ACS Applied Materials & Interfaces
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2013
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IF 5.008
Gang Wang,Wangen Zhao,Yong Cui,Qingwen Tian,Shang Gao,Lijian Huang,Daocheng Pan
Homogeneous molecular precursor solutions are excellent choices for obtaining smooth absorber layers, and they offer the potential to significantly lower the manufacturing cost of solar cells. Here, we present a thermally degradable metal butyldithiocarbamate-based solution approach to fabricate Cu2ZnSn(S,Se)4 solar cells. Low-cost Cu2O, ZnO, and SnO were used as the starting materials and were dissolved in the ethanol solution of butyldithiocarbamic acid. By tuning the composition of the Cu2ZnSn(S,Se)4 thin film, a power conversion efficiency of 6.03% on the basis of the active area has been achieved.
研究领域:
材料科学
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光伏技术
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薄膜技术
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可持续能源
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高影响因子
ADSORPTION SCIENCE & TECHNOLOGY
·
2025
·
IF 3.2
Yao JiaCheng,Li Li,Yuan Wenhui
Octafluoropropane (C3F8) is widely used as etching agent in refrigeration, air conditioning and semiconductor industries. However, due to its long lifespan and strong infrared absorbing ability, once C3F8 is emitted, the atmospheric radiation absorbing ability will be permanently altered, which will result in a serious greenhouse effect. Therefore, the efficient removal technology of C3F8 is crucial in protecting the environment and alleviating the greenhouse effect. In this work, a series of X-ETS-4 (X: Mg, Ca, Sr, Ba) molecular sieves were synthesized by solvothermal and ion-exchange method. The morphology and structure of the prepared X-ETS-4 were characterized by FT-IR, XRD, and SEM, etc. The adsorption performance of the X-ETS-4 on C3F8 are determined by fixed-bed adsorption breakthrough experiments and single-component isothermal adsorption experiments. The adsorption mechanism was investigated using different adsorption theoretical models. The results show that Ba-ETS-4 exhibits high adsorption capacity and high adsorption selectivity for C3F8, achieving C3F8 adsorption separation at very low concentration (C3F8/N2 volume ratio = 1:400). The saturated adsorption capacity of Ba-ETS-4 on C3F8 reaches 155.17 mg/g (298 K, 170 kPa), which is 15.49 times more than that of Na-ETS-4. In addition, the ideal adsorption solution theory (IAST) separation selectivity of C3F8/N2 reaches 341–941 in the pressure range of 0–170 kPa.
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RESEARCH ON CHEMICAL INTERMEDIATES
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2026
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IF 3.5
Ren Qiuxuan,Xu Jiaojiao,Liu Yuqi,Ma Aijie,Zhang Gai
The development of ORR catalysts that combine high activity with low cost is essential for advancing the practical implementation of related technologies. In this work, an ORR catalyst Co 2 Pc 2 (EP) 4 /RGO was successfully synthesized via a facile π-π self-assembly approach, where spherical binuclear metallophthalocyanine (Co 2 Pc 2 (EP) 4 ) was loaded onto the surface of reduced graphene oxide (RGO). The structural and morphological characteristics of Co 2 Pc 2 (EP) 4 /RGO were systematically investigated using X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). Electrochemical performance tests showed that the onset potential ( E 0 ) of Co 2 Pc 2 (EP) 4 /RGO was comparable to that of commercial Pt/C, while the half-wave potential (E 1/2 ) of Co 2 Pc 2 (EP) 4 /RGO exhibited a positive shift of 130 mV compared to that of pure Co 2 Pc 2 (EP) 4 . The electrocatalytic activity of Co 2 Pc 2 (EP) 4 / RGO dramatically enhanced because of π-π interactions between Co 2 Pc 2 (EP) 4 and RGO, which promoted the oxygen molecules concentration around the active sites. The high oxygen molecules concentration is conducive to form an intermediate O 2 ads - Co 2 Pc 2 (EP) 4 @RGO to decrease the activation energy of the *OOH dissociation step in a four-electron ORR process and the oxygen molecules could be reduced more easily. This study offers a new direction for the design of oxygen reduction reaction catalysts.
