CHEMISTRY-A EUROPEAN JOURNAL
·
2022
·Vol. 28
·期 66
·e202202256
·
IF 5.02
Niuniu Zhang,Xia Wu,Kangjia Lv,Yujie Chu,Haimei Qin,Dongdi Zhang,Guan Wang,Jingyang Niu
Graphical An excellent 2D photocatalyst was synthesized by loading Au nanoparticles and CdS quantum dots on niobate nanosheets. This CdS/Au/HNb 3 O 8 photocatalyst not only increased the photocatalytic hydrogen evolution rate by 254 times compared with the pure niobate nanosheet, but also showed outstanding photocatalytic performance for oxidative self-coupling of benzylamine and degradation of organic dyes. Niobate nanosheets have aroused widespread interest in recent years for their prospects in catalysis. The exploration of 2D niobate catalysis with stable and efficient properties is still the focus in chemistry and materials science. Herein, the successful fabrication of 2D CdS/Au/HNb 3 O 8 catalyst is demonstrated which revealed efficient photocatalytic properties in H 2 evolution, oxidative self-coupling of amines to imines, and degradation of dyes. Especially the assembled architecture can give a rate of 5.85 mmol ⋅ g −1 ⋅ h −1 of photocatalytic H 2 evolution, an ∼254-fold enhancement, compared with bare HNb 3 O 8 nanosheets under identical conditions. In accordance with density functional theory (DFT) and X-ray adsorption fine structure (XAFS) analyses, the vast improvements are benefited from efficient migration and separation of charge carriers. Besides, the surface plasma resonance (SPR) effect of Au NPs enhances the light harvesting capacity and boosts the generation of hot electrons, efficiently improving the visible-light absorption.
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TALANTA
·
2020
·
IF 5.339
Yueyue Tian,Yancao Chen,Mei Chen,Zhi-Ling Song,Bin Xiong,Xiao-Bing Zhang
Here we report the peroxidase-like [email protected] nanozyme as an integrated nanosensor for selective detection of silver ions (Ag + ), where the nanozyme plays the roles as both the signal trigger and reporter simultaneously. This method relies on two critical chemical reactions, including (1) the unique inhibitory effect of Ag + on the nanozyme triggered H 2 O 2 decomposition at weak acid environment and (2) H 2 O 2 induced Ag + reduction onto the nanozyme surface at basic environment, leading to a blueshift in the localized surface plasmonic resonance wavelength (LSPR λ max ) of the nanosensor. With this simple strategy, we demonstrated the sensitive and selective detection of Ag + over a dynamic range from 0.5 to 1000 μM with a limit of detection (LOD) of 500 nM by UV–visible spectroscopy, which is below the permitted level of Ag + in drinking water by U.S. Environmental Protection Agency (EPA). This method also exhibits satisfying recovery efficiency for Ag + detection both in tap water and spring water from the Yuelu Mountain. With this satisfying sensing performance and excellent stability of nanoprobes, this strategy is promising for the detection of Ag + in environment monitoring and food safety analysis.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2026
·
IF 9.6
Zhiming Chen,Jiabin Chen,Haoming Bao,Kaitao Liu,Pan Zeng,Fan Yang,Wei Cao,Dongqi Yang,An Cao,Tao Zhang,Yue Li
