Biosensors-Basel
·
2025
·Vol. 15
·期 5
·291
·
IF 5.6
Yawen Zhu,Xuemei Wang,Zhiyong Yan,Feifei Zhang,Jianfei Xia,Lili Lv,Zonghua Wang
The dual-signal output self-calibration mode reduces the false positive and negative signals of electrochemiluminescence (ECL) aptamer sensors. A competitive dual-signal ECL platform was designed for the ultrasensitive detection of kanamycin (KAN) using a zirconium metal–organic framework (Zr MOF) and Luminol as ECL emitters. To enhance the ECL efficiency, a co-reactant (polyethyleneimine, PEI) was covalently bound to the Zr MOF to achieve self-enhanced ECL. Based on the selective interaction between KAN and its aptamer, the Luminol/KAN/Zr MOF-PEI “sandwich” structure was immobilized on the electrode surface. The competition for PEI between emitters increased the Luminol ECL signal and decreased the Zr MOF’s ECL signal. The ratio in ECL signals between the two competitive emitters enabled the quantitative analysis of KAN, achieving a detection limit as low as 7.86 × 10−4ng/mL. This study elucidated the synergistic mechanism between self-enhanced ECL and ECL competition, offering a novel approach for constructing dual-signal ECL sensors using a single co-reactant.
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INORGANIC CHEMISTRY
·
2025
·
IF 4.7
Shufeng Song,Shengxian Wang,Yanming Cui,Wei Xue,Zhixu Long,Hongyang Shan,Nur Chamidah,Kentaro Yamamoto,Masashi Kotobuki,Hao Li,Ning Hu
Designing highly conductive and (electro)chemically stable inorganic solid electrolytes (SEs) from cost-effective precursors is critical for developing all-solid-state batteries (ASSBs). Herein, we report a series of low-cost zirconium (Zr) -based halide nanocomposite SEs, Li1+2xZr1–xTaxO3xCl5–3x (x = 0.33, 0.4, 0.5), synthesized via mechanochemical interaction between LiTaO3 and ZrCl4. The optimized composition, Li1.8Zr0.6Ta0.4O1.2Cl3.8, exhibits enhanced ionic conductivity from 0.46 to 1.12 mS cm–1 and decreased electronic conductivity. Mechanochemical processing modulates the local structural environments of the halide nanocomposites, facilitating ion transport. Combined characterization, including X-ray diffraction, Raman spectroscopy, X-ray photoelectron spectroscopy, and synchrotron X-ray absorption spectroscopy, reveals that oxygen-substituted nanocomposites with distorted local structures are key to improving ion transport. Finally, we demonstrate ASSBs using Li1.8Zr0.6Ta0.4O1.2Cl3.8 as the SE, single-crystalline LiNi0.8Co0.1Mn0.1O2 (scNCM811) as the cathode, and Li–In alloy as the anode, achieving stable cycling at room temperature and 1 C rate.
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SOLID STATE SCIENCES
·
2022
·
IF 3.752
Xuejing Wang,Juan Xu,Sifan Liu,Wenwen Yang,Yanmei Chen,Yanhui Zhang
The research of metal organic frameworks materials of possessing semiconductor performance is important because they show great prospects on applications in wastewater treatment . In the current work, composites of TiO 2 / MOF-801(Zr) was prepared by a wet impregnation at room temperature , and a series of characterizations for catalysts, such as XRD , TEM , XPS, etc was investigated. The results of photocatalytic reduction of Cr(Ⅵ) under simulated solar light irradiation showed that 50%TiO 2 / MOF-801(Zr) exhibited better photocatalytic activity compared with other catalysts, which is attributed to synergistic effect including the interface enhancement effect and the enhancement of photogenerated carriers separation efficiency. The photocatalytic efficiency is as high as 98.1% when adjusting pH of reaction system to 1. It is most likely because the hydrogen cation concentration increased along with the increasing acidity, so that as to the promoting of reduction process of Cr(Ⅵ). In addition, we proposed a possible reaction mechanism of TiO 2 / MOF-801(Zr) composites for photocatalytic reduction of Cr(Ⅵ).
