REACTIVE & FUNCTIONAL POLYMERS
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2026
·
IF 5.4
Blessing Gatsi,Sufeng Zhang,Yang Jin,Ang Lu
Hydrogels are unique biomaterials that have become vital for refractory wound healing. However, integrating facile, sustainable and crosslinker/initiator minimized synthesis processes while ensuring the hydrogels retain their mechanical integrity, and critical wound-healing functionalities is extremely challenging. In this study, we elaborately fabricated a cellulose nanofiber-reinforced (CNF) gelatin hydrogel assisted by curcumin modified nanoparticles (curAg) using a simple, yet effective strategy that utilizes the synergetic effects of coordinate covalent bonds, electrostatic interactions, and hydrogen bonds. Notably, the CurAg@G-CNF hydrogel exhibited remarkable mechanical strength (compressive strength, 119 kPa) and the interconnected microporous system that endowed the hydrogels with notable degradation rate (>70%) and swelling ratio of up to 1084%. Moreover, the CurAg@G-CNF hydrogel exhibited excellent cytocompatibility (cell viability >90%), hemocompatibility (hemolytic ratio < 5%), water retention (>90%), and noteworthy antibacterial properties. In-vivo wound healing analysis on a mouse skin wound model also demonstrated the distinctive ability of the CurAg@G-CNF hydrogel to improve wound closure which was evidenced by high upregulation of collagen aggregation, and vascularization, and epithelium regeneration. Overall, these multifaceted findings paves a way for the fabrication of natural bioresources-based materials for wound healing.
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高影响因子
Nature Communications
·
2026
·
IF 18.1
Shaojie Chen,Hao Tang,Xiaoliang Fan,Bohan Li,Yaomin Wang,Wei Zhou,Xiaoyu Jiang,Xiaomin Dong,Yanyi Wang,Peng Zhao,Tianwen Ye,Bolin An,Yijun Zheng,Chao Zhong
Bacterial cellulose possesses excellent biocompatibility and mechanical strength but lacks the bioactivity needed for many biomedical and healthcare applications. To address this limitation, we develop a metabolic glycoengineering–click chemistry strategy that enables in situ incorporation of azide groups into bacterial cellulose, followed by mild and selective conjugation of alkyne-bearing functional molecules. This approach avoids harsh chemical treatments, preserves the native properties of bacterial cellulose, and supports stable attachment of diverse bioactive agents, including antibacterial porphyrins, arginine-glycine-aspartic acid peptides, and recombinant proteins with fluorescent or enzymatic functions. As a proof-of-concept, a cascade catalytic system comprising glucose oxidase and superoxide dismutase is immobilized onto azide-modified bacterial cellulose, yielding a multifunctional wound dressing designed to address hyperglycemia and oxidative stress—key barriers to chronic wound healing. In male diabetic mice, this glucose oxidase/superoxide dismutase-integrated bacterial cellulose dressing (low endotoxin <0.1 EU/mL) accelerates wound closure to 92.1% by day 14, significantly outperforming the controls. Our strategy highlights a scalable and bio-orthogonal route for enhancing bacterial cellulose with user-defined bioactivities, thereby expanding its utility in advanced biomaterials development. Bacterial cellulose (BC) possesses excellent biocompatibility and mechanical strength but lacks the bioactivity needed for many biomedical applications. Here the authors use glycoengineering–click chemistry to incorporate azide groups into BC in situ, and show enhanced BC-mediated wound healing.
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PubMed
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2026
·
IF 3.1
Tingting Wang,Shirun Dong,Yulin Zhu,Wenbin Yang,Yongsheng Li,Fangfang He,Kai Zhang,Zhuoni Jiang
Cellulose-based hydrogels exhibit excellent optical transparency, biocompatibility, and flexibility, offering promising applications in biomedicine, energy-efficient buildings, and smart electronics. However, their practical use is limited by inherent drawbacks such as poor mechanical strength and fixed thermoresponsive range. In this study, we introduced poly(acrylic acid) (PAA) and CaCl 2 into the hydroxypropyl cellulose (HPC) hydrogel network to form a multiple dynamic crosslinking network, resulting in a synergistically toughened HPC-PAA-Ca 2+ thermochromic hydrogel with a tunable phase transition temperature range of 10°C–42°C. The photothermal regulation property enables its use in energy-efficient smart windows, demonstrating a cooling effect of 13.1°C in a model house. The mechanical performance of the hydrogel was enhanced by carboxyl-Ca 2+ coordination bonds, achieving a mechanical stress of 280 kPa, elongation of 460%, toughness of 0.56 MJ/m 3 , and excellent compression recovery (rebound rate > 95%). The incorporation of Ca 2+ also endows HPC-PAA-Ca 2+ hydrogel with high electrical conductivity of 1.48 S/m, enabling its use as a sensitive strain sensor capable of accurately monitoring human joint movements (elbow, wrist, and fingers). This work advances the development of multifunctional cellulose-based hydrogels and expands their potential applications in smart materials.
