ACS Chemical Neuroscience
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2019
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IF 3.861
Lu Kou,Yuemei Duan,Pengcheng Wang,Yaru Fu,Nerek Darabedian,Yonghui He,Dianlu Jiang,Dinglong Chen,Juan Xiang,Guokun Liu,Feimeng Zhou
The aberrant autoxidation of norepinephrine (NE) in the presence of oxygen, which is accelerated by Fe(III), has been linked to the pathogenesis of the Parkinson’s disease (PD). Adenosine triphosphate (ATP), as a neurotransmitter whose release can be stimulated by tissue damage and oxidative stress, is co-stored and often co-released with NE in presynaptic terminals. We have shown previously that ATP inhibits the iron-catalyzed dopamine oxidation, thereby decreasing the production of certain neurotoxins such as 6-hydroxydopamine. Whether ATP plays a similar role in Fe(III)-catalyzed NE oxidation and how it maintains the NE stability have not been investigated. Here, we studied the coordination in a ternary complex among NE, Fe(III), and ATP, and found that Fe(III) is coordinated as a octahedral center by NE and ATP. Voltammetry and mass spectrometry were employed to examine this ternary complex’s modulation of the NE autoxidation. NE–Fe(III)–ATP plays a protective role to modulate the autoxidation and Fe(III)-catalyzed oxidation of NE. The ternary complex can be detected in the substantia nigra (SN), locus coeruleus (LC), and striatum regions of C57BL/6 wild-type mice. In contrast, the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced PD mouse brains displayed a significant decrease of the ternary complex in the SN region and an increase in the LC and striatum areas. We posit that the ternary complex is produced by noradrenergic neurons as a protective regulator against neuronal damage and oxidative stress, contributing to the lower vulnerability of LC neurons with respect to that of SN neurons.
研究领域:
神经科学
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医学
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生物化学
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ACS Omega
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2019
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IF 2.584
Jinjuan Xue,Zhengrong Zhu,Yuqing Zong,Chengjuan Huang,Mingxin Wang
This study investigates the degradation of dimethyl phthalate (DMP) with hydrogen peroxide and ferrate (Fe(VI)) under various reaction conditions. The results showed that the optimum conditions for dimethyl phthalate removal from water were as follows: (a) pH 7.0 and (b) the original molar ratio of [Fe(VI)]/[H2O2]/[DMP] equal to 10:2:1. Under the optimum conditions, the degradation rate of DMP can reach 89.7% in 360 min. Furthermore, 2,5-dihydroxybenzaldehyde, isophthalic acid, 2-ethylhexanol, oxalic acid, 2,6-dihydroxybenzoic acid, 2,6-dihydroxybenzaldehyde, 2,5-dihydroxybenzoic acid, and monomethyl phthalate were identified as the degradation intermediates, and degradation pathways were proposed.
研究领域:
环境化学
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水处理
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高级氧化过程
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Journal of Materials Chemistry C
·
2023
·Vol. 11
·期 35
·12037-12047
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IF 6.4
Ruifeng Wu,Haibing Li,Yafei Liu,Aimin Chang,Bo Zhang
It is found that the linearization of the resistance–temperature curve for CaCu3Ti4O12 can be achieved by changing the energy band structure induced by Fe3+, but at the cost of decreasing temperature sensitivity. Here, a novel strategy is proposed to improve the thermal and dielectric properties of CaCu3Ti4O12 ceramics by (La,Fe)-co-doping. This can both linearize the resistance–temperature relationship by adjusting the energy band structure of the grains due to the Fe3+ doping and improve the temperature sensitivity by increasing the grain boundary potential barrier resulting from La3+ doping. The dielectric constant increases upon decreasing the grain boundary potential barrier and increasing the carrier concentration. Therefore, the dielectric constant and temperature sensitivity can be regulated by adjusting the characteristics of grains and grain boundary. This work bridges the relationship between thermal sensitivity and dielectric properties, and opens up a door for the development of a multifunctional coupler CaCu3Ti4O12 device.