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JOURNAL OF POROUS MATERIALS
·
2023
·Vol. 30
·期 6
·2129-2137
·
IF 2.6
Tao Ruyu,Liu Hao,Xiang Pan,Lin Yichao,Zhou Junjie,Zhou Chen,Zhao Yayun,Tian Ziqi,Zhang Qiuju
Nanoscale Zr-based metal-organic framework (MIP-202) particles were successfully prepared via a seeds-assisted hydrothermal secondary synthesis. The uniformly-shaped MIP-202 particles exhibit excellent performance on selective CO 2 adsorption from CO 2 /CH 4 and CO 2 /N 2 mixtures. At 298 K and 1 bar, the uptake ratios of CO 2 /CH 4 and CO 2 /N 2 of MIP-202 particles are as high as 32.6 and 65.2, respectively. The IAST (ideal adsorbed solution theory)-predicted selectivities of CO 2 /N 2 (50/50, v/v) and CO 2 /CH 4 (50/50, v/v) reach to 4.5 × 10 10 and 102.2, respectively. The breakthrough experiments further demonstrate that the CO 2 /CH 4 and CO 2 /N 2 mixtures can be efficiently separated through an adsorption column packed with MIP-202 particles. In addition, the as-prepared MIP-202 particles had a low iso-enthalpy of adsorption of CO 2 of 32.95 kJ/mol, which is favorable for the regeneration of the adsorbent. Herein the as-prepared MIP-202 is a potential material for efficient separation of CO 2 from CH 4 or N 2 through an energy- and cost-saving CO 2 capture process.
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ANALYTICAL CHEMISTRY
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2020
·
IF 6.785
Weiwei Qiu,Feng Gao,Natsumi Yano,Yusuke Kataoka,Makoto Handa,Weiqiang Yang,Hidekazu Tanaka,Qingxiang Wang
Electrochemical aptasensors involved in chemical labeling are often single-use and sensitivity-limited because the probes are commonly single-point labeled and irreversible. In this work, the specific coordination between Zr4+ and phosphate group (−PO43–) was employed to construct a new aptasensor that is highly sensitive and reusable, using Ochratoxin A (OTA) as the test model. The OTA binding aptamer (OBA) was hybridized with the thiolated supporting sequence (TSS) immobilized on the surface of a gold electrode. The UiO-66 with a formula of [Zr6O4(OH)4(BDC)6], one of the class of Zr metal–organic frameworks (MOFs), was then particularly grafted on the terminal of OBA through the specific coordination between Zr4+ and 5′-PO43–, i.e., the Zr–O–P coordination bond. Similarly, as much as the 5′-PO43– and 3′-methylene blue dual-labeled sequences (DLS) were further assembled on UiO-66 due to the large surface area of MOF and rich active sites of Zr4+. Owing to the specific coordination for signal amplification, the developed aptasensor shows greatly enhanced sensitivity. A wide detection range from 0.1 fM to 2.0 μM and an ultralow detection limit of 0.079 fM (S/N = 3) for OTA were obtained. Additionally, the TSS can rehybridize with a new OBA to regenerate the aptasensor but without complicated pretreatments, enabling a aptasensor that is readily reusable for OTA detection. The aptasensor was successfully applied for OTA detection in the red wine samples, demonstrating a promising prospect for food safety monitoring.
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JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
·
2015
·
IF 2.947
Xiaowei Chi,Zhaoyin Wen,Jingchao Zhang,Yu Liu
A novel hybrid route, combining simple co-precipitation and conventional solid state reaction, is proposed for the first time to synthesize BaCe 0.4 Zr 0.4 Y 0.2 O 3− δ powders at a temperature as low as 1150 °C. This temperature is much lower than that used for conventional solid state reaction method and even comparable to that used in sol–gel route. The reasons for the low calcination temperature are analyzed in detail from the macroscopic to microscopic viewpoints. Moreover, with the powders made by the novel method, dense ceramic could be easily obtained. Further, impedance data illustrated that its electrical conductivity in wet H 2 at 750 °C is up to 1.39 × 10 −2 S/cm, which is the highest among all the samples prepared by the three different methods and much higher than the reported results related to BCZY proton conductors . Also, the new method is particularly suitable for other multi-component oxides .