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高影响因子
Advanced Materials Interfaces
·
2026
·
IF 4.4
Wei Huang,Wuming Fan,Xinyan Fan,Yonggui Wang,Wenkai Zhao,Liang Li,Zefang Xiao,Yanjun Xie
Efficient fog harvesting strategies have attracted increasing attention for addressing global water scarcity. In this study, a bio-inspired slippery surface was engineered by combining hydrophilic–hydrophobic patterning and lubricant infusion based on hydrophobic undecylenic-modified microcrystalline cellulose (UMCC) nanoparticles. The UMCC nanoparticles were synthesized using a dialysis–spraying process, followed by UV-assisted patterning of the hydrophilic domains and infusion with a perfluoropolyether lubricant to create a stable, directionally modified slippery interface. The pristine nanoparticle surface exhibited strong adhesion and high contact-angle hysteresis, which severely hindered droplet removal. However, after lubricant infusion, the contact angle hysteresis was dramatically reduced, enabling rapid droplet mobility, similar to that of Nepenthes pitcher plants. The resulting surface exhibited excellent chemical and environmental stabilities over a wide pH range. Notably, the moderately hydrophilic amino-patterned surface enhanced droplet nucleation, coalescence, and directional removal, achieving an exceptional fog-harvesting rate of 532.8 ± 85.1 mg/(h·cm 2 ), surpassing the performance of all unmodified controls. This study established a simple and sustainable platform for next-generation bio-inspired fog-harvesting and water-management technologies.
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Green Energy & Environment
·
2017
·Vol. 3
·期 2
·138-146
·
IF 0
Meng Li,Yulong Wang,Xiaobang Hou,Xia Wan,Hui-Ning Xiao
Novel cellulose based flocculants C-g-P (DMC) with various chain architectures are synthesized through a situ graft copolymerization. The cationic ammonium chloride group (DMC) is grafted onto cellulose by two separate inverse emulsion polymerization with γ-methacryloxypropyl trimethoxy silane (KH-570) and double bond addition reactions, which is a new and simple method to employ KH-570 as a bridge for the connection of cellulose matrix and DMC group. The effects of pH, flocculant dose, standing time on turbidity of kaolin suspensions and particle sizes have been studied systematically. In addition, the response surface methodology (RSM) study confirms that PAC and C-g-P (DMC) have synergy in turbidity removal with a higher removal efficiency of 98.32%. Moreover, C-g-P (DMC) 1 has higher removal efficiency with 96.5% at a low dosage of 0.6 mg L −1 and better floc properties than C-g-P (DMC) 2 and C-g-P (DMC) 3 , suggesting that the length and quantity of cationic branch chains play a crucial role in Kaolin flocculation due to their dramatically enhanced bridging effects.
