COLLOIDS AND SURFACES B-BIOINTERFACES
·
2026
·
IF 5.9
Xuan Shang,Mingyue He,Huiying Jiang,Fangying Jiang,Deping Wang,Jimin Cao,Yan Tan,Jigen Li,Yanlin Feng,Xin Zhou
Cancer remains a global health challenge, calling for integrated strategies that combine precise diagnosis with synergistic treatment. Although glucose oxidase (GOx)-mediated starvation therapy disrupts tumor metabolism by converting glucose into cytotoxic hydrogen peroxide (H 2 O 2 ), its clinical translation is hindered by inefficient delivery and insufficient monotherapy efficacy. To address these issues, we developed a multifunctional nanoplatform by encapsulating GOx within hollow porous superparamagnetic Fe 3 O 4 nanoparticles (Fe 3 O 4 -GOx NPs) to preserve its catalytic activity and enable high loading capacity. This system simultaneously enables magnetic resonance imaging (MRI), photothermal therapy, and enzyme-mediated catalytic intervention. In vitro studies demonstrated strong T 2 -weighted MRI contrast for precise tumor localization, together with near-infrared laser-triggered hyperthermia that enhance the efficacy of GOx-mediated starvation therapy, elevating oxidative stress and promoting apoptosis in 4T1 cells. In 4T1 tumor-bearing mice, a single administration of Fe 3 O 4 -GOx NPs combined with laser irradiation elicited potent tumor suppression through the synergistic effects of intratumoral ROS generation, glucose depletion, and localized photothermal ablation, outperforming either modality alone. Histopathological assessment revealed negligible systemic toxicity and preserved organ integrity. This work presents an integrated theranostic nanoplatform that unites tumor-targeted imaging, enzyme- driven metabolism intervention, and photothermal therapy into a single system, offering a promising strategy for precision cancer management.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Siyu Zhu,Shaojie Shi,Yuqi Yang,Fengjiao Jiang,Xiaoling Gu,Shaodong Jiang,Hongyun Niu,Yaqi Cai
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous and highly persistent in soil. Owing to the potential adverse effects of peroxides to soil ecosystems, oxidant-free advanced oxidation process (AOP) is highly demanded for PAHs remediation. We utilize the composites of phosphatized sludge biochars and core/shell Fe 3 P@Fe (PSL-Fe 3 P/Fe) as catalysts to decompose PAHs in soil. In a wide range of soil moisture, pyrene, benzo[ a ]anthracene, benzo[ a ]pyrene, indeno[1,2,3- cd ]pyrene, and dibenzo[ a , h ]anthracene are efficiently degraded by PSL-Fe 3 P/Fe within 6 h. For the first time, we find that reactive oxygen species resulting from internal micro-electrolysis (IME) of biochars (cathode) and Fe 3 P@Fe (anode) are sufficient for PAHs degradation. Strong adsorption, excellent electrical conductivity, high potential difference between Fe 3 P@Fe anode and biochars cathode, and acid-microenvironment provided by P 2 O 5 component trigger the remarkable reactivity of PSL-Fe 3 P/Fe. The environmental-benign PSL-Fe 3 P/Fe can eliminate the phytotoxicity of high-level of PAHs (200 mg/kg), recover soil microbial diversity, and promote the growth of lettuce Lactuca sativa .
