LWT-FOOD SCIENCE AND TECHNOLOGY
·
2021
·
IF 4.952
Chuan-Guo Ma,Man Zhao,Tian-Lei Si,Xiao-Wei Chen
Sea buckthorn ( Hippophaë rhamnoides L.) pulp oil (SPO) is enriched in natural bioactive components with high pharmacological activities. However, the presence of polysaccharides affects oil quality. Herein, the effects of different polysaccharide-adsorption treatments on the bioactive components and the in vitro antioxidant activities of SPO were investigated. The results demonstrated that the microwave-assisted activated clay (MAE-ACL) adsorption was more effective than the ultrasound-assisted activated clay adsorption for removing polysaccharides. Although the bioactive component levels and antioxidant activities of the SPO were reduced during the adsorption, the squalene content showed no significant difference. By performing principal component and correlation analyses that further evaluated the connection between the bioactive components and the free radical scavenging activities of SPO, MAE-ACL was determined to be the more suitable polysaccharide-adsorption treatment.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2020
·
IF 5.162
Yun-Tao Wu,Yun-Feng Huo,Lin Xu,Ying-Ying Xu,Xiao-Ling Wang,Tao Zhou
In order to study the antioxidant activity of Porphyra haitanensis polysaccharides and the effect of their structure on the antioxidant activity, the Porphyra haitanensis polysaccharide (PHP), prepared by hot water extraction and alcohol precipitation, was separated and purified by Cellulose DEAE-52 ion exchange and Sephadex G-100 column chromatography. Three purified components including PHP1, PHP2 and PHP3 were obtained, and chemical composition analysis and structural characterization were performed. The in vitro free radical scavenging activity of the purified polysaccharide fractions and their ability to relieve oxidative stress in macrophage RAW264.7 were investigated. The results indicated that all the three fractions possessed appreciable DPPH radical, superoxide anion radical, and hydroxyl radical scavenging ability and reducing power. They were also found to effectively reduce the MDA content and ROS level, and to improve the activities of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px) in H 2 O 2 -treated RAW264.7 cells. Among the three polysaccharides, PHP3 possessed the most potent activity. Porphyra haitanensis polysaccharides have potential to develop as natural non-toxic antioxidants and may find application as the ingredients of functional foods.
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PubMed
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FOOD HYDROCOLLOIDS
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2020
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IF 7.053
Shugang Li,Kangping Wang,Qun Huang,Fang Geng
The present study constructed a new gellable emulsion with the aid of microwave pretreatment to encapsulate pomegranate seed oil (PSO). The results showed that ovalbumin (OVA), inulin (IN) and carrageenan (κ-car) were adsorbed on the PSO drop surface to form an OVA–IN–PSO emulsion, and then, gelation of the emulsion occurred by heating with the assistance of microwave pretreatment. The properties of the OVA–IN–PSO emulsion gel, including the water holding capacity , fixed water ratio, texture properties, and rheological properties, were improved by microwave pretreatment. Microscopic observation confirmed that the OVA–IN–PSO gel was an oil-in-water type with a dense structure. Moreover, the denaturation temperature of the OVA–IN–PSO emulsion increased from 70.7 °C (0 min) to 76.3 °C (10 min). Benefitting from the protective effect of the OVA–IN–PSO gel, the stability of pomegranate seed oil was significantly improved. Lipid oxidation (peroxide value) and the loss of polyunsaturated fatty acids during pomegranate seed oil storage were suppressed. These results suggested that microwave pretreatment can improve the properties of OVA–IN–PSO gel as well as the oxidation stability of pomegranate seed oil.
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CARBOHYDRATE POLYMERS
·
2020
·
IF 7.182
Samah Attia Algharib,Ali Dawood,Kaixiang Zhou,Dongmei Chen,Chao Li,Kuiyu Meng,Muhammad Kashif Maa,Saeed Ahmed,Lingli Huang,Shuyu Xie
Due to the poor solubility and permeability of rifaximin (RFX), it is not effective against intracellular pathogens although it shows strong activity against most bacteria. To develop an effective mucoadhesive drug delivery system with a targeted release in bacterial infection site, RFX-loaded chitosan (CS)/carboxymethyl-chitosan (CMCS) nanogel was designed and systematically evaluated. FTIR, DSC, and XRD demonstrated that the nanogel was formed by interactions between the positively charged NH 3 + on CS and CMCS, and the negatively charged COO on CMCS. RFX was encapsulated into the optimized nanogel in amorphous form. The nanogel was a uniform spherical shape with a mean diameter of 171.07 nm. It had excellent sustained release, strong mucin binding ability, and pH-responsive properties of quicker swelling and release at acidic pH. It showed low hemolytic ratio and high antioxidant activity. The present investigation indicated that the CS-nanogel could be potentially used as a promising bacterial responsiveness drug delivery system.
