Peptide Science
·
2023
·
IF 2.4
Qianyu Zhang,Hongjing Chen,Huali Chen
PASylation has been recently reported as a feasible alternative to PEGylation, which in essence is using polypeptides constituted of a combination of proline, alanine and serine for the hydrophilic modification of pharmaceuticals. In this work, we focused on the biocompatibility evaluation of two PAS peptides, (PAS) 8 and (PA 3 ) 7 as well as the more frequently used polymers polyethylene glycol (PEG) and polyglycerol (PG). It has been verified in this study that (PAS) 8 and (PA 3 ) 7 both exhibited low cell toxicity against HUVEC and RAW 264.7 cell lines. They also showed negligible RBC hemolysis and agglutination, which demonstrated adequate hemocompatibility. Their potential interactions with bovine serum albumin have also been investigated, and the results indicated little hydrophobic interactions between the polymers and protein. In conclusion, (PAS) 8 and (PA 3 ) 7 as well as PEG and PG all showed considerable compatibility and safety in these studies, suggesting that (PAS) 8 and (PA 3 ) 7 could be considered as potential candidates for PEG replacement in future studies. Graphical
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CARBON
·
2022
·
IF 11.307
Dengji Xu,Que Huang,Likai Yang,Yanjun Chen,Zhumao Lu,Huijuan Liu,Peijie Han,Li Guo,Chao Wang,Changcheng Liu
Based on the broad scope of applications in electronics, the development requirements of excellent electronic packaging materials with efficient thermal management performance and high electromagnetic interference shielding effectiveness (EMI SE) are critical, while which are also hardly compatible for a single material such as an elementary substance or a simple chemical compound. Therefore, a series of novel composites filled with phase change material (PCM) polyethylene glycol (PEG) were developed with MXene as the skeleton, and flame retardant Mg(OH) 2 was added to achieve flame retardancy for composites under high temperature environment. As a result, the prepared MXene@PEG/Mg(OH) 2 in this work could achieve an excellent EMI SE of 38.8 dB in X-band, and the thermal conductivity rose from 0.26 to 0.95 W/m·K, while the composite film also presented certain mechanical properties , with the latent heat of 153.72 J/g. Furthermore, the shape stability of the composite material was favourable due to the capillary function of MXene, which effectively forbade the leakage behavior of PCMs during solid-liquid phase transition. The design of MXene@PEG/Mg(OH) 2 composite with stable structure provided a new idea for manufacturing EMI SE materials which often exposed to electromagnetic radiation, which indicated potential great significance for a new generation of packaging materials application in electronic equipment field.
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CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Ying Yang,Dongcheng Ren,ChunLi Shang,Zhongzhen Ding,Xinruo Luo
Direct conversion of cellulose to high yield 1,2-propylene glycol (1,2-PG) is amazing in the biomass valorization to diols, since this process is atom-economic, carbon neutral, and the produced 1,2-PG has a large market demand. However, it is very challenging to control cellulose hydrogenolysis owing to high reactivity of intermediates (like glucose) and metal-acid repelling, leading to decreased selectivity of metal-acid multi-functional catalysts. Aimed at this, we herein developed a highly selective metal-acid catalyst (Ru/NC@void@MC-SO 3 H) with site isolated Ru clusters (1.4 nm) on the core and sulfoacids on the shell in a yolk-shell nanoreactor by a layer-by-layer assembly before chemical transformation. The spatial isolation of metal and acid sites integrated in a mesoporous yolk-shell nanoreactor not only facilitates the metal-acid synergism in hydrolysis, isomerization/hydrogenolysis and hydrogenation cascade reactions, but also provides a designated diffusion pathway that is favorable for reaction species. As expected, the elaborately fabricated Ru/NC@void@MC-SO 3 H proves to be highly selective to 1,2- PG (38 % yield), delivering a productivity of 342.86 mol h −1 g Ru –1 and an extremely high turnover number of 173264, outperforming the state-of-art metal-acid catalysts for cellulose hydrogenolysis to 1,2-PG. Our characterization and performance test suggest that sulfoacids are mainly responsible for cellulose hydrolysis, while N -stabilized Ru centers contribute to the glucose isomerization to fructose and its further hydrogenolysis to dihydroxyacetone, followed by hydrogenation to 1,2-PG on metallic Ru species. The acidity and basicity optimized for site isolated Ru/NC@void@MC-SO 3 H is beneficial to balance intermediate reactions, rendering a higher selectivity to target 1,2-PG. The concept illustrated in this study will provide a guide for the development of other site isolated multi- functional catalysts towards cellulosic biomass conversion and other cascade reactions.
