CHEMICAL ENGINEERING SCIENCE
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2024
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IF 4.1
Haoran Ma,Ping Li,Ailing Huang,Wei Zhao,Xuelan Zhang
Sulfonation of 1-tetradecene with liquid-phase sulfur trioxide generates simultaneously the alkene sulfonic acid and alkene sulfonate. The kinetics study is contributed to a deeper understanding of the sulfonation reaction and better controlling the process. The continuous microfluidic system was established to determine the kinetic parameters of 1-tetradecene sulfonation. A comprehensive kinetic model was developed, and the kinetic parameters were obtained. The activation energy is 14.7 ± 0.8 kJ mol −1 , with a pre-exponential factor of 118.4 ± 1.4. The reaction order for 1-tetradecene is second-order, and for sulfur trioxide, the reaction order is 0.3. By discretizing the reactor into microelements and conducting mass balance on each differential element method, integrating the obtained reaction kinetics model, calculating the required reaction time, and comparing it with experimental data within a reasonable range of error, the correctness of the derived reaction kinetics model has been verified.
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高影响因子
BIOCHEMICAL ENGINEERING JOURNAL
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2024
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IF 3.7
Zhimei Zhang,Chao Zhao,Tianming Wu,Yanfeng Xu,Lu Wang,Yusheng Niu
The accumulation of glyphosate during its application in agriculture and its toxicity seriously threaten ecosystems and human health. Currently, glyphosate residual contamination is mainly accomplished through bioremediation techniques based on enhanced microbial degradation activity. However, there are drawbacks, such as poor environmental adaptability of strains and low degradation efficiency. Therefore, in this study, an efficient glyphosate-degrading strain, Pseudomonas alcaligenes Z1–1, was isolated from herbicide-contaminated environments and was capable of completely degrading glyphosate at a concentration of 200 mg/L within 7 days. Kinetics analysis showed that glyphosate degradation was concentration-dependent, with a maximum tolerant concentration of 800 mg/L. Mass spectrometric analysis indicated that AminoMethylPhosphonic acid (AMPA) was the predominant intermediate produced in the degradation pathway of glyphosate, revealing that glyphosate destruction began with breaking the C-N bond. Whole genome sequencing identified the key genes potentially involved in glyphosate degradation, including the thiO , glpA , aroA , soxB , and argA genes. Furthermore, in contrast to the majority of the metabolic pathways previously reported for glyphosate degradation via glyphosate oxidoreductase , the breaking of the C-N bond was primarily catalyzed by glycine oxidase . Overall, this research provides novel insights into the mechanisms of glyphosate degradation, offering valuable degradation enzyme resources for future applications.
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INORGANIC CHEMISTRY COMMUNICATIONS
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2024
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IF 4.4
Yumin Liang,Chenhui Liu,Zhiyu Ma,Jiyun Gao,Yanxin Wu
HKSUT-1 is often used as an adsorbent because of its excellent adsorption properties. In this study, Ag + was impregnated into the HKSUT-1 precursor solution using the impregnation method, with sodium borohydride (NaBH 4 ) serving as the reducing agent. This was done to examine the removal efficiency of NR dye. The Ag-HKSUT-1 composites were prepared by varying the additions of AgNO 3 and NaBH 4 . The morphology and structure of the Ag-HKSUT-1 composites were characterized by TG, FT-IR, BET and TEM. The adsorption performance of AH1 for neutral red dye in wastewater was investigated. The adsorption process was described by the Langmuir model and the pseudo-second-order kinetic model. The adsorption capacity of AH1 for NR dye at 298 K was calculated to be 64.59 mg/g, indicating that Ag-HKUST-1 effectively adsorbed NR dye. The adsorption process is driven by a chemisorption mechanism, where intermolecular forces between Ag-HKUST-1 and NR, electrostatic interactions, and π-π conjugation between benzene rings play key roles. The results enhance our understanding of the surface interactions between Ag-HKUST-1 and NR dyes and broaden the application of HKUST-1 as an adsorbent for pollutant removal in water.