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PubMed
高影响因子
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
·
2020
·Vol. 55
·期 9
·3082-3090
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IF 2.773
Yahya Saud Hamed,Mohamed Abdin,Guijie Chen,Hafiz Muhammad Saleem Akhtar,Xiaoxiong Zeng
Summary In an ultrasonic bath and for 30 min in the presence of water as extraction solvent in a ratio of 1:10 (g/mL), effect of extraction temperature on extraction of caffeoylquinic acids (CQAs) from Moringa oleifera leaves (MOL) was investigated. Gradually increasing in extraction temperature caused a growing in mono-CQA and declining in 3,5-diCQA. The extract obtained at 80 °C showed the highest antioxidant capacity, and IC 50 values for scavenging activities on DPPH radicals and ABTS radicals were 56.9 and 53.6 µg/mL, respectively. Compared with α-glucosidase and α-amylase, the extract showed the highest inhibition on pancreatic lipase (IC 50 of 0.073 mg/mL). Increasing the extraction temperature improved cytotoxicity of the extract on cancer cell lines of HeLa and HepG2. Compared with gram-negative Escherichia coli and Salmonella typhimurium , all the extracts showed higher inhibition on the growth of gram-positive Bacillus cereus and Staphylococcus aureus . Our results suggested that use of higher extraction temperature (80 °C) improved the biological activity of MOL extract.
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LWT-FOOD SCIENCE AND TECHNOLOGY
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2020
·
IF 4.006
Xiaoqin Wang,María del Mar Contreras,Dunming Xu,Chen Xing,Lijuan Wang,Daomao Yang
Bound phenolic compounds have been widely investigated in food from plants, while research on vegetable oils is limited. Thus, to comparatively analyse free and bound phenolic compounds in a lipid system, different distributions of free and bound phenolic compounds were prepared by exogenous addition of chemical standards to model tea seed oil in this work. For that, the phenolic composition was quantified with UHPLC-QqQ-MS/MS, and the antioxidant capacity was evaluated by the DPPH assay and the Rancimat method. After pre-optimisation of concentrations, the results showed that the oil sample contained 12.3% bound phenolic compounds after incubation for 6 h, higher than the other samples (0, 2, 4, 8, 10 and 12 h) with equal addition. This sample also had a longer reduction time during Rancimat oxidation, corresponding to the higher total DPPH radical scavenging capacity. Further, docking, molecular dynamics and quantum mechanics analysis revealed that intermolecular forces might account for binding forms between phenolic compounds and glycerides, including hydrogen bonds and hydrophobic interactions. In addition, the structure-activity relationship of bound phenolic compounds was explored tentatively. Conclusively, bound phenolic compounds in vegetable oil, probably formed by intermolecular interactions, enhanced antioxidant capacity, a novel perspective on the antioxidation in lipids.
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FOOD CHEMISTRY
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2020
·
IF 6.306
Yi-Ge Zhang,Huan Kan,Sheng-Xiong Chen,Kiran Thakur,Shaoyun Wang,Jian-Guo Zhang,Ya-Fang Shang,Zhao-Jun Wei
The phenols in Diaphragma juglandis fructus (DJF), walnut pellicle (WP), and flowers of Juglans regia (FJR) from walnut were extracted using three methods (methanolic condensation reflux extraction, ultrasonic wave extraction, and enzyme assisted-extraction), and phenolics and antioxidant capacities of different extractions were compared. Overall, 50 phenolics were identified by HPLC-MS/MS with 41 compounds in DJF, 32 in WP, and 29 in FJR. It was observed that tannins in WP was higher than those in DJF and FJR. As for PCA, more than 70% of the variance was explained with the obvious comparison between the phenolic constituents. The phenolics in walnut contributed to remarkable antioxidant effect, with the highest effect observed in WP. This study presents the analysis and comparison of the phenols can be further extended for the development of functional walnut instant foods.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2020
·
IF 3.99
Yanqing Wang,Qianqian Han,Ying Wang,Dan Qin,Qiang Luo,Hongmei Zhang
In this study, aromatic amino acid-conjugated chitosan are designed and developed, as viewed by multi-spectral methods. The results from 1H NMR , FTIR, and UV–vis indicated the successful grafting of tryptophan (Trp) or phenylalanine (Phe) onto chitosan (CS) to form Trp-CS and Phe-CS nano-conjugates with 4.7 % and 6.8 % grafting ratio. The grafting induced some influences on the chiral structure and the symmetry and backbone structure of CS. The thermal stability of Trp-CS and Phe-CS nano-conjugates is less than that of CS. Trp-CS and Phe-CS conjugates were formed as spherical nanoparticles . The rheological studies show that Trp-CS and Phe-CS exhibit characteristic of an elastic material. In addition, Trp-CS and Phe-CS present well antioxidant activities and good biocompatibility.