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Sustainability
·
2026
·Vol. 18
·期 16
·8079
·
IF 4.1
Hao Liu,Deli Wu,Yufan Chen,Chengsi Hou,Guojie Ye,Zhengwei Zhou,Yue Wang
4-Chlorophenol (4-CP) is a persistent and highly toxic pollutant commonly found in groundwater. However, its efficient degradation remains challenging due to the rapid agglomeration of conventional zero-valent iron (ZVI) nanoparticles, their narrow pH operating range, and the environmental risks associated with synthetic chelating agents. To address these limitations, this study presents a rationally designed catalytic system integrating cyclodextrin polymer (CDP)-supported bimetallic Cu-Fe nanoparticles (Cu-Fe-CDP) with citric acid (CA) as a green complexing agent. The porous CDP matrix effectively mitigates nanoparticle agglomeration and provides abundant active sites, while the Fe-Cu bimetallic coupling accelerates electron transfer and iron corrosion. Critically, CA acts as a biocompatible ligand that sustains Fe(II)/Fe(III) redox cycling, expands the effective pH range, and enhances hydroxyl radical (·OH) generation. The system achieves 92.13% degradation of 4-CP within 80 min at pH 9.0 and nearly complete removal at pH values between 3.0 and 7.0. Mechanistic studies, including electron paramagnetic resonance (EPR) spectroscopy and radical quenching tests, confirm the dominance of ·OH radicals (82.67% inhibition by TBA) and the essential role of surface Fe(II)/Fe(III) cycling. The catalyst exhibits excellent reusability, broad-spectrum activity toward multiple pollutants, and sustained performance in real water matrices and long-term column tests with minimal metal leaching. This work demonstrates a chemically robust strategy for chlorophenol remediation using green citric acid and biodegradable CDP without exogenous oxidant addition, showing promise for further development toward practical applications.
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Science China-Life Sciences
·
2026
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IF 9.6
Ye Hanyi,Jin Wei,Feng Yifan,Wu Ze,Sun Shuhui,Cui Mengyao,Lv Shun,Jin Bing,Liu Chang,Wang Siming,Li Ying,Dong Zhengqi
Breast cancer remains a therapeutic challenge due to its high malignancy and the lack of safe and effective treatments. Immune checkpoint inhibitors targeting cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) have demonstrated remarkable efficacy against various malignancies by enhancing antitumor immunity when used in combination with chemotherapy. However, conventional antibody-based therapies are associated with adverse effects. Plant-derived microRNAs capable of regulating gene expression represent a highly promising alternative strategy, with substantial potential in disease treatment. In this study, we identified that miR152, a plant-derived microRNA from Taxus×media Rehder, has antitumor activity. Our results demonstrated that miR152 exerts antitumor immune activity by silencing CTLA-4 expression in regulatory T cells. Furthermore, we observed that miR152 maintains a favorable safety profile in normal cells at therapeutic doses, while eliciting direct cytotoxic effects on specific cancer cell lines at higher concentrations. In a mouse tumor model, the combination of anti-CTLA-4 miRNA with doxorubicin significantly improved the efficacy of both monotherapies. Mechanistically, miR152 augmented the antitumor immune response by reducing the proportion of Treg cells within the T-cell compartment and increasing the proportion of CD8 + cytotoxic T cells at tumor sites, enhancing the secretion of Th1- and M1-associated cytokines and suppressing interleukin-10 production. This study reveals for the first time that plant-derived miR152 may serve as a cancer immunotherapy agent in combination with a chemotherapeutic drug to inhibit cancer growth in mammals.
