PHYSICAL CHEMISTRY CHEMICAL PHYSICS
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2024
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IF 2.9
Jianzhi Wang,Jie Yang,Fuhua Huang,Yuru Li,Yu Luo,Yanan Xue,Ning Cai,Hui Li,Faquan Yu
The design of efficient, stable and cost-effective electrocatalysts for hydrogen evolution reaction holds substantial significance in water electrolysis, but it remains challenging. Tremella-like nickel-molybdenum bimetal phosphide encapsulated cobalt phosphide (NiMoP/CoP) with hierarchical architectures have been effectively synthesized on nickel foam (NF) via a straightforward hydrothermal followed by a low-temperature phosphating method. Based on the unique structural benefits, it significantly increases the number of redox active centers, enhances the electrical conductivity of materials, diminishes ion diffusion path lengths, thereby promoting the efficient electrolyte penetration and reducing the inherent resistance. The as-obtained NiMoP/CoP/NF electrocatalyst exhibited remarkable catalytic activity with a ultralow overpotential of 38 mV (10 mA cm-2) and low Tafel of slope (83 mV dec-1). The straightforward synthesis process and exceptional electrocatalytic properties of NiMoP/CoP/NF demonstrate great potential for HER to replace the precious metal catalyst.
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ADVANCED FUNCTIONAL MATERIALS
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2024
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IF 18.5
Jiafei Hu,Yan Liu,Chengxiu Yang,Shaowei Wu,Haomiao Wang,Yuhang Qin,Yuchen Yong,Lihui Liu,Xu Li,Shijie Gu,Yueguo Hu,Peisen Li,Jian Huang,Qi Zhang,Mengchun Pan
Long-term access to undersea information is of critical importance for undersea sensing. However, the paramount challenge in marine wearable technology lies in achieving durable and stable adhesion, coupled with biocompatibility, for devices submerged in the saline conditions of the ocean. Here, a self-healing, seawater-resistant hydrogel is reported that exhibits robust adhesion to diverse biotic and abiotic surfaces. Remarkably, the presented hydrogel is augmented with octopus sucker-inspired microstructures, a feature that markedly improves its capability of organism adhesion underwater. The hydrogel exhibits robust mechanical properties in water, with over 20-fold elongation in a fully swollen state, and a mechanical healing efficiency exceeding 90% after healing for 30 min. The hydrogel is applied toward several representative undersea scenes. Specifically, the hydrogels equipped with flexible pressure sensors are reliably affixed to fish and turtles for sensing hydraulic pressure for more than 20 days, while the hydrogels featuring a compact camera are mounted on corals and crabs for constant monitoring of surroundings. Furthermore, the hydrogel is molded into a mesh structure for integrating multiple sensors, functioning as multi-node marine wearable platforms. The underwater hydrogel, with its broad applicability, introduces an approach to real-time undersea monitoring and non-invasive marine life internet construction.
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MICROCHIMICA ACTA
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2025
·Vol. 192
·期 2
·1-9
·
IF 5.3
Xie Hui,Xie Sihui,Jiang Li,Lei Chenghong
Ce-MOFs with ferrocenedicarboxylic acid ligands (Ce-FcDC) as a bifunctional nanozyme exhibited high peroxidase (POD)-mimicking activity and superoxide dismutase (SOD)-mimicking activity. H 2 O 2 was produced from catalytic hydrolysis of peroxymonosulfate (PMS) using Ce-FcDC as a catalyst. The growth of E. coli and S. aureus were synergistically and more effectively suppressed by PMS in the presence of Ce-FcDC, in comparison with the sole use of PMS or Ce-FcDc. Under the catalysis of Ce-FcDC as the POD-mimicking nanozyme, PMS could be activated by Ce-FcDC to produce SO 4 •− and •OH and H 2 O 2 from the hydrolysis of PMS was further derivatized to O 2 •− and •OH. Ce-FcDC as the SOD-mimicking nanozyme causes O 2 •− to form H 2 O 2 . The generation of O 2 •− and •OH were confirmed using p-benzoquinone and isopropanol alcohol as the scavengers. The resulted SO 4 •− , O 2 •− , and •OH from combination of PMS with Ce-FcDC as an activator may have key roles for suppressing the growth of E. coli and S. aureus . This strategy could be an effective approach for suppressing the growth and preventing infections or pollutions of some other microbial cells as well. Graphical abstract
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JOURNAL OF PHYSICAL CHEMISTRY B
·
2025
·
IF 2.9
