ANALYTICA CHIMICA ACTA
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2018
·
IF 5.123
Maoqiang Chi,Yun Zhu,Liwei Jing,Ce Wang,Xiaofeng Lu
Over the past few years, nanomaterials-based enzymatic mimics have attracted tremendous attention due to their excellent catalytic activity and environmental stability. In this work, ternary MoS 2 -polypyrrole (PPy)-Pd nanotubes have been prepared through a hydrothermal reaction and in situ redox polymerization process between pyrrole monomer and Na 2 PdCl 4 . The prepared MoS 2 -PPy-Pd nanotubes exhibited a higher peroxidase-like catalytic activity than individual MoS 2 , MoS 2 -PPy, PPy-Pd and MoS 2 -Pd nanocomposites due to the synergistic catalytic effect between the three components. The catalytic kinetic of MoS 2 -PPy-Pd nanotubes follows Michaelis-Menten behaviors, exhibiting a good affinity to both 3,3′,5,5′-tetramethylbenzidine (TMB) and H 2 O 2 substrates. On the basis of high peroxidase-like catalytic efficiency of the MoS 2 -PPy-Pd nanotubes, a simple and convenient colorimetric strategy for the rapid and sensitive detection of l -cysteine with a detection limit of 0.08 μM has been developed. In addition, a high selectivity towards the detection of l -cysteine is achieved. This work present an opportunity of the prepared ternary MoS 2 -PPy-Pd nanotubes for promising potential applications in biosensing, environmental monitoring, and medical diagnostics.
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RSC Advances
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2018
·Vol. 8
·期 36
·20087-20094
·
IF 2.936
Tingting Zhu,Ji Xiong,Zhongbo Xue,Yu Su,Fengnan Sun,Ran Chai,Jialiang Xu,Yaqing Feng,Shuxian Meng
Fluorescent probes have been demonstrated to be promising candidates as biomarkers and biological carriers. Our study focuses on the development of a novel amphiphilic fluorescent probe with good photostability, high water solubility, excellent specificity and promising loading capability for tumor diagnosis and treatment. At first, BODIPY dye and O-carboxymethyl chitosan were prepared via a chemical reaction. Then, the prepared BODIPY dye and cRGD were bonded to O-carboxymethyl chitosan successively via an acylation reaction. Finally, we obtained the desired amphiphilic fluorescent probe: BODIPY–O-CMC–cRGD, which was based on the fluorescence resonance energy transfer (FRET) principle for selective visualization of tumors in vitro. Through a series of experiments, we found that this fluorescent probe possessed better fluorescence characteristics and tumor targeting properties. Simultaneously, by self-assembly, the amphiphilic probe encapsulated the other flexible structure of BODIPY2 and the rigid structure of porphyrin, which formed distinct nanoparticles with different particle sizes. Hence, we could observe different phagocytosis processes of the two nanoparticles in the tumor cells via the fluorescence of dyes by confocal laser scanning microscopy. Therefore, the results suggest that the fluorescent probe has advantages in tumor detection, and the constructed tumor-specific nanoparticles show high clinical potential to be utilized not only in visual and precise diagnosis but also in excellent drug delivery for tumor treatment. Henceforth, we will prepare new targeted and visualized pharmaceuticals by replacing BODIPY2 and porphyrin with antineoplastic drugs for future tumor treatment.
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CHEMICAL PAPERS
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2018
·Vol. 72
·期 9
·2203-2214
·
IF 0.963
Sun Qian,Song Xueying,Gao Li,Chen Wei,Li Yamin,Mao Liqun,Yang Jing-He
The series of graphene materials and N-doped graphene materials were successfully synthesized and improved by high-temperature treatment with trace iron oxide. XRD, Raman, FT-IR, TEM and XPS were employed for these catalysts. The catalytic performance of these catalysts was investigated in the selective oxidation of ethylbenzene with tert -butyl hydroperoxide as oxidant. The impacts of temperature, mass of catalysts, reaction time and oxidants on the selective oxidation of ethylbenzene were also investigated. The N-doped graphene materials exhibit greatly remarkable catalytic performance than others. The conversion of ethylbenzene is more than 90% and the selectivity of acetophenone is more than 95% at 353 K. Graphene can be used as catalyst owing to its unique structures and chemical properties. The characterization tests show that the doping of N atoms can create more defects and more active sites in the N-doped graphene materials which could greatly improve the catalytic performance. Furthermore, such cost-effective graphene-based catalysts possess good stability and could be reused at least five times without remarkable loss of the catalytic activity.
