveal that Cu-MOF@AGA has more functional groups (such as -OH, -COOH) and active sites. The adsorption mechanism was analyzed using XPS and FT-IR, revealing that the adsorbent achieves adsorption of methylene blue (MB) and Congo red (CR) through hydrogen bonding, π-π interactions, and electrostatic interactions. Kinetic and isotherm fitting analyses demonstrated that the maximum adsorption capacities for methylene blue and Congo red reached 59.48 and 159.85 mg/g, respectively. Finally, after five cycles of adsorption experiments, the removal rates for MB and CR remained above 85 %, indicating that the adsorbent exhibits excellent reusability and promising application potential.
✓ 已验证
产品关联
DOI
高影响因子
Frontiers in Chemistry
·
2025
·
IF 4.2
Changfeng Zhu,Hongxin Wang,Jiyang Liu
As an important inflammatory cytokine, interleukin-6 (IL-6) can mediate the entire pathological process of periodontitis and is closely associated with the degree of inflammation. Therefore, it is critical to develop convenient quantitative methods for monitoring IL-6 quantity in gingival crevicular fluid. In this study, methylene blue (MB)-decorated reduced graphene oxide (rGO) is employed as signal probe to further support the antibody-enabling specific recognition of IL-6. Due to π–π stacking and electrostatic interactions, rGO-MB nanocomposites can be stably obtained. rGO with good conductivity and large surface area characteristics promotes the redox signals of MB on the glassy carbon electrode (GCE). In addition, through the simple in situ self-polymerization of dopamine, the polydopamine (PDA) obtained can be not only directly used as a biological crosslinking agent for covalent immobilization of anti-IL-6 antibody but can also be regarded as a protective layer to enhance the stability of rGO-MB on the GCE surface. Such a designed PDA/rGO-MB/GCE-based immunosensor enables specific binding with IL-6 and produces a decreased electrochemical signal for MB, realizing the selective and sensitive quantitative measurement of IL-6. Consequently, our fabricated PDA/rGO-MB/GCE-based electrochemical immunosensor has an excellent linear relationship with IL-6 ranging from 1 pg/mL to 100 ng/mL, with a limit of detection as low as 0.48 pg/mL. Moreover, our as-prepared sensing strategy shows accurate monitoring of the IL-6 quantity in gingival crevicular fluid samples.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2018
·
IF 5.091
Yiheng Song,Yixing Duan,Li Zhou
Synthesis of adsorbents that simultaneously possess high adsorption performance and convenient separation characteristic remains a big challenge. Herein, we report a viable strategy to prepare hyperbranched polyglycerol (HPG)-based multi-carboxylic magnetic gel (MMG) based on the thiol-ene click chemistry. The obtained HPG-based MMG adsorbent with porous structure and multiple carboxylic groups not only exhibited fast adsorption rate, superior adsorption capacity, and favorable adsorption selectivity towards cationic dyes (e.g., methylene blue (MB) and methyl violet (MV)) but also presented convenient magnetic separation characteristic. The adsorption data showed nice correlation with pseudo-second-order kinetic model and Langmuir isotherm. The optimal adsorption capacity of HPG-based MMG for MB and MV can reach as high as 458.7 and 400.0 mg g −1 , respectively. Moreover, the dye-adsorbed HPG-based MMG could be regenerated in ethanol for reuse without obvious decline of removal efficiency. On the basis of the superior adsorption property of HPG-based MMG, this work offers an effective strategy to prepare advanced adsorbent for dye removal from wastewater.
✓ 已验证
DOI
高影响因子
Journal of Water Process Engineering
·
2025
·
IF 6.7
Dong-Can Lv,Meng-Ru Chen,Mei-Rong Song,Guang-Ce Jiang,Zhi-Min Wang
Conventional understanding of cationic dye adsorption on carbonaceous materials predominantly emphasizes electrostatic attraction. Herein, we report a ball-milled tobacco stem-derived activated carbon (BMTSAC) that exhibits superior adsorption capacity for methylene blue (MB) via a distinct and more resilient mechanism. Ball milling reduced the particle size to 440 nm and increased the specific surface area to 1171.5 m 2 /g, while concurrently modifying the surface chemistry and pore structure that fundamentally shifted the dominant adsorption pathway. The key finding is the dominance of non-electrostatic interactions, namely pore filling and π-π stacking, over electrostatic attraction. This was evidenced by the high MB uptake (520.7 mg/g) under highly acidic conditions (pH = 2.0), far below the point of zero charge (pH PZC = 3.0), and the material's robust performance under high ionic strength. The adsorption process followed the pseudo-second-order kinetic and Langmuir isotherm models, with a maximum adsorption capacity of 776.3 mg/g. The revelation of this mechanism shift underscores the superior potential of BMTSAC for treating complex industrial wastewater where pH fluctuates and ionic strength is high. After 5 cycles, BMTSAC maintained excellent reusability with only a 10.6 % capacity loss, further supporting its strong practical application prospects.