Haiyang Huang,Yong Zhou,Ling Xie,Bing Li,Wenlong Wang,Xinjuan Liu,Yongli Huang,Chang Q. Sun,Biao Wang
Hydrogels are versatile functional materials with applications in biomedical devices, sensors, and energy systems. However, tailoring their mechanical properties remains a critical challenge for expanding their practical utility. Here, the mechanical properties of poly(vinyl alcohol) (PVA) hydrogels prepared via the freeze–thaw method were effectively tailored through the incorporation of various chloride salts. This study reveals the molecular mechanisms by which salt ions influence the water structure, polymer chain interactions, and freezing behavior to modulate hydrogel performance. Using Raman spectroscopy, X-ray diffraction (XRD), and Fourier-transform infrared spectroscopy (FTIR), we elucidate how cation-specific effects alter the crystallinity, cross-linking density, and hydrogen bond network in the hydrogels. Hydrogels containing K+ exhibited superior rigidity and toughness due to enhanced crystallinity and optimized water–polymer interactions, while hydrogels of Mg2+ and Ca2+ had much lower modulus and adhesion strength since the divalent ions reduced freezing points resulting in reduced polymer aggregation. These findings provide a molecular-level understanding of the salting effects on hydrogel properties, offering new insights into designing materials with tunable mechanical performance for diverse applications.
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MICROCHEMICAL JOURNAL
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2025
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IF 5.1
Xinyi Zhou,Siyu Fang,Luoyan Lin,Hao Feng,Tianyu Li,Lu Fang
Heparin is vital in treating thrombotic disorders; it works well as an anticoagulant coating on biomedical devices. Due to its pharmacological nature, excessive heparin can lead to thrombocytopenia, hemorrhage, and hyperkalemia, while too little may cause thrombi. Precise measurement of heparin concentration is essential for clinical practice; therefore, this study developed a heparin sensor utilizing Poly(3,4-ethylenedioxythiophene): Poly(styrenesulfonate) PEDOT:PSS/gold nanoparticle (AuNPs) nanocomposites. Heparin quantification is achieved via the specific protamine-heparin interaction, with protamine immobilized on the electrode surface. We systematically optimized the deposition conditions of PEDOT:PSS/AuNPs and the concentration of protamine and its incubation time. Following this optimization, the sensor's performance was evaluated using cyclic voltammetry (CV) in a 0.5 mM [Fe(CN)₆] 3−/4- solution over a voltage range spanning from −0.3 V to 0.7 V. The GCE/PEDOT:PSS/AuNPs/PRTM sensor achieved a heparin sensitivity of 8.113 μA·mM −1 ·cm −2 , a low detection limit of 0.05 μM, and a wide linear detection range of 0-35 μM. Under simulated physiological conditions (2.5 % human serum - containing buffer), the system exhibited a linear response to heparin (0–35 μM) and achieved recovery rates of 95.2 %–101.5 %, confirming its anti-interference capability in biological environments. The sensor demonstrated rapid response, high selectivity, wide linear range, and robust reliability, thus enabling its potential as a POCT device for real-time heparin monitoring in blood.
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JOURNAL OF ELECTROANALYTICAL CHEMISTRY
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2025
·
IF 4.1
Zhishan Liang,Yingming Ma,Ying He,Mengjiao Dai,Dongxue Han
Abnormal dopamine (DA) levels are implicated in numerous physiological disorders—including Parkinson's and Alzheimer's diseases—necessitating highly sensitive and selective analytical methods. Here we report a bismuth tungstate nanoparticle-modified glassy‑carbon electrode (Bi 2 WO 6 NPs/GCE) that enables chronoamperometric DA sensing with excellent electrocatalytic activity. Operating at an oxidation potential of +0.46 V, the sensor responds linearly to DA from 5 nM to 345 μM (R 2 = 0.9997) and offers a detection limit of 2.7 nM. To further miniaturise the platform, Bi 2 WO 6 NPs were drip-coated onto a laser-induced graphene pattern on eco-friendly polyvinyl chloride laser-induced graphene (PVC-LIG), producing a Bi 2 WO 6 NPs/Chip that functions inside a home-built integrated device. The chip requires only 70 μL electrolyte, operates at a lower potential (+0.22 V), and detects DA from 0.5 to 100 μM with a 14 nM detection limit. Both configurations exhibit excellent reproducibility (RSD < 1 %) and have been successfully applied to spike-and-recovery assays in human serum, demonstrating their promise for point-of-care DA monitoring.
