Biomaterials Advances
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2025
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IF 6
Ying Sun,Yining Cai,Shanshan Xu,Ningning Zhai,Zirui Wang,Zongpu Qiu,Shuying Han,Yuanqing Wei,Rui Liu,Hao Wu
While the regulatory roles of biomaterial topology in bone regeneration are recognized, the specific osteogenic mechanisms driven by distinct morphological features, particularly without biochemical cues, remain poorly understood. This study aimed to independently elucidate the osteogenic potential and underlying mechanisms solely attributable to the distinctive “S”-grooved topology derived from cuttlebone. Inspired by cuttlebone, we successfully fabricated a biomimetic polycaprolactone (PCL) membranes sheet with “S”-grooved topology using liquid silicone mold replication combined with PCL recasting techniques. Comprehensive characterization (SEM, CLSM) confirmed precise replication of the native “S”-grooved morphology (width: 100 ± 30 μm, depth: 20 ± 6 μm). In vitro studies revealed that these grooves promoted directional adhesion and proliferation of rat bone marrow mesenchymal stem cells (rBMSCs) via contact guidance, as evidenced by cytoskeleton alignment. Furthermore, the “S”-grooved topology significantly enhanced osteogenic differentiation of mouse pre-osteoblasts (MC3T3-E1), demonstrated by increased alkaline phosphatase (ALP) activity and mineralized nodule formation. Mechanistic investigations using RT-qPCR, Western blot, and dimethyl labeling-based quantitative proteomics on rBMSCs identified key involvement of the Rap1-ERK signaling pathway. Specifically, the “S”-grooved topology upregulated Rap1 expression and enhanced ERK phosphorylation, leading to increased expression of osteogenic markers (e.g., Runx2, OPN). These findings demonstrate that the biomimetic “S”-grooved topology alone, through contact guidance and activation of the Rap1-ERK mechanotransduction pathway, significantly enhances osteogenic differentiation, providing a foundation for designing topologically optimized biomaterials for bone regeneration biomimetic PCL membranes sheet with the “S”-grooved topology.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2025
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IF 9.7
Hong Fan,Lili Ai,Mengjiao Xu,Shumin Wu,Luxiang Wang,Chuan Tan
Photocatalytic synthesis of hydrogen peroxide is an emerging topic for solar-to-chemical energy conversion. ZnIn 2 S 4 /Bi 4 Ti 3 O 12 (ZIS/BTO) - based S-scheme heterojunction semiconductor photocatalysts were prepared via a one-pot water bath method. Under visible light irradiation, the optimum H 2 O 2 yield of ZIS/BTO-2 reaches 1102 µmol L −1 , which is 20.0 and 11.5 times higher than those of the pure phases of Bi 4 Ti 3 O 12 and ZnIn 2 S 4 , respectively. Experimental and density functional theory (DFT) calculations demonstrated that the Built-in Electric Field (IEF) present between the ZIS/BTO S-type heterostructures not only facilitated the transfer of photogenerated carriers to surface active sites, but also promoted the adsorption of molecular oxygen and the tuning of the energy band structure. This resulted in an enhancement of the efficiency of photocatalytic oxygen reduction reaction (ORR) and the water oxidation reaction (WOR) for the synthesis of H 2 O 2 . Hence, the present study provided a practical route for the efficient synthesis of H 2 O 2 over Bi 4 Ti 3 O 12 - based photocatalysts and disclosed the reaction mechanism, that is, a heterojunction with a high efficiency for H 2 O 2 synthesis.
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Green Synthesis and Catalysis
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2025
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IF 6.3
Mengqian Song,Yu Li,Jinhui Feng,Shuhong Mao,Peiyuan Yao,Qiaqing Wu,Dunming Zhu
Chiral β-amino alcohols represent a significant structural motif in many biologically active molecules. Developing an efficient biocatalytic method for synthesizing chiral β-amino alcohols with structural diversity is highly desirable. In this study, enzymatic hydroxymethylation of aryl-aliphatic aldehydes by benzaldehyde lyases (BALs) enabled the synthesis of α-hydroxymethyl ketones at high substrate loadings (200 mmol/L - 300 mmol/L). And the reductive amination of diverse α-hydroxymethyl ketones by amine dehydrogenases (AmDHs) was conducted for synthesizing chiral β-amino alcohols in high isolated yields (60 %-79 %). Furthermore, a one-pot, two-step enzymatic process involving BAL-catalyzed hydroxymethylation of aldehydes and subsequent AmDH-catalyzed reductive amination was developed, enabling the synthesis of aromatic, aliphatic and aryl-aliphatic ( S )-β-amino alcohols from corresponding aldehydes in good to excellent isolated yields (56 %-96 %) and excellent enantioselectivity (>99 % ee ). The practical utility of this methodology was further demonstrated through the synthesis of key intermediates for antiviral drug Telaprevir or ATP competitive ERK inhibitor BVD-523.