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Food & Function
·
2022
·Vol. 13
·期 20
·10476-10490
·
IF 6.317
Ju Wang,Lei Wang,Shengnan Shi,Yaqi Cao,Junmei Feng,Changhong Liu,Lei Zheng
Probiotic-based therapy is a promising approach, which can positively modulate bacterial composition and maintain homeostasis. However, exogenous probiotics are easily destroyed by harsh conditions in vivo; thus, their application prospects have been severely limited. Specifically, oxytetracycline (OTC), a broad-spectrum antibiotic widely used in aquaculture, results in adverse intestinal environments, such as dysbacteriosis, oxidative damage, and gut dysmotility. Here, we describe a facile method to apply glycol chitosan/alginate as armor on the surface of probiotics to effectively protect them from the changed enteric environments induced by OTC. The results demonstrated that the coated Lacticaseibacillus rhamnosus GG (LGG) for only 2 h administration could significantly improve the colonization rate of LGG, and the relative abundance of Lacticaseibacillus can reach 80% in OTC-treated larvae intestines. We also explored the specific mechanisms of the coated LGG to diminish reactive oxygen species (ROS) generation and rescue gut dysmotility for OTC treatment, including enhancing the activity of antioxidative enzymes (CAT, SOD and GPx) and increasing 5-HT synthesis. The mitigation effect of the coated LGG for 2 h administration was comparable to that of uncoated LGG for 24 h administration. Encapsulation of LGG with polysaccharides provides a unique application example for generating useful bacterial therapeutics in harsh intestinal environments.
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PubMed
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2022
·
IF 8.025
Yimei Yang,Tian Hu,Hongyan Zhang,Bu-Ning Liu,Jinwen Liu,Wei-Xiong Li,Kui Song,Gang-Biao Jiang
The mechanical mismatch between soft hydrated tissues and sutures has become a common negative impact on wound healing process. A novel method of coating multilayer polymer shells is thus reported to improve the mechanical performance of hydrogel sutures. It is suitable for tissue patching and shows advantages of convenient, efficient, and biosafety. Specifically, a precursor hydrogel (Cu@CMC) consisted of carboxymethyl chitosan and copper modified by carbon dots was used as the inner sheath, and then bonding the precursor hydrogel sheath with toughening polyethylene glycol network by anchoring sites composited from rigid chitosan shell integrated a whole structure. Subsequently, the whole system was soaked with EtOH, and rapid dehydration of EtOH was used to accelerate the entanglement process between the two coatings by constricting the molecular chains. Finally, an ideal suture (Cu-fiber) with both toughness and rigidness was obtained. The data showed that the tensile strength and biosafety of the hydrogel sutures prepared by the new strategy were significantly improved, and the skin, liver and vessel of rodents can be sutured without secondary damage. Moreover, it can inhibit inflammation response and promote the healing process of skin wound, indicating that the Cu-fiber will become a great candidate for tissue patching.
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PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2022
·Vol. 139
·期 43
·e53067
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IF 3.057
Qiang Yang,Jing Guo,Sen Zhang,Fucheng Guan,Yue Yu,Qiang Yao,Xin Zhang,Yi Xu
Due to biocompatibility and similar extracellular matrix structure, polyvinyl alcohol (PVA)/polyethylene oxide (PEO) nanofiber membranes are an essential medical dressing. However, the phase separation of the PVA/PEO composite system will occur within a short time. It severely limits the continuous preparation of PVA/PEO nanofiber membranes. To make PVA/PEO composite system maintain compatibility, a novel polyvinyl alcohol-allyl polyethylene glycol (PVA-g-APEG) graft copolymer with phase change, compatibilization and biocompatibility was prepared successfully. Fourier transform infrared (FTIR) and nuclear magnetic resonance (NMR) prove that the copolymerization and alcoholysis reaction allyl polyethylene glycol (APEG) and vinyl acetate (VAc) successfully obtained PVA-g-APEG graft copolymer. The prepared PVA-g-APEG not only has electrospinability but can effectively prevent the phase separation of PVA/PEO composite system, which ensures the continuity of electrospinning in the industry. Additionally, the feasibility of the PVA-g-APEG compatibilized PVA/PEO composite system for application in biomedical was verified through the preparation and various assessments of PVA-g-APEG/PVA/PEO nanofiber dressings. The prepared PVA-g-APEG is beneficial to the PVA/PEO composite system to broaden its application in biomedical and other fields.