✓ 已验证
产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2026
·
IF 5.2
Xiao-Wen Xu,Hui-Fang Chen,Li-Rong Wu,Bao-Yan Zhang,Fei Peng,Wen-Zhou Zhang,Yan-Li Zheng
o -PD/PVA carbon dots with a protective “polymer armor” were synthesized. • A broad quantitative range (0.1–300 μM) and low LOD (2.4 nM) were achieved for MB. • Intrinsic emission is enhanced by RIR while apparent signal follows IFE. • A digital smartphone platform (B/G ratio) was built for on-site MB monitoring. • High robustness was validated in diverse waters and benchmarked against HPLC. To address the challenges of monitoring methylene blue (MB) across a broad dynamic range in environmental water and industrial wastewater, yellow-emissive carbon dots (CDs) were synthesized from o -phenylenediamine and polyvinyl alcohol (PVA) via a facile one-step solvothermal approach. By leveraging the steric hindrance provided by the long-chain PVA matrix, non-specific probe aggregation in high-concentration environments was effectively inhibited, thereby broadening the dual-stage quantitative range to 0.1–300 μM. Quantitative kinetic investigations revealed a synergistic mechanism of “coexisting apparent quenching and intrinsic enhancement”: the adsorption of MB molecules suppressed non-radiative transitions through spatial confinement effects (quantified by a decrease in k nr ), inducing an anomalous extension of the intrinsic fluorescence lifetime and an elevation in photoluminescence quantum yield. Simultaneously, the substantial spectral overlap integral ( J (λ)) between MB and the CDs triggered a potent inner filter effect (IFE), which dominated the sensitive apparent fluorescence response. The resulting sensing platform demonstrated a segmented linear and semi-logarithmic calibration model across the entire measurement range, achieving a limit of detection (LOD) of 2.4 nM. Furthermore, by integrating a smartphone-based colorimetric algorithm, a self-calibrating sensing system utilizing the B/G ratio was established. Crucially, the analytical reliability and matrix universality were rigorously validated across diverse aquatic sources (domestic tap water, river water, lake water, and naturally contaminated aquaculture wastewater), exhibiting exceptional agreement with independent high-performance liquid chromatography (HPLC) benchmarks (recoveries: 94.0%–104.5%, RSD < 5.9%), which establishes a reliable digital strategy for comprehensive environmental surveillance. Download: Download high-res image (387KB) Download: Download full-size image Molecular-level mechanistic roadmap of the o -PD/PVA probe response toward MB.
✓ 已验证
DOI
高影响因子
Polymers
·
2021
·Vol. 13
·期 10
·1570
·
IF 4.329
Naiku Xu,Mengru Ren
Polytetrafluoroethylene emulsion was ultrasonically mixed with an extremely spinnable poly(acrylic acid-co-hydroxyethyl methacrylate) solution to get a dispersion with good spinnability, and the obtained dispersion was then wet-spun into water-swellable fiber. Crosslinking agents and iron species were simultaneously introduced into the water-swellable fiber through simple impregnation and water swelling. A composite fiber with Fenton reaction-catalyzing function was then fabricated by sequentially conducting crosslinking and sintering treatment. Due to crosslinking-induced good resistance to water swelling and PTFE component-induced hydrophobicity, the composite fiber showed a highly stable activity to catalyze H2O2to oxidatively decolorize methylene blue (MB). Within nine cycles, the composite fiber could decolorize more than 90% of MB within one minute in the presence of H2O2and did not show any attenuation in MB decolorization efficiency. The composite fiber still could reduce the total organic carbon of MB aqueous solution from 18.3 to 10.3 mg/L when used for the ninth time. Therefore, it is believable that the prepared fiber has good and broad application prospects in the field of dye wastewater treatment.Keywords:composite fiber;heterogeneous Fenton catalyst;water-swelling resistance;hydrophobicity;methylene blue oxidative decolorization
✓ 已验证
产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2021
·
IF 4.539
Shumei Zhao,Yingqing Zhan,Qingying Feng,Wei Yang,Hongyu Dong,Ao Sun,Xin Wen,Yu-Hsuan Chiao,Shirui Zhang
Fabrication of highly efficient adsorption and easy-handling absorbent is promising for removal of dyes from wastewater, but it was still a big challenge. In this study, a novel polymer nanofibrous composite absorbent was designed by the decoration of acidified MWCNTs on polydopamine-modified poly(arylene ether nitrile) nanofibrous membrane and following co-deposition of tannic acid/carboxylated chitosan. The structure and composition of as-prepared nanofibrous composite absorbent were confirmed by SEM, FTIR, XPS , and TGA . The congo red (CR) and methylene blue (MeB) were applied as probe dyes to evaluate the adsorption capacity of nanofibrous composite absorbent (With the average pore diameter of 19.21 nm) for cation and anion dyes. It was found that the adsorption capacity of MeB and CR at the optimum pH could reach 633 and 589 mg/g in 300 min, respectively. The adsorption process of MeB and CR followed the Langmuir adsorption model and pseudo-second-order model. Moreover, the nanofibrous composite absorbent exhibited easy-handling property and good regeneration ability, showing the potential application for the efficient adsorption of various dyes from wastewater.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）