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POLYMER BULLETIN
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2018
·Vol. 75
·期 11
·4881-4899
·
IF 1.589
Zhang Mengmeng,Chang Liangliang,Zhao Yuanyuan,Yu Zehao
Montmorillonite/polypyrrole (MMT/PPy) nanocomposites were fabricated by in situ polymerization of pyrrole monomer in the presence of MMT. The structures of the nanocomposites were analyzed by X-ray diffraction, Fourier transform infrared spectra, thermogravimetric analysis and transmission electron spectroscopy. Then, the capability of MMT/PPy nanocomposites on the removal of Eosin Y from aqueous solution was systematically studied. The MMT/PPy nanocomposites showed high adsorption capacity toward Eosin Y and a maximum adsorption capacity of 112.9 mg/g at 35 °C was achieved. The adsorption kinetics demonstrated a rapid Eosin Y uptake by MMT/PPy and the experimental data were well fitted to the pseudo-second-order model. Both the Langmuir and Freundlich models were employed to describe the adsorption isotherms, and the results presented that the equilibrium data obeyed the Langmuir model. Thermodynamic parameters of Δ G ° and Δ H ° verified the spontaneous and endothermic nature of the Eosin Y adsorption onto MMT/PPy. Furthermore, the regeneration experiments revealed that MMT/PPy nanocomposites could be reused after treated with hydrochloric acid solution, showing potential applications in purification of dyeing effluents.
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JOURNAL OF POWER SOURCES
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2018
·
IF 6.945
Gaoming Wu,Han Bao,Zheng Xia,Bin Yang,Lecheng Lei,Zhongjian Li,Chunxian Liu
Anode materials , as the core component of microbial fuel cells (MFCs), have huge impacts on power generation performance and overall cost. Stainless-steel sponge (SS) can be a promising material for MFC anodes, due to its open continuous three-dimensional structure, high conductivity and low cost. However, poor biocompatibility limits its application. In this paper, a polypyrrole/sargassum activated carbon modified SS anode (Ppy/SAC/SS) is developed by electrochemical polymerization of pyrrole on the SS with the SAC as a dopant . The maximum power density achieved with the Ppy/SAC/SS anode is 45.2 W/m 3 , which is increased by 2 orders of magnitude and 2.9 times compared with an unmodified SS anode and a solely Ppy modified SS anode (Ppy/SS), respectively. In addition, the Ppy/SAC layer effectively eliminates electrochemical corrosion of the SS substrate. Electrochemical impedance spectroscopy reveals that Ppy/SAC modification decreases electron transfer resistance between the bacteria and the electrode. Furthermore, in vivo fluorescence imaging indicates that a more uniform biofilm is formed on the Ppy/SAC/SS compared to the unmodified SS and Ppy/SS. Due to the low cost of the materials, easy fabrication process and relatively high performance, our developed Ppy/SAC/SS can be a cost efficient anode material for MFCs in practical applications.
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JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
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2018
·
IF 1.911
Dailian Zhu,Cunqi Qin,Shanshi Ao,Qiuping Su,Xiying Sun,Tengfei Jiang,Kemei Pei,Huagang Ni,Peng Ye
Zinc porphyrin-based porous polymers (PPs-Zn) with different pore sizes were prepared by controlling the reaction condition of click chemistry, and the protein adsorption in PPs-Zn and the catalytic activity of immobilized enzyme were investigated. PPs-Zn-1 with 18 nm and PPS-Zn-2 with 90 nm of pore size were characterized by FTIR, NMR and nitrogen absorption experiments. The amount of adsorbed protein in PPs-Zn-1 was more than that in PPs-Zn-2 for small size proteins, such as lysozyme, lipase and bovine serum albumin (BSA). And for large size proteins including myosin and human fibrinogen (HFg), the amount of adsorbed protein in PPs-Zn-1 was less than that in PPs-Zn-2. The result indicates that the protein adsorption is size-selective in PPs-Zn. Both the protein size and the pore size have a significant effect on the amount of adsorbed protein in the PPs-Zn. Lipase and lysozyme immobilized in PPs-Zn exhibited excellent reuse stability.
