SENSORS AND ACTUATORS B-CHEMICAL
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2026
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IF 8.3
Meng Luo,Hongrui Huang,Xiao Liu,Danheng Gao,Qiegen Liu,Jin Li,Lianfu Li,Shichuan Xi,Yu Shi,Yuanyuan Song,Shuxuan Li
Novel integrated optofluidic in-fiber SERS probe based on 4-MBA/Ag NPs for high-stability, label-free detection of PYO. • Ultrafast PYO fingerprint identification within 5 s via a competitive coordination recognition strategy. • Quantitative evaluation of PAHs-triggered bacterial virulence enhancement, providing reliable technical support for marine environmental risk assessment and coastal public health early warning. The activation of virulence in Pseudomonas aeruginosa under environmental stress is of great significance for studying the mechanism of bacterial-environment interaction. Pyocyanin (PYO), a key phenazine virulence factor secreted by P. aeruginosa , serves as a direct indicator of bacterial pathogenicity. Herein, we developed a highly integrated optofluidic in-fiber surface-enhanced Raman scattering (SERS) biosensor for rapid, label-free detection of PYO secretion by Pseudomonas aeruginosa under environmental stress. 4-Mercaptobenzoic acid (4-MBA) serves as a molecular recognition linker anchored onto silver nanoparticle (Ag NPs) surfaces, which can undergo competitive coordination with pyocyanin to suppress non-specific interference from coexisting impurities. The nitrogen atoms on the phenazine ring of PYO form Ag–N coordination bonds along with π–metal coupling interactions with Ag NPs. This competitive substitution displaces the Ag–S bonds between 4-MBA and Ag NPs, leading to a concentration-dependent reduction in the characteristic peak intensity of 4-MBA at 1077 cm⁻¹ . The sensor specifically identifies PYO via its characteristic peak at 1345 cm⁻¹ within 5 s, and exhibits a linear range of 10 −5 M to 10 −14 M. The limit of detection (LOD) was calculated as 1.0 × 10⁻ 14 M. Through the sampling tests, we confirm that 50 μM PAHs stress triggers a 1.5-fold increase in PYO secretion of P. aeruginosa , verifying PAHs-induced bacterial virulence enhancement. Benefiting from the specific competitive recognition between 4-MBA and PYO, the sensor exhibits robust anti-interference performance in complex natural seawater matrices. This work provides a sensitive, rapid, and cost-effective SERS platform for bacterial virulence monitoring, offering valuable insights into pollutant-bacterium interactions and public health early warning. Download: Download high-res image (164KB) Download: Download full-size image
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CHEMICAL ENGINEERING JOURNAL
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2026
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IF 12.5
Weidong Li,Hanwen Ge,Sen Ma,Lei Liu,Lin Luo,Zihao Qin,Aiyong He,Chao Wang,Xianhai Zeng
This study developed a technology for pretreating bamboo biomass using a synergistic system of 4-hydroxybenzoic acid (4-HA) and formic acid (FA). By optimizing reaction temperature, reaction time, and acid concentration parameters, the bamboo hemicellulose removal yield of 99.53% was achieved, whilst glucose and lignin removal yield were only 9.28% and 9.69%, respectively. Characterization results indicated that the surface morphology of the pretreated solid residue exhibited disordered features, with significantly enhanced crystallinity and thermal stability. Subsequent experiments with model lignin compounds confirmed that 4-HA addition effectively inhibited lignin degradation. Nuclear magnetic resonance (NMR) analysis indicated reductions in S and G units alongside an increase in H units. Combining density functional theory (DFT) calculations with molecular dynamics simulations (MDS) elucidated the synergistic mechanism of 4-HA and FA in hemicellulose removal and lignin depolymerization inhibition. Enzymatic hydrolysis achieved separation of the three major components. This strategy offered novel insights for precise hemicellulose removal during biorefinery.
