ACS Omega
·
2026
·
IF 4.3
Yutong Feng,Hui Sun,Xinyu Liu,Huiping Wu,Gaoyuan Chen,Afang Gao,Shijie Wang,Jiahui Zhou,Bin Yu
Flexible electrochemical sensors based on noninvasive materials can continuously monitor blood glucose levels in sweat, making them ideal for personal diabetes management intelligent devices. It is necessary to construct sweat glucose electrochemical sensors that have the ability to both adjust to human skin and reliably monitor. We first synthesized nickel/cobalt metal–organic framework material (Ni/Co-MOF) nanosheets via a solvent-thermal approach. Then, an oil-based polyurethane (OPU)/polypropylene spun-bonded nonwoven fabric (PPSF) was obtained by coating the surface of PPSF. Silver/silver chloride (Ag/AgCl) paste and conductive carbon (C) paste were printed layer-by-layer on the surface of the OPU/PPSF by screen printing, followed by the immobilization of Ni–Co/MOF nanosheets on the working area using a Nafion solution to form a Ni/Co-MOF@OPU/PPSF flexible glucose sensor for continuous monitoring of glucose in sweat. This Ni/Co-MOF@OPU/PPSF flexible glucose sensor retained the high electrocatalytic activity of Ni/Co-MOF for glucose oxidation and exhibited high sensitivity (159.9 μA/mM·cm2), low limit of detection (LOD) (2 μM), and a wide linearly glucose-monitoring range (10 μM–1 mM). Compared to other nonenzymatic sensors, our Ni/Co-MOF@OPU/PPSF flexible glucose sensor has better immunity than other substances present in sweat. Meanwhile, the Ni/Co-MOF@PPSF flexible glucose sensor not only monitors the glucose in sweat at different body temperatures but also maintains good mechanical flexibility and stable electrochemical properties under bending conditions. It is suggested that our flexible glucose sensor can be used for continuous monitoring of glucose in human sweat. Overall, our glucose sensor can be used for the continuous monitoring of glucose in human sweat.
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PubMed
高影响因子
Biotechnology for Biofuels and Bioproducts
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2026
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IF 4.6
Xinran Yu,Su Ma,Xiuyun Wu,Lushan Wang
Background: Efficient degradation of cellulose is a key bottleneck in the industrialization of biofuels. While fungi achieve substrate conversion through precise regulation of cellulase systems, the systematic mechanisms underlying efficient degradation (encompassing gene transcription, extracellular protein cooperation, and product metabolism) remain unclear in specific fungi, especially thermophilic fungi critical for industrial production. Results: (1) C. thermophilum did not induce cellulases under cellobiose, while microcrystalline cellulose (MCC) strongly activated degradation. CtClr-2 acts as a core transcription factor, directly driving the co-expression of key genes including LPMOs, CDH, and CBH; its deletion reduces MCC degradation efficiency by 30%. (2) Enzyme secretion may follow a three-stage cascade pattern (CBH1-A → LPMOs/CDH-1 → CBH1/2-B), where the selective secretion and temporal synergy of oxidases and hydrolase increase the reducing sugar yield by 60.6%. (3) The sugar acid metabolic network may enable efficient utilization of degradation products and potentially help maintain extracellular pH. Conclusions: This study reveals the efficient "transcriptional regulation-enzyme secretion adaptation" synergistic mechanism in C. thermophilum. CtClr-2 coordinates key genes, and staged enzyme secretion optimizes synergy, while sugar acid metabolism ensures homeostasis. These insights advance thermophilic cellulolysis understanding and provide targets for engineering industrial strains through synthetic biology (for example, enhancing enzyme yield and optimizing degradation efficiency), aiding cost reduction in biofuel production.
