CELLULOSE
·
2021
·Vol. 28
·期 8
·4959-4973
·
IF 5.044
Wang Dong,Lin Junkang,Huang Jianhua,Zhang Hui,Lin Shan,Chen Lihui,Ni Yonghao,Huang Liulian
A major obstacle for the development of the cellulose-based nanofiltration membrane is its fouling. In this study, a novel cellulose-based composite nanofiltration membrane (CS/DA-TiO 2 -NFM) with excellent anti-fouling performance was prepared through casting of both chitosan (CS) and TiO 2 modified by dopamine (DA-TiO 2 ) on the cellulose substrate membrane. DA-TiO 2 was successfully introduced into the surface of membrane, resulting in significant improvement in its hydrophilicity due to the formation of dense CS layers. Furthermore, both CS and DA-TiO 2 were effective antimicrobial agents (against E. coli 90.6% and S. aureus 95.1%) that could minimize the accumulation of bacteria on the CS/DA-TiO 2 -NFM. For the antifouling test against BSA, the irreversible recovery ratio of the CS/DA-TiO 2 -NFM was only 23.25% of the control (no CS/DA-TiO 2 modified NFM). In addition, the CS/DA-TiO 2 -NFM exhibited an increased rejection rate of MgSO 4 (enhanced 40.93%) and water-flux (enhanced 18.10%) compared with the control. These results highlight the potential of the presented approach for designing membranes with effective separation performance and antifouling for drinking water treatment. Graphic abstract
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高影响因子
Marine Drugs
·
2020
·Vol. 18
·期 6
·315
·
IF 4.073
Qinying Yan,Jiaqi Weng,Xieqi Wu,Weiwei Wang,Qingliang Yang,Fangyuan Guo,Danjun Wu,Ying Song,Fan Chen,Gensheng Yang
Chitosan nanoparticles (CS-NPs) are under increasing investigation for the delivery of therapeutic proteins, such as vaccines, interferons, and biologics. A large number of studies have been taken on the characteristics of CS-NPs, and very few of these studies have focused on the microstructure of protein-loaded NPs. In this study, we prepared the CS-NPs by an ionic gelation method, and bovine serum albumin (BSA) was used as a model protein. Dynamic high pressure microfluidization (DHPM) was utilized to post-treat the nanoparticles so as to improve the uniformity, repeatability and controllability. The BSA-loaded NPs were then characterized for particle size,Zetapotential, morphology, encapsulation efficiency (EE), loading capacity (LC), and subsequent release kinetics. To improve the long-term stability of NPs, trehalose, glucose, sucrose, and mannitol were selected respectively to investigate the performance as a cryoprotectant. Furthermore, trehalose was used to obtain re-dispersible lyophilized NPs that can significantly reduce the dosage of cryoprotectants. Multiple spectroscopic techniques were used to characterize BSA-loaded NPs, in order to explain the release process of the NPs in vitro. The experimental results indicated that CS and Tripolyphosphate pentasodium (TPP) spontaneously formed the basic skeleton of the NPs through electrostatic interactions. BSA was incorporated in the basic skeleton, adsorbed on the surface of the NPs (some of which were inlaid on the NPs), without any change in structure and function. The release profiles of the NPs showed high consistency with the multispectral results.Keywords:characteristics;cryoprotection evaluation;dynamic high pressure microfluidization;chitosan nanoparticles
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PubMed
高影响因子
Journal of Chemistry
·
2022
·
IF 3.241
Anxiang Huang,Wenlian Bai,Shoulu Yang,Zhongwei Wang,Nengying Wu,Yanxiong Zhang,Ning Ji,Dan Li
The purpose of this study was to fabricate a low-cost and eco-friendly adsorbent using bamboo biochar (BB), a kind of charcoal composed of high Brunauer–Emmett–Teller surface area and variety of functional groups, and chitosan as substrates for remediation of Cd(II) in Cd(II) contaminated water and characterized the functional group characteristics, surface morphology, and Cd(II) adsorption effect using the Fourier transform infrared (FT-IR), scanning electron microscope (SEM), and energy-dispersive X-ray spectrometer (EDS). Results showed that chitosan-modified bamboo biochar (CBB) provided more active adsorption sites (such as –NH2, –COOH, –OH, and C=O) on the surface to enhance the Cd(II) removal efficiency in Cd(II) contaminated wastewater. Meanwhile, the optimal pH, contact time, and dose of CBB on the Cd(II) removal efficiency are 7, 120 min, and 600 mg, respectively. In addition, the adsorption isotherm results revealed that the possible adsorption mechanisms might include surface adsorption, electrostatic adsorption, and ion exchanges. Furthermore, the maximum adsorption capacity (Qm) values predicted from the Langmuir model were 37.74 and 93.46 mg/g for BB and CBB, respectively, also indicating a potential application of CBB in practical wastewater. Desorption and regeneration of CBB were attained simultaneously and the results showed that even after five cycles of adsorption-elution, the adsorption and desorption of CBB exhibited a slight decline and still reached at 71.70% and 65.92%. Results from this study would provide a reference to functionalized CBB for Cd(II) adsorption in contaminated water.