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ACS Applied Energy Materials
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2026
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IF 5.5
Zhenghong Yan,Zhenye Zhu,Gefeng Li,Liang Zhou,Yuhao Wang,Guanghao Mao,Xinyi He,Juntao Lin,Rongshu Zhu
The practical application of conventional nonflammable electrolytes in lithium metal batteries (LMBs) is significantly hampered by their side reactions with lithium metal, which cause unstable solid electrolyte interphases (SEIs) formation and lithium dendrite growth. To address these challenges, a cosolvent, 4-chloroanisole (PCA), is incorporated into the high-flash-point solvent 3-methyl-2-oxazolidinone (MO) to create a localized high concentration electrolyte (LHCE), designated as MO/PCA. This electrolyte exhibits excellent compatibility with both the lithium anode and the LiFePO4 (LFP) cathode. In combination with the bis(trifluoromethanesulfonyl)imide (TFSI–) anion and fluoroethylene carbonate (FEC) additive, the PCA cosolvent promotes the formation of SEIs enriched with inorganic species such as LiF, LiCl, and Li2O. These robust interphases effectively protect the electrodes and suppress parasitic side reactions with the solvents. The stable, inorganic-rich SEI enables the LFP||Li cell to retain 90% of its capacity after 1000 cycles at 1C. Even under challenging conditions, including high-load LFP cathodes and lithium-deficient environments, it retains over 90% capacity after 220 cycles. The successful operation of LFP||Li pouch cells (90% capacity retention over 60 cycles at 0.5C discharge) demonstrates the practical applicability of MO/PCA. Moreover, PCA can function as a cosolvent in flame-retardant electrolyte systems such as N-methylcaprolactam (NM) and N,N-dimethylpropyleneurea (DMPU), demonstrating its versatile utility in various electrolyte formulations.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2026
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IF 8.7
Xiaolu Li,Si Wu,Tao Feng,Tong Wu,Xu Zhu
Gold nanoparticles (AuNPs) exhibit excellent catalytic activity but face significant practical constraints, such as insufficient stability and difficult recovery. This study employed a quercetin-mediated green reduction method with chitosan as a stabilizer to synthesize Chitosan/AuNPs (Chit/AuNPs) capable of maintaining long-term dispersion stability (960 h). It was clearly demonstrated that the chitosan dosage is critical for controlling the size of AuNPs, with 0.8 mL of chitosan yielding smaller AuNPs with an average particle size of about 16.8 nm. Subsequently, Chit/AuNPs were immobilized within a calcium alginate network via electrostatic attraction and Ca 2+ cross-linking, successfully fabricating reusable Chitosan/AuNPs@Calcium Alginate (Chit/AuNPs@CaA) composite microspheres. The catalyst exhibited high activity at room temperature, achieving a 4-NP conversion rate of 97.0% within 25 min with an apparent rate constant (k) of 0.168 min −1 . Notably, after five consecutive uses, the conversion rate remained at 96.9% within 25 min, confirming its reliability as a reusable catalyst. Furthermore, in real water samples, the catalyst maintained over 96.1% conversion rate, demonstrating strong environmental tolerance. This research contributes to the development of novel catalytic materials with high activity, remarkable stability, and practical application potential.
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高影响因子
BIOMACROMOLECULES
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2026
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IF 5.9
JiaJun Bi,TianHao Chen,ZeWei Li,YuPeng Zha,Xiao Zhou,YaHao Dong,ZhanAo Lv
Cellulose is highly valuable due to its ready availability, biodegradability, and easy chemical modification. Recently, studies have focused on the chemical modification of cellulose and utilized it as a support for stabilizing metals. In this study, a Schiff base- and imidazole-functionalized cellulose-supported Pd (Cell-SB-IM-Pd) catalyst was prepared and used for the 4-nitrohpenol reduction as well as the synthesis of biaryls. Compared with the raw Cell-Pd catalyst (70%), Cell-SB-IM-Pd exhibited higher catalytic efficiency (90%) in Suzuki reactions, which was attributed to the introduction of C═N and imidazole, providing charge-transfer interaction between them and Pd. The Cell-SB-IM-Pd also showed good to excellent yields (up to 99%) for various substrates in Suzuki reactions under mild conditions. Likewise, we also demonstrated the stability and efficiency of Cell-SB-IM-Pd in the 4-nitrophenol reduction at room temperature in water, with an apparent rate constant of 9.074 × 10–2 min–1. This work provides more insights into the further utilization of cellulose as a Pd host matrix for converting organic pollutants and promoting sustainable chemical reactions.
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高影响因子
ACS Omega
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2026
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IF 5.2
Huanyu Chen,Yuduo Wan,Wanlu Feng,Changjiang Wang,Yang Wang,Yue Chen,Takron Chantadee,Zibo Li,Li Wang
Nectin-4, a cell adhesion molecule frequently overexpressed in non-small cell lung cancer (NSCLC), has emerged as a promising target for theranostic applications due to its involvement in tumor progression and association with poor prognosis. This study aimed to develop radiolabeled agents based on bicyclic peptides for both imaging and targeted therapy for Nectin-4 positive tumors. We designed and synthesized 68Ga-labeled probes ([68Ga]Ga-3 and [68Ga]Ga-5) for PET imaging and 177Lu-labeled agents ([177Lu]Lu-6) for targeted radionuclide therapy. Radiochemical yields and purity were optimized, and the agents were evaluated for cellular uptake, internalization, and biodistribution in Nectin-4-expressing cell lines (H1975, ABC-1, HEK293nectin4) and xenograft models. Target specificity was confirmed through blocking studies with the Nectin-4 specific inhibitor peptide N188. The 68Ga-labeled probes exhibited high radiochemical yields (78–81%) and purity (>95%), with specific uptake observed in Nectin-4-positive cells (e.g., 69.20 ± 2.31%ID/106 cells for [68Ga]Ga-3 at 120 min) and tumors. Blocking studies resulted in significant reductions in uptake, with 39-fold and 22-fold decreases for [68Ga]Ga-3 and [68Ga]Ga-5, respectively, confirming Nectin-4 specificity. [177Lu]Lu-6 showed superior tumor retention (13% uptake) and internalization (3.5%) compared to [177Lu]Lu-FAP-2286/N188, with sustained tumor growth suppression in xenograft models. PET/SPECT imaging revealed high tumor-to-background ratios and favorable pharmacokinetics, highlighting the potential of these agents for clinical application.