研究领域:
环境科学
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高分子化学
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水处理
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材料科学
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DOI
ACS Applied Materials & Interfaces
·
2021
·
IF 9.229
Fusheng Zhang,Wenna Ge,Cunli Wang,Xintong Zheng,Dongdong Wang,Xiancheng Zhang,Xue Wang,Xingya Xue,Guangyan Qing
Cellulose nanocrystals (CNCs) are powerful photonic building blocks for the fabrication of biosourced colored films. A combination of the advantages of self-assembled CNCs and multiple templating agents offers access to the development of novel physicochemical sensors, structural coatings, and optic devices. However, due to the inherent brittleness and water instability of CNC-derived materials, their further applications are widely questionable and restrictive. Here, a soft polymer of poly(vinyl alcohol) (PVA) was introduced into the rigid CNC system to balance molecular interactions, whereafter two hard/soft nanocomposites were fastened through a cross-linking reaction of glutaraldehyde (GA), resulting in a highly flexible, water-stable, and chiral nematic CNC composite film through an evaporation-induced self-assembly technique. For a 1.5 wt % GA-cross-linked 70 wt % CNC loading film, its treatment with harsh hydrophilic exposure (soaking in a strong acid, strong base, and seawater) and various organic solvents show exceptional solvent-resistant abilities. Furthermore, the film can even withstand a weight of 167 g cm–2 without failure, which is a highly stiff and durable character. Importantly, the film remains a highly ordered chiral nematic organization, being able to act as a highly transparent substrate for selective reflection of left-handed circularly polarized light, preparing fully covered and patterned full-color coatings on various substrates. Our work paves the way for applications in low-cost, durable, and photonic cellulosic coatings.
研究领域:
材料科学
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纳米技术
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光子学
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高分子科学
·
可持续材料
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高影响因子
FOOD CHEMISTRY
·
2015
·
IF 3.391
Yuehan Wu,Xiaogang Luo,Wei Li,Rong Song,Jing Li,Yan Li,Bin Li,Shilin Liu
In order to obtain a safe and biodegradable material with antimicrobial properties from cellulose for food packaging, we presented a facile way to graft chitosan onto the oxidized cellulose films. The obtained films had a high transparent property of above 80% transmittance, excellent barrier properties against oxygen and antimicrobial properties against Escherichia coli and Staphylococcus aureus. The antimicrobial properties, mechanical properties, and water vapor permeability of composites are essential characteristics in determining their applicability as food-packaging materials. Moreover, using a sausage model, it was shown that the composites exhibited better performance than traditional polyethylene packaging material and demonstrated good potential as food packaging materials. The results presented a new insight into the development of green materials for food packaging.
研究领域:
材料科学
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食品包装
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聚合物复合材料
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绿色材料
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抗菌技术
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高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2022
·
IF 8.025
Yuxia Luo,Zhuo Chen,Ping He,Qingdi Liu,Zemin He,Yuzhen Zhao,Hao Ma,Liyi Li,Zhao Zhang,Xinping Li,Qing Han
A new design for chiral photonic cellulose nanocrystal films was developed by co-assembling lanthanide-doped nanorods (NRs) into chiral cellulose nanocrystals, in which the photonic band gap (PBG) could be tuned in the visible range by changing the mass fraction of flexible agents, such as polyvinyl alcohol (PVA) and ethylene glycol (EG). Due to the PBG effect, the luminescence modulation in such nanocrystal films had been realized. The down-conversion luminescence from NaGd 30 Y 60 F 4 :5%Tb 3+ , 5%Eu 3+ NRs and up-conversion luminescence from NaGd 40 Y 40 F 4 :18%Yb 3+ , 2%Er 3+ NRs could be enhanced by 28 % and 18 % respectively, on account of the band edge effect. The luminescence would be inhibited when the luminescence overlapped with the stop band of the PBG. These results implied that the biocompatible photonic cellulose nanocrystal films are ideally suited for applications in optical coding, optical resonators and biocompatible lasers.