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2026
·
IF 8.3
Chenxi Shang,Zhendong Gao,Boxuan Lu,Huaxia Zhou,Tingting Tang,Tayirjan Taylor Isimjan,Xiulin Yang
Rare-earth metal-based materials have rapidly gained attention as leading candidates for high-performance hydrogen storage, offering a promising direction for the advancement of clean energy technologies. In this study, a novel composite catalyst (Fe–Dy 2 O 3 /CoB) was constructed by introducing the rare-earth metals dysprosium (Dy), which significantly enhanced the catalytic performance of sodium borohydride hydrolysis. The experimental findings revealed that the Fe–Dy 2 O 3 /CoB catalyst demonstrated outstanding hydrogen generation efficiency (5512.4 mL min −1 g −1 ), accompanied by a notably low apparent activation energy (47.81 kJ mol −1 ) at 25 °C. Our results reveal that the incorporation of dysprosium not only optimized the electronic structure of the catalyst but also significantly improved the adsorption and activation of reactants. Additionally, the inclusion of iron imparted magnetic properties to the catalyst, facilitating easy separation and recycling via an external magnetic field. Notably, the hydrogen generated via this catalytic system is sufficient to power fuel cell-driven small vehicles, fully showcasing its practical application capability in on-demand hydrogen supply scenarios. This work highlights the untapped potential of rare-earth elements in tailoring the electronic structure of multi-component catalysts. It establishes a generalizable strategy for designing next-generation hydrogen generation systems based on NaBH 4 hydrolysis.
✓ 已验证
产品关联
DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 2
·121376
·
IF 7.2
Wei Ren,Xiao-Wen Huang,Dongmei Hou,Zhuoyuan Li,Jingenqi Li,Denglong Chen,Yuehong Ma,Chongli Wu,Qian-Qian Tang,Yi Hu,Long-Shuai Zhang,Jian-Ping Zou
Advanced oxidation processes (AOPs) based on peracetic acid (PAA) are widely employed for water purification; however, conventional PAA activation methods often exhibit low efficiency in generating hydroxyl radicals (•OH). Herein, a carbon nitride-supported Fe single atom catalyst (Fe-CN) is employed to activate PAA, achieving efficient degradation of 4-chlorophenol (4-CP). Experimental analyses confirmed that •OH is the predominant reactive species responsible for degradation. Density functional theory (DFT) calculations and in-situ Raman spectroscopy revealed that Fe-CN selectively adsorbs peroxy oxygen atoms from PAA, promoting O-O bond cleavage and •OH formation. The system demonstrated robust stability across a wide pH range, resistance to ionic interference, and high efficiency in natural water matrices. This work provides novel insights into •OH-dominated PAA-based AOPs for sustainable wastewater treatment.
✓ 已验证
产品关联
DOI
高影响因子
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2020
·Vol. 45
·期 41
·21676-21686
·
IF 4.939
Darvaish Khan,Subrata Panda,Zhewen Ma,Wenjiang Ding,Jianxin Zou
The present study focuses on enhancing the yield of Mg 2 FeH 6 and its hydrogen storage performances through a novel high-pressure compression approach. For which, MgH 2 and Fe powders are first mechanically milled in a molar ratio of 2:1 and subsequently compressed to a cylindrical pellet. Due to the compression, the yield of Mg 2 FeH 6 in the compressed 2MgH 2 –Fe pellet (90%) has been increased by 24% as compared to the reference ball-milled powder (66%). The thermodynamic destabilization of Mg 2 FeH 6 in the pelletized sample is observed through measuring the pressure-composition isotherms, resulting in the reduced ab/desorption enthalpy for the pellet sample (−68.34 and 75.61 kJ/mol H 2 , respectively). The hydrogen uptake and release kinetics of Mg 2 FeH 6 is remarkably fast, and it can store/release about 5 wt% H in less than 2.5 min at 400 °C. The faster hydrogen ab/desorption kinetics corresponds to the lower activation energies (36 and 95 kJ/mol H 2 , respectively). The excellent yield of Mg 2 FeH 6 and its improved hydrogen storage properties for the compressed pellet are primarily attributed to the microstructural modifications upon high-pressure compression, and also the obtained results for Mg 2 FeH 6 ternary hydride are linked to the literature data based on theoretical calculations.