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ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
·
2020
·
IF 4.872
Xinwen Ding,Li Yang,Qi Guan,Hui Zeng,Chenwei Song,Jiayi Wu,Lihua Song
To investigate the effect of fermented black barley on cooking oil fume (COF)-induced lung injury, male ICR mice were randomized into five groups: normal control (NC), fermented black barley treatment (NF), COF exposure (O), COF + fermented black barley treatment (OF) and COF + Lactobacillus treatment (OL). The exposure of mice to COF was performed for 5 min per day and 4 days per week for a total of 9 weeks, and the mice in the OF, NF and OL groups were administered fermented black barley or Lactobacillus continuously for 9 weeks (1 mL/100 g). Our results showed that the gamma-aminobutyric acid (GABA), total phenolic, and flavonoid contents significantly increased after fermentation ( P < 0.01). In addition, fermented black barley significantly increased SOD activity in the lung tissue, decreased the wet pulmonary coefficient, inhibited the reduction of microbial diversity and richness, and upregulated genes involved in cilium assembly and the cilium axoneme. These findings support the notion that fermented black barley can ameliorate COF-induced lung injury in mice.
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Journal of Food Measurement and Characterization
·
2020
·Vol. 14
·期 4
·2010-2020
·
IF 1.648
Huang Shuai,Wang Qiang,Wang Yaosong,Ying Ruifeng,Fan Gongjian,Huang Meigui,Agyemang Mary
This study characterized the quality, composition and antioxidant activities of olive oil from four olive varieties grown in Chongqing, southwest of China. With the fruit skin turned from green to semi black, the percentage of oleic acid decreased while the percentage of linoleic acid increased. The highest concentrations of total phenolic content, total flavonoid content and total antioxidant activity were found in the Coratina olive oils, in which the lowest content of oleuropein was also observed. Significant differences of fatty acid composition at sn-2 position were observed among the varieties, with the percentage of oleic acid at sn-2 position in Picual olive oils were significantly higher than that of other varieties ( p < 0.05). In addition, the different varieties of olive oil samples were divided into three categories by principal component analysis (PCA), and the quality of Coratina olive oils were greatly affected by fruit ripening stage. With the fruit ripening, the levels of hydroxytyrosol, rutin, total phenolics, total flavonoids and antioxidant activities in Coratina olive oil all declined. This work can provide guidance for the harvesting time and processing of olives in Chongqing.
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FOOD HYDROCOLLOIDS
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2020
·
IF 7.053
Yu Hu,Chengxin He,Chengjia Jiang,Yang Liao,Hua Xiong,Qiang Zhao
Whey protein fibrils (WPF) formed at 6, 12, 18, and 24 h (80 °C, pH 2) and chitosan were utilized as vehicles to enhance curcumin dispersion stability at pH 3.5. Their antioxidant activity and release behavior in vitro were investigated. Compared with whey protein isolates (WPI), WPF possessed higher surface hydrophobicity and ζ-potential without reducing solubility. The solubility of curcumin was improved to 297.8 ± 3.3 μg/mL (400 μg/mL added) via complexation with chitosan and WPF-18 (WPF formed at 18 h). The hydrophobic groups of fibrils, rather than those exposed due to the hydrolyzed peptides, accounted for major binding sites of curcumin. Chitosan and fibrils combined with curcumin formed a bicontinuous polymer through electrostatic interaction and increased the repulsive force between fibrils, resulting in a delivery system with increased stability. Compared with curcumin alone, the complexes showed significantly improved antioxidant activity (DPPH radical scavenging activity and reducing power). Moreover, the delivery systems further provided opportunities for curcumin to release in the intestine. This potential vehicle may contribute further to introduce curcumin into fat-free acidic functional beverages.
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CARBOHYDRATE POLYMERS
·
2020
·
IF 7.182
Feng Shen,Haoquan Zhong,Wenjiao Ge,Junli Ren,Xiaohui Wang
Natural active compounds with antioxidant properties and other potential health benefits, like quercetin (Qu), have aroused wide concern for developing bio-functional products. However, their applications are hindered by their intrinsic poor water solubility and chemical instability. In this paper, a natural antioxidant alpha lipoic acid (ALA) was grafted onto chitosan (CS) to synthesize a novel graft polymer (CS-graft-ALA). In particular, this graft-polymer could self-assemble into spherical nanomicelles in water, with a low critical micelle concentration (CMC) of 0.0076 mg/mL. As a robust and active nanocarrier, the CS-graft-ALA micelles showed high efficiency in encapsulating Qu and dispersing Qu in water. As found, the antioxidant activity of Qu was effectively enhanced when entrapped within CS-graft-ALA micelles. Moreover, CS-graft-ALA micelles could significantly improve the photo-stability and temperature-stability of Qu. The Qu/CS-graft-ALA micelles with excellent water dispersability, stability and improved antioxidant activity hold a great potential for wide applications.
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