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高影响因子
MICROCHIMICA ACTA
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2026
·Vol. 193
·期 6
·407
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IF 5.4
Fan Lihua,Ou Zongyuan,Li Fan,Shi Yiheng,Wu Di,Wu Yongning,Li Guoliang
Sensitive and reliable quantification of Ochratoxin A (OTA) in food is essential for ensuring food safety and protecting public health. In this study, a dual-mode colorimetric and Surface-Enhanced Raman Spectroscopy (SERS) biosensor was developed by integrating DNAzyme-responsive hydrogel and Au@Pt@4-MBN nanozyme for signal amplification. Upon introduction of OTA, a specific cascade reaction was triggered, activating the generated DNAzymes and leading to the disintegration of the hydrogel network and the subsequent release of encapsulated nanozymes. The extent of hydrogel disintegration exhibited a positive correlation with OTA concentration, enabling straightforward quantitative detection. The biosensor demonstrated excellent sensitivity, with detection limits of 0.0668 ng mL⁻¹ (colorimetric) and 0.0342 ng mL⁻¹(SERS). When applied to spiked corn samples, it achieved high recoveries of 98.70%-100.93% (colorimetric) and 95.6%-104.27% (SERS), confirming its reliability. The method also demonstrated high practical applicability for authentic non-spiked samples, with a positive detection rate of 10% that was consistent with the results of the national standard method. This robust platform offers significant potential for sensitive mycotoxin monitoring in food and environmental safety. Graphical The alternative text for this image may have been generated using AI.
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JOURNAL OF FOOD COMPOSITION AND ANALYSIS
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2025
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IF 4.6
Zhichao Zhang,Xiaoqi Wang,Li Wang,Renan Wu,Yan Jin,Ziyuan Duan
The characteristic ‘mutton flavor’ primarily emanated from subcutaneous adipose tissue and was associated with the levels of three branched-chain fatty acids (BCFAs). This study focused on assessing the quantitative distribution of BCFAs in four sheep breeds from northern China and initially explored the influence of genetic and feeding factors through systematic GC-MS analyses and multidimensional statistics. A total of 164 samples were procured from four breeds of Chinese indigenous sheep, including small-tailed Han sheep (SHS, n = 30; rams 12, ewes 18), Altay sheep (AS, n = 30; rams 15, ewes 15), Short-tailed Steppe sheep (STSS, n = 44; rams 14, ewes 30), and HulunBuir sheep (HBS, n = 60; rams 30, ewes 30), all 8 months old. The results indicated that SHS exhibited the highest levels of BCFAs, followed by AS. No significant difference between STSS and HBS, both with notably lower levels of mutton flavor-related BCFAs. Additionally, rams generally harbored higher levels of BCFAs in comparison to ewes. Collectively, this study provides valuable insights for improving the mutton flavor.
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INORGANIC CHEMISTRY
·
2025
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IF 4.7
Qiulian Luo,Jing Li,Jianwu Wei,Binbin Luo,Liya Zhou,Peican Chen,Jie Tian,Jiahong Pan,Alexei V. Emeline,Qi Pang
Metal halide species with multimeric anionic frameworks exhibit outstanding coordination chiralities and intriguing photophysical properties, making them highly promising for emerging photonic applications. However, their chiroptical activities remain largely unexplored to date. Herein, lead-free chiral hybrid 0D materials composed of edge-sharing [Sb2Cl10]4– dimers were synthesized via a natural cooling crystallization. The 0D chiral crystals R/S-1 [(R/S-MBA)4Sb2Cl10] show broad yellow photoluminescence stemming from self-trapped exciton states with a PL peak at 596 nm. R/S-1 exhibits strong circular dichroism (|gCD| ≈ 7 × 10–3) and efficient circularly polarized luminescence (|glum| ≈ 5 × 10–3). This is attributed to the chiral organic cations inducing inorganic sublattice chirality through asymmetric hydrogen-bonding interactions, while the inorganic lattice components adopt a helical arrangement following a 21 symmetry operation. Density functional theory calculations verify a Rashba-type band splitting for R/S-1, confirming the noncentrosymmetric structural distortion and substantial spin–orbit interaction induced by chiral organic cations. Furthermore, we applied chiral scintillators R/S-1 to achieve X-ray-driven asymmetric photopolymerization using circularly polarized emission. This study offers a pathway for the exploration and development of novel lead-free chiral metal halides.