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高影响因子
SOLID STATE SCIENCES
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2025
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IF 3.3
Tingting Yan,Han Li,Dongyang Xi,Linan Liu,Dinghan Jin,Lei Sun
We synthesized the energetic molecular perovskite DAI-1 (C 48 H 112 I 24 N 16 Na 8 O 96 ) and investigated its behavior under high pressure using high-pressure Raman spectroscopy. DAI-1 exhibits an ABX 3 cubic perovskite structure, with significant changes in its Raman spectrum occurring between 4.3 and 7.1 GPa, signaling a phase transition. Releasing the pressure after applying it up to 12.3 GPa showed that the Raman spectrum did not return to its original state, indicating an irreversible phase transition. Furthermore, we conducted simulations to analyze the trend of changes in the crystal structure under pressure. This study serves as a reference for in-depth research on the high-pressure behavior of DAI-1 and other related substances.
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CHEMICAL ENGINEERING JOURNAL
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2024
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IF 13.3
Honglin Yu,Mengqi Liu,Guodong Zhang,Fei Wang
As the key to open the Pandora’s box of gas efficient capture, water-based porous liquids have doubled the popular attention. Nevertheless, the synthesis of water-based porous liquids is a significant challenge due to the inherent limitation in the wettability of nanoporous hosts. In this work, Silicalite-1 was prepared by hydrothermal synthesis, based on which a water-based porous liquid of S-1-PL was successfully prepared, and CH 4 capture in the porous liquid via adsorption-absorption synergistic approach was evaluated. It was demonstrated that S-1-PL exhibited excellent stability and flowability, with a pore opening ratio up to 90 %. CH 4 capture capacity in S-1-PL with the solid content of 15 wt% was 0.57 mol/L, which was 2.6 times that in pure water system, demonstrating excellent CH 4 physisorption performance. When the adsorption-absorption synergistic approach was employed, CH 4 capture capacity increases to 1.88 mol/L with an increase by 229.8 %. In addition, a hydrate nano-promoter of −SO 3 - @PSNS was prepared to enhance hydration efficiency, which resulted in a notable enhancement in the hydration conversion rate, and it increases from 12.54 % to 61.99 % in the system of S-1-PL 15wt% , giving rise to a significant increase in CH 4 capture to 6.22 mol/L, which is 12.67 times that in the system of −SO 3 - @PSNS solution. These findings provide clear evidence for the first time on the exceptional adaptability of water-based porous liquid for the capture of CH 4 by adsorption-absorption synergistic approach, offering a new strategy for the emission reduction of CH 4 .
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CERAMICS INTERNATIONAL
·
2025
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IF 5.6
Jia Wang,Le Xin,Mingwei Zhang,Xin Geng,Ruihang Li,Pengchao Shao,Panpan Lyu,Hui Peng,Luchao Ren,Cuncheng Li
Microwave dielectric ceramics of Sr 2 SiO 4 incorporated with different contents of Ba 0.5 Sr 0.5 TiO 3 were prepared using a solid-phase reaction. Their phase composition, micro-structure evolution and dielectric properties were investigated systematically. The results reveal that increasing the x content to 50 wt% leads to greater lattice distortion and defects formation caused by ion substitution within the composite ceramics, resulting in an increase in the dielectric permittivity while a degradation in the Q value. As the x content continues to increase, the enhanced connectivity and ferroelectric properties caused by Ba 0.5 Sr 0.5 TiO 3 within the composite ceramics trigger a sharp increase in the dielectric permittivity. However, the deterioration in Q value is suppressed by the composite effect, and its value gradually increases. At the same time, structural transformations occur within the composites, possessing relaxation properties. Optimal microwave dielectric performance is achieved at x = 25 wt%, indicating balanced properties with ε r = 26.41, Q = 1578 (4.658 GHz), and tanδ = 0.001581.