Surface-enhanced Raman scattering (SERS) has been one of the efficient strategies for trace molecular analysis, but the traditional substrates with sharp tips cannot effectively detecting the molecular isomers. Here, we develop a facile way to fabricate large-area, reproducible Ag/Au nanocavity arrays by the combination of microsphere-templated soft lithography and self-assembly. Compared to the flat and convex substrate, the Ag/Au units arranged on the concave surface exhibit a high-density of hotspots via spatial light confinement and multi-reflection-enhanced electromagnetic coupling, which enables highly sensitive detection of probe molecules down to10 −12 M. Moreover, by integrating machine learning algorithms, the test set shows a coefficient of determination (R 2 ) of 0.9896, achieving advanced training performance for classifying four structurally analogous quinolone antibiotics (ciprofloxacin, enrofloxacin, danofloxacin, and enoxacin) with a quantitative prediction of 10 −10 M. This work demonstrates a robust pathway for the controllable fabrication of high-performance SERS substrates for the development of intelligent, quantitative, and on-site sensing platforms in complex practical scenarios. Download: Download high-res image (179KB) Download: Download full-size image
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LANGMUIR
·
2026
·Vol. 42
·期 29
·21638-21647
·
IF 4.4
Shu Yu,Zhao Chun,Tang Gangqiang,Zhao Xin,Jiang Mingfei,Zhang Weiwei,Wang Yanjie
Ionic polymer–metal composite (IPMC) integrates
ionic conductivity
and flexibility, exhibiting great application potential in wearable
devices, bionic robots, microfluidic chips and other fields. Although
the thickness of the electrode layer of IPMC fabricated by traditional
physical methods is controllable, it fails to achieve high compactness,
strong adhesion and low sheet resistance, resulting in performance
far inferior to that of IPMCs prepared by chemical methods. To address
the above issues, this work proposes a new strategy with controllable
electrode layer thickness based on spraying silver nanoparticles (AgNPs)
and electroplating (EP), which effectively enables the rapid construction
and performance enhancement of the electrode layer. Compared with
IPMCs prepared by other processes, the IPMC with sprayed AgNPs@Au
electrodes shows advantages of low sheet resistance (∼0.115
Ω/□) and high sensitivity (∼8.475 mV/cm –1 ). Meanwhile, it maintains high stability after 1000 cyclic bends
or immersion in HCl for corrosion, further demonstrating the potential
application of IPMCs prepared by this process in flexible wearable
sensors.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2026
·
IF 8.3
Fan Feng,Haicheng Gao,Yuan Xue,Qing Dong,Junfeng Zhai,Dan Li,Erkang Wang,Jin Wang
Exosomes, as extracellular vesicles, represent ideal biomarkers for liquid biopsy, enabling non-invasive, sensitive, and dynamic disease monitoring. Detection or profiling of exosomes are essential for advancing exosome-based cancer diagnostics or prognostic prediction. Here, we developed an enhanced electrochemiluminescence (ECL) biosensing platform that combines magnetic enrichment with catalytic hairpin assembly (CHA), an enzyme-free DNA amplification circuit triggered by the complementary sequences of CD63 aptamer (Apt), to achieve sensitive exosome detection. The enhanced ECL signal relies on a nanocomposite of a zirconium-based metal-organic framework (Zr-MOF) and water soluble gold nanoclusters (AuNCs), denoted as Zr-MOF/AuNCs. The platform exhibits a wide linear range (6.12 × 10² - 6.12 × 10⁷ particles/mL) and a low detection limit (187.4 particles/mL) for tumor-derived exosomes. Spike-recovery assays in complex serum matrices and high specificity confirm its robustness and clinical potential. By combining magnetic preconcentration, signal amplification via Zr-MOF and CHA, and Apt-mediated recognition, this work establishes a new paradigm for non-invasive cancer diagnostics.