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Journal of Energy Storage
·
2026
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IF 10.7
Chundong Geng,Xin Gao,Qian Li,Yanqiu Xie,Gang Liu,Haoze Wang,He Bai,Fan Jiang,Hongyan Yue
Although interlayer engineering strategies have demonstrated significant potential in enhancing the electrochemical performance of layered manganese vanadates, the role of intercalated crystal water in regulating charge storage behavior should be clarified. Herein, several manganese vanadates (MnV 2 O 6 ·nH 2 O) with different crystal water contents are fabricated, and the storage behaviors are investigated. When the content of crystal water is limited (n = 2), the interlayer crystal water can act as a “pillar” to enhance ion diffusion kinetics, optimize the interlayer charge distribution, and alleviate structural collapse during charge/discharge cycles. However, excessive water molecules (n = 4) can form metastable coordination configurations and induce localized structural damage during repeated charge/discharge processes. As a result, MnV 2 O 6 ·2H 2 O cathode material exhibits an optimal specific capacity (1318.2 C g −1 at 1 A g −1 ) and cycle stability (84.31% capacity retention after 10,000 cycles) better than that of MnV 2 O 6 (507.9 C g −1 at 1 A g −1 , capacity retention of 61.62%) and MnV 2 O 6 ·4H 2 O (591.3 C g −1 at 1 A g −1 , capacity retention of 67.64%). Furthermore, the hybrid supercapacitor assembled with MnV 2 O 6 ·2H 2 O cathode and activated carbon anode (MnV 2 O 6 ·2H 2 O//AC) demonstrates a superior energy density of 59.12 Wh kg −1 at 690.80 W kg −1 , with 87.03% of the original capacity remaining after 10,000 cycles.
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DIAMOND AND RELATED MATERIALS
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2026
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IF 5.1
Jingwen Zhong,Lini Huo,Haiyi Zhong,Peiyuan Li
The rapid and on-site detection of 4-nitrophenol (4-NP), a refractory and highly toxic environmental pollutant, remains a significant challenge. In this study, iron-doped carbon dots (Fe-CDs) were synthesized via a facile one-pot hydrothermal method using a natural herbal precursor, Citri Reticulatae Pericarpium, as the carbon source. Comprehensive characterization revealed that the Fe-CDs are uniform quasi-spherical nanoparticles with hydrophilic surfaces rich in functional groups such as hydroxyl and carboxyl. This structure endows them with dual functionality: strong intrinsic fluorescence and excellent peroxidase-like activity at neutral pH. Leveraging these properties, we constructed a dual-mode (fluorescence/colorimetric) sensing platform integrated with smartphone-based colorimetric analysis for the rapid, on-site detection of 4-NP. The platform exhibited high sensitivity with a detection limit of 0.17 μM, excellent selectivity against common interferents, and reliable performance in real water samples with satisfactory recovery rates (95.45–107.38 %). Furthermore, the intrinsic Fenton-like activity of the Fe-CDs enabled the oxidative degradation of 4-NP This work presents a sustainable and efficient strategy for environmental monitoring and remediation, highlighting the great potential of herb-derived carbon-based nanozymes in portable sensing applications.
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OPTICAL MATERIALS
·
2020
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IF 2.779
Kai Xu,Qingtang Cui,Degao Zhong,Zhe Yu,Tianhua Wang,Lifeng Cao,Qibo Wang,Xiaolong Yu,Bing Teng
Research progress of an organic second-order nonlinear optical crystal 2-(4-(dimethylamino)styryl)-benzothiazole (DMASBT) was grown with slow cooling method and its performance characterization in different aspects were reported. It was found that the crystals had a high second harmonic generation efficiency of 9.8 times higher than that of KDP crystal. Crystal structure of the crystal was investigated by single crystal XRD . It was found that the crystal lattice is monoclinic . In addition, the crystal growth mechanism and intermolecular interaction were analyzed by chemical etching and Hirshfeld surface . The functional groups of the raw materials were determined by FT-IR, Raman, 1 H NMR and elemental analysis . UV–vis–NIR spectrum, dielectric properties under different frequencies, thermal stability, and photostability of the crystal in powder state were also studied.
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