研究领域:
材料科学
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电子工程
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JOURNAL OF ALLOYS AND COMPOUNDS
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2022
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IF 6.371
Yan Huang,Bowen Zang,Chang Zhang,Mingliang Xiang,Peng Xiao,Juntao Huo,Meng Gao,Rie Umetsu,Min Ji,Bingnan Yao,Yan Zhang,Yaocen Wang,Junqiang Wang
Coating soft magnetic powders by an insulation layer is an effective way to improve the high-frequency performance of soft magnetic powder cores. The quality of insulation coating is highly dependent of the coating materials and the coating method. In the present work, a commercial amorphous powder (Fe 73 Si 11 B 11 C 3 Cr 2 ) was primarily coated by a PDA/PEI layer by a co-deposition method in alkaline solution. A thick PDA/PEI layer with good homogeneity was co-deposited on the surface of amorphous soft magnetic powders. The high frequency core loss of magnetic powder cores was reduced by up to ~ 44 % at the magnetic induction of 0.1 T and the frequency of 100 kHz by primarily coating the amorphous powders by PDA/PEI. Microscopic images showed that the PDA/PEI coating layer on the amorphous powders does not peel off while being compressed. These results indicates that PDA/PEI insulation coating is a coating method which can effectively improve the comprehensive magnetic properties of magnetic powder cores.
研究领域:
材料科学
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磁学
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DOI
高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2020
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IF 5.162
Jie Chen,Xicheng Wang,Hua Ye,Zhenyan Yu,Longbao Feng,Jing Zhou,Yajin Che
As one of the most commonly used materials in liver tissue engineering, hydrogel has received much attention in recent years. In this work, we prepared a gelatin methacrylate (GelMA)/oxidized hyaluronic acid (OHA)/galactosylated chitosan (Gal-CS)/Fe (III)@ [email protected] 200 (TA200) hydrogel loaded with insulin-like growth factor 2 (IGF-2) for regeneration of damaged hepatocytes. Fe (III)@TA microspheres served as carrier to achieve sustained release of IGF-2 to promote hepatocytes regeneration. Galactose ligands could bind to the asialoglycoprotein receptor (ASGPR) on the surface of hepatocytes. Galactosylated chitosan could significantly increase the specific function of hepatocytes. The hydrogel we prepared had a storage modulus of 1100 Pa and was suitable for migration of hepatocytes. The release ratio of IGF-2 could reach up to 90% within 14 days. For carbon tetrachloride (CCl 4 ) induced human hepatic stellate cell line LX2 damage, GelMA/OHA/Gal-CS/TA200 hydrogel could significantly improve the survival of LX2 cells. The expression of HNF-4α and transferrin was detected in LX2 cells treated with hydrogel, indicating that the specific function of the liver was also restored. In summary, the GelMA/OHA/Gal-CS/TA200 hydrogels could be used as new tissue engineering scaffolds for the construction of artificial livers.