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JOURNAL OF MEMBRANE SCIENCE
·
2022
·
IF 10.53
Weilin Zhang,Gen-Liang Ji,Jianqiang Wang,Yingyao He,Li Liu,Fu Liu
Nanofiltration (NF) membrane fouling is still an inevitable main challenge, which leads to the reduction of membrane performance. The large number of aliphatic chains in the poly (vinyl alcohol) (PVA) skeleton will reduce the increase in hydrophilicity. Therefore, the existing PVA grafting technology has certain limitations in the application of anti-fouling modification. A facile and effective strategy for enhancing membrane surface hydrophilicity and antifouling performance becomes very important. In this study, epoxy derived polyethylene glycol crosslinking network was in situ introduced on polyamide nanofiltration membrane through ring-opening reaction of poly(ethylene glycol) diglycidyl ether (PEGDGE) to enhance membrane hydrophilicity and antifouling performance. The large amount of ether units in PEGDGE endowed this crosslinked network with hydrophilicity and relative loose structure. Results of FTIR, XPS and WCA indicated that PEGDGE-polyether crosslinking network was successfully formed on the surface of the NF membrane. Water contact angle of the modified membrane was decreased to 23.7 ± 1.2° compared with pristine NF membrane (45.7 ± 2.1°). For the performance test, humic acid (HA) was used to evaluate the fouling resistance of membranes. FRR (Flux Recovery Ratio) value was as high as 91% (e.g., NF–10 S membrane) compared with the pristine membrane (71%). Meanwhile, NF–10 S membrane showed lower FDR (Flux Decline Ratio) (41%) than the pristine NF membrane (68%). Both the low FDR and high FRR of NF–10 S membranes indicated an excellent long-term anti-fouling property. The coating can provide a large number of ether bonds to improve hydrophilic properties, and the proposed strategy in the current study can offer a facile and effective method for membrane antifouling modifications.
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高影响因子
WOOD SCIENCE AND TECHNOLOGY
·
2023
·Vol. 57
·期 3
·717-739
·
IF 3.4
Li Yanchen,Zhang Weiye,Sun Jingmeng,Fang Xiaoyang,Wang Beibei,Li Fangzhou,Zhang Daihui,Guo Hongwu,Liu Yi
Wood is a great natural material with good energy storage and temperature adjustment for the energy crisis. In this study, wood was delignified, and the PEG-based eutectic polymer (PGMA) was impregnated into the delignified wood, and styrene (SM) grafted AlN was selected as thermal conductive filler to synthesize a stable phase change heat storage wood. The result shows that the styrene (SM) polymerized on the surface of AlN to form polystyrene (PS), and the dispersion of AlN was enhanced. The thermal stability and loss resistance of PCES-Wood are improved for the penetration of PS-AlN into the cavities, which is attributed to the PS-AlN playing a “limiting” role in the crystallization of PGMA. When the content of PS-AlN is 6%, the thermal conductivity of PCES-Wood reaches 0.5148 W/(m·K). 4% PS-AlN-PCES@Balsa has the lowest undercooling and heat loss rate, and the melting enthalpy and solidification enthalpy reach 125.60 J/g and 120.30 J/g, respectively. The phase change temperature range is between 19.59 and 33.87 °C, which is in the comfortable temperature range for humans. Under the illumination of the simulated solar light source, the surface temperature of PS-AlN-PCES@Balsa rises rapidly and shows a lasting heat storage capacity at low temperatures compared with the original wood. After 200 cold and hot cycle tests, the phase change enthalpy of PS-AlN-PCES@Balsa is still high, and there is a slight leakage phenomenon. The phase change wood prepared in this study shows that it is a potential material to store and release solar energy in practical applications.
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JOURNAL OF MOLECULAR LIQUIDS
·
2023
·
IF 6
Fuliu Yang,Jixue Fan,Lingqiang Meng,Jian Wu,Jun Li,Zhuhong Yang,Yifeng Chen,Xiaoyan Ji
Deep eutectic solvents (DESs) are considered as the highly effective absorbents for sulfur dioxide (SO 2 ) capture. However, the high viscosity of DESs and the resulting slow absorption rate as well as low absorption capacity at low SO 2 concentration seriously hinder their industrial application. In this study, DES of N-methyldiethanolamine (MDEA) and imidazole (Im) is simply blended with ethylene glycol (EG) forming a hybrid absorbent, namely MDEA/Im-EG, which exhibits extremely high SO 2 capture capacity at low concentration. In particular, SO 2 capture capacity in MDEA/Im-EG (molar ratio = 1:1) reaches 0.446 g SO 2 /g absorbent at 293.2 K with SO 2 concentration of 2000 ppm. Moreover, the corresponding desorption enthalpy is only −40.67 kJ/mol. To well understand the results, thermodynamic analysis of SO 2 capture is performed and the SO 2 capture mechanism is speculated by nuclear magnetic resonance and Fourier transform infrared spectroscopy.