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PubMed
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COLLOIDS AND SURFACES B-BIOINTERFACES
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2026
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IF 5.9
Xueli Hou,Fang Jian,Jinyao Xu,Fanfan Zhang,Shengyue Wu,Dexin Xia,Lin An
A multifunctional pH‑responsive calix[4]arene‑based carrier CMP with dual hydrophobic alkyl substituents and biotin‑PEG chains was constructed for co‑delivery of DOX and Ce6. • The blank calixarene matrix acts as a supramolecular chemotherapeutic agent with certain intrinsic antitumor activity, while co-loaded DOX and Ce6 elicit prominent in vitro chemo-photodynamic suppression. • The biotin‑targeted DOX@CMP@Ce6 nanosystem achieves potent in vivo tumor inhibition along with favorable biosafety. Conventional nanoplatforms often suffer from complicated fabrication, poor structural controllability, insufficient tumor targeting, and unsatisfied therapeutic efficacy. To address these issues, herein we rationally design and construct a novel calix[4]arene derivate CMP, whose upper rim is functionalized with pH-responsive biotin-PEG hydrophilic chains, and lower rim is dually modified with hydrophobic alkyl chains and antitumor pharmacophores. This “all-in-one” supramolecule can not only serve as an excellent supramolecular chemotherapeutic agent itself, but also act as a versatile carrier to co-deliver doxorubicin (DOX) and chlorin e6 (Ce6). The nanoplatform therefore integrates two types of chemotherapeutic modalities and biotin-targeted photodynamic therapy for multi-modal tumor treatment. Notably, in vivo experiments demonstrate that the resultant DOX@CMP@Ce6 nanosystem achieves a 90.5% tumor growth inhibition rate, while displaying biotin-mediated tumor tropism, excellent biocompatibility, and robust triple-modality combinatorial therapeutic effects. Collectively, this work provides key insights into the rational construction of multifunctional supramolecular platforms, reinforcing the broad prospects of calixarene derivatives for nanomedical applications.
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SENSORS AND ACTUATORS B-CHEMICAL
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2026
·
IF 8.3
Meng Luo,Hongrui Huang,Xiao Liu,Danheng Gao,Qiegen Liu,Jin Li,Lianfu Li,Shichuan Xi,Yu Shi,Yuanyuan Song,Shuxuan Li
Novel integrated optofluidic in-fiber SERS probe based on 4-MBA/Ag NPs for high-stability, label-free detection of PYO. • Ultrafast PYO fingerprint identification within 5 s via a competitive coordination recognition strategy. • Quantitative evaluation of PAHs-triggered bacterial virulence enhancement, providing reliable technical support for marine environmental risk assessment and coastal public health early warning. The activation of virulence in Pseudomonas aeruginosa under environmental stress is of great significance for studying the mechanism of bacterial-environment interaction. Pyocyanin (PYO), a key phenazine virulence factor secreted by P. aeruginosa , serves as a direct indicator of bacterial pathogenicity. Herein, we developed a highly integrated optofluidic in-fiber surface-enhanced Raman scattering (SERS) biosensor for rapid, label-free detection of PYO secretion by Pseudomonas aeruginosa under environmental stress. 4-Mercaptobenzoic acid (4-MBA) serves as a molecular recognition linker anchored onto silver nanoparticle (Ag NPs) surfaces, which can undergo competitive coordination with pyocyanin to suppress non-specific interference from coexisting impurities. The nitrogen atoms on the phenazine ring of PYO form Ag–N coordination bonds along with π–metal coupling interactions with Ag NPs. This competitive substitution displaces the Ag–S bonds between 4-MBA and Ag NPs, leading to a concentration-dependent reduction in the characteristic peak intensity of 4-MBA at 1077 cm⁻¹ . The sensor specifically identifies PYO via its characteristic peak at 1345 cm⁻¹ within 5 s, and exhibits a linear range of 10 −5 M to 10 −14 M. The limit of detection (LOD) was calculated as 1.0 × 10⁻ 14 M. Through the sampling tests, we confirm that 50 μM PAHs stress triggers a 1.5-fold increase in PYO secretion of P. aeruginosa , verifying PAHs-induced bacterial virulence enhancement. Benefiting from the specific competitive recognition between 4-MBA and PYO, the sensor exhibits robust anti-interference performance in complex natural seawater matrices. This work provides a sensitive, rapid, and cost-effective SERS platform for bacterial virulence monitoring, offering valuable insights into pollutant-bacterium interactions and public health early warning. Download: Download high-res image (164KB) Download: Download full-size image
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MOLECULES
·
2026
·Vol. 31
·期 17
·3096
·
IF 5.1
Haixia Wu,Dianheng Yu,Jinliang Hu,Fang Wang,Songtao Zhang,Kailu Guo,Huan Pang
Metal–organic frameworks (MOFs) have significant potential in electrochemical sensors, but the guest molecules and residual solvents in the pores often block the active sites and limit the reaction kinetics. One-dimensional nanostructures can provide direct conduction pathways and shorten ion diffusion distances, thereby enhancing electron transport and electrode contact. Meanwhile, fluorine-incorporated MOF materials leverage the high electronegativity of fluorine to substitute oxygen, suppress oxidation to widen the voltage window, and improve stability through enhanced hydrophobicity. In this work, 4-fluorosalicylic acid (4FSA) was used as the ligand and benzimidazole (Bim) was introduced to adjust the coordination environment, and one-dimensional Bim4FSA-MOF nanorods were successfully constructed. While the guest molecules were largely removed, the nickel sites were thereby activated and the pore size was enlarged. Due to the synergistic effect of one-dimensional nanostructure-promoted electron transport and the Ni(OH)2/NiOOH dynamic active center, the B-250 composite exhibited excellent performance in a glucose electrochemical sensor. The optimized sensor delivered a detection limit of 0.022 μM and a detection time of 0.9 s, along with a sensitivity value of 2986.45 μA mM−1cm−2, which provides a new strategy for the design of efficient MOF-based electrochemical sensor interface.