✓ 已验证
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2019
·
IF 4.175
Yurong Ren,Xiaofang Lai,Minhao Guo,Ruiqi Wang,Jun Deng,Jikang Jian
Three layered quaternary sulfides, NaLi M S 2 ( M = Mn, Fe, Co) were synthesized by solid-state reactions. They adopt a trigonal CaAl 2 Si 2 -type structure (S.G. P -3 m 1) with Li and M randomly distributed at the tetrahedral metal site. Magnetic measurements reveal spin-glass ground states for these compounds, in contrast to the long-range antiferromagnetic order in the ternary counterpart NaFe 1.6 S 2 . As evidenced by electrical resistivity and optical measurements , all these three compounds show semiconducting nature, consistent with the results of first-principles calculations. The measured band gaps are 3.4 eV and 1.25 eV for NaLiMnS 2 and NaLiCoS 2 , respectively. Photoelectric measurements on NaLiCoS 2 demonstrate its potential application in photovoltaic devices .
研究领域:
材料科学
·
固体化学
·
凝聚态物理
·
无机化学
·
功能材料
✓ 已验证
DOI
高影响因子
ANALYTICA CHIMICA ACTA
·
2026
·
IF 6
Yicheng Yao,Liudi Ji,Peng Hu,Xiaoming Zhu,Junxing Hao,Kangbing Wu
Background Carbendazim (CBZ), is a benzimidazole fungicide and widely used for controlling fruit and vegetable diseases, which poses significant risks to human health due to its neurotoxicity, endocrine disruption, and reproductive toxicity. Sensitive and rapid monitoring of carbendazim residues in food is essential for ensuring food safety. Among the numerous developed methods, electrochemical sensing stands out due to its simplicity of operation, low cost, and capability for on-site detection. Its key point is to construct a high-performance sensing interface. Nevertheless, these interfaces still face some limitations, such as inadequate conductivity, relatively low sensitivity, and narrow linear range. Results Herein, graphene supported iron nanoparticles encapsulated nitrogen-doped carbon nanotubes (Fe@N-CNTs) were constructed. The MOF-derived “tube-bridge” CNTs architecture, enhanced by N-doping, ensures high conductivity and optimized electron transfer pathways. Encapsulated iron nanoparticles act as shielded yet accessible redox-active centers, enhancing catalytic specificity. Graphene prevents CNTs stacking, maximizing active site exposure and interfacial charge transfer. This synergistic design significantly boosts the electrochemical active surface area, electron transfer kinetics, and electrocatalytic activity. As a result, a highly sensitive electrochemical sensing platform for CBZ has been successfully constructed. An irreversible two-electron and two-proton process takes place on the surface of Fe@N-CNTs/Graphene/GCE. The composite demonstrated exceptional performance for CBZ detection, achieving a broad linear range (0.001-7.0 μM), and an ultralow detection limit (0.56 nM). Furthermore, the sensor exhibited superior repeatability, stability, and selectivity. Its practical applicability was successfully validated through the accurate quantification of CBZ residues in medicinal herbs and vegetables ( recoveries of 98.58%-101.7%). Significance This work offering a robust solution for monitoring ultra-low concentrations CBZ residues in complex food matrices. This innovative technology provides essential support for combating pesticide misuse while safeguarding public health and preserving ecological integrity related to CBZ contamination.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2026
·
IF 9.7
Xin Li,Ze Lv,Tong Wu,Bolin Ji,Wei Wu,Yi Zhong,Hong Xu,Zhiping Mao,Linping Zhang
Enhancing the photocatalytic CO 2 conversion efficiency of metal-organic frameworks (MOFs) remain a central challenge in advancing carbon capture and utilization (CCU) technologies. Herein, we report a mixed-ligand strategy to construct a hybrid MOF (denoted as CTN ⊂ NM) by incorporating a Co-metalated tetrakis(4-carboxyphenyl)porphyrin (CoTCPPNa 4 , CTN) into an amine-functionalized MIL-101(Fe) framework (NH 2 -MIL-101(Fe), abbreviated as NM; MIL = Materials of Institute Lavoisier, a prototypical series of robust MOFs). The optimized catalyst with a Co/Fe molar ratio of 0.40 achieves a HCOOH production rate of 119.11 μmol g −1 h −1 under visible light in the