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高影响因子
CARBON
·
2023
·
IF 10.9
Yushi Yang,Xiaoqiang Fan,Zhaofan Yue,Minhao Zhu
Heterogeneous materials are an ideal platform for low friction, but most of the heterogeneous materials used in tribology field are artificially synthesized. Here, by matching the molybdenum disulfide (MoS 2 ) hybrid polyethylene glycol (PEG 200) and diamond-like carbon (DLC) film, the spontaneous formation of heterogeneous transfer film was realized during sliding. Thus, the anti-friction/wear ability of the synergetic system is improved from the reduction of friction coefficient and wear rate by 33.3% and 32.1% contrast to DLC film, severally. The characterization results show that the heterogeneous transfer film is formed by the rehybridization and recrystallization of MoS 2 and DLC combined with amorphous phase. The improvement on shearing capacity and bearing capacity of as-designed lubrication strategy better explicates the solid-liquid synergistic effect. The formation theory of heterojunction in solid-liquid composite lubrication is put forward, which has important reference value for the future solid-liquid composite lubrication technology.
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高影响因子
Materials Today Chemistry
·
2021
·
IF 8.301
J. Chen,L. Liu,J. Huang,C. Sheng,L. Li
A composite adsorbent, chitosan//poly (ε-caprolactone)-block poly (ethylene glycol)/SiO 2 aerogel@polydopamine (CS/PCL-b-PEG/SA@PDA) membrane was prepared for the adsorption of organic dyes. The matrix polymer materials of this novel adsorbent were eco-friendly. SiO 2 aerogel with nanoporous network construction was fixed in the multicomponent polymer fibers through simultaneous electrospinning-electrospray technology followed by modification of polydopamine (PDA). The composite adsorbent had a maximum adsorption capacity of 598.8 mg/g for Congo red (CR) and possessed good reusability performance. This adsorbent showed excellent performance for the selective adsorption of relatively large molecule CR dyes even under high concentration of small molecule methyl orange (MO) dyes or 1 M of salt solution. The adsorption mechanism indicated that the –NH 2 and –OH groups in adsorbent could generate the stronger electrostatic attraction with the –SO 3 - groups in CR. Meanwhile, the sufficient adsorption spaces of the adsorbent were constructed by the porous network structure of SiO 2 aerogel, the accumulation of PDA particles and the porous structure of the multicomponent composite membrane . The work provided a proactive study in designing an adsorbent for the selective adsorption of organic dyes.
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高影响因子
POLYMER COMPOSITES
·
2023
·
IF 5.2
Yao Peng,Yao Wang,Yingdi Dan,Zengkun Li,Quankai Sun,Yanxin Wang,Wei Wang,Zhonglin Du,Linjun Huang,Matt J. Kipper,Laurence A. Belfiore,Jianguo Tang
In this work, innovative hybrid poly(ethylene terephthalate) (PET) materials with strong luminescence were successfully synthesized by doping PET with silicon-linked poly(ethylene glycol)-PET copolymer nanostructures either with (Si-PEG-PET) or with (ETP@Si-PEG-PET) luminescent Eu 3+ -complexes. The chemical properties and nanostructures of the hybrid materials were characterized by Fourier-transform infrared spectroscopy, nuclear magnetic resonance spectroscopy, x-ray photoelectron spectroscopy, and high-resolution transmission electron microscopy. PET composites ranging from 0.25 to 4 wt% silicon additive were prepared by the melt blending method. The crystal properties, mechanical properties, and fluorescence properties of the composites were systematically studied by differential scanning calorimetry, x-ray diffractometry, tensile testing, and fluorescence spectrometry. When the addition of Si-PEG-PET or ETP@Si-PEG-PET was 0.75 wt%, the relative crystallinity and maximum tensile strength increase substantially. Moreover, the fluorescence intensity of hybrid luminescent PET materials is the strongest at 0.75 wt% loading. ETP@Si-PEG-PET not only endows PET polyester with stronger fluorescence properties and mechanical properties but also acts as an effective nucleation additive for PET. Highlights Silicon-linked poly(ethylene glycol)-poly(ethylene terephthalate) (PEG-PET) nanostructures generate hybrid luminescent PET materials. ETP@Si-PEG-PET improves the crystallization rate and crystallinity of PET. The composite with 0.75% addition showed the best fluorescence performance. Three-dimensional-grid structure of ETP@Si-PEG-PET enhances the mechanical property of PET.
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