ChemCatChem
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2024
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IF 3.8
Libin Liu,Yuxi Si,Wenjie Zhao,Qingqin Zhu,Zhaoran Yang,Jing He,Yangqiang Huang,Youwei Cheng
Cyclopentanone (CPO) and cyclopentanol (CPL), derived from renewable biomass resource hemicellulose, are considered sustainable chemicals that can substitute fossil-based products, which could be obtained through the hydrogenation-rearrangement reaction of furfural (FFA). However, the inevitable condensation reactions of FFA and furfuryl alcohol (FA) in aqueous solutions generate humins and result in carbon loss, limiting the industrial application of this process. Herein, a series of Cu-based catalysts were synthesized using the reverse co-precipitation method with various metal promoters and applied in the FFA hydrogenation-rearrangement reaction. The highest yield of 97.1% CPO/CPL achieved in a typical reaction condition at 200 °C, 4 MPa, in 20 wt% isopropanol-water mixed solvent over CuZnZr catalyst and the recyclability test confirmed that the catalyst had excellent stability. Experimental studies and characterizations showed that the enhanced performance could be attributed to the adequate Lewis acid sites, regulated through the synergistic interaction between Cu, Zn, and Zr compounds. The simultaneous introduction of Zn and Zr promotes the Cu reduction, and results in more dispersed Cu0 and Cu+, providing an ample and reliable active site. This study outlines a viable method for the catalyst designing and valorizing biomass into high-value-added products.
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Nature Communications
·
2025
·Vol. 16
·期 1
·1-18
·
IF 15.7
Shen Yan,Fang Nan,Liu Xinru,Ling Yu,Su Yuming,Tan Tian,Chen Feng,Lin He,Zhao Boxuan,Wang Jin,Si Duanhui,Xie Shunji,Wang Ye,Zhou Da,Zhang Teng,Cao Rong,Wang Cheng
Interphases are critical in electrochemical systems, influencing performance by controlling ion transport and stability. This study explores a metal-organic interphase in the electrocatalytic reduction of CO 2 (CO 2 RR) on Cu, extending the concept of interphases to CO 2 conversion. Investigating organic modifications on CuO x , we discover metal-organic interphases over 10 nm thick in highly ethanol-selective systems, contrary to the expected monolayer adsorption. Using an automated platform, 1080 CO 2 RR experiments with 180 molecular modifiers identify functional groups affecting selectivity for ethanol and multi-carbon (C 2+ ) products. We find that these modifiers consistently produce metal-organic interphases on the Cu or CuO x surface. These interphases modulate Cu coordination, CO 2 RR intermediates, and interfacial water configuration, significantly improving electrocatalytic performance. Testing across 11 CuO x -based catalysts validates this approach, culminating in the development of two electrocatalysts that achieve ~80% faradaic efficiency for C 2+ products with ethanol partial current densities up to 328 and 507 mA cm −2 . This study highlights the pivotal role of interphases in CO 2 RR, advancing CO 2 conversion technologies.
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Environmental Science-Processes & Impacts
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2024
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IF 4.3
Chang Xu,Bo Gong,Shan Zhao,Xiao-Min Sun,Shu-Guang Wang,Chao Song
Tetracycline (TC) and Cu(II) coexist commonly in various waters, which may infiltrate into the subterranean environment through runoff and leaching, resulting in substantial ecological risks. However, the underlying mechanisms why Cu(II) affects the transport of TC in porous media remain to be further explored and supported by more evidence, especially the role of complexation. In this study, the transport of TC with coexisting Cu(II) was comprehensively explored with column experiments and density functional theory (DFT) calculation. At natural environmental concentrations, Cu(II) significantly inhibited the transport of TC in the quartz sand column. Cu(II) augmented the retention of TC in the column mainly via electrostatic force and complexation. The interaction between TC and TC–Cu complexes on the surface of SiO2 was investigated with first-principles calculations for the first time. There were strong van der Waals forces and coordination bonds on the surface of complexes and SiO2, leading to higher adsorption energy than that of TC and inhibiting its penetration. This study offers novel insights and theoretical framework for the transport of antibiotics in the presence of metal ions to better understand the fate of antibiotics in nature.