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CHEMICAL ENGINEERING JOURNAL
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2024
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IF 13.3
Keming Zhang,Xianye Luo,Sihui Li,Xiaohe Tian,Qingnan Wang,Chenlu Liu,Yanting Tang,Xiaoting Feng,Rui Zhang,Shuangfeng Yin,Shaofei Wang
Developing high-performance H 2 /CH 4 separation membranes is of great potential for H 2 production in the petroleum industry. Incorporating nanofillers into a polymer matrix to form mixed matrix membranes (MMMs) can elevate selectivity and permeability, but poor polymer-filler interfacial compatibility and filler aggregation are formidable problems. Targeting this, we propose a novel approach by incorporating a metal–organic framework (MOF) gel, ZIF-8 gel, as the versatile filler to a high free volume polymer PIM-1 and investigate the H 2 /CH 4 separation capabilities of the MMMs. Benefiting from the gel network morphology of ZIF-8, they were dispersed evenly in the PIM-1 matrix. The interconnected gel network structure of ZIF-8 gel helped to construct continuous gas transport pathways in the polymer. As a result, the H 2 /CH 4 separation performance was notably improved, demonstrating a substantial increase in H 2 permeability by 78.9% (exceeding 6800 Barrer) and a 38.0% enhancement in H 2 /CH 4 selectivity at a ZIF-8 gel loading of 31.0 wt%. These improvements surpassed the upper bound established in 2008. The Maxwell and Lewis-Nielsen models were developed to clarify gas transport mechanisms across membranes, and the experimental data of ZIF-8 gel/PIM-1 was well-matched with the calculated results of the Lewis-Nielsen models. Adopting MOF gel as fillers may pave a new approach to design high-performance MMMs with interconnected transport pathways.
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FUEL
·
2024
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IF 6.7
Xiaoyan Xue,Yan Sun,Qiwen Sun,Weiren Bao,Zongsen Zhang,Liping Chang,Jiancheng Wang,Kechang Xie
The addition-esterification reaction of fatty acids and alkenes is an important method for replacing the Fischer-Speier esterification due to its 100 % atomic utilization. In this study, sec -hexyl acetate was synthesized through the addition-esterification of 1-hexene. At the same time, five different zinc-exchanged phosphotungstic acid catalysts were prepared using the ion exchange method, and their catalytic activities in the addition-esterification were tested and compared. Results indicate that the Zn 0.5 H 2.0 PW- I catalyst exhibits the best performance in six different catalysts, which is attributed to the synergistic effect of Brönsted and Lewis acids. The activity of catalysts is determined by the equilibrium relationship between Brönsted and Lewis acidity. In the addition-esterification of alkenes, the main activity center is the Brönsted acid site, while the Lewis acid site can improve the adsorption capacity of the catalyst for acetic acid molecules. Moreover, the preparation methods have a significant impact on the activity of catalysts. In addition, the in-situ FT-IR spectrum experiment confirms that the reaction rate of alkene isomerization is greater than that of addition-esterification, and a higher temperature is not conducive to the generation of acetate.
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Gas Science and Engineering
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2024
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IF 0
Xuebi Du,Dawei Shao,Yinhua Wan
Metal-organic frameworks (MOFs) have shown potential as nanofillers for the selective capture of specific gases in mixed matrix membranes (MMMs). This study introduces an efficient method, utilizing a mild (100 °C) reaction condition and a short reaction time (20 min), for the synthesis of MOF-808(Ce) nanocrystals. The MOF-808(Ce) that is obtained exhibits porous characteristics, a notable affinity for CO 2 , and robust intermolecular interactions with PIM-1. Furthermore, this study pioneers the incorporation of MOF-808(Ce) as a filler into PIM-1, with varying loadings, to create PIM/MOF-808 MMMs for the purpose of CO 2 separation. Consequently, the MMMs containing 2 wt% MOF-808(Ce) demonstrate high CO 2 permeability of 6854 Barrer and CO 2 /N 2 selectivity of 23.2, which is far surpasses 2008 upper bound from Robeson and approaches the refined 2019 upper bound from MeKenow. A comparative analysis demonstrates the efficacy of MOF-808(Ce) as a filler in PIM-1 for the purpose of CO 2 separation.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2025
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IF 9.7
Yiran Qian,Xiaoxi Chang,Mingyang Sun,Yunqi Chen,Jiachen Zang,Chenyan Lv,Guanghua Zhao,Tuo Zhang
Bioactive peptides have attracted significant attention for their potential health benefits; however, their oral administration is challenged by degradation from digestive proteases and limited intestinal absorption. In this study, we demonstrated the exceptional gastrointestinal stability of ferritin nanocages, which remained largely intact after 30 min of simulated gastric digestion and were highly resistant to intestinal proteolysis. Consistent with in vitro findings, orally administered ferritin successfully reached the intestinal tract without significant degradation in mice. We engineered a fusion protein by linking a glucagon-like peptide-1 (GLP-1) motif to the C-terminus of heteropolymer ferritin, generating HLG. Through Caco-2 monolayer assays, we confirmed that HLG absorption occurs primarily via TfR1-mediated endocytosis, followed by lysosomal trafficking and subsequent release of bioactive GLP-1. Oral administration of HLG significantly reduced blood glucose levels and food intake in type 2 diabetic mice, whereas the GLP-1 analog exenatide alone showed no such effects. These findings highlight the potential of ferritin-based nanocages as an effective oral delivery platform for bioactive peptides.
