CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Zhuogen Li,Gangqiang Zhu,Weibin Zhang,Lujun Zhu,Baowei Cao,Jianzhi Gao,Xianjin Shi,Yu Huang,Peng Liu,Mirabbos Hojamberdiev
In recent years, metal–semiconductor heterojunctions have been intensively researched in the field of photocatalysis due to the effective spatial separation of photo-induced electron-hole pairs. Here, the dual-functional copper (Cu 0 /Cu 2+ )-modified SrTiO 3-δ nanosheets (Cu/STCO) are successfully synthesized by a two-step route. First, Cu 2+ -doped SrTiO 3-δ (STCO) nanosheets are synthesized by a hydrothermal method and then Cu 0 nanoparticles (NPs) are in situ formed from the STCO under H 2 atmosphere at 500 °C. The optimized ratio 6 %-Cu/STCO photocatalyst exhibits the best photothermal catalytic performance for CO 2 reduction reaction (CO 2 RR) and H 2 evolution performance. The detailed characterization demonstrate that the Cu 2+ dopant extend the light absorption range and the in situ generated Cu 0 NPs effectively improve the separation ability of photogenerated charge carriers by forming the Schottky contact with STCO. The excited localized surface plasmon resonance (LSPR) effect of metallic Cu 0 in Cu/STCO shows a considerable catalysis performance even under 600 nm monochromatic light irradiation. The density functional theory (DFT) calculations suggest that the Cu/STCO diminishes the barrier of the rate-determining steps of the CO 2 RR and H 2 evolution thus perform the outstanding catalysis ability in two filed. This work presents the synergistic effect of Cu 0 and Cu 2+ on enhancing the photothermal catalytic performance for CO 2 RR and H 2 evolution and offers a novel strategy to synthesize the metal–semiconductor nanostructures for efficient harnessing of solar energy into fuel.
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高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2024
·
IF 4.3
Wenbo Lv,Yafang Song,Ruibin Guo,Nijuan Liu,Zunli Mo
Residual heavy metal ions in water pose a major hazard to ecology as well as human health, and Cu 2+ , as the most common heavy metal ion in water bodies, can cause a variety of diseases in human beings with prolonged exposure, therefore, a rational sensing platform is needed for the specific detection of Cu 2+ . In this work, based on the solvothermal method, we successfully prepared the composite UIO-66@FS by encapsulating the dye fluorescein sodium molecule (FS) with a metal–organic framework material (UIO-66). The composite material has bright fluorescence emission properties with a fluorescence quantum yield of 62.03 %, and the composite material has been used to construct a fluorescence sensing platform for detecting the heavy metal Cu 2+ in the aqueous environment. The fluorescence of UIO-66@FS can be greatly quenched by Cu 2+ , which is visible to the naked eye under UV lamp. The sensing platform is able to withstand environmental interference and has the advantages of high selectivity, excellent sensitivity, fast response, wide linear range (2.5 µM−500 µM), and low detection limit (0.246 µM) in the fluorescence quenching detection of Cu 2+ . In addition, the sensor has been used to detect Cu 2+ in real water samples with satisfactory recoveries. Therefore, this sensing probe can be an excellent candidate for Cu 2+ detection and has wonderful potential for real water sample detection.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2025
·
IF 9.7
Jiaying Chang,Man Wang,Junrong Wang,Guoqing Zhu,Yulin Xie,Yanrong Qian,Qianqian Sun,Chunxia Li
Autologous tumor cells demonstrate considerable promise as individualized therapeutic vaccines owing to their endogenous neoantigen repertoire. Nevertheless, their suboptimal immunogenicity substantially impedes clinical translation. Herein, we engineered an innovative whole tumor cell vaccine platform utilizing photothermal Cu 2- x Se nanoparticles, which encapsulate comprehensive tumor-associated antigens and intrinsic immunostimulatory molecules to elicit a polyvalent antitumor immune response. In this work, Cu 2-x Se was applied to prepare the whole tumor cell vaccine for the first time. As a pyroptosis inducer, Cu 2-x Se triggered the expression of damage-associated molecular patterns (DAMPs) as endogenous adjuvants in 4T1 cells (mouse breast cancer cells) under near-infrared (NIR) irradiation. Repeated freeze-thaw cycles inactivated and lysed Cu 2-x Se-loaded 4T1 cells, releasing DAMPs for laser-activated Cu 2-x Se-based whole tumor cell vaccine (LC-TCV) preparation. Mild photothermal therapy (PTT) at the vaccination site by NIR irradiation effectively suppressed tumor growth. This efficacy was primarily attributed to the synergistic effects of multiple natural antigens and adjuvants in LC-TCV, which promoted dendritic cells (DCs) maturation and subsequent immune activation. Consequently, it potentiates the recruitment of cytotoxic T lymphocytes, elicits immunogenic cell death (ICD), and consequently initiates a potent antigen-specific immune cascade. Collectively, this study presents an innovative approach to unleash the potential of personalized whole tumor cell vaccines in cancer therapy.