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ANALYTICAL CHEMISTRY
·
2018
·
IF 6.042
Guiqiang Pu,Dongxu Zhang,Xiang Mao,Zhen Zhang,Huan Wang,Xingming Ning,Xiaoquan Lu
We provide here, for the first time, a new interfacial electron-induced electrochemiluminescence (IEIECL) system, realizing bionic construction of bioluminescence (BL) by exploiting electrochemiluminescence (ECL) and ITIES (the interface between two immiscible electrolyte solutions). Significantly, the superiority of the IEIECL system is embodied with the solution of the two bottlenecks encountered in the conventional ECL innovation: that are (a) the applications of hydrophobic luminophores in more commonly used aqueous solution are inhibited tremendously due to the poor inherent solubility and the instability of radicals and (b) the analytes, insoluble in water, are hard to be discovered in an aqueous system because of too little content. More productive IEIECL radiation, analogous to BL, originates from the triplet excited state porphyrin in comparison to the homogeneous ECL. The mechanism of IEIECL, as well as the interaction mechanism between IEIECL and charge transfer (comprising electron transfer (ET), ion transfer (IT), and facilitated ion transfer (FIT)) at the ITIES, are explored in detail. Finally, we emphasize the actual application potential of the IEIECL system with the detection of cytochrome c (Cyt c); it is a key biomolecule in the electron transport chain in the process of biological oxidation and is also an intermediate species in apoptosis. Potentially, the IEIECL system permits ones to explore the lifetime and diffusion path of free radicals, as well as imparting a possibility for the construction of a bionic sensor.
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Journal of Materials Chemistry B
·
2018
·Vol. 6
·期 19
·3128-3135
·
IF 4.776
Wenhao Zhou,Ling Lu,Dafu Chen,Zhengao Wang,Jinxia Zhai,Renxian Wang,Guoxing Tan,Jianping Mao,Peng Yu,Chengyun Ning
Conductive polymers (CPs) are frequently used as neural and osteogenic implants for signal recording and electrical stimulation due to their electroactive and good biocompatibility. However, these implants often fail due to bacterial infection. In this research, a novel nano-functionalized polypyrrole (PPy) with high surface potential was electrochemically developed to improve the antibacterial properties of CPs. Sulfosalicylic acid (SSA)—a biomolecule with abundant negatively charged functional groups—was introduced to not only successfully assist in the electrical assembly of Py micelles into a bacterial extracellular matrix mimetic nanostructure, but also to modulate the surface electrical properties of PPy. Scanning Kelvin probe microscopy (SKPM) results confirm the increased positive charges on SSA-assisted PPy (PPy/SSA nanorod and irregular PPy/SSA film) relative to the irregular PPy/Cl film. Plate colony-counting experiments confirm that SSA-assisted PPy has excellent antibacterial properties relative to the irregular PPy/Cl film. The higher antibacterial rate for PPy/SSA nanorods suggests a synergistic effect via the nanorod structure and the high surface potential induced by dopants. Cytotoxicity testing demonstrates that PPy/SSA samples were nontoxic to the cells. Our work provides an effective way to develop antibacterial CPs.
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Journal of Materials Chemistry A
·
2018
·Vol. 6
·期 21
·9874-9881
·
IF 9.931
Yuchao Wang,Canzhu Wang,Xiangju Song,Minghua Huang,Suresh Kumar Megarajan,Saleem Farooq Shaukat,Heqing Jiang
Solar-driven evaporation based on photothermal membrane has been proved to be promising in the field of fresh water generation, and it is considered as an emerging strategy both in laboratory and in industrial scales. However, further research efforts have to be made on light harvesting and thermal management to improve water evaporation. In this study, an extensive research was carried out to develop a bio-inspired 3D photothermal cone for high-efficiency solar-driven evaporation with minimum light reflection and heat loss to bulk water. The artificial photothermal cone with a polypyrrole (PPy) coating layer was facilely fabricated via chemical vapor deposition polymerization (CVDP). The present 3D cone with a rationally designed conical structure exhibited satisfactory absorbance around 99.2% in the entire solar spectrum, which is comparable with the performances of super-black materials. Additionally, the heat loss has been minimized by elevating the photothermal cone to narrow the contact area between water and the PPy-based cone with good wettability, thus achieving a highly efficient interface heating. The solar conversion efficiency up to 93.8% for evaporation was achieved for the photothermal cone under one sun illumination, which is about 1.7 times as high as the result obtained for a plane film. Based on our results, controlling the 3D morphology can be considered as an important strategy for designing a novel high-efficiency photothermal membrane and also, it provides new opportunities in practical application.