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Journal of Building Engineering
·
2024
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IF 6.7
Tianxiao Li,Huabing Zhang,Xiang Tan,Rui Zhang,Fasi Wu,Qinglin Ma,Bingjian Zhang,Bomin Su
Nanomaterials, such as TiO 2 , ZnO, and Cu, have become popular materials for controlling the growth of microorganisms that cause the deterioration of stone monuments, but it is not clear which material is best. In this study, the dominant strains from two stone monuments, the Klippe Statue and Lingyan Temple, were used to compare the antimicrobial activities of the three materials. The minimum inhibitory concentrations (MICs) of the three materials were obtained using the microdilution and macrodilution methods, a linear regression model of the relationship between the addition of the nanomaterial and the color change of the stone was constructed, and the antimicrobial effect of the screened nanomaterial applied to the stone samples was also evaluated. Among the three materials, only the Cu nanoparticles exhibited a broad antimicrobial activity, and its MIC was 0.5 %. There was a linear relationship between the addition of Cu nanoparticles and the color change of the stone, the maximum addition without significant effect on the aesthetic appearance was 67 μg/cm 2 , and there was no difference between the limestone and sandstone. However, the antimicrobial activity of the Cu nanoparticles was only observed in limestone due to the low concentration of the material that could be retained on the sandstone surface. In addition, the adsorption between the Cu nanoparticles and limestone was weak and easily removed by various factors, indicating that the microorganisms could re-colonize the Cu-treated limestone after the limestone was exposed to environmental influences such as rainfall. In this paper, we propose a candidate biocide, Cu nanoparticles, to inhibit the growth of microorganisms on stone monuments, the Klippe Statue and Lingyan Temple, and our results provide a reference for the application of nanomaterials in stone monuments.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2024
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IF 4.3
Wenhui Ai,Ge Chen,Jiayao Chen,Yao Jin,Xiufeng Wang,Ting Zhou,Zhiqing Zhang,Fang Wang,Guodong Zhang
The abuse of antibiotics has seriously threatened human health and living environment. Nevertheless, the detection of quinolones is currently mainly performed by high-cost and cumbersome means, such as High-Performance Liquid Chromatography (HPLC). Herein, we reported a novel method based on copper-doped MoO x nanoparticles (Cu-MoO x NPs) with peroxidase-like enhancement activity for the easy preparation, sensitive and rapid visualization of quinolone detection. Cu-MoO x NPs can make the chromogenic substrate 3,3′,5,5′-Tetramethylbenzidine (TMB) change from colorless to blue. Moreover, the addition of quantitative quinolone antibiotics can significantly accelerate the TMB oxidation reaction. Based on this phenomenon, a colorimetric method for detecting quinolone antibiotics was established with a good linear relationship ranging from 1 × 10 −6 M to 1.3 × 10 −4 M, and the detection limit was 0.310 μM for ciprofloxacin (CIP) and 0.520 μM for levofloxacin (LVFX). Furthermore, the mechanism was also explored, and the results showed that the peroxidase-like activity of Cu-MoO x NPs was probably derived from the generated OH, 1 O 2 , oxygen vacancies and partially reduced Cu + , and on the other hand was derived from quinolone antibiotics and nanozymes electrostatic interaction between them.
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Small
·
2025
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IF 12.1
Huihui Chen,Xiao Hu,Bingying Hou,Liying Qin,Eve-Graciella M.E.K. Kuete,Levinus Hendrik Koole
Bacterial keratitis (BK) is a critical and sight-threatening corneal infection that significantly impairs the quality of life. Due to the widespread antibiotic-resistant microbes and the slow development in antibiotics, there is an increasingly growing demand to create new antimicrobial agents for the treatment of BK. Herein, copper-intercalated molybdenum disulfide (Cu-MoS 2 ) nanosheets are constructed by intercalating Cu into the interlayer structure of MoS 2 via intercalation chemistry, which not only introduces the Fenton reaction but also modulates the electronic structure of MoS 2 . Cu-MoS 2 can convert H 2 O 2 into more toxic reactive oxygen species (ROS), thereby exhibiting excellent bactericidal performance against Staphylococcus aureus (S. aureus) , methicillin-resistant Staphylococcus aureus (MRSA) and Escherichia coli (E. coli) at room temperature in the dark. Animal experiments indicated that Cu-MoS 2 can effectively treat BK caused by MRSA. This work demonstrates that intercalation chemistry as a novel and effective strategy to tune MoS 2 as the antibacterial agent with no reliance on light that has great potential therapeutic effects on clinical drug-resistant BK.