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高影响因子
Journal of Materials Chemistry A
·
2025
·
IF 9.5
Yijun Duan,Peizhen Yang,Shuo Zhang,Qinan Song,Yameng Li,Xiang Liu,Miao Li
Electrochemical conversion of nitrate (NO3−) in wastewater to valuable ammonia (NH3) under ambient conditions is a facile and competitive route for nitrate remediation. Cu-based catalysts are competitive candidates for the nitrate reduction reaction (NO3RR) but still face low NH3 faradaic efficiency and yield rate. Herein, we report a rational design of a tandem electrode, CoFe LDH/Cu2+1O NWs, fabricated by Cu2+1O nanowires (Cu2+1O NWs) covered with CoFe-layered double hydroxide (LDH) that exhibits NH3 faradaic efficiency and yield rate as high as 95.58% and 7.01 mg h−1 cm−2, respectively, under neutral conditions at −0.79 V vs. RHE. Combined with the in situ Fourier transform infrared spectroscopy and density functional theory calculations, the mechanism of NO3RR was revealed, and the contribution of heterogeneous structures to the tandem nitrate reduction process was further explained. The NO3− was preferably reduced to *NO2 on Cu2+1O NWs, and then the heterostructure CoFe LDH was associated with the combination of *H and intermediates which advanced the production of NH3. This work offers a new paradigm for constructing efficient, stable, and energy conservation transition metal composited electrocatalysts in the NO3RR.
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EUROPEAN POLYMER JOURNAL
·
2025
·
IF 6.3
Junqi Zhao,Zicheng Chen,Aijian Cao,Jiahao Huang,Suiping Deng,Jingxian Zhang,Langhuan Huang,Shaozao Tan
Bacterial infections pose a significant threat to the healing of human skin wounds, as the reactive oxygen species (ROS) they produce can significantly delay the wound healing process, ultimately leading to the formation of chronic wounds and even endangering human life. Therefore, this study successfully constructed a dynamically reversible hydrogel network through dual crosslinking of Schiff base bonds and hydrogen bonds using oxidized hyaluronic acid (OHA), carboxymethyl chitosan (CMCS), and tannic acid (TA). By loading Cu@PDA, the OCTC2 hydrogel wound dressing was prepared, exhibiting synergistic antibacterial and antioxidant properties through TA/Cu 2+ release and NIR-II photothermal effects. We used FTIR, XRD, SEM, and TEM to thoroughly analyse the specific composition and morphology of the Cu@PDA and hydrogel. We measured the injectability, adhesion, NIR-II photothermal, and antibacterial properties of each group of hydrogels. The results showed that TA and Cu@PDA endowed the hydrogel with excellent antioxidant properties, enabling effective scavenging of various free radicals. Additionally, OCTC2, which possesses sustained-release TA/Cu 2+ capability, achieves antibacterial rates of over 94 % against S. aureus and E. coli . Under the combined effect of NIR-II photothermal therapy, it can achieve highly efficient bacterial killing (99.8 %), effectively promoting the healing of bacterial infection wounds. OCTC2 holds promise as a potential ideal hydrogel dressing for treating bacterial-infected wounds.
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MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Hui Zhang,Jingqi Wang,Dejin Lin,Linfan Wang,Jiale Chen,Junjie Pan,Xiaofei Wang,Da Chen
The increasing persistence of harmful ions and pesticide residues has been a matter of concern due to their pernicious and ubiquitous impact on environmental processes. Herein, we design a ratiometric fluorescent platform for the cascade identification of Cu 2+ and glyphosate, which is devised by grafting rhodamine 6G onto F, N-doped carbon dots (F, N-CDs@Rh6G). The formation of F, N-CDs@Rh6G/Cu 2+ chelation complex induces fluorescence quenching at 438 nm, attributed to static complex formation and photoinduced energy transfer. Subsequently, the introduction of glyphosate reverses the binding priority of the chelated complex and results in the recovery of fluorescence signal at 438 nm, while the reference peak (558 nm) remains relatively stable. Under optimal conditions, the fluorescent probe exhibits the low detection limits (LODs) for Cu 2+ (61 nM) and glyphosate (53 nM). Additionally, a portable microcavity sensing platform combining with smartphone is devised for visual and on-site quantification of Cu 2+ and glyphosate with the exceptional LODs. Therefore, this newly microcavity with F, N-CDs@Rh6G provides a reliable cascade sensing platform for Cu 2+ and glyphosate determination, showcasing potential applications.