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VETERINARY MICROBIOLOGY
·
2025
·
IF 2.7
Qing Yang,Shengda Xie,Yundi Zhao,Xinxin Lin,Ning Wei,Miaolei Shi,Ruibing Cao
Japanese encephalitis virus (JEV) is a zoonotic pathogen that can be transmitted to humans and animals via arthropods, causing viral encephalitis. In this study, we investigated the role of transferrin receptor 1 (TfR1) in JEV infection. We found that knocking down TfR1 expression in A549 and HeLa cells significantly inhibited JEV entry, while overexpression of TfR1 in 293 T cells enhanced viral entry. The JEV E protein interacts with TfR1, specifically via the protease-like domain (residues 384–606). Additionally, the hTfR1 soluble ectodomain protein significantly blocked JEV infection in HeLa cells, and ferric ammonium citrate (FAC), an iron supplement, downregulated TfR1 expression and effectively inhibited JEV entry and infection. These findings identify TfR1 as an entry factor for JEV and a potential antiviral target, suggesting that small molecule inhibitors like FAC could offer a promising antiviral strategy.
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Materials
·
2025
·Vol. 18
·期 21
·5040
·
IF 3.2
Xueyan Li,Xiaojiang Chen,Senlong Zhang,Jinrong Wang,Zhuo Chen,Yuexian Song
HighlightsWhat are the main findings?Different water-soluble polymers can be used as electrolyte additives.PAA exhibits stable cycling for more than 360 h at 5 mA cm−2, 2 mA h cm−2.What are the implications of the main findings?PAA exhibits an optimum performance.PAA additive can inhibit hydrogen evolution, dendrite growth, and corrosion on the zinc anode.Water-induced corrosion and zinc dendrite formation seriously disrupt the Zn plating/stripping process at the anode/electrolyte interface, which results in the instability of the Zn metal anode in aqueous zinc-ion batteries. To address the issues of the zinc metal anode, three water-soluble polymers with different hydrophilic groups—polyacrylic acid (PAA), polyacrylamide (PAM), and polyethylene glycol (PEG)—were designed as electrolyte additives in ZnSO4electrolytes. Among them, the PAA-based system exhibited an optimal electrochemical performance, achieving a stable cycling for more than 360 h at a current density of 5 mA cm−2with an areal capacity of 2 mA h cm−2. This improvement could be attributed to its carboxyl groups, which effectively suppresses zinc dendrite growth, electrode corrosion, and side reactions, thereby enhancing the cycling performance of zinc-ion batteries. This work provides a reference for the optimization of zinc anodes in aqueous zinc-ion batteries.
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TETRAHEDRON
·
2025
·
IF 2.2
Wenhao Su,Zhouyu Jiang,Zihui Jing,Yandong Xu,Mingzhu Yang,Xiaowen Zhang,Chuyao Wu,Mingliang Wang
Unsymmetrical indocyanine dyes have extremely important applications in the field of biological detection. To address the key challenges of low yield and purity during the synthesis of these compounds, a new method via a two-step process is proposed for the synthesis of a series of the unsymmetrical indocyanine dyes. In the first step, an indole with a quaternary ammonium structure is reacted with a condensing agent in acetic anhydride to synthesize the hemicyanine intermediate. In the second step, an indole with an enamine structure is reacted with the hemicyanine intermediate to synthesize the unsymmetrical indocyanine dye with no additional base catalyst. This effectively inhibits the reverse reaction of the hemicyanine intermediates to indole with a quaternary ammonium structure in basic conditions, thereby suppressing the formation of indocyanine byproducts that are difficult to separate. As a result, the yields of the unsymmetrical indocyanine dyes have been greatly improved. The higher nucleophilicity of indole containing an enamine structure than indole with a quaternary ammonium structure has been reasonable explained by DFT calculations of Frontier Molecular Orbitals and electrostatic surface potentials. This study provided a new strategy for synthesizing high-yield unsymmetrical indocyanine dyes.