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PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 3
·122907
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IF 7.5
Xiaoyu Ma,Tao Liu,Jiaheng Huang,Jiaqi Zhang,Chengyong Yu,Tianyong Huang
Photocatalytic CO₂ reduction is a promising route for valorizing carbon resources. In liquid-phase systems, TiO 2 suffers from limited CO₂ adsorption, high interfacial charge-transfer resistance, and rapid carrier recombination. These drawbacks hinder simultaneous improvements in efficiency and selectivity. We fabricated a TiO 2 /UiO-66/Cu ternary photocatalyst using a modified-then-loaded strategy. Amino-functionalized TiO 2 was chemically anchored to UiO-66 via N–Zr coordination, forming a robust, low-resistance TiO 2 /MOF interface while preserving the CO₂-enrichment pores of UiO-66. Cu nanoparticles were then introduced as electron traps and catalytic sites to extract photogenerated electrons from the recombination-prone Type-I heterojunction, enabling directional electron utilization. In a solid–liquid system using water as the proton source, the optimal TiO 2 /UiO-66/Cu produced 86.76 μmol·g⁻¹ CO and 9.08 μmol·g⁻¹ CH 4 after 4 h of UV–visible irradiation. The CO production rate was 7.4- and 3.8-fold higher than that of pristine TiO 2 and UiO-66, respectively. Characterization shows that N–Zr coordination reduces charge-transfer resistance, UiO-66 enriches CO₂, and Cu promotes electron capture. Together, these effects mitigate the intrinsically poor charge separation of Type-I heterojunctions and enable efficient CO 2 photoreduction. The results provide design and mechanistic insights for MOF-enabled TiO 2 composite photocatalysts.
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高影响因子
PLoS One
·
2026
·Vol. 21
·期 4
·e0347425
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IF 2.8
Lingyan Chen,Miaomiao Zhu,Xinliang Liu,Qiong Wei
This study aimed to develop a hydrogel-based co-culture system for pancreatic α- and β-cells to mimic native islet composition and achieve bidirectional blood glucose regulation. Monodisperse sodium alginate microsphere encapsulating α-TC6 and β-TC6 cells in a 2:8 ratio were fabricated using a microfluidic electrostatic spray platform. Key processing parameters (voltage, collection distance, flow rate, and alginate concentration) were optimized to precisely control microsphere diameter, yielding highly uniform spheres with excellent monodispersity. The alginate hydrogel exhibited favorable swelling properties and viscoelasticity, providing a supportive 3D microenvironment. In vitro, the microspheres demonstrated high biocompatibility, with cell viability exceeding 95% after 72 hours of co-culture. Encapsulation did not impair cellular function, as evidenced by unhindered insulin and glucagon secretion compared to unencapsulated controls, in streptozotocin-induced diabetic C57BL/6 mice, transplantation of these cell-laden microspheres into the subcutaneous brown fat significantly improved glucose homeostasis. Treated mice showed markedly better glucose tolerance during intraperitoneal glucose tolerance tests and maintained lower fasting blood glucose levels compared to sham-operated and unencapsulated cell transplantation groups. Furthermore, the treatment alleviated diabetes-associated weight loss, with the microsphere group showing a significant weight increase post-transplantation. Histological analysis confirmed the biocompatibility of the implants, with no significant pathological changes in major organs. In conclusion, this sodium alginate microsphere system effectively co-cultures functional islet cells, provides immunoisolation, and restores bidirectional glucose regulation in a diabetic mouse model, offering a promising strategy for pancreatic islet modeling and cell- based diabetes therapy.