研究领域:
组织工程
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肝脏再生
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生物材料
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细胞生物学
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DOI
PubMed
高影响因子
MOLECULES
·
2025
·Vol. 31
·期 1
·
IF 4.6
Mingyu Liu,Bowen Pei,Hongyu Ba,Wei Ni,Huaheng Zhao,Shuang Chen,Jiamin Zhao,Jinsheng Zhao
The oxygen evolution reaction (OER) in water splitting involves complex multi-electron–proton transfer processes and represents the rate-determining step limiting overall electrolysis efficiency. Developing non-noble-metal catalysts with high activity and stability is therefore essential. Herein, a heterogeneous synthesis strategy was employed to in situ construct an iron-rich layered sulfate precursor (Fe0.42Co0.58-SO4/NF) on nickel foam, which underwent deep self-reconstruction in alkaline electrolyte to form nanoflower-like Fe0.42Co0.58OOH/NF. The optimized catalyst maintained its iron-rich composition and hierarchical structure, delivering outstanding OER performance with an overpotential of 220 mV at 10 mA·cm−2, a Tafel slope of 31.9 mV·dec−1, and stability exceeding 12 h at 600 mA·cm−2. Synchrotron analyses revealed dynamic transitions between mono-μ-O and di-μ-O Fe–M (M = Fe, Co) oxygen bridges during reconstruction, which enhanced both structural robustness and active-site density. The Fe-rich environment promoted the formation of Fe3+–O–Fe3+units that synergized with Co4+species to activate the lattice oxygen mechanism (LOM), thereby accelerating OER kinetics. This work elucidates the key role of oxygen-bridge geometry in optimizing catalytic activity and durability, providing valuable insights into the rational design of Fe–Co-based non-noble-metal catalysts with high iron content for efficient water oxidation.
研究领域:
电催化
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材料科学
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能量转换
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水分解
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无机化学
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DOI
PubMed
高影响因子
Molecular Catalysis
·
2026
·
IF 4.3
Minghao Geng,Jiahao Li,Zhengze Li,Meng Sui,Fashe Li,Hua Wang,Zhiyu Hua
Fe-modulated Cu-ZnO CeO 2 catalysts were synthesized via sol-gel method. • Moderate Fe doping suppressed CuO growth and improved Cu dispersion. • Fe tuned the interface and oxygen defects to balance reducibility. • Fe10-CZCe achieved 14.5% CO 2 conversion with high methanol selectivity. • The promotion by Fe stems from interfacial regulation, not new phases. Copper-based catalysts have been widely applied in methanol synthesis from CO 2 hydrogenation. Yet efficient operation at an industrially relevant level remains challenging. The use of CO 2 as a carbon source is still limited by difficult molecular activation and by imperfect interfacial matching. Here, a series of Fe-doped Cu-ZnO CeO 2 catalysts was prepared by a sol-gel route. The influence of Fe content on phase structure, surface electronic environment, reduction behaviour, CO 2 adsorption characteristics and catalytic performance was examined systematically. Fe incorporation did not change the fundamental phase composition of CuO and CeO 2 . It did, however, strongly affect Cu dispersion, the near-surface defect environment of CeO 2 , and the electronic structure of the interface. Moderate Fe addition suppressed CuO crystallite growth, improved Cu dispersion, and produced a more concentrated reduction profile with a more suitable distribution of CO 2 adsorption strength. Excess Fe enhanced defect-related signals and high-temperature adsorption, but also increased interfacial perturbation, which was unfavourable for the further conversion of intermediates. At 3 MPa and 260 °C, Fe10-CZCe showed the best overall performance, giving a CO 2 conversion of 14.5% together with high methanol selectivity and the highest methanol space-time yield. The beneficial role of Fe is therefore linked to reconstruction of the Cu-ZnO CeO 2 interface, which promotes a more effective balance between CO 2 adsorption, activation and hydrogenation. These findings provide a useful perspective for compositional tuning and interface design in Cu-based catalysts. Download: Download high-res image (231KB) Download: Download full-size image
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SEPARATION AND PURIFICATION TECHNOLOGY
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2026
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IF 9.1
Jialu Li,Junhao Lin,Zhongyue Sun,Jiawei Liu,Zhilin Zhang,Huiping Deng
A visible-light-assisted peroxymonosulfate (PMS) activation system based on Fe-doped CeO 2 was developed for the efficient degradation of ofloxacin (OFX) in aqueous environments. Fe incorporation effectively regulated the electronic structure of CeO 2 , leading to enhanced visible-light utilization, promoted charge separation, and accelerated interfacial electron transfer, thereby facilitating PMS activation. The optimized 10% Fe-CeO 2 catalyst exhibited remarkably enhanced catalytic activity, achieving nearly complete OFX degradation within 10 min with an apparent rate constant of 0.3606 min −1 , which was substantially higher than that of pristine CeO 2 and the corresponding control systems. Comprehensive characterizations revealed that Fe incorporation optimized the local electronic environment of CeO 2 , thereby facilitating charge migration and PMS activation. Reactive species quenching experiments combined with electron paramagnetic resonance analyses confirmed that multiple reactive oxygen species, including superoxide radicals (O 2 •- ), sulfate radical (SO 4 •- ), hydroxyl radical ( • OH), and singlet oxygen ( 1 O 2 ), participated synergistically in the degradation process. Density functional theory calculations further revealed that Fe incorporation optimized the electronic distribution of CeO 2 and strengthened the adsorption and electron transfer of PMS and O 2 on the catalyst surface, thereby promoting the generation of oxidative species. This work provides mechanistic insight into Fe-mediated electronic structure modulation for efficient PMS activation and offers a feasible strategy for the rational design of ceria-based photocatalysts for environmental remediation.