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SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
·
2025
·
IF 4.6
Taiyi Chen,Xiaoping Lin,Peisong Li,Wei Liu,Lu Jiang,Leyuan Huang,Zhongliang Li,Ruirui Zhu,Zhi-Liang Chen,Rongying Zeng,Mengqin Liu,Wen Chen
The precise detection of metal ions is crucial in food safety, biomedical diagnostics, and environmental monitoring. Although traditional “on-off” fluorescence probes are frequently utilized, their anti-interference capability remains a limitation. This study synthesized three new copper-based fluorescent probes: PTA, PTP, and PTD. Among them, PTD exhibited unique aggregation-induced emission (AIE) properties. PTD's remarkable selectivity for Zn 2+ was due to the formation of Zn 2+ -induced J-aggregates, which resulted in a concentration-dependent fluorescence redshift from green to yellow and then to red. Additionally, PTD demonstrated a rapid and sensitive response to Cu 2+ , and it was successfully integrated into a smartphone-based platform for the semi-quantitative detection of Zn 2+ and Cu 2+ in real food samples. The effectiveness in biological applications was also validated through live-cell imaging tests. This work contributes to the creation of highly selective and interference-resistant ratiometric fluorescence sensors by leveraging the special process of target metal ion-induced J-aggregate production in AIE-based probes.
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JOURNAL OF ALLOYS AND COMPOUNDS
·
2021
·
IF 5.316
Weiying Zhou,Fuwang Mo,Zishan Sun,Jiabao Luo,Jiaqi Fan,Hongni Zhu,Zhenpeng Zhu,Jinqing Huang,Xinguo Zhang
Carbon dots (CDs) with long-wavelength-emission and high quantum yield (QY) are the focus of current research, compared with widely-investigated blue-emitting CDs. Herein, bright red-emitting CDs were synthesized by hydrothermal reaction at 200 °C for 3 h. CDs prepared by p-Phenylenediamine (pPD) exhibits a weak red band at 635 nm under an excitation wavelength of 450 nm. Adding (NH 4 ) 2 HPO 4 and KBr as P and Br precursors, the red emission peak at 610 nm, which shows a peak blue-shift about 25 nm with a dramatic emission enhancement up to 20-folds by co-doping of P, Br atoms into CDs. The corresponding QY value of P, Br-doped CDs (P, Br-CDs) was greatly improved to 11.3% as compared to bare CDs’ (0.55%). Furthermore, P, Br-CDs show a remarkable luminescent turn-off response after adding copper ions (Cu 2+ ). In addition, the quenched luminescence of P, Br-CDs/Cu 2+ complex could be recovered by the chelation between Cu 2+ and L -cysteine ( L -Cys) after adding L -Cys. This fluorescence “ON-OFF-ON” protocol could be applied for sequent Cu 2+ and L -Cys detection, and offer a linear range of 0–150 μM and 0–100 μM with a limit of detection of 4.408 µM and 2.373 µM for Cu 2+ and L -Cys, respectively. All results indicate that P, Br-CDs are of great potential for further biological and environmental application.
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高影响因子
ANALYST
·
2019
·Vol. 144
·期 23
·6962-6967
·
IF 4.019
Guoxing Yin,Jingfeng Yao,Sai Hong,Yinuo Zhang,Zhaohua Xiao,Ting Yu,Haitao Li,Peng Yin
The monitoring of heavy transition metals has increasingly attracted great attention because they pollute the environment and have unique physiological functions. Chemosensors are useful tools for monitoring heavy transition metals due to their simple visualization, excellent sensitivity and high selectivity. Herein, we have developed a novel chemosensor for the detection of water-soluble Cu2+ and Ni2+ species with different mechanisms, and low detection limits of 2.1 nM for Cu2+ and 1.2 nM for Ni2+ were obtained. The colorimetric probe CPH has been applied to qualitative and quantitative detection of Cu2+ and Ni2+ species in real samples.