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Solar RRL
·
2026
·Vol. 10
·期 9
·e70362
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IF 4.8
Yingjun Zhou,Chuanhe Ma,Shulei Liang,Yujun Li,Hailong Wang
In Cu 2 ZnSn(S, Se) 4 (CZTSSe) solar cells, the conventional magnetron-sputtered ZnO (ZnO-SP) suffers from high cost, low efficiency, and interface damage. This study systematically compares sol–gel ZnO (ZnO-SG) and 18C6 crown ether-modified sol–gel ZnO (ZnO-SG-18C6) as interfacial layers. X-ray diffraction (XRD), scanning electron microscope (SEM), AFM, and X-ray photoelectron spectroscopy (XPS) show ZnO-SP has a uniform hexagonal wurtzite structure, whereas ZnO-SG displays an amorphous fibrous morphology with bright/dark striations. Both exhibit similar UV absorption peaks, but ZnO-SG shows broader absorption and double-exponential decay. Density–voltage ( J – V ) tests reveal that ZnO-SG-18C6 increases PCE from 8.5% to 10.6%, surpassing the 9.5% achieved with ZnO-SP. Electrochemical impedance spectroscopy (EIS) analysis shows that the ZnO-SG-18C6 layer reduces carrier recombination, with the charge transfer resistance ( R ct ) increasing by 30%. Transient photocurrent measurements further reveal that it enhances the photocurrent response, achieving a 1.8-fold increase in the peak, which rises to four times under a 70% high duty cycle.This work demonstrates ZnO-SG-18C6 as a low-cost, high-efficiency alternative to ZnO-SP in CZTSSe solar cells.
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ACS Applied Nano Materials
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2026
·
IF 5.8
Guanglin He,Jing Guo
We report a plasmon-mediated route to drive the azo coupling of 4-aminothiophenol to 4,4′-dimercaptoazobenzene on a gold nanostructure on a nanoelectrode (NSoNE) platform. Gold nanostructures were grown on electrochemically etched gold nanoelectrodes to form NSoNE substrates. The curved tip showed a larger enhancement factor than the planar rear surface, with values of 1.31× 104 and 3.08 × 103. Surface-enhanced Raman spectra tracked the azo coupling reaction in real time. At 88 μW μm–2, the curved tip reached a steady state in 37.5 s, while the planar region required 108.4 s. Reducing the power to 44 μW μm–2 slowed the process. Phenyl isocyanide (PIC) served as a molecular thermometer. The C≡N peak of PIC showed a linear red shift with temperature, with a slope of −0.246 cm–1 °C–1. Calibrated maps revealed a nonuniform thermal field that peaked at the tip. Potassium bromate was used to consume hot electrons. The reaction still proceeded in 0.8 mmol L–1 of KBrO3 but with longer steady-state times of 56.4 s at the curved tip and 109.3 s at the planar region. Dark-field heating experiments indicate that thermal effects can effectively activate the 4-ATP coupling reaction, yet they are insufficient to achieve the maximum reaction state. Overall, the results demonstrate that thermal effects can activate and accelerate the reaction process, with the most pronounced influence near the tip; moreover, electron-related reaction pathways also play a certain role.