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CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Yujie Ma,Xianning Yang,Jing Yu,Kun Wang,Xiang Li,Xinyi Liang,Seunghyun Lee,Haijiao Xie,Jingbin Zeng
Rapid, synchronous, and quantitative detection of interleukin-6 (IL-6) and procalcitonin (PCT) is of great significance for the early diagnosis of infectious diseases, yet it remains a formidable challenge for conventional lateral flow immunoassays (LFIAs) due to their inherent semi-quantitative nature and limited sensitivity. Herein, we tackle this challenge through the rational design of dumbbell-shaped Au/end-CeO 2 heterojunctions, where the site-specific deposition of CeO 2 on gold nanorods creates a Schottky interface that profoundly modulates carrier dynamics. This unique architecture effectively suppresses electron-hole recombination and enhances localized electromagnetic fields, yielding an exceptional photothermal conversion efficiency of 58.22%—a 39.3% increase over pure Au nanorods. Capitalizing on this advanced nanomaterial, we engineer a colorimetric/photothermal dual-mode LFIA platform. This platform not only achieves ultrasensitive individual detection of IL-6 and PCT with detection limits as low as 44 and 52 pg·mL −1 , respectively, but also realizes their efficient synchronous co-detection in a single, rapid chromatography step. By integrating visual colorimetric screening with quantitative photothermal readout, this work establishes a material foundation and technical pathway toward highly sensitive, quantitative LFIA systems, providing a referential approach for rapid screening in settings where access to large-scale instrumentation is limited.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2026
·
IF 8.3
Bingxi Feng,Zizheng Wang,Yuan Yao,Yonghui Deng,Jing Wei
Noble metal nanosensitizers such as Pt and Pd are widely employed to enhance the H 2 sensing performance of semiconductor metal oxide gas sensors owing to their superior capability for H 2 adsorption and dissociation; however, they exhibit poor resistance to CO, a gas that commonly coexists with H 2 , leading to cross-response and false alarms in real-world application scenarios. In this work, we design a wireless gas sensor based on Au nanocluster-functionalized SnO 2 nanosheets. The sensor exhibits exceptional sensitivity (43.2 ppm -1 ), a low detection limit (100 ppb), rapid response time (11 s), excellent selectivity, and strong anti-interference capability against CO. Notably, owing to their ultra-small particle size and high catalytic activity, the Au nanocluster-functionalized SnO 2 nanosheets show a response 51.1 and 1.6 times higher than that of pristine SnO 2 and conventional Au nanoparticle-functionalized SnO 2 nanosheets. Moreover, when CO at a concentration 60 times higher than H 2 is introduced into the H 2 stream, the sensor response changes by only 7.8%. Furthermore, a handheld detector is developed for hydrogen leak detection and early warning. This work presents an alternative strategy for the fabrication of high-performance H 2 sensors with superior CO resistance by employing gold nanoclusters as a sensitizer in place of conventional Pd-based materials.
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CHEMICAL ENGINEERING SCIENCE
·
2026
·
IF 5.1
Yun Qin,Li Zhang,Yu Ren,Yihao Wu,Yiping Wu,Ying Wen,Xinling Liu,Xiaoyu Guo,Haifeng Yang
Rational design of a multifunctional mSiO 2 -CQDs-Au@Ag nanocomposite. • Au@Ag and CQDs synergistically strengthen the SERS response. • The substrate achieves an enhancement factor of 1.0 × 10 9 . • Amisulpride in seawater is detected at 6.1 × 10 −9 mol·L −1 . • Charge transfer assisted enhancement is revealed experimentally. Pharmaceutically active compounds (PhACs) are receiving increasing attention because of their widespread use and continuous release into aquatic environments. Among them, amisulpride (AMI), a widely prescribed antipsychotic drug, is a plausible aquatic contaminant due to its release through wastewater and incomplete metabolic removal. Herein, Au@Ag core–shell nanoparticles were prepared using β-cyclodextrin as both the reducing agent and stabilizer, and further assembled with carbon quantum dots (CQDs) and mesoporous silica (mSiO 2 ) to construct