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PubMed
高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2022
·Vol. 415
·期 18
·4245-4254
·
IF 4.478
Zhang Jing-Jing,Wang Si-Ying,Dai Hai-Tao,Li Hai-Chao,Wang Yong
Chiral recognition is an emerging field of modern chemical analysis, and the development of health-related fields depends on the production of enantiomers. Cellulose is a kind of natural polymer material with certain chiral recognition ability. Limited by the chiral recognition ability of natural cellulose itself, more cellulose derivatives have been gradually developed for chiral recognition and separation. Based on the difference in action between cellulose derivatives and enantiomers, this work synthesized cellulose-tris(4-methylphenylcarbamate) (CMPC) chiral recognition mediators and a CMPC-functionalized extended-gate organic field effect transistor (EG-OFET) was constructed for the first time. Three chiral molecules were selected as model analytes to evaluate the enantiomeric recognition ability of the platform, including threonine (Thr), 2-chloromandelic acid (CA), and 1,2-diphenylethylenediamine (DPEA). The detection limit for 1,2-diphenylethylenediamine (DPEA) is down to 10 −13 M. Through the amplification effect of the EG-OFET platform, the difference in the interaction between CMPC and three chiral molecules with different structures is converted into a current signal output. At the same time, the enantiomer discrimination mechanism of CMPC was further studied by means of spectroscopy and nuclear magnetic resonance. Graphical abstract
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CELLULOSE
·
2023
·Vol. 30
·期 4
·2399-2412
·
IF 5.7
Li XiaoJuan,Zhang Ying,Chen Junfeng,Wang Yanan,Cheng Zhuoying,Chen Xueqi,Guo Minghui
Solid flexible electrolyte plays important roles in flexible supercapacitors. However, their low ionic conductivity and mechanical stability restrict their applications. Therefore, the development of flexible solid electrolytes with excellent mechanical properties and electrochemical performance is highly desirable. In this work, a cellulose-polyacrylamide double network hydrogel electrolyte was prepared by a simple method, with cellulose as the first network layer and polyacrylamide as the second network layer. The ionic conductivity of the resulting material reached 131.4 mS cm −1 . The dual network endowed the hydrogel electrolyte with abundant ion channels and excellent mechanical stability, effectively reducing the interfacial contact resistance with the electrode. The activated carbon-based supercapacitor with cellulose-Polyacrylamide interpenetrating network hydrogel electrolyte delivered high specific capacitance of 989 mF cm −2 at 2 mA cm −2 . Besides, the electrochemical behavior of the supercapacitor showed no obvious differences from supercapacitors assembled with aqueous electrolytes. The excellent adhesion and flexibility of hydrogels allowed the supercapacitors to cope with deformation and compression at various angles while maintaining stable electrochemical behavior. In summary, the proposed approach is promising for the development of flexible energy storage devices with good electrochemical and mechanical stability.
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Nano Energy
·
2023
·
IF 17.6
Wanglin Zhang,Xianghui Chen,Jiamin Zhao,Xinyue Wang,Xiuzhen Li,Tao Liu,Bin Luo,Ying Qin,Song Zhang,Mingchao Chi,Shuangfei Wang,Shuangxi Nie
Triboelectric nanogenerators (TENGs) have ideal applications in the field of self-powered sensing thanks to their simple structure and flexible working mode. However, the weak operating properties of triboelectric materials in high humidity environments limit the wide application of TENG as sensors. To solve this problem, this work prepared hydrophilic triboelectric materials with natural cellulose as the template and used them for self-powered sensing in high humidity environments. Thanks to the interconnected network of the cellulose scaffold, the complex morphology of the material constructed in concert with Ti 3 C 2 T x during templating provides abundant adsorption sites for water molecules. Over a broad humidity range (40%−90% relative humidity (RH)), the moisture-sensitive triboelectric material can sustain outstanding performance in 150 s with high sensitivity (0.8/1%). The cellulose template-based triboelectric material transmits electrical signals to the user interface wirelessly, enabling self-powered sensing in high humidity environments. This study provides a novel strategy for the design and preparation of high-performance triboelectric materials using cellulose as a template and promotes the study of self-powered sensing in high humidity environments.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2023
·
IF 8.6
Zhipeng Zhang,Xiansong Shi,Xingyuan Wang,Zhe Zhang,Yong Wang
Efficient capture and storage of radioiodine are of great importance for developing nuclear energy and tackling nuclear waste, which however remain challenging due to the scarcity of powerful materials. In this work, we rationally design and fabricate a hybrid material by encapsulating covalent organic frameworks (COFs) into ultralight cellulose aerogels for efficient iodine (I 2 ) capture. Two kinds of functionalized cellulose precursors that can be covalently cross-linked are synthesized. Solvothermally synthesized COF particles with a uniform diameter of ∼ 500 nm are then introduced into the precursors followed by freeze drying to produce hybrid aerogels. With the presence of rich and ordered micropores afforded by COFs, these highly porous aerogels exhibit excellent organic solvent absorption performances and high uptake capacities toward solvent-dissolved and vaporized I 2 . More importantly, in view of the processable and robust structure, we realize the shaping of hybrid aerogels into aerogel columns to effectively capture I 2 vapor and I 2 solute in continuous operations. Therefore, this work not only provides a new way to shape COF materials but also could inspire the design of viable platforms for high-performance I 2 capture.
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高影响因子
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