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高影响因子
POLYMER SCIENCE SERIES A
·
2021
·Vol. 63
·期 5
·576-584
·
IF 1.206
Cong Ding,Xu Bohao,Zhang Juzhong,Sun Qingqing,Chen Zhihao,Liu Shuiren,Liu Xuying,Chen Jinzhou
Abstract The development of flexible capacitive pressure sensors with high sensitivity and fast response demands the need for thin dielectric films with excellent mechanical flexibility and remarkable dielectric properties. Herein, a graphene/polyurethane (TPU) dielectric was designed by dispersing graphene fillers into TPU elastomer through chitosan (CS) modification. The dispersion of graphene fillers in the TPU matrix can be effectively improved by using CS as mediating agents, thus further elevating the dielectric properties of the composites. The as prepared dielectric films exhibit high permittivity (90), low dielectric loss (0.02) and remarkable flexibility. Afterwards, the flexible dielectric films were employed to construct capacitive sensors by integrating the top electrode, dielectric layer, and bottom electrode into a sandwich structure. Taking advantage of the high permittivity of the dielectrics and the microcapacitors generated between graphene fillers, the corresponding sensors exhibit high sensitivity to loaded pressure ( S = 0.53 kPa –1 for the range 1.6–4.8 kPa) and out-of-plane bending ( S = 0.08 deg –1 for the range 0 ~ 150°). In addition, a 3 × 3 sensor array was successfully fabricated and applied in the real-time monitoring of water drop, sensing subtle touch, and mapping the spatial distribution of pressure. The fabricated sensors demonstrate promising potential in the application of human-machine interfaces and wearable devices.
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高影响因子
PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY
·
2018
·
IF 1.241
Mingcong Shao,Lili Xiu,Haijiang Zhang,Jianying Huang,Xingwen Gong
Chitosan/cellulose-based beads (CCBs) for the affinity purification of histidine-tagged proteins were prepared from chitosan/cellulose dissolved in ionic liquid as a solvent, and their structures were characterized by Fourier transform infrared spectroscopy, transmission electron microscopy, and thermogravimetric analysis. The affinity purification was used to separate hexahistidine-tagged (his-tagged) enhanced green fluorescent protein (EGFP) from Escherichia coli. The results showed that Zn2+–CCB exhibited more specific adsorption capacity toward the target protein compared with Ni2+–CCB and Cu2+–CCB. The maximum adsorption of EGFP was 1.84 mg/g of Zn2+–CCB, with 90% purity under the optimized conditions (ionic strength (1.0 M NaCl), pH (7.2) and imidazole concentration (500 mM)). In addition, a regeneration method for the sorbent was further developed by washing with ethylenediaminetetraacetic acid disodium and then reimmobilizing with metal ions. This technique is an alternative method for the purification of his-tagged proteins, making the process more economical, fast, stable, and large batch.
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DOI
PubMed
高影响因子
Sustainable Materials and Technologies
·
2020
·
IF 4.375
Zeheng Li,Nan Xu,Ying Sha,Jiapeng Ji,Tiefeng Liu,Lijing Yan,Yi He,Junchao Zheng,Min Ling,Yingying Lu,Chengdu Liang
Rechargeable lithium metal batteries are among the most versatile platforms for high energy electrochemical energy storage . Unfortunately, uncontrollable growth of lithium dendrite triggers serious safety hazards, low Coulombic efficiency, and short cycling life, impeding the commercial application of lithium metal anode in the advanced energy storage technology , such as lithium-air and lithium‑sulfur (Li S) batteries. Herein, Chitosan oligosaccharide (CSO), an abundant bioderived material was employed to guide uniform lithium deposition and growth. CSO offers three features simultaneously, polar functional groups (-OH and -NH 2 ), natural porous structure , and abundant sources. CSO with a large number of polar groups has strong interactions with Li ions , which could guide the Li ions to form uniform Li deposition. Moreover, the porous structure of CSO could serve as a Li host to accommodate the huge volume change during Li plating and stripping process. Additionally, CSO is a low-cost, abundant, and nontoxic bioderived material, which is suitable for large-scale production of the CSO-Li anode. The proposed strong interactions of CSO with Li ions were confirmed by density functional theory calculations. As expected, the CSO modified electrode demonstrates an outstanding average Coulombic efficiency of over 98% for 600 cycles at a current density of 2 mA cm −2 . And stable cycling performances were achieved in the CSO-Li/CSO-Li symmetrical cells. Moreover, when paired with the LiFePO 4 cathode, Li 4 Ti 5 O 12 anode, high-mass-loading LiNi 0.5 Co 0.2 Mn 0.3 O 2 cathode, and S cathode, the cells using the CSO-Li anodes show the higher capacities and better cycling stabilities compared with those of the cells using the bare Li anodes.