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ACS Materials Letters
·
2025
·
IF 8.7
Changjiang Bao,Zhe Zhang,Kun Zhang,Ziqi Guan,Haoyu Wang,Yanxu Wang,Bo Yang,Liang Zuo,Bing Li
The past decade has witnessed remarkable progress in barocaloric refrigeration, but it remains challenging to find a suitable working material with sufficiently large entropy changes under the lowest possible driving pressures. In this study, we report a colossal barocaloric effect in an organometallic sandwich compound, formylferrocene [Fe(C5H5)(C5H4CHO)]. It undergoes a first-order phase transition from orthorhombic to face-centered cubic structure around room temperature, characteristic of a large, pressure-induced entropy change (191 J·kg–1·K–1), an ultralow saturation pressure (20 MPa), and a high pressure sensitivity of its transition temperature (0.27 K·MPa–1). Notably, the pressure-normalized entropy change reaches a record-high value of 9.55 J·kg–1·K–1·MPa–1, surpassing those of all previously reported barocaloric materials. This work highlights the exceptional barocaloric performance of formylferrocene and the potential of organometallic sandwich compounds for emerging barocaloric refrigeration.
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Nature Communications
·
2025
·Vol. 16
·期 1
·1-8
·
IF 15.7
Li Jidong,Zhao Wei,Fu Chenwei,Zhai Zhenpeng,Xu Pengfei,Diao Xinyuan,Guo Wanlin,Yin Jun
Biological nervous systems rely on distinct spiking frequencies across a wide range for perceiving, transmitting, processing, and executing information. Replicating this frequency range in an artificial neuron would facilitate the emulation of biosignal diversity but it remains challenging. Here, we develop an ion-electronic hybrid artificial neuron by compactly integrating a nonlinear electrochemical element with a solid-state memristor. This hybrid neuron employing a minimalist architecture exhibits a tunable spiking frequency spanning five orders of magnitude, significantly surpassing the capability of artificial neurons based on electronic devices. Notably, stimuli-dependent ion fluxes enable inherent afferent sensing of liquid flow, temperature, and chemical constituents, eliminating the need for separate, bulky sensors. Connection to biomotor nerves facilitates muscle actuation with frequency-regulated modes. The frequency encoding of a hybrid neuron array allows for the recognition of handwritten patterns. This hybrid neuron design, taking advantage of both ionic and electronic features, offers a promising approach for advanced e-skin and neurointerface technologies.
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BIOMATERIALS
·
2018
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IF 8.806
Tao Sun,Guangping Zhang,Qingbing Wang,Qinjun Chen,Xinli Chen,Yifei Lu,Lisha Liu,Yu Zhang,Xi He,Chunhui Ruan,Yujie Zhang,Qin Guo,Chen Jiang
Real-time monitoring drug-release is often regarded crucial in theranostics nanomedicine design, since it provides precise establishment of spatio-temporal activation of the drug-release in vitro and in vivo . A symmetrical self-immolative drug-dye conjugation (DDC) prodrug is developed in this study with disulfide bond as the trigger. The prodrug can be escorted by targeting PEG-PLGA micelles and hereby accumulated in the tumor by both active and passive targeting effect. Glutathione (GSH) with higher concentration in the tumor microenvironment can readily cleave the disulfide bond to initiate a subsequent decomposition of DDC, where the drug and dye can be released simultaneously in a strict one-to-one mode. Upon the disintegration, the “Turned-On” probe can emit near-infrared (NIR) fluorescence, with the aim of providing accurate and real-time information for the prodrugs' activation and biodistribution in vivo in a non-invasive way. Furthermore, the released dye can meanwhile act as a photothermic sensitizer, which can in-situ assist a deep penetration for the released drug in the tumor tissue with enhanced therapeutic efficiency. This “babysitting” strategy provides new reference for designing versatile theranostic nanomedicines for preclinical evaluations and an alternative approach for hyperthermia perfusion in clinic.
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