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TRIBOLOGY INTERNATIONAL
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2024
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IF 6.1
Lulu Tian,Yuanping Huang,Chaoran Li,Shuang Chen,Jiayu Peng,Liyong Niu,Zhijun Zhang
Complex operating conditions pose greater challenges for lubricants, making the development of multi-functional additives a trend. This research introduces a multifunctional Cu-Mo-S nanoparticle (CMS) additive, synthesized using a unique one-pot in situ method. The CMS significantly improved the tribological performance and oxidation stability of base oils. Specifically, 0.5 wt% CMS manifested a remarkable reduction in the friction coefficient and wear volume of ester-based oils by 74.75% and 95.91%, accompanied by a noteworthy increase in the extreme pressure capabilities exceeding 50%, outperforming the individual copper nanoparticles, organic molybdenum, and their mixtures. The remarkable results are attributed to the distinctive structure of CMS, which decomposed during the friction process, forming a continuous friction film containing copper, molybdenum, and iron compounds.
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CHEMOSPHERE
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2024
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IF 8.1
Qi Chen,Ling Hu,Yingzhang Shi,Cheng Liu,Yidong Hou,Jinhong Bi,Jimmy C. Yu,Ling Wu
Heterogeneous photocatalytic degradation of antibiotic involves the activation of antibiotic molecules and the photocatalytic oxidation process. However, the simultaneous improvement of these processes is still a challenge. Herein, S-scheme heterojunctions consisted of Cu 2 O nanocluster with defective WO 3 nanosheets were constructed for efficient photocatalytic degradation of levofloxacin (LVX). The typical CNS-5 composite (5 wt% Cu 2 O/WO 3 ) achieves an optimal LVX degradation efficiency of 97.9% within 80 min. The spatial charge separation and enhancement of redox capacity were realized by the formation of S-scheme heterojunction between Cu 2 O and WO 3 . Moreover, their interfacial interaction would lead to the loss of lattice oxygen and the generation of W 5+ sites. It is witnessed that the C–N of piperazine ring and C O of carboxylic acid in LVX are coordinated with W 5+ sites to build the electronic bridge to activate LVX, greatly promoting the further degradation. This work highlights the important role of selective coordination activation cooperated with S-type heterojunctions for the photocatalytic degradation and offers a new view to understand the degradation of antibiotics at molecular level.
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MATERIALS SCIENCE IN SEMICONDUCTOR PROCESSING
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2025
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IF 4.6
Rongrong Yu,Jingjing Wang,Xinyu Zhi,Danyi Yang,Yongqi Zhao,Guifeng Chen,Chengchun Tang,Yi Fang
With growing concerns about antibiotic contamination in water environments, developing efficient photocatalysts for tetracycline (TC) degradation has become imperative. In this study, a novel nanoflower-like BiOI/UiO-66(Ce/Fe) S-scheme heterojunction photocatalyst was developed for efficient TC degradation under visible light. Experimental evaluations revealed that the optimized 0.05-Bi/U(Ce/Fe) sample achieved 99.5 % TC degradation efficiency, maintaining 88.8 % of its initial activity after four consecutive cycles. The superior photocatalytic activity arises from three synergistic mechanisms: Fe 3+ doping modulates the band structure to broaden visible-light absorption, while the synergistic effect of Ce 4+ /Ce 3+ and Fe 3+ /Fe 2+ redox pairs optimizes charge transport. The internal electric field at the BiOI/UiO-66(Ce/Fe) heterojunction enhances charge separation while maximizing the redox capacity of the photocatalyst. Radical capture experiments and LC-MS analysis confirmed ·O 2 − and ·OH as the dominant reactive radicals, with proposed possible degradation pathways. Thus, a new synergistic strategy for designing efficient photocatalysts is proposed in this work.