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PubMed
高影响因子
JOURNAL OF THE AMERICAN CERAMIC SOCIETY
·
2026
·Vol. 109
·期 4
·e70713
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IF 4.2
Shucheng Liu,Shangchao Chi,Kui Chen,Feng Si,Moke Zhou,Bin Tang
A series of fine-grained Dy/Y co-doped BaTiO 3 -based ceramics were prepared by sintering in a reducing atmosphere to evaluate their potential as dielectric materials for base–metal–electrode multilayer ceramic capacitors (BME-MLCCs). X-ray diffraction, scanning electron microscope, transmission electron microscope, and energy-dispersive spectrometer analyses confirmed the formation of a core–shell structure with grain sizes of ∼200 nm, as well as localized interfacial stress at grain boundaries. Among all compositions, the Y5 sample (moderate Y doping, 1.5 mol%) exhibited a high dielectric constant of 2968, maintained excellent temperature stability within the EIA X7P specification (temperature coefficient of capacitance, TCC ≤ ±10%, temperature range from –55°C to 125°C), and suppressed abnormal grain growth. Reliability tests showed that this composition exhibited the longest lifetime and the highest breakdown field. Impedance spectroscopy and COMSOL simulations further substantiated the role of Y 3 + in suppressing vacancy migration and dispersing local electric fields. This study provides a theoretical reference for miniaturized, high-reliability BME-MLCCs.
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高影响因子
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
·
2026
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IF 16.8
Zuojun Yang,Guokang Chen,Yong Wang,Xuheng Jiang,Qinfeng Zheng,Shun Zheng,Pengtao Xu,Chenji Hu,Yixiao Zhang,Haizu Jin,Xi Liu,Liwei Chen
The high-voltage spinel LiNi 0.5 Mn 1.5 O 4 (LNMO) is a promising cobalt-free cathode with high specific energy, attributed to its high operating voltage (approximately 4.7 V). However, its practical durability is limited by irreversible transition-metal migration, spinel-to-rock-salt phase reconstruction, high-voltage interfacial side reactions, and transition-metal dissolution. Herein, we report a multi-element-doped, cation-disordered spinel LiNi 0.4 Mn 1.4 Fe 0.05 Cr 0.05 Cu 0.05 Nb 0.05 O 4 (HELNMO) synthesized via a solid-state method. Rietveld refinement confirms a single-phase Fd 3̅ m structure with a slightly expanded lattice parameter (8.1857 Å for HELNMO versus 8.1776 Å for LNMO), and energy-dispersive X-ray spectroscopy mapping reveals a homogeneous distribution of the dopant elements. Structural and spectroscopic characterizations consistently confirm enhanced cation disorder in HELNMO, which contributes to favorable electrochemical performance by delivering approximately 130 mAh g −1 at 0.1 C and exhibiting markedly improved cycling stability, retaining 92% of its initial capacity after 1000 cycles at 2 C between 3.5 and 4.9 V. In-situ X-ray diffraction reveals smoother, more continuous lattice evolution of HELNMO than LNMO during (de)lithiation, consistent with a more homogeneous reaction pathway. Post-cycling analyses corroborate suppressed surface rock-salt reconstruction, reduced impedance growth, and alleviated Mn/Ni dissolution. Collectively, multi-element doping coupled with disorder engineering can effectively mitigate transition-metal migration and high-voltage interfacial degradation, providing a practical strategy for durable, high-energy spinel cathodes.
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高影响因子
NEW JOURNAL OF CHEMISTRY
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2026
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IF 2.6
Songlin Chang,Jiaxin Fei,Xiayan Jian,Youchao Song,Yingchen Xu,Yiwei Zhang
Developing simple and efficient synthesis methods for electrocatalysts is the key to advancing the process of electrochemical CO2 reduction reaction (CO2RR). In this study, we employ the simple hydrothermal method and modulate the pH to prepare the CuO-In(OH)3 heterostructure catalyst. It is found that the prepared lamellar CuO-In(OH)3-12 hetero-composite catalyst accelerates the reaction kinetics, provides more active sites, and strengthens the electronic interaction between Cu and In. The obtained catalyst achieves a notable Faradaic efficiency of 40.26% for C2 products at a current density of 18.5 mA cm-2. This work provides a new approach for the development of hetero-catalysts under synthetic regulation methods and different metal combination selections.