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Surfaces and Interfaces
·
2026
·
IF 6
Qiubai Jiang,Tianle Tan,Hui Deng,Jiang Wan,Long Wang,Min Li,Yang Wang,Guangxu Liu
Solar-driven interfacial evaporation (SDIE) is a low-energy and environmentally friendly technology for clean-water production. However, when applied to complex waters, volatile organic compounds (VOCs) can readily enter the condensate. In this study, a sequential strategy involving carbonization followed by composite fabrication was used to construct a CuO@Fe 2 O 3 @CC-SA (CFCC-SA) bimetallic oxide aerogel evaporator with both mechanical stability and flexibility for efficient water evaporation and VOC degradation. Synergistic interactions between Fe and Cu enhanced both the photothermal conversion efficiency and Fenton-like catalytic activity of the material. Meanwhile, the porous aerogel network provided excellent hydrophilicity and rapid water transport, thereby promoting efficient evaporation. Under 1.0 kW m –2 irradiation, the CFCC-SA evaporator exhibited an evaporation rate of 2.06 kg·m –2 ·h –1 , corresponding to an approximately 20% increase relative to the monometallic CuO@CC-SA evaporator. For phenol, CFCC-SA achieved removal efficiencies of 98.4% in the condensate and 63.8% in the raffinate. Furthermore, CFCC-SA maintained high phenol removal performance over a broad pH range and under highly saline conditions (20 wt% NaCl). Overall, by integrating efficient water transport with synergistic bimetallic catalysis, the CFCC-SA evaporator offers a promising strategy for designing SDIE systems that simultaneously enable high-rate water evaporation and VOC removal. Download: Download high-res image (272KB) Download: Download full-size image
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JOURNAL OF THE EUROPEAN CERAMIC SOCIETY
·
2026
·Vol. 46
·期 16
·118645
·
IF 6.3
Yuzhe Xie,Jie Zhang,Yuting Liu,Xing Luo,Zixiang Pei,Baohua Cao,Konrad Świerczek,Yang Zhang,Wanbing Guan
To mitigate interconnect corrosion in seawater-fed solid oxide electrolysis cells (SOECs), Mn 1.5 Co 1.5 O 4 spinel coatings were deposited on Fe-22Cr stainless steel. At 750 °C, the coated interconnects exhibited an area-specific resistance (ASR) of 31.8 mΩ cm 2 after 4835 h of oxidation in air, with a parabolic rate constant of 3.0 × 10 −5 mg 2 cm −4 h −1 . Following exposure to seawater vapor for 500 h, the ASR reached 3.36 mΩ cm 2 , with a predicted value of 9.80 mΩ cm 2 at 5000 h. These findings underscore the coating’s improved oxidation resistance under dual-atmosphere conditions. Furthermore, a three-cells stack demonstrated high stability with a low degradation rate of 1.04 × 10 −5 h −1 at 100 mA cm −2 for 100 h. Post-test analysis confirmed a crack-free structure with negligible additional resistance, indicating that the spinel coating satisfies the engineering requirements for durable, direct seawater electrolysis and provides a scalable pathway for green hydrogen production.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2026
·
IF 9.6
Qiyan Sun,Ruixue Zhang,Wen Zhang,Jinsheng Lin,Dianxing Ju,Yongming Chai,Guang-Rui Xu,Lei Wang