absence of a sacrificial agent, representing a 4.2-fold increase compared with pristine NM. When a sacrificial electron donor is introduced, the rate further rises to 179.87 μmol g −1 h −1 . The markedly enhanced activity originates from the synergistic integration of CTN and NM: CTN provides strong visible-light absorption and efficient catalytic sites, while NM offers high porosity and strong CO 2 affinity. This cooperation broadens the light-absorption range, suppresses charge-carrier recombination, and accelerates CO 2 -reduction kinetics. In addition, the Co 3+ center in the metalloporphyrin macrocycle functions as an active CO 2 adsorption site, facilitating its activation and selective conversion to HCOOH. Overall, this study presents an effective mixed-ligand hybridization approach for solar-to-chemical energy conversion and provides valuable insights for the rational design of MOF-based photocatalysts toward carbon-neutral fuel production.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
WATER RESEARCH
·
2026
·
IF 12.4
Mengqiang He,Mingzhu Liu,Xiaolei Teng,Shengnan Zhang,Zunyao Wang,Xiaohong Guan,Ruijuan Qu
Phenolic pollutants, frequently detected in aquatic environments as trace-level mixtures, pose significant challenges for water treatment. In this study, we examined the removal of 35 trace phenol mixtures (0.1 μmol/L each) under Fe(VI) oxidation, revealing kinetic differences between single and mixed systems. Fast-reacting phenols with secondary reaction rate constant ( k app ) > 350 M −1 •s −1 experienced accelerated oxidation upon mixing, whereas slow-reacting ones ( k app ≤ 350 M −1 •s −1 ) exhibited decreased rates. The quantitative structure-activity relationship (QSAR) models were constructed to correlate the k app of these phenols with molecular descriptors, showing that higher E HOMO and lower E gap were conductive to increasing the reaction rate in the mixed system, while E LUMO had a minimal effect on the reaction. Employing molecular networking for non-targeted screening, we identified the prevalence of cross-polymerization within the mixed system, yielding various cross-polymer products. Reaction pathway analysis, TOC and COD measurements, and theoretical calculations collectively demonstrated that electrophilic attacks of Fe(VI) trigger electron loss in phenols, generating phenoxy radicals that drive cross-polymerization and accelerate reaction rates of fast-reacting phenols, aligning with QSAR model predictions. These findings can deepen our understanding of Fe(VI) oxidation mechanism on mixed trace phenols, offering valuable insights for the advancement of wastewater treatment technologies.
✓ 已验证
DOI
PubMed
高影响因子
FULLERENES NANOTUBES AND CARBON NANOSTRUCTURES
·
2018
·
IF 1.011
Dong Liu,Yanxiong Liu,Guannan Liu
The influences of carbon nanotubes (CNTs) additions on the flash ignition characteristics of Iron (Fe) and aluminum (Al) nanoparticles (NPs) were presented. CNTs can be used as the additive to these metal nanoparticles for improving the flash ignition and burning processes. Different mass fractions of CNTs additions were considered. The mixture of Al and CNTs could combust in air with obvious giant flame, whereas the mixture of Fe and CNTs combusted under a relative stable condition with slight red light. The temperature distributions were measured using non-contact optical method and showed that Al NPs mixed with CNTs were burning at a higher temperature level than Fe NPs. Although different mass fractions of CNTs cannot significantly change the overall flash ignition phenomenon, CNTs additions influenced the minimum ignition energy (MIE) of mixtures. The appropriate content of CNTs addition can decrease the Fe NPs MIE significantly. However, the Al NPs MIE decreased all along with the increase of CNTs content. The micro- and nano- structures of Fe and Al NPs with CNTs additions before and after ignitions were examined by scanning electron microscope and high-resolution transmission electron microscopy. It was found that the special thermal conductive characteristics of CNTs and the cross-connected features for metal particles with CNTs caused the enhancement of flash ignition.