a composite Surface-enhanced Raman scattering (SERS) substrate, mSiO 2 -CQDs-Au@Ag, for sensitive AMI detection. The substrate exhibited strong enhancement capability, with an enhancement factor (EF) as high as 1.0 × 10 9 . When applied to the detection of AMI in seawater, the proposed platform achieves a low limit of detection (LOD) of 6.1 × 10 −9 mol·L −1 , together with a good linearity (R 2 = 0.993). Combined theoretical and experimental analyses indicated that CQDs not only participate in interfacial charge transfer, but also contribute to analyte adsorption. This work offers a rational strategy for constructing semiconductor-integrated SERS platforms for sensitive detection and demonstrates its promising potential for environmental monitoring of emerging organic pollutants. Download: Download high-res image (91KB) Download: Download full-size image
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JOURNAL OF NANOBIOTECHNOLOGY
·
2026
·
IF 15
Wang Bo,Xiang Qingming,Luo Baiyi,Zhao Yu,Chen Junyang,Xie Yingling,Xu Yu,Tian Jian
Radiotherapy (RT) efficacy is constrained by inefficient radiation utilization and inadequate systemic immunity. Although nanoparticle-based radiosensitizers aim to enhance therapeutic outcomes, most existing systems lack effective integration of radiation enhancement, dynamic therapy, and systemic immune activation. Herein, we report Au@HOF, a core-shell nanoradiosensitizer synthesized via a facile one-pot strategy, comprising a gold core and a porphyrin-based hydrogen-bonded organic framework (HOF) shell. This unique architecture enables synergistic radio-radiodynamic therapy (RT-RDT) and robust immunogenic cell death (ICD) activation. The gold core enhances radiosensitization through efficient X-ray absorption and secondary electron emission in RT, while concurrently acting as a scintillator to activate the porphyrinic HOF shell for potent singlet oxygen (¹O₂) generation during RDT. The resulting RT-RDT synergy significantly amplifies reactive oxygen species production, intensifying oxidative stress to trigger potent ICD. This ICD cascade remodels the immunosuppressive tumor microenvironment, promoting T-cell infiltration and enhancing cancer immunotherapy. When combined with immune checkpoint blockade, Au@HOF elicits strong abscopal effects, suppressing both primary and metastatic tumors. Furthermore, Au@HOF serves as an effective contrast agent for computed tomography-guided tumor localization and radiation dose planning. Collectively, Au@HOF represents a precision nanoplatform that intelligently integrates enhanced RT-RDT with ICD-driven systemic antitumor immunity, providing a transformative strategy against advanced malignancies. Graphical
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Materials Today Advances
·
2026
·
IF 8
Xiao Wang,Yanan Ren,Yuhao Yang,Hui Tu,Dandan Fan,Yuchuan Zhuang,Jing Li,Yanbo Dong,Andrey Tulupov,Ying Hu,Yong Zhang,Jianfeng Bao
The accelerating global crisis of multidrug-resistant infections and the physical intractability of dense bacterial biofilms demand therapeutic platforms that are both functionally active and externally controllable. Here we report the rational design and synthesis of a fuel-free, near-infrared (NIR) propelled Janus nanomotor, PCN-224@Au, that unites photothermal therapy (PTT) with sonodynamic therapy (SDT) in a single construct. Asymmetric deposition of gold onto a porphyrinic PCN-224 metal-organic framework (MOF) establishes the geometric anisotropy required for propulsion and a metal–MOF interface that promotes charge separation. Under low-power 808-nm irradiation, the Au cap converts light to heat and drives self-thermophoretic motion, yielding directed transport with ensemble speeds of ∼10 μm s −1 and super-diffusive MSD of ∼60 μm 2 at 4 s while producing a local temperature rise of 35 + °C within 600 s at 100 μg mL −1 . Ultrasound (US) activates ROS formation in PCN-224, and the Janus architecture simultaneously delivers NIR photothermal input to amplify the effect. Dual activation with NIR and US therefore delivers localized thermal stress (PTT) together with high ROS flux (SDT), producing broad-spectrum antibacterial effects against methicillin-resistant Staphylococcus aureus (MRSA) and Escherichia coli (E. coli) . Light-driven motility enhances deep biofilm penetration and nanomotor-bacteria contact, while US-activated ROS disrupt membranes and trigger cytoplasmic leakage, translating into rapid, depth-resolved sterilization with favorable hemocompatibility and cytocompatibility. By coupling controllable propulsion with sonocatalysis, this Janus nanomotor approach overcomes transport and resistance barriers and provides an effective, fuel-free platform for broad-spectrum antibacterial therapy.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2026