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ACS Omega
·
2026
·
IF 5.2
Huanyu Chen,Yuduo Wan,Wanlu Feng,Changjiang Wang,Yang Wang,Yue Chen,Takron Chantadee,Zibo Li,Li Wang
Nectin-4, a cell adhesion molecule frequently overexpressed in non-small cell lung cancer (NSCLC), has emerged as a promising target for theranostic applications due to its involvement in tumor progression and association with poor prognosis. This study aimed to develop radiolabeled agents based on bicyclic peptides for both imaging and targeted therapy for Nectin-4 positive tumors. We designed and synthesized 68Ga-labeled probes ([68Ga]Ga-3 and [68Ga]Ga-5) for PET imaging and 177Lu-labeled agents ([177Lu]Lu-6) for targeted radionuclide therapy. Radiochemical yields and purity were optimized, and the agents were evaluated for cellular uptake, internalization, and biodistribution in Nectin-4-expressing cell lines (H1975, ABC-1, HEK293nectin4) and xenograft models. Target specificity was confirmed through blocking studies with the Nectin-4 specific inhibitor peptide N188. The 68Ga-labeled probes exhibited high radiochemical yields (78–81%) and purity (>95%), with specific uptake observed in Nectin-4-positive cells (e.g., 69.20 ± 2.31%ID/106 cells for [68Ga]Ga-3 at 120 min) and tumors. Blocking studies resulted in significant reductions in uptake, with 39-fold and 22-fold decreases for [68Ga]Ga-3 and [68Ga]Ga-5, respectively, confirming Nectin-4 specificity. [177Lu]Lu-6 showed superior tumor retention (13% uptake) and internalization (3.5%) compared to [177Lu]Lu-FAP-2286/N188, with sustained tumor growth suppression in xenograft models. PET/SPECT imaging revealed high tumor-to-background ratios and favorable pharmacokinetics, highlighting the potential of these agents for clinical application.
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Journal of Environmental Chemical Engineering
·
2026
·
IF 7.5
Jin-Xing Zheng,Min-Hua Cui,Yan Zhang,Jing Wu,He Liu,Zhi-Yong Zheng
Nitrophenols are toxic and recalcitrant organic pollutants, posing a major challenge for wastewater treatment. Herein, a Fe-doped cyanobacterial biochar catalyst (Fe 3 /C 1 -800) was fabricated via a one-step impregnation pyrolysis strategy using lake-harvested cyanobacterial biomass as the carbon matrix and FeCl 3 ∙6H 2 O as both the in-situ activator and Fe source realizing the 'waste-to-treat-waste' concept. When applied to the catalytic reduction of 4-nitrophenol (4-NP), the Fe 3 /C 1 -800/NaBH 4 system achieved nearly complete reduction of 4-NP within 5 min, with a high turnover frequency (TOF) of 0.67 mmol·g -1 ·min -1 , surpassing most reported transition-metal catalysts and approaching noble-metal activity. The catalyst exhibited high efficiency over a wide pH range (3-11) and temperature range (15-45 ℃), resisted interference from Cl - and NO 3 - , and retain 93.7% of its activity after four consecutive cycles. In real water matrices (Lake Taihu water and secondary effluent from a sewage treatment plant), the 4-NP removal efficiency reached 95.4% and 88.1%, respectively. Mechanistic investigations revealed a synergistic effect between the catalyst’s large specific surface area (802.16 m 2 ·g -1 ) for 4-NP adsorption and the Fe 2+ /Fe 3+ redox cycle for accelerated electron transfer. This synergy promotes BH₄⁻ dissociation to generate active hydrogen species, enabling the selective reduction of 4-NP to 4-aminophenol (4-AP) with 97% selectivity. Furthermore, Fe 3 /C 1 -800 displayed broad-spectrum catalytic activity toward diverse nitrophenol contaminants (e.g., o -nitrophenol, p -nitrotoluene) with conversion rates >90%. This work not only offers a low-cost, eco-friendly pathway for cyanobacterial valorization but also offers a novel design principle of high-performance biochar-based catalysts, advancing the development of sustainable reduction systems for refractory organic wastewater.
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