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PubMed
高影响因子
Cell Metabolism
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2025
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IF 30.9
Ming-Ming Wu,Yan-Chao Yang,Zhi-Qiang Hu,Jie-Yu Chang,Han Xiao,Chang Miao,Bo-Wen Zhang,Zhi-Xi He,Di Zhu,Yu-Ran Duan,Shuo Wang,Jian-Yu Liu,Zhan-Peng Guo,Yu Sun,Dan-Yang Liu,Miao Yu,Yue Zhang,Jian-Jun Mao,Shuai Jiang,Bing-Kun Zhang,Zhu Mei,Jun Gao,Chen Liang,Qiu-Shi Wang,Chang-Jiang Yu,Dan Zhao,Cheng-Hui Yan,Yue Li,Zhen-Wei Pan,Zheng Chen,Da-Qian Xu,Tong Liu,Yong Ji,Zhi-Ren Zhang
Immune checkpoint inhibitor (ICI) therapies increase the risk of metabolic syndrome; the underlying mechanisms remain elusive. We show that an anti-PD-1 antibody targets macrophage PD-1 to reduce energy expenditure without affecting food intake, augmenting the susceptibility of mice to high-fat diet (HFD)-induced obesity and systemic metabolic disorders. Mechanistically, lipopolysaccharide (LPS) activates Unc-51-like autophagy activating kinase 1 (ULK1) in a mammalian target of rapamycin (mTOR)-dependent manner. Activated ULK1 phosphorylates PD-1 at Thr250 to inhibit FBXO38-mediated PD-1 ubiquitination and degradation by disrupting FBXO38-PD-1 binding. Phosphorylated PD-1 interacts with inositol-requiring enzyme 1α (IRE1α) and attenuates IRE1α autophosphorylation to suppress endoplasmic reticulum (ER) stress-mediated inflammatory responses. Suppressing IRE1α alleviates HFD-induced metabolic disorders in macrophage-specific PD-1 knockout mice by rescuing the reduced energy expenditure. Our findings highlight the critical role of macrophage PD-1 at the intersection of immune checkpoint blockade, energy expenditure, and metabolic dysfunction. The underscored moonlighting function of macrophage PD-1 may provide a new rationale for combating ICI therapy- and HFD-induced metabolic diseases.
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PubMed
高影响因子
ACS Catalysis
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2025
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IF 13.1
Yanchun Shi,Jimei Zhang,Sihan Sun,Bi Wu,Lei Wang,Yulong Wu,Dingsheng Wang
Upgrading lignin-derived phenols to high-value arenes has garnered significant attention, while the major challenge lies in the selective cleavage of Caromatics–OH via hydroxyl hydrogenolysis. We systematically investigated the morphology-dependent properties of Ni@S-1 catalysts, encompassing their physicochemical characteristics, Ni nanoparticle properties, and the interaction between NiOx species and silicalite-1 (S-1) crystals as well as their performance in hydroxyl hydrogenolysis of vapor-phase m-cresol conversion. Both Ni@S-1 exhibited comparable Ni loading and crystal sizes but distinct morphologies, which originated from the complex intergrowth structures leading to variations in the dispersion and the location of Ni nanoparticles and significant differences in the shape-selective catalysis based on the confinement effect of S-1 channels for the vertical adsorption of m-cresol. Ellipsoidal Ni@S-1-Ell achieved m-cresol conversion of 96.9% (model reaction) along with hydrogenolysis products’ yield of 94.0%, which was 6.97 times in conversion and 22.38 times in yield of hydrogenolysis products than those of cylindrical Ni@S-1-Cyl under identical reaction conditions at 300 °C, 2.5 atm, and a feed rate of 6.0 g[m-cresol]/g[catalyst]·h.
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