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高影响因子
CHEMICAL ENGINEERING SCIENCE
·
2026
·
IF 5.1
Xin Zhang,Zhi-Rong Fu,Jing-Yuan Hao,Yu Han,Hai-Long Liao,Bao-Ju Wang,Yong Luo
The catalytic hydrogenation of nitroaromatic sulfonic acids (NSAs) to synthesize aminoaromatic sulfonic acids (ASAs) is an environmentally promising alternative. However, the deactivation of current catalysts hinders its practical application. In this work, we proposed a strategy of trace sulfur modification to enhance the sulfur-tolerance of the Co@NC catalyst. Characterization revealed that Co@NC-S synthesized with cobalt sulfate has the largest particle size and specific surface area. Using sodium m -nitrobenzenesulfonate (SNS) hydrogenation as a probe reaction, the Co@NC-S catalyst demonstrated superior performance, achieving 99.52% conversion and 98.02% selectivity (100 °C, 3 MPa). Density functional theory (DFT) calculations elucidated that the remarkable sulfur-tolerance of the Co@NC-S catalyst originated from the interaction between the trace sulfur species and the cobalt nanoparticles, thereby weakening the bonding strength of Co with various sulfur-containing compounds. The Co@NC-S catalyst also exhibited excellent stability, magnetic recyclability, and versatility in hydrogenating diverse NSAs, underscoring its significant industrial potential.
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高影响因子
Journal of Energy Chemistry
·
2026
·
IF 15.6
Yimin Jiang,Jixiang Wu,Xichang Liu,Xiangpei Yuan,Chunhui Lu,Yansong Zhou
Electrochemical reduction of carbon monoxide to acetate and ethanol represents a promising strategy for sustainable chemical synthesis. Nevertheless, achieving precise control over product selectivity remains a critical challenge as these compounds originate from complex and closely coupled reaction pathways. In this study, a generalized potential-dependent switch in the dominant pathway for carbon monoxide to C 2 oxygenates on Cu-based electrodes is revealed. At applied potentials above −0.6 V versus the reversible hydrogen electrode, acetate and ethanol are primarily generated via electrode-mediated acetaldehyde disproportionation reaction; at more negative applied potentials, acetate production proceeds predominantly via a ketene-mediated route. Theoretical simulations corroborate the potential-dependent pathway divergence at key intermediates, offering a clear rationale for the observed selectivity trends. These findings establish a comprehensive and unified framework for understanding and guiding product distribution in carbon oxide electroreduction processes. Potential-driven bifurcation controls C 2 oxygenate selectivity in CO electroreduction on copper: low overpotentials favor acetaldehyde disproportionation, while higher potentials promote acetate formation via a ketene intermediate. Download: Download high-res image (171KB) Download: Download full-size image
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高影响因子
APPLIED CATALYSIS A-GENERAL
·
2026
·
IF 4.8
Zhiliang Guo,Huiyu Liu,Bo Jin,Rufang Peng,Qingchun Zhang
A practical strategy was proposed to prepare interlayer Ni-Co DACs. • The Ni-Co DACs achieve a high FE CO of 97% at −0.7 V. • The interlayer Ni-Co DACs possess superior catalytic activity, selectivity, and durability. Developing highly efficient, selective, and stable electrocatalysts for the electrochemical CO 2 reduction reaction (CO 2 RR) is crucial for mitigating energy and environmental challenges. This work presents a practical strategy for synthesizing spatially discrete yet strongly synergistic interlayer dual-metal atom catalysts (DACs) with a Ni-Co configuration through pyrolysis of core-shell zeolite imidazolate frameworks (ZIFs). The resulting CoNC@NiNC catalyst features a core-shell structure where CoNC is encapsulated within NiNC. The strong interaction between the layers of NiNC and CoNC increases the density of active sites, ensures the stability of the structure, facilitates mass or charge transfer, and may produce synergistic interaction between the active sites in core and shell, which can effectively catalyze the conversion of CO 2 to CO. Benefiting from the unique interlayer Ni-Co configuration, the