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Biomicrofluidics
·
2015
·Vol. 9
·期 2
·
IF 3.357
Li Yinbao,Yang Xiujuan,Chen Zuanguang,Zhang Beibei,Pan Jianbin,Li Xinchun,Yang Fan,Sun Duanping
Investigations were conducted to determine acute effects of Pb 2+ and Cu 2+ presented individually and collectively on zebrafish embryos. Aquatic safety testing requires a cheap, fast, and highly efficient platform for real-time evaluation of single and mixture of metal toxicity. In this study, we have developed a microfluidic system for phenotype-based evaluation of toxic effects of Pb 2+ and Cu 2+ using zebrafish ( Danio rerio ) embryos. The microfluidic chip is composed of a disc-shaped concentration gradient generator and 24 culture chambers, which can generate one blank solution, seven mixture concentrations, and eight single concentrations for each metal solution, thus enabling the assessment of zebrafish embryos. To test the accuracy of this new chip platform, we have examined the toxicity and teratogenicity of Pb 2+ and Cu 2+ on embryos. The individual and combined impact of Pb 2+ and Cu 2+ on zebrafish embryonic development was quantitatively assessed by recording a series of physiological indicators, such as spontaneous motion at 22 hours post fertilization (hpf), mortality at 24 hpf, heartbeat and body length at 96 hpf, etc. It was found that Pb 2+ or Cu 2+ could induce deformity and cardiovascular toxicity in zebrafish embryos and the mixture could induce more severe toxicity. This chip is a multiplexed testing apparatus that allows for the examination of toxicity and teratogenicity for substances and it also can be used as a potentially cost-effective and rapid aquatic safety assessment tool.
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ANALYST
·
2021
·Vol. 146
·期 18
·5668-5674
·
IF 4.616
Xiushuang Fan,Jinpeng Qiu,Chao Peng,Jiangtao Ren,Huanhuan Xing,Chuyao Bi,Jianyuan Yin,Jing Li
Monitoring the concentration of dopamine (DA) is vital for preventing and diagnosing DA related diseases. In contrast to the traditional sensing methods for DA, in which direct or indirect effects on the optical probes are often recorded, a novel sensing concept is disclosed based on as a result of the in situ formation of polydopamine (PDA) originating from the synergetic effect between boron nitride quantum dots (BNQDs) and Cu2+. In the co-presence of BNQDs and Cu2+, DA was catalytically oxidized to PDA, accompanied by an obvious color change from colorless to brown. In contrast to previous reports, in which BNQDs have been employed as an optical probe, herein, the BNQDs not only acted as the optical energy donor, but also as the catalysts for the formation of PDA. The quenching efficiency resulting from the inner filter effect and the electron transfer between the BNQDs and PDA was directly proportional to the concentration of DA, ranging linearly from 2 to 80 μM with a limit of detection of 0.49 μM. The present system exhibited an outstanding selectivity for DA among other interfering coexisting biomolecules. Furthermore, the practical application of the proposed platform was verified by assaying DA in human plasma samples, and satisfactory recoveries ranging from 101.24% to 111.98% were obtained. With the satisfactory reliability, repeatability and stability, the proposed simple sensor showed significant potential for use in DA detection in other biomedical applications.
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RSC Advances
·
2020
·Vol. 10
·期 55
·33299-33306
·
IF 3.119
Rentian Guan,Lixia Tao,Yingying Hu,Cong Zhang,Yongping Wang,Min Hong,Qiaoli Yue
In this work, a fluorescence method was developed for selective detection of Ag+ in the presence of Cd2+, Hg2+, and Cu2+ based on gold nanoclusters (AuNCs). That is, bovine serum albumin (BSA) templated AuNCs with double emission peaks were synthesized using BSA as a protective agent. AuNCs with uniform distribution and average size between 2.0 and 2.2 nm were synthesized using a green and simple method, and showed bright orange-red fluorescence under ultraviolet light. AuNCs have two emission peaks at 450 nm and 630 nm with an excitation wavelength of 365 nm. Under alkaline conditions, Cd2+ can combine with the surface sulfhydryl groups of BSA–AuNCs to form Cd–S bonds, which cause AuNCs to aggregate, resulting in an increase in fluorescence intensity at 630 nm. Conversely, due to the d10–d10 metal affinity interaction, the addition of Hg2+ can reduce the fluorescence peak at 630 nm. Ag+ was reduced to Ag0 by gold nuclei in AuNCs, forming a stable hybrid Au@ AgNCs species with blue-shifted and enhanced fluorescence. Finally, the paramagnetic behavior of Cu2+ combined with BSA causes the excited electrons of the gold cluster to lose their energy via ISC, eventually leading to simultaneous quenching of the two emission peaks. The results show that the limit of detection (LOD) of Ag+, Hg2+, Cd2+ and Cu2+ is 1.19 μM, 3.39 μM, 1.83 μM and 5.95 μM, respectively.
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