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高影响因子
JOURNAL OF BIOMATERIALS APPLICATIONS
·
2016
·
IF 1.988
Fang Wang,Siqian Yang,Jian Yuan,Qinwei Gao,Chaobo Huang
In the present study, alginate nanoparticles were firstly prepared for paclitaxel (PTX) delivery with an average size of 200 ± 21 nm. To improve the stability and targeting effect, the chitosan (CS) and folate-chitosan (FA-CS) were introduced to form PTX-loaded CS/ALG NPs and FA-CS/ALG NPs by a new double emulsion cross-linking electrostatic attraction method. The optimization chitosan concentration was 0.5% obtained from the experiment results. The CS/ALG-PTX NPs and FA-CS/ALG-PTX NPs had the average particle size of 306.9 ± 12.9 nm and 283.6 ± 19.2 nm with the zeta potential of 31.1 ± 1.3 mV and −2.98 ± 0.7 mV, and had higher drug loading and entrapment efficiencies than ALG-PTX NPs. The in vitro drug release profile along with release kinetics and mechanism from PTX-loaded NPs were studied under two simulated physiological conditions. Further, the in vitro anti-cancer activity of nanoparticles and the cellular uptake of nanoparticles on HepG2 cells were investigated. The results demonstrated that alginate, CS/ALG and FA-CS/ALG can be used as nanoformulation drug carriers by our new method, and FA-CS/ALG was a promising vehicle for anticancer drug targeted delivery system.
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PubMed
高影响因子
POLYMER SCIENCE SERIES B
·
2021
·Vol. 63
·期 3
·272-279
·
IF 1.049
Liangliang Yang,Liu Fang,Zhao Qun
Abstract The antibacterial properties of chitosan and self-repairing properties of collagen-I play important roles in the medical field. New types of collagen-I/chitosan/methyl vinyl silicone rubber materials have been synthesized by blending and grafting copolymerization. The effects of chitosan contents on mechanical and antibacterial properties of collagen-I/chitosan/methyl vinyl silicone rubber were investigated, while the morphology and molecular structure were observed and analyzed. It was determined that the antibacterial and self-repairing properties of collagen-I/chitosan/methyl vinyl silicone rubber were better than those of methyl vinyl silicone rubber. Additionally, the optimal contents of chitosan and collagen-I were determined to be 5 wt % and 5 mg/mL, respectively.
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高影响因子
SENSORS AND ACTUATORS A-PHYSICAL
·
2019
·
IF 2.739
Pengjia Qi,Tong Zhang,Jieren Shao,Bai Yang,Teng Fei,Rui Wang
A quartz crystal microbalance (QCM) humidity sensor based on graphene quantum dots-chitosan (GQDs-CS) sensitive film has been successfully fabricated in this work. The composite ratio of sensitive material and the coating quality of the sensitive film were optimized. The morphological and chemical properties of GQDs-CS composites were inspected via scanning electron microscopy (SEM), transmission electron microscopy (TEM) and Fourier Transform infrared spectroscopy (FT-IR). The results manifest that prepared QCM sensor exhibits high response sensitivity (a frequency shift of −3291 Hz at 95% RH), short response/recovery time (36 s/3 s), tiny humidity hysteresis (˜1.6% RH), and excellent reproducibility, reversibility and long-term stability. Additionally, the electroacoustic parameters of the QCM sensors were also investigated by means of the impedance analysis method. Based on dynamic and static analysis of the sensor, it is speculated that the introduction of GQDs into CS enhanced the mechanical stiffness of the CS film, which could effectively improve the performance of QCM sensor.