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Nature Communications
·
2026
·
IF 18.1
Li Zongnan,Mu Yongbiao,Xia Yuxun,Yang Ting,Yan Zhepei,Li Yafeng,Guo Longyuan,Zeng Lin,Sun Xueliang,Wei Mingdeng
The pursuit of high-energy-density all-solid-state lithium batteries necessitates integration with next-generation high-voltage positive electrodes. However, a critical challenge lies in the intrinsic instability of most highly ionically conductive solid electrolytes, which decompose at potentials above 4.30 V vs Li + /Li, resulting in severe interfacial degradation and increased impedance. Here, we show that an amorphous Li 2 Zr 0.625 Ta 0.3 Cl 4.2 O 0.9 halide electrolyte, synthesized via a non-equimolar cation-anion amorphous engineering strategy based on Li 2 ZrCl 6 , effectively overcomes this limitation. With a high ionic conductivity of 4.11 mS cm −1 at 25 °C, it enables stable high-potential cycling through kinetically stabilized operation mediated by a self-passivating positive electrode–electrolyte interphase. When paired with LiNi 0.88 Mn 0.06 Co 0.06 O 2 positive electrode and a Li-In alloy negative electrode, the cells retain up to 81.2% of the initial capacity after 2,000 cycles at 10 C under cell cutoff voltages of 4.18 V (corresponding to 4.80 V vs Li⁺/Li). Overall, non-equimolar cation–anion amorphous engineering enables conductive, high-voltage-tolerant Zr-based halides for all-solid-state lithium batteries.
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Scientific Reports
·
2024
·Vol. 14
·期 1
·1-13
·
IF 3.8
Bu Daolu,Yang Hu,Zhang Haibo,Wang Liang,Wang Jiao,Liao Jie
The present study investigates the efficacy of newly developed Zr-based metal–organic frameworks, specifically MIP-206, and its amine-modified counterpart, MIP-206-NH 2 , for the re-covery of antimony (Sb) from both synthetic and actual mining wastewater. Batch method studies were employed to examine the effect of waste media pH, Sb concentration, process kinetics, and the performance of the regeneration solution. MIP-206-NH 2 exhibited impressive separation capabilities, achieving 102.18 mg/g and 63.23 mg/g for Sb (V) and Sb (III), respectively. In contrast, the pristine MIP-206 reached maximum values of 26.26 mg/g for Sb (V) and 16.95 mg/g for Sb (III). The separation process was well-described by the Langmuir equation, and the kinetics followed the pseudo-second-order model. Although the amine modification resulted in a decrease in the surface area of MIP-206 from 1345.21 to 1169.86 m 2 /g, SEM and XRD analyses confirmed that the structural integrity of MIP-206-NH 2 remained unchanged. In terms of reusability, MIP-206-NH 2 maintained up to 90% of its separation performance over 9 cycles, while MIP-206 demonstrated effectiveness for 7 cycles. The regeneration solution exhibited a capacity of approximately 0.63 mol/L for Sb (V) and 0.71 mol/L for Sb (III). Furthermore, MIP-206 and MIP-206-NH 2 demonstrated successful application in selectively separating Sb from real mining wastewater.
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Biofabrication
·
2025
·Vol. 17
·期 3
·035012
·
IF 8
Mengyuan Li,Jiaming Ge,Jingwen Yao,Yuanhao Zhang,Lin Ma,Zheng Li,Xiangli Han,Ming Liu,Fei Tian,Jing Zhao
Oral squamous cell carcinoma (OSCC) is the most common malignant tumor in the head and neck. Due to low bioavailability and passive targetability of anticancer drugs show great limitations in cancer therapy, the treatment of OSCC faces major challenges. Folic acid (FA) targeting can deliver anticancer drugs efficiently into the tumor environment, further enhance the anti-cancer efficacy. Herein, the nanoplatform based on UiO-66 that encapsulated with an effective FA targeting ligands and the pH-responsive polyethylene glycol (PEG) layer for the targeted delivery of berberine (Ber) is constructed for fighting against OSCC. The FA modification and controlled pH-responsiveness enable the targeted delivery of UiO-66/PEG-FA, which promotes the release of Ber and increases the cumulative intracellular Ber concentration, which both promote consumption of glutathione (GSH) and induced generation of reactive oxygen species (ROS), further stimulate the secretion of inflammatory factors (TNF-α and IL-1β). A comprehensive evaluation of in vitro and in vivo experiments show that UiO-66@Ber/PEG-FA promote autophagy and apoptosis of tumor cells by regulating the expression of Beclin-1, ATG13, BAX and Bcl-2, and effectively inhibit tumor growth. Overall, UiO-66@Ber/PEG-FA exhibit superior pH-responsiveness and targeted therapeutic efficiencies in vitro and vivo, it can serve as an approach for OSCC therapy.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Yue Wang,Xiangyan He,Qi Zhang,Ling Luo,Tianping Lv,Xiuwu Wang,Junhua Zhang