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Foods
·
2024
·Vol. 13
·期 24
·4127
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IF 4.7
Jianguo Huang,Rashid Khan,Chunhui Zhai,Xianting Ding,Li-Sha Zhang,Jin-Ming Wu,Zhizhen Ye
Developing and implementing technologies that can significantly reduce food loss during storage and transport are of paramount importance. Ozone synergistic catalytic oxidation (OSCO) technology has been developed, which sterilizes bacteria and viruses on the surface of food and degrades ethylene released during fruit storage through the active oxygen produced by the catalytic decomposition of ozone. Herein, we report the hydrothermal synthesis of MnO2with distinct phase compositions and nanostructures through simply varying the reaction temperatures. Optimized copper-doped α-MnO2nanorods exhibited remarkable efficacy in activating ozone at a concentration of 40 ppb, and this activation resulted in the complete eradication of indicator bacteria on food surfaces within a 24 h period. Moreover, these nanorods demonstrated high effectiveness in decomposing more than 80% of the ethylene molecules emitted by apples and bananas during the preservation period. The high concentration of surface oxygen vacancies is believed to contribute to the enhanced catalytic activity of the Cu-doped α-MnO2catalyst in the OSCO procedure by reducing ethylene production and maintaining the fruit quality during the preservation period.
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JOURNAL OF ENVIRONMENTAL MANAGEMENT
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2025
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IF 8.4
Yang Yu,Na Jiang,Yuanbo Zhou,Fei Huang,Yide He,Yongjun Zhang
Ofloxacin (OFX), commonly employed in the treatment of infectious diseases, is frequently detected in aquatic environments and poses potential ecological risks. UV/H 2 O 2 oxidation has been recognized as an efficient approach for removing antibiotics. In this study, Cu-doped waste-tire carbon was prepared and used as a UV/H 2 O 2 catalyst for the degradation of OFX. The results showed that the OFX removal was 89.3% within 90 min under the optimal reaction conditions. It was found that ZnO, used in the tire manufacturing to promote rubber vulcanization for enhanced stability and durability, played an important role in UV/H₂O₂ oxidation for OFX degradation. Toxicity experiments conducted with a microbial degradation respirometer demonstrated that the treated water exhibited low toxicity. This study introduces a sustainable catalyst derived from waste tires, and facilitating the development of metal-carbon catalysts for the effective removal of antibiotics from wastewater.
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TRANSITION METAL CHEMISTRY
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2024
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IF 1.6
Han Tianhang,Yao Kaisheng,Wang Zixu,Li Han,Zhao Haili
Nitroaromatic compounds are common toxic matters discharged as wastewater in varied industries. Reducing them into corresponding aromatic amines can not only decrease their contamination but also obtain value-added products, in which the preparation of catalysts with superior properties is the key. Herein, the spherical Cu-Ag architectures (ATs) are constructed via a two-step wet chemical method. First, the Cu microspheres are fabricated with the assistance of polyvinylpyrrolidone (PVP) in the mixed solution of ethylene glycol (EG) and water. Then, using them as templates, the spherical Cu-Ag ATs can be grown and constructed. The as-obtained Cu-Ag ATs have the spherical outlines assembled by many nanoparticles. The sliced Cu-Ag ATs show hollow structures and many nanothorns grow from the center to the around, combining the roughly spherical shell to build up the Cu-Ag ATs. In the reduction reaction of p -nitrophenol and p -nitroaniline, the spherical Cu-Ag ATs all exhibit excellent catalytic activities. Within 85 s and 80 s, the p -nitrophenol and p -nitroaniline can be converted completely. The prepared Cu-Ag ATs are expected to have potentials in other fields, such as electronics, sensors and so on. Graphical abstract The hierarchical Cu-Ag architectures are constructed successfully through a two-step wet chemical method, in which the rough Cu microspheres are first fabricated in aqueous EG solution, and are used as templates to direct the growth of Cu-Ag architectures. In both reduction of p -nitrophenol and p -nitroaniline, the Cu-Ag architectures exhibit high catalytic activities.