CoNC@NiNC electrocatalyst achieved minimal onset overpotential, high CO Faraday efficiency (FE CO = 97%), and robust operational stability at −0.7 V vs. reversible hydrogen electrode ( vs. RHE). This study demonstrates the promising potential of interlayer DACs for efficient CO 2 RR, more importantly, establishes a viable method for developing interlayer DACs, utilizes the strong interlayer interactions to drive this complex reaction, and inspires further exploration of interlayer DACs in energy conversion and beyond. Download: Download high-res image (152KB) Download: Download full-size image The interlayer dual-metal atom catalysts (DACs) with controlled local coordination environments and three-dimensional spatial structures can efficiently convert CO 2 into high-value chemicals or fuels. Herein, a practical strategy was proposed to prepare interlayer Ni-Co DACs, which have core-shell structure consisted of CoNC encapsulated within NiNC (denoted as CoNC@NiNC), by self-assembly and high-temperature pyrolysis core-shell zeolite imidazolate frameworks (ZIFs) precursor. The practice reveal that the interlayer Ni-Co DACs possess superior catalytic activity, selectivity, and durability, which demonstrates the great potential as highly efficient catalysts for CO 2 RR.
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高影响因子
MATERIALS SCIENCE IN SEMICONDUCTOR PROCESSING
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2026
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IF 5.2
Xiaodong Zhang,Lianrong Zhang,Kaiming Chen,Yitao Wang,Lilong Zhang,Linlin Zhang
Lanthanide-doped perovskite nanocrystals (NCs) have emerged as attractive emitters operating at telecommunication wavelengths. Nevertheless, achieving efficient lanthanide incorporation generally demands high synthesis temperatures (>240 °C), which complicates control over NC size and uniformity. In this work, we revealed that by replacing excess Pb 2+ with lanthanide halides, Ostwald ripening was effectively suppressed, resulting in precise size tuning and enhanced doping. This versatile lanthanide halide–mediated strategy yields highly monodisperse Yb/Er-codoped CsPbCl 3 NCs that exhibit a record photoluminescence quantum yield (21.2%) at 1.54 μm among colloidal perovskite systems. A light-emitting diode (PeLED) was fabricated, showing nearly pure 1.54 μm emission, achieving the peak external quantum efficiency (EQE) of 0.464% under low driving voltage of 2.7 V. In conclusion, the development of 1.54-μm Er-PeLEDs presents new prospects for integrated light sources.
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高影响因子
POWDER TECHNOLOGY
·
2026
·
IF 5.5
Zhaoyu Zhang,Dingsheng Liu
PLGA microspheres were prepared controllably in capillary microreactors. • The microsphere size and size distribution were explored in depth. • PLGA liquid droplet and solid microsphere sizes were compared in detail. Poly(lactic-co-glycolic acid) (PLGA) microspheres are biodegradable materials with good biocompatibility and have demonstrated broad applications in medicine and biology. In this study, PLGA microspheres with controllable sizes and narrow size distributions were prepared using a coaxial microreactor combined with a solvent evaporation method. Based on droplet microfluidics, we systematically investigate the effects of continuous- and dispersed-phase flow rates, polymer solution concentration, and microreactor geometry on microsphere size and size distribution. The size and morphology of the PLGA microspheres were characterized using an inverted microscope coupled with image analysis software. The droplet generation process within the microchannels was also recorded using a high-speed camera mounted on the microscope. This work presents a straightforward and effective method for preparing monodisperse PLGA microspheres, with significant potential for biomedical applications. Fig. PLGA droplet and microsphere preparation. (a) Droplet generation process. (b) Microscopic image of PLGA droplets. (c) Microscopic image of PLGA microspheres. Download: Download high-res image (124KB) Download: Download full-size image
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高影响因子
危险品化学品经营许可证（带存储）