✓ 已验证
DOI
高影响因子
ELECTROCHIMICA ACTA
·
2026
·
IF 5.8
Junke Cai,Xujing Zhang,Xinmei Li,Jiahao Ma,Lirong Wei,Yutong Chen
Electrodeposition enabled a Fe-coordinated gradient hydrogel electrolyte. • Fe migration regulated the spatial distribution of coordination crosslinks. • Amide-related covalent linkages and Fe–O coordination formed a dual network. • The gradient dual network balanced mechanical stability and ion transport. • The AC//AC device retained 90.67% capacitance after 10,000 cycles. Hydrogel electrolytes for quasi-solid-state carbon-based supercapacitors need to balance structural stability, ion transport, and electrode/electrolyte interfacial compatibility, which often constrain each other. Here, we developed a carboxymethyl chitosan (CMCS)–sodium l -aspartate (AspNa)–Fe gradient dual-network hydrogel electrolyte through an electric-field-induced electrodeposition strategy. In this system, CMCS/AspNa formed a hydrophilic polymer framework; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (EDC·HCl, hereafter abbreviated as EDC) promoted the formation of amide-related covalent linkages, providing stable skeletal support; and Fe–O coordination was introduced through the in situ release of Fe species from a sacrificial Fe anode. During electrodeposition, electric-field-driven migration coupled with concentration diffusion produced a non-uniform Fe distribution, leading to a spatially heterogeneous coordination/covalent dual network within the hydrogel. FTIR, XPS, and SEM/EDS analyses revealed amide-related covalent linkages, Fe–O coordination, and a gradient Fe distribution, supporting the formation of the gradient dual-network structure. Among the samples with different EDC contents, the hydrogel prepared with 2.0% (w/v) EDC showed a suitable balance between compressive stability and ion transport. The AC//AC symmetric supercapacitor assembled with this hydrogel electrolyte delivered a device-level specific capacitance of 22.81 F g⁻¹ at 0.5 A g⁻¹ and retained over 90% of its initial capacitance after 10,000 cycles at 1 A g⁻¹, with a Coulombic efficiency close to 100%. These results highlight the role of the electrodeposition-induced gradient coordination/covalent network in coupling mechanical support, ion transport, and interfacial stability in quasi-solid-state carbon-based supercapacitors. Download: Download high-res image (150KB) Download: Download full-size image
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MEDICINAL CHEMISTRY
·
2026
·
IF 7.3
Yang Liuxin,Cheng Yiyu,Qin Si,Jiang Jun,Zhong Shiyi,Bi Xinyue,Xu Jiali,Wang Kai,Qiu Shuang,Li Xiang
Cellular resilience to therapy often arises from adaptive
mechanisms
that safeguard iron–sulfur (Fe–S) proteins. Here, we
present a rational strategy to overcome such resilience by integrating
two synergistic vulnerabilities, copper toxicity and Fe–S cluster
homeostasis, into a single molecular scaffold. Inspired by a bacterial
sulfur mobilization (SUF) inhibitor, we hybridized its core structure
with a copper-transporting 8-hydroxyquinoline moiety to generate HDQ , HDQ-S , HDQ-Ph , and HDQ-Me . They coordinate copper via hydroxyquinoline and efficiently transport
copper into cancer cells, with HDQ-Me achieving an efficacy
comparable to that of the clinical copper ionophore elesclomol ( ES ). Strikingly, HDQ alone suppresses Fe–S
proteins across multiple functions, including respiration, iron homeostasis,
and DNA replication. HDQ -mediated copper loading triggers
cuproptosis hallmarks, DNA damage, and ATP collapse, generating a
synergistic lethality. This work establishes HDQs as
bifunctional tools that cotarget copper and Fe–S protein homeostasis,
validating a convergent therapeutic strategy against resilient cells.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）