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NEW JOURNAL OF CHEMISTRY
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2025
·Vol. 49
·期 24
·10261-10267
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IF 2.5
Fangyuan Fan,Chunlin Teng,Rongjin Zhu,Lina Zhu,Lingfei Xu,Yeshuang Du
Electrochemical water-splitting is a potential “green” approach to produce a large amount of hydrogen. However, its half reaction, the oxygen evolution reaction (OER), suffers sluggish dynamics and huge overpotential. This encumbers the energy conversion efficiency from electric energy to hydrogen energy, resulting in cost increases. Besides, rare metal catalysts such as RuO2 and IrO2 have high OER catalytic activity but they are low in reserve and expensive. Hence, exploration of highly efficient, stable and cheap transition metal-based electrocatalysts to speed up the OER rate is a rational approach. Herein, S-doped NiFe2O4@NiSe2 nanospheres supported on nickel foam were synthesized through a simple one-pot hydrothermal method. Thanks to the unique structure, large surface area, numerous active sites, incorporation of S-anion atoms and synergistic effect between different components, S-doped NiFe2O4@NiSe2 nanospheres showed extraordinarily efficient electrocatalytic activity towards the OER in alkaline medium. When the current density was 10 mA cm−2, the OER overpotential was 190 mV. Meanwhile, it exhibited excellent long-term stability and was maintained at 10 mA cm−2 for ≥94 h in a chronopotentiometry test.
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Coatings
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2025
·Vol. 15
·期 6
·630
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IF 2.8
Zhaobin Lu,Baoxin Wang,Shengtao Li,Feiyan Pan,Xuewei Zhu,Xiaofeng Wei
In the “dual carbon” objective, the preparation of non-precious metal catalysts with low cost and high activity is essential for the study of hydrogen evolution reactions (HERs). This study employed biomass pomelo peel powder as the carbon source and ammonium metatungstate (AMT) as the tungsten source and, through a facile one-step method in molten salt, fabricated a biomass carbon-based nanocatalyst featuring carbon flakes adorned with tungsten carbide (WC) nanoparticles. Dicyandiamide and cysteine were introduced as nitrogen and sulfur sources, respectively, to explore the impacts of N-S elemental doping on the structure, composition, and HER performance of the WC/C catalyst. The experimental results showed that N-S doping changed the electronic structure of WC and increased the electrochemically active surface area, resulting in a significant increase in the HER activity of WC/C@N-S catalysts. The WC/C@N-S catalyst was evaluated with hydrogen evolution performance in a 0.5 mol/L H2SO4solution. When the cathodic current density reached 10 mA/cm2, the overpotential was 158 mV, and the Tafel slope was 68 mV/dec, underscoring its excellent HER performance. The outcomes offer novel insights into the high-value utilization of agricultural biomass resources, and pave the way for the development of cost-effective, innovative hydrogen evolution catalysts.
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APPLIED SURFACE SCIENCE
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2025
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IF 6.9
Ning Chen,Dong Yang,Zi-Long Zhang,Jun-Hui Su,Wen-Yu Yang,Fu Li,Guang-Xing Liang,Jing-Ting Luo,Yue-Xing Chen,Zhuang-Hao Zheng
Flexible thermoelectric (TE) materials are promising candidates for powering wearable electronics and self-sustained microdevices. Here, we report the synthesis of S-doped Bi 2 Te 3 flexible thin films (f-TFs) on polyimide (PI) substrates via a two-step method combining physical vapor deposition and subsequent thermal diffusion. Sulfur incorporation effectively substitutes Te in the Bi 2 Te 3 lattice, leading to lattice contraction and a moderate increase in carrier concentration. Structural analyses reveal that S doping shortens the Bi–Te/S bonds and weakens interlayer van der Waals interactions, facilitating strain relaxation through nanoscale slip. As a result, the 3.8 % S-doped film achieves a peak power factor of 14.8 μW cm −1 K −2 at 300 K and exhibits moderate electrical-conductivity stability under repeated bending, with resistance variation below 10 % after 1000 cycles. These findings demonstrate that thermal diffusion-driven compositional tuning provides a practical approach to enhancing both thermoelectric performance and mechanical flexibility in Bi 2 Te 3 -based f-TFs.