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ACS Applied Materials & Interfaces
·
2018
·
IF 8.097
Jiani Huang,Ning Li,Chunmei Zhang,Zhaowei Meng
Metal–organic frameworks (MOFs) have been applied in chemotherapeutic drug loading for cancer treatment, but challenging for cases with large and malignant lesions. To overcome these difficulties, combinational therapies of chemotherapy and photothermal therapy (PTT) with potentially high selectivity and slight aggressiveness have drawn tremendous attention to treat various tumors. However, current MOF-based nanohybrids with photothermal agents involve tedious synthesis processes and heterogeneous structures. Herein, we employ MIL-53 as a microreactor to grow polypyrrole (PPy) nanoparticles in situ for the fabrication of PPy@MIL-53 nanocomposites. Fe3+ in MIL-53, as an intrinsic oxidizing agent, can oxidize the pyrrole monomer to generate PPy nanoparticles. The prepared PPy@MIL-53 nanocomposites integrate the intrinsic advantages of MOFs with high drug loading ability and magnetic resonance imaging (MRI) capacity, and PPy nanoparticles with outstanding PTT ability and excellent biocompatibility. The versatile PPy@MIL-53 nanocomposites with multiple functions displayed in vitro and in vivo synergism of photothermal–chemotherapy for cancer, potentially MRI-guided. The proposed MOF microreactor-based synthesis strategy shows a promising prospect in the fabrication of diverse multifunctional nanohybrids for tumor theranostics in vivo.
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JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
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2018
·
IF 3.609
Zhimin Zou,Chunhai Jiang
A composite anode material consisting of a stable inner core of mesocarbon microbeads and a porous nitrogen-doped amorphous carbon shell active for lithium storage is prepared. The thin birnessite MnO 2 nanosheets hydrothermally deposited on mesocarbon microbeads are in situ replaced by polypyrrole , which is then transformed to nitrogen-doped amorphous carbon layer by calcination in nitrogen atmosphere. The surface modified mesocarbon microbeads exhibit average discharge capacities of 444 and 103 mA h g −1 at the current densities of 0.1 and 3 A g −1 , respectively, obvious higher than the corresponding values of the bare sample, 371 and 60 mA h g −1 . Moreover, the composite anode maintains a discharge capacity of 306 mA h g −1 after 500 cycles at 1 A g −1 , suggesting an excellent cycle stability. It is believed that the nitrogen-doped amorphous carbon layer has provided additional lithium storage capacity and stabilized the structure integrity of mesocarbon microbeads. This work demonstrates that the capacity and rate performance of commercial graphitic carbons can be much improved by simply introducing a nitrogen-doped carbon coating layer active for Li storage, making them attractive for high power Li-ion batteries.
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JOURNAL OF THE ELECTROCHEMICAL SOCIETY
·
2018
·Vol. 165
·期 13
·H872
·
IF 3.662
Meiling Wang,Mingzhu Cui,Laijin Zhong,Lei Qin,Xuguang Liu
Here, we fabricate an ultrasensitive acetaminophen (AC) sensor by using networked nanocarbons (NWNC) derived from hierarchical porous polypyrrole (PPy) hydrogel precursor. Benefiting from the interconnected porous framework and high electron conductivity of this N, P co-doped NWNC, the as-constructed sensor shows record-high sensitivity (102.05 μA μM−1 cm−2) and ultra-low detection limit (3.0 nM), which represents a performance progress in AC sensing. Furthermore, the sensor displays excellent selectivity, reproducibility and stability, exhibiting a great perspective in ultrasensitive monitoring of AC in clinical application.
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