·
IF 9.6
Chenyi Zhang,Zhenyu Wan,Jiangjie Zhang,Jinni Shen,Chengwei Qiu,Wenxin Dai,Zizhong Zhang
Dual-site Au/Ta-TiO 2 photocatalyst was designed to photocatalytic oxidative coupling of methane. • The incorporation of Ta as an n-type dopant TiO 2 , promoting the reduction of molecular oxygen to superoxide radicals (O 2 • − ). • Au nanoparticles effectively promoted C C coupling. • Au 1wt% /Ta 0.03 -TiO 2 achieved an ethane production rate of 25 mmol∙g −1 ∙h −1 with a C 2+ selectivity of 83%. The photocatalytic oxidative coupling of methane (OCM) offers a promising green route for carbon utilization but is hindered by low conversion rates and over-oxidation. Herein, we engineer a dual-site Au/Ta-TiO 2 photocatalyst that achieves high-performance OCM. The incorporation of Ta as an n-type dopant effectively modulates the electronic structure of TiO 2 , providing abundant localized electrons that promote the reduction of molecular oxygen to superoxide radicals (O 2 • − ). It subsequently participates in the oxidative cycle, ultimately regenerating water and thereby enhancing CH 4 activation. Meanwhile, Au nanoparticles serve as sites for methyl radical coupling, curbing over-oxidation. The concerted catalysis on these two sites leads to outstanding OCM performance. An optimized Au/Ta-TiO 2 catalyst yields a methane conversion rate of 25 mmol∙g −1 ∙h −1 and 83% selectivity towards C 2+ products in a flow reactor that exceeds most reported photocatalysts. This work provides new insights into achieving high-performance photocatalytic methane conversion by precisely driving oxygen activation. This work designs a Ta-doping and Au-loading dual-site TiO 2 photocatalyst to improve the selective conversion of methane to ethane under aerobic conditions for sustainable chemical production. Download: Download high-res image (133KB) Download: Download full-size image
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ChemSusChem
·
2026
·Vol. 19
·期 4
·e202502442
·
IF 5.9
Wanchuan Jin,Aoyun Wang,Xinhua Li,Yuxin Wang,Yuanhong Liu,Ruishi Xie,Rongrong Luo,Yuanli Li
Photocatalytic hydrogen peroxide (H 2 O 2 ) production is a promising green and sustainable approach, but achieving high efficiency in pure water systems without the sacrificial agents remains a significant challenge. Here, gold (Au) nanoparticles with varying loadings are photodeposited onto the surface of ZnIn 2 S 4 (ZIS) nanoflowers to enhance photocatalytic H 2 O 2 production. The optimized Au 1000 -ZIS sample achieves an exceptional H 2 O 2 production rate of 906.13 µmol g −1 h −1 under pure water conditions, along with outstanding cycling stability. Mechanistic studies reveal that multivalent Au nanoparticles serve as efficient electron trapping sites, thereby significantly enhancing the spatial separation of photogenerated charge carriers and facilitating rapid charge transfer. This enhanced charge transfer kinetics facilitates H 2 O 2 photosynthesis through a dual-channel process (2-electron oxygen reduction and water oxidation) without any additional sacrificial agent. This study enhances the understanding of the critical role of Au as a cocatalyst in photocatalytic processes and presents a promising strategy for sustainable and efficient H 2 O 2 production. Graphical Multivalent Au nanoparticles loaded onto ZnIn 2 S 4 nanoflowers have been constructed to effective H 2 O 2 photosynthesis from pure water without sacrificial agents, in which Au cocatalysts act as an electron trap, boosting accelerated electron transfer kinetics and enabling a dual-channel oxygen reduction reaction/water oxidation mechanism, achieving a high yield of 906.13 µmol g −1 h −1 .
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