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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2025
·Vol. 27
·期 1
·434
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IF 4.9
Mingyuan Zhang,Jinru Wang,Caihan Zhu,Yuning Zhang,Dewei Li,Shuozhen Hu
Developing efficient and durable oxygen reduction reaction (ORR) catalysts is crucial for advancing fuel cell technology and sustainable energy conversion. In this study, a scalable strategy was employed to synthesize ZIF-derived nitrogen-sulfur co-doped carbon nanosheets embedded with in situ generated ZnS and Co9S8nanoparticles. The synergistic effect of heteroatom doping and metal sulfide modification effectively modulated the electronic structure, optimized charge transfer pathways, and enhanced structural stability. The optimized catalyst exhibited a half-wave potential of 0.83 V vs. RHE, close to that of commercial 20 wt% Pt/C (0.85 V), excellent 4e−ORR selectivity, and exceptional stability, with only a ~15 mV degradation after 10,000 cycles. These results demonstrate that the combination of nitrogen sulfur co-doping and in situ metal sulfide addition pro-vides an effective approach for designing highly active and durable non-precious metal catalysts for the ORR. This synthetic concept provides practical guidance for the scalable preparation of multifunctional nanomaterial-based catalysts for electrochemical energy applications.
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PEST MANAGEMENT SCIENCE
·
2025
·
IF 3.8
Juncheng Wu,Zhengyuan Tao,Jingyi Cao,Wei Hu,Minghao Jiang,Yahui Li,Haiqun Cao,Min Liao,Ning Zhao
BACKGROUND Rice flatsedge ( Cyperus iria L.) is one of the most troublesome weeds infesting rice fields across China. Bensulfuron-methyl, an acetolactate synthase (ALS)-inhibiting herbicide, has been widely used for the control of Cyperaceae weeds in rice production. However, long-term and extensive use of this herbicide has resulted in the evolution of resistant C. iria populations. In this study, a suspected bensulfuron-methyl-resistant (R) population collected from a rice field that survived field-recommended applications was investigated to elucidate its resistance level and underlying mechanism. RESULTS Compared with a susceptible (S) population, the R population exhibited a high level of resistance to bensulfuron-methyl [resistance index (RI) = 12.88] and cross-resistance to metazosulfuron (RI = 11.66), bispyribac-sodium (RI = 9.10) and penoxsulam (RI = 6.35). No mutations were detected in the ALS gene, and ALS expression levels did not differ significantly between the R and S plants. Pretreatment with the cytochrome P450 inhibitor malathion and the glutathione S -transferase inhibitor 4-chloro-7-nitrobenzoxadiazole effectively reversed bensulfuron-methyl resistance in R plants. Liquid chromatography tandem mass spectrometry analysis showed that the R plants metabolized bensulfuron-methyl significantly faster than the S plants. RNA sequenccing analysis revealed remarkable upregulation of CYP97A3 and GSTF1 in the R population, while molecular docking indicated strong binding affinities between both enzymes and bensulfuron-methyl at their active sites. CONCLUSION These results reveal that enhanced expression of CYP97A3 and GSTF1 may contribute to bensulfuron-methyl resistance in C. iria , highlighting the role of metabolic detoxification in the evolution of non-target-site resistance in this species. © 2025 Society of Chemical Industry.
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Journal of Energy Chemistry
·
2022
·
IF 13.599
Qinhua Gu,Yujie Qi,Wuxing Hua,Tongxin Shang,Junnan Chen,Luozhen Jiang,Lina Li,Ming Lu,Yixiao Zhang,Xi Liu,Ying Wan,Bingsen Zhang
The shuttle effect caused by soluble lithium polysulfides (LiPSs) deteriorates multiphase transformation reaction kinetics of sulfur species, and gives rise to an unserviceable lithium-sulfur (Li-S) battery. Catalysis, as a process optimization approach, offers an option to eliminate the intrinsic issues. However, exploring and understanding the role of catalysts on electrode reaction remains critical bottlenecks, particularly as they are prone to continuous evolution under complex dynamic environment. Herein, platinum nanoparticles loaded on MXene nanosheets, as sulfur host, and the action of catalysts on the reaction process are investigated via ex-situ monitors upon solid–liquid–solid chemical transformation of sulfur species. These traces confirm that the high performance originates from electron transfer between catalysts and LiPSs, which lowers the nucleation barrier from liquid LiPSs to solid Li 2 S/Li 2 S 2 . Further, the accelerated liquid–solid conversion can alleviate the accumulation of LiPSs, and boost the reaction kinetics in Li-S batteries. The findings corroborate the electronic modulation between catalysts and LiPSs, which is a generalizable strategy to optimize energy conversion efficiency of Li-S batteries.
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