Construction of highly efficient catalysts is crucial for the catalytic transfer hydrogenation (CTH) of bio-based carbonyls to valuable chemicals and fuels. Herein, we successfully synthesized a series of uniformly dispersed Zr(OH) 4 -Fe 3 O 4 nanoparticles with the regulation of sodium dodecyl benzene sulfonate (SDBS), which exhibited exceptional activity for the CTH of furfural (FAL) into furfuryl alcohol (FOL). Systematic characterizations revealed that SDBS effectively modified the interaction between Fe 3 O 4 and Zr(OH) 4 , thereby enhancing Lewis acidity by facilitating the construction of electron-deficient zirconium sites. Meanwhile, the presence of oxygen vacancies and surface hydroxyl groups in Zr(OH) 4 -Fe 3 O 4 -SDBS facilitated the adsorption and activation of both substrate and hydrogen donor. Thanks to these synergistic effects, a complete conversion of FAL with an impressive selectivity towards FOL was achieved, with a remarkable turn-over frequency value reaching as high as 42.5 h −1 . Encouragingly, Zr(OH) 4 -Fe 3 O 4 -SDBS also demonstrated its universality in the CTH of carbonyl compounds by exhibiting remarkable separation capability while maintaining its activity and structure after being reused for 11 cycles without significant changes.
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CHINESE JOURNAL OF CHEMICAL ENGINEERING
·
2021
·
IF 3.171
Yongde Ma,Rengan Liang,Wenquan Wu,Jiayin Zhang,Yanning Cao,Kuan Huang,Lilong Jiang
Developing catalysts with not only hydrogenation activity but also cracking activity is very important for the advancement of suspended-bed hydrocracking technology. Within this respect, MoS 2 /SiO 2 -Al 2 O 3 bifunctional catalyst is a kind of typical catalysts with both hydrogenation and cracking activity. Herein, a series of Zr-doped SiO 2 -Al 2 O 3 mixed oxides were synthesized by a sol-gel coupled with hydrothermal method. The synthesized mixed oxides were characterized for chemical structures and acidic properties. It is found that doping SiO 2 -Al 2 O 3 with Zr atoms significantly increases the numbers of acidic sites. The Zr-doped SiO 2 -Al 2 O 3 mixed oxides were then combined with dispersed MoS 2 , which was in-situ produced from oil-soluble Mo precursors, to fabricate a novel kind of bifunctional catalysts for suspended-bed hydrocracking of heavy oils. Owing to the significantly increased numbers of acidic sites in Zr-doped SiO 2 -Al 2 O 3 mixed oxides, corresponding bifunctional catalysts demonstrate much enhanced activity for suspended-bed hydrocracking of heavy oils in relative to MoS 2 /SiO 2 -Al 2 O 3 bifunctional catalysts.
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Materials Today Communications
·
2023
·
IF 3.8
Jingxin Tian,Hongjun Zhang,Liwei Zhang,Dongliang Wang,Yong Huang,Elena Balashova,Boris Krichevtsov,Hua Ke
The effects of oxygen vacancies on electric properties of high valence ions (Mo/Zr/Ti) doped Bi 0.85 Nd 0.15 FeO 3 (marked as BNFM, BNFZ, BNFT) ceramics with morphotropic phase boundary (MPB) are investigated. MPB structures consisting of rhombohedral, intermediate and orthorhombic phases exist in all samples, which is confirmed by the XRD Rietveld refinements and TEM analyses. The BNFT has the maximum remnant polarization of 34.5 μC/cm 2 at 180 kV/cm, owing to its lowest paraelectric orthorhombic phase content. XPS and impedance results reveal that the BNFT ceramic has the relatively low oxygen vacancy contents and the largest impedance value, which is beneficial for the ferroelectric test. The best comprehensive properties of BNFT open wide prospects for improving BiFeO 3 -based ceramics.
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