Effective modulation of spin state in spinel cobalt oxides by transition metal Fe doping is applied to enhance the chlorine evolution reaction. • Fe-Co 3 O 4 exhibits superior selectivity and stability for the chlorine evolution reaction compared with pure Co 3 O 4 . • The preferential Cl − adsorption on Fe-Co 3 O 4 was confirmed by open-circuit potential measurements and theoretical calculations. The chlorine evolution reaction (CER) is pivotal for advancing the chlor-alkali industry, which is limited by the sluggish kinetics. Transition metal catalysts offer highly tunable electronic structures, where regulating the spin state of metal centers is crucial but challenging for enhancing CER performance. Herein, Fe-doped spinel oxides (Fe-Co 3 O 4 ) were synthesized via a simple sol-gel method. The strategic incorporation of Fe ions introduces geometric confinement, which modulates octahedral distortion at the surface and thereby regulating the spin state of Co centers, ultimately optimizing CER activity and stability. Combined experimental and theoretical analyses reveal that Fe doping triggers a spin-state transition in Co ions from high-spin towards intermediate-spin or low-spin configurations. The enhanced electronic interaction between Co and Fe 3d orbitals in Fe-Co 3 O 4 leads to superior CER selectivity compared to pure Co 3 O 4 , even under unfavorable conditions such as high pH and lower Cl − concentrations. Furthermore, Fe-Co 3 O 4 nanocubes exhibit excellent durability, maintaining stable performance for over 50 h, which is significantly better than that of Co 3 O 4 . Theoretical calculations confirm that octahedral Co and Fe sites in Fe-Co 3 O 4 serve as the active centers for chloride ion release, in contrast to the tetrahedral Co sites in pristine Co 3 O 4 . The spin state modulation of Co not only facilitates chloride ion adsorption but also optimizes the adsorption energetics, elucidating the fundamental mechanism behind the enhanced CER activity. This work highlights the critical role of spin-state regulation at active sites and proposes a chitosan gel-mediated cross-linking strategy for fabricating high-performance CER catalysts. Fe-Co 3 O 4 nanocubes were successfully synthesized via a sol-gel strategy, in which transition metal Fe doping was effectively used to modulate the spin state of Co 3 O 4 in spinel to improve chlorine evolution reaction performance. Download: Download high-res image (135KB) Download: Download full-size image
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LANGMUIR
·
2026
·
IF 4.4
Jiahui Wang,Jingbiao Ge,Huihui Xue,Yang Yang,Sujuan Zhang,Xiuzhen Zheng,Shifu Chen
Photocatalytic water splitting is an effective way to produce H2 and a key research direction in H2 energy development. In this paper, a Fe/FeP/ZnIn2S4 (Fe/FeP/ZIS) composite was prepared by a self-assembly method, with 2D Fe/FeP nanorods attached to the surface of 3D ZnIn2S4 (ZIS) microflowers. When the mass percentage of Fe/FeP loading was 5%, the Fe/FeP/ZIS heterojunction exhibited the best photocatalytic performance (4.56 mmol·g–1·h–1), much higher than that of Fe/FeP and ZIS. The significantly enhanced activity of Fe/FeP/ZIS was ascribed to the close interface contact formed between Fe/FeP and ZIS, which accelerated the separation and transfer of photogenerated charge carriers (PCCs). This study not only offers a reference for the design of novel non-noble cocatalysts but also promotes the improvement in the utilization efficiency of PCCs.
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