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JOURNAL OF CONTROLLED RELEASE
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2024
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IF 10.5
Yan Dai,Jiali Zhang,Shimeng Zhang,Linhua Li,Chao Qu,Jiang Chen,Lei Lu
Bacterial keratitis is a major cause of blindness, hindered by the rising threat of antibiotic resistance. Although corneal bandage lenses (CBLs) are widely utilized in ophthalmic treatment, their effectiveness in treating bacterial keratitis remains limited due to risks of secondary infections, patient discomfort, and complications. In this study, we developed a novel biomimetic coating on CBLs by grafting Ag/Cu bimetallic nanoparticles (Ag/Cu-NPs) and thiol-functionalized heparin (Hep-SH) using a rapid polydopamine (PDA) deposition technique, effectively mimicking the ocular surface glycocalyx structure. The resulting Ag/Cu-NPs/Hep-SH coated CBLs (PNH-CBLs) exhibited significant antibacterial activity, with over 80 % reduction in Staphylococcus aureus ( S. aureus ) and 70 % in Escherichia coli ( E. coli ) due to the sustained release of Ag + and Cu 2+ , along with displaying favorable in vitro biocompatibility. Animal experiments conducted on New Zealand white rabbits with bacterial keratitis demonstrated successful treatment therapeutic outcomes, with PNH-CBLs leading to a significant decrease in clinical score. These biomimetic lenses also exhibited selective anti-protein adsorption properties, minimizing inflammation and promoting surface lubrication. Overall, this innovative approach addresses critical challenges in antibiotic resistance and offers a promising therapeutic strategy for managing ophthalmic infectious diseases.
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BIOSENSORS & BIOELECTRONICS
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2024
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IF 10.7
Lin Fan,Lijun Kong,Hao Liu,Jiawei Zhang,Mengdi Hu,Li Fan,Hongliang Zhu,Shancheng Yan
Ag and Cu based nanostructures serve as advanced functional materials for biomedical applications , due to their unique properties. Here, we proposed a novel neurotransmitter biosensing method based on Ag–Cu composite nanozyme , synthesized through the soft film plate method. Supported by the soft film template , the Ag–Cu nanozymes were stably kept to an ultrafine 2D structure with high monodispersity, which provided a large specific surface area and sufficient binding sites , leading to controllable and improved dual-nanozyme activities over similar-sized mono-Ag and mono-Cu, and up to 4.95 times of natural enzyme-level. The multi-path enzymatic reaction processes catalyzed by Ag–Cu composite nanozymes were firstly theoretically discussed in detail, according to the theoretical redox potential of redox couples in the reaction systems. On this basis, the Ag–Cu filled nanonets based neurotransmitter biosensing is successfully applied in rapid detection for glutathione and dopamine, possessing a linear range of 10∼100 μM and 1–10 μM, and a detection limit of 3.01 μM and 0.29 μM, respectively, which exhibited superior performance for biomedical purposes over most commercially available products in speed and precision.
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Nature Communications
·
2025
·Vol. 16
·期 1
·1-11
·
IF 15.7
Wang Yi,Wang Shuo,Fu Yunfan,Sang Jiaqi,Wei Pengfei,Li Rongtan,Gao Dunfeng,Wang Guoxiong,Bao Xinhe
Renewable energy-driven electrocatalytic nitrate reduction reaction presents a low-carbon and sustainable route for ammonia synthesis under mild conditions. Yet, the practical application of this process is currently hindered by unsatisfactory electrocatalytic activity and long-term stability. Herein we achieve high-rate ammonia electrosynthesis using a stable amorphous/crystalline dual-phase Cu catalyst. The ammonia partial current density and formation rate reach 3.33 ± 0.005 A cm −2 and 15.5 ± 0.02 mmol h −1 cm −2 at a low cell voltage of 2.6 ± 0.01 V, respectively. Remarkably, the dual-phase Cu catalyst can maintain stable ammonia production with a Faradaic efficiency of around 90% at a high current density of 1.5 A cm −2 for up to 300 h. A scale-up demonstration with an electrode size of 100 cm 2 achieves an ammonia formation rate as high as 11.9 ± 0.5 g h −1 at a total current of 160 A. The impressive electrocatalytic performance is ascribed to the presence of stable amorphous Cu domains which promote the adsorption and hydrogenation of nitrogen-containing intermediates, thus improving reaction kinetics for ammonia formation. This work underscores the importance of stabilizing metastable amorphous structures for improving electrocatalytic reactivity and long-term stability.
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