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高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2018
·
IF 6.578
Zhi Xu,Guozhen Liu,Hua Ye,Wanqin Jin,Zhanfeng Cui
Pervaporation dehydration is an energy efficient process for purifying organic solvents , whose application depends on the development of highly permeable and selective membranes. In this work, synthesized two-dimensional Ti 3 C 2 T x MXene nanosheets were incorporated into chitosan (CS) to fabricate a new MXene/CS mixed-matrix membrane used for solvent dehydration via pervaporation process. The morphology, chemical structure and surface hydrophilicity of the membranes were studied by SEM, AFM, IR, XPS and water contact angle measurement. Three kinds of organic solvents , ethanol, ethyl acetate and dimethyl carbonate were used for evaluating the membrane dehydration performance. The results indicated that incorporation of MXene nanosheets did not increase the surface sorption , whereas the assembled MXene laminates with interlayer channels greatly enhanced the permeation of water molecular through the membrane. Thus, flux and separation factor of CS membrane were simultaneously improved by introducing the MXene nanosheets . Specifically, the optimized 3 wt% MXene/CS MMM exhibited total flux of ~ 1.4–1.5 kg/(m 2 h) and separation factor of 1421, 4898 and 906 for dehydration of ethanol, ethyl acetate and dimethyl carbonate at 50 °C, respectively.
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高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2021
·Vol. 139
·期 5
·51593
·
IF 3.125
Xinyu Wang,Chenyu Zhou,Shengsong Dai,Junjie Wang,Zhiquan Pan,Hong Zhou
A bio-based flame retardant (PDE) was synthesized through a facile one-pot reaction of 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide (DOPO) with protocatechualdehyde and ethanol. PDE was fully characterized by fourier transform infrared spectroscopy (FTIR), 1 H NMR, 31 P NMR and ESI-MS. Epoxy resin (EP) with 9 wt% PDE (EP/9%PDE) passed UL94 V-0 rating and possessed the limited oxygen index (LOI) value of 33.2%, the curved EP thermosets kept transparent. When chitosan (CS) was used to replace one-third of PDE in EP/9% PDE, the modified EP also passed UL94 V-0 rating with the LOI value of 32.3%, the curved thermosets kept transparent and owned better absorption effect toward ultraviolet light. Cone calorimeter test and TG-FTIR analysis were performed on the EP samples, the chars after burning were characterized by scanning electron microscope (SEM), energy-dispersive X-Ray spectroscopy (EDX), Raman spectrum and FTIR. The results showed that the synergistic effect of PDE-CS on flame retardant was ascribed to the protective effect of denser char layer, the release of some phosphorus containing free radicals and the dilution effect of released nonflammable gases such as H 2 O and CO 2 .
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高影响因子
MOLECULES
·
2018
·Vol. 23
·期 10
·2604
·
IF 3.098
Lijie Wei,Yuan Chen,Wenqiang Tan,Qing Li,Guodong Gu,Fang Dong,Zhanyong Guo
In this study, a series of triple quaternized chitosan derivatives, including 6-O-[(2-hydroxy-3-trimethylammonium)propyl]-2-N-(1-pyridylmethyl-2-ylmethyl)-N,N-dimethyl chitosan chloride (7), 6-O-[(2-hydroxy-3-trimethylammonium)propyl]-2-N-(1-pyridylmethyl-3-yl- methyl)-N,N-dimethyl chitosan chloride (8), and 6-O-[(2-hydroxy-3-trimethylammonium)propyl]- 2-N-(1-pyridylmethyl-4-ylmethyl)-N,N-dimethyl chitosan chloride (9) were successfully designed and synthesized via reacting epoxypropyl trimethylammonium chloride with theN-pyridinium double quaternized chitosan derivatives. Detailed structural characterization was carried out using FT-IR and1H-NMR spectroscopy, and elemental analysis. Besides, the activity of the triple quaternized chitosan derivatives against three common plant pathogenic fungi,Watermelon fusarium,Fusarium oxysporum, andPhomopsis asparagi, was investigated in vitro. The results indicated that the triple quaternized chitosan derivatives had enhanced antifungal activity when compared to double quaternized chitosan derivatives and chitosan, especially at 1.0 mg/mL, which confirmed the theory that the higher density of positive charge contributed to the antifungal activity. Moreover,8with an almost 99% inhibitory index showed the better antifungal activity againstWatermelon fusarium. Moreover, the cytotoxicity of the products was also evaluated in vitro on 3T3-L1 cells and all the triple quaternized chitosan derivatives exhibited low cytotoxicity. These results suggested that triple quaternized chitosan derivatives may be used as good antifungal biomaterials.
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高影响